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Volumn 583, Issue , 2014, Pages 16-20

Activity increase in EpoR and Epo expression by intranasal recombinant human erythropoietin (rhEpo) administration in ischemic hippocampi of adult rats

Author keywords

EpoR phosphorylation; Erythropoietin; Intranasal delivery; Ischemia; Neuroprotection

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; RECOMBINANT ERYTHROPOIETIN; NEUROPROTECTIVE AGENT; RECOMBINANT PROTEIN; TYROSINE;

EID: 84907517619     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.09.013     Document Type: Article
Times cited : (14)

References (33)
  • 1
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • Metha S.L., Manhas N., Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res. Rev. 2007, 54:34-66.
    • (2007) Brain Res. Rev. , vol.54 , pp. 34-66
    • Metha, S.L.1    Manhas, N.2    Raghubir, R.3
  • 3
    • 33646357765 scopus 로고    scopus 로고
    • Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms
    • Zhang F., Signore A.P., Zhou Z., Wang S., Cao G., Chen J. Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms. J. Neurosci. Res. 2006, 83:1241-1251.
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1241-1251
    • Zhang, F.1    Signore, A.P.2    Zhou, Z.3    Wang, S.4    Cao, G.5    Chen, J.6
  • 4
    • 0035079692 scopus 로고    scopus 로고
    • The biology of erythropoietin in the central nervous system and its neurotrophic and neuroprotective potential
    • Dame C., Juul C.E., Christensen R.D. The biology of erythropoietin in the central nervous system and its neurotrophic and neuroprotective potential. Biol. Neonate. 2001, 79:228-235.
    • (2001) Biol. Neonate. , vol.79 , pp. 228-235
    • Dame, C.1    Juul, C.E.2    Christensen, R.D.3
  • 6
    • 0027400859 scopus 로고
    • Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors
    • Miura O., Cleveland J.L., Ihle J.N. Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors. Mol. Cell. Biol. 1993, 13:1788-1795.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1788-1795
    • Miura, O.1    Cleveland, J.L.2    Ihle, J.N.3
  • 7
    • 0034982679 scopus 로고    scopus 로고
    • The erythropoietin receptor
    • Mulcahy L. The erythropoietin receptor. Semin. Oncol. 2001, 28:19-23.
    • (2001) Semin. Oncol. , vol.28 , pp. 19-23
    • Mulcahy, L.1
  • 8
    • 11244333356 scopus 로고    scopus 로고
    • New avenues of exploration for erythropoietin
    • Maiese K., Li F., Chong Z.Z. New avenues of exploration for erythropoietin. JAMA 2005, 293:90-95.
    • (2005) JAMA , vol.293 , pp. 90-95
    • Maiese, K.1    Li, F.2    Chong, Z.Z.3
  • 9
    • 53549097076 scopus 로고    scopus 로고
    • Erythropoietin-mediated tissue protection: reducing collateral damage from the primary injury response
    • Brines M., Cerami A. Erythropoietin-mediated tissue protection: reducing collateral damage from the primary injury response. J. Intern. Med. 2008, 264:405-432.
    • (2008) J. Intern. Med. , vol.264 , pp. 405-432
    • Brines, M.1    Cerami, A.2
  • 11
    • 77955851806 scopus 로고    scopus 로고
    • Enhanced delivery of erythropoietin across the blood-brain barrier for neuroprotection against ischemic neuronal injury
    • Zhang F., Xing J., Liou A.K., Wang S., Gan Y., Luo Y., Ji X., Stetler R.A., Chen J., Cao G. Enhanced delivery of erythropoietin across the blood-brain barrier for neuroprotection against ischemic neuronal injury. Transl. Stroke Res. 2010, 1:113-121.
    • (2010) Transl. Stroke Res. , vol.1 , pp. 113-121
    • Zhang, F.1    Xing, J.2    Liou, A.K.3    Wang, S.4    Gan, Y.5    Luo, Y.6    Ji, X.7    Stetler, R.A.8    Chen, J.9    Cao, G.10
  • 14
    • 23744459392 scopus 로고    scopus 로고
    • Intranasal recombinant human erythropoietin protects rats against focal cerebral ischemia
    • Yu Y.P., Xu Q.Q., Zhang Q., Zhang W.P., Zhang L.H., Wei E.Q. Intranasal recombinant human erythropoietin protects rats against focal cerebral ischemia. Neurosci. Lett. 2005, 387:5-10.
    • (2005) Neurosci. Lett. , vol.387 , pp. 5-10
    • Yu, Y.P.1    Xu, Q.Q.2    Zhang, Q.3    Zhang, W.P.4    Zhang, L.H.5    Wei, E.Q.6
  • 15
    • 36348979571 scopus 로고    scopus 로고
    • Intranasal administration of recombinant human erythropoietin exerts neuroprotective effects on post-ischemic brain injury in Mongolian gerbils
    • Sosa I., García Rodríguez J.C., Santana J., Subiros N., González C., Rodríguez Y., Rodríguez J. Intranasal administration of recombinant human erythropoietin exerts neuroprotective effects on post-ischemic brain injury in Mongolian gerbils. Pharmacologyonline 2006, 1:100-112.
    • (2006) Pharmacologyonline , vol.1 , pp. 100-112
    • Sosa, I.1    García Rodríguez, J.C.2    Santana, J.3    Subiros, N.4    González, C.5    Rodríguez, Y.6    Rodríguez, J.7
  • 17
    • 0021244677 scopus 로고
    • Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model
    • Smith M.L., Bendek G., Dahlgren N., Rosen I., Wieloch T., Siesjo B.K. Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model. Acta Neurol. Scand. 1984, 69:385-401.
    • (1984) Acta Neurol. Scand. , vol.69 , pp. 385-401
    • Smith, M.L.1    Bendek, G.2    Dahlgren, N.3    Rosen, I.4    Wieloch, T.5    Siesjo, B.K.6
  • 20
    • 0034641710 scopus 로고    scopus 로고
    • Erythropoietin cross the blood brain barrier to protect against experimental brain injury
    • Brines M.L., Ghezzi P., Keenan S. Erythropoietin cross the blood brain barrier to protect against experimental brain injury. PNAS 2000, 97:10526-10531.
    • (2000) PNAS , vol.97 , pp. 10526-10531
    • Brines, M.L.1    Ghezzi, P.2    Keenan, S.3
  • 21
    • 0037064261 scopus 로고    scopus 로고
    • Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis
    • Agnello D., Bigini P., Villa P., Mennini T., Cerami A., Brines M.L., Ghezzi P. Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res. 2002, 952:128-134.
    • (2002) Brain Res. , vol.952 , pp. 128-134
    • Agnello, D.1    Bigini, P.2    Villa, P.3    Mennini, T.4    Cerami, A.5    Brines, M.L.6    Ghezzi, P.7
  • 22
    • 77955487488 scopus 로고    scopus 로고
    • The science of stroke: mechanisms in search of treatments
    • Moskowitz M.A., Lo E.H., Iadecola C. The science of stroke: mechanisms in search of treatments. Neuron 2010, 67:181-198.
    • (2010) Neuron , vol.67 , pp. 181-198
    • Moskowitz, M.A.1    Lo, E.H.2    Iadecola, C.3
  • 23
    • 0021925444 scopus 로고
    • An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide
    • Jones K., Senft J.A. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. J. Histochem. Cytochem. 1985, 33:77-79.
    • (1985) J. Histochem. Cytochem. , vol.33 , pp. 77-79
    • Jones, K.1    Senft, J.A.2
  • 24
    • 80052342942 scopus 로고    scopus 로고
    • Dose-dependent neurorestorative effects of delayed treatment of traumatic brain injury with recombinant human erythropoietin in rats
    • Meng Y., Xiong Y., Mahmood A., Zhang Y., Qu C., Chopp M. Dose-dependent neurorestorative effects of delayed treatment of traumatic brain injury with recombinant human erythropoietin in rats. J. Neurosurg. 2011, 115:550-560.
    • (2011) J. Neurosurg. , vol.115 , pp. 550-560
    • Meng, Y.1    Xiong, Y.2    Mahmood, A.3    Zhang, Y.4    Qu, C.5    Chopp, M.6
  • 26
    • 34548501737 scopus 로고    scopus 로고
    • Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation
    • Chen Z.Y., Asavaritikrai P., Prchal J.T., Noguchi C.T. Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation. J. Biol. Chem. 2007, 282:25875-25883.
    • (2007) J. Biol. Chem. , vol.282 , pp. 25875-25883
    • Chen, Z.Y.1    Asavaritikrai, P.2    Prchal, J.T.3    Noguchi, C.T.4
  • 27
    • 15244341057 scopus 로고    scopus 로고
    • Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats
    • Sola A., Rogido M., Lee B.H., Genetta T., Wen T.C. Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats. Pediatr. Res. 2005, 57:481-487.
    • (2005) Pediatr. Res. , vol.57 , pp. 481-487
    • Sola, A.1    Rogido, M.2    Lee, B.H.3    Genetta, T.4    Wen, T.C.5
  • 28
    • 0141482000 scopus 로고    scopus 로고
    • Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury
    • Campana W.M., Myers R.R. Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury. Eur. J. Neurosci. 2003, 18:1497-1506.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 1497-1506
    • Campana, W.M.1    Myers, R.R.2
  • 29
    • 84890408530 scopus 로고    scopus 로고
    • Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor
    • Hellewell S.C., Ya E.B., Alwis D.S., Bye N., Morganti-Kossmann M.C. Erythropoietin improves motor and cognitive deficit, axonal pathology, and neuroinflammation in a combined model of diffuse traumatic brain injury and hypoxia, in association with upregulation of the erythropoietin receptor. J. Neuroinflamm. 2013, 18:10-156.
    • (2013) J. Neuroinflamm. , vol.18 , pp. 10-156
    • Hellewell, S.C.1    Ya, E.B.2    Alwis, D.S.3    Bye, N.4    Morganti-Kossmann, M.C.5
  • 30
    • 0035914398 scopus 로고    scopus 로고
    • Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia
    • Kawakami M., Sekiguchi M., Sato K., Kozaki S., Takahashi M. Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia. J. Biol. Chem. 2001, 276:39469-39475.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39469-39475
    • Kawakami, M.1    Sekiguchi, M.2    Sato, K.3    Kozaki, S.4    Takahashi, M.5
  • 31
    • 3042791260 scopus 로고    scopus 로고
    • Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I
    • Digicaylioglu M., Garden G., Timberlake S., Fletcher L., Lipton S.A. Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I. PNAS 2004, 101:9855-9860.
    • (2004) PNAS , vol.101 , pp. 9855-9860
    • Digicaylioglu, M.1    Garden, G.2    Timberlake, S.3    Fletcher, L.4    Lipton, S.A.5
  • 32
    • 78049279683 scopus 로고    scopus 로고
    • Erythropoietin 2nd cerebral protection after acute injuries: a double-edged sword?
    • Velly L., Pellegrini L., Guillet B., Bruder N., Pisano P. Erythropoietin 2nd cerebral protection after acute injuries: a double-edged sword?. Pharmacol. Ther. 2010, 128:445-459.
    • (2010) Pharmacol. Ther. , vol.128 , pp. 445-459
    • Velly, L.1    Pellegrini, L.2    Guillet, B.3    Bruder, N.4    Pisano, P.5
  • 33
    • 34648843243 scopus 로고    scopus 로고
    • Pathologically activated therapeutics for neuroprotection
    • Lipton S.A. Pathologically activated therapeutics for neuroprotection. Nat. Rev. Neurosci. 2007, 8:803-808.
    • (2007) Nat. Rev. Neurosci. , vol.8 , pp. 803-808
    • Lipton, S.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.