Design, synthesis and SAR studies of NAD analogues as potent inhibitors towards CD38 NADase

Molecules

Volumn 19, Issue 10, 2014, Pages 15754-15767

  Zhang, Lihe ^a   Zhang, liangren ^a   Wang, Shengjun ^a   Zhu, Wenjie ^b   Wang, Xuan ^a   Li, Jianguo ^a   Zhang, Kehui ^a   Zhao, Yong Juan ^b   Lee, Hon Cheung ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

CD38; Inhibitors; NAD analogues; Synthesis

Indexed keywords

CD38 ANTIGEN; ENZYME INHIBITOR; GUANINE NUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE GUANINE DINUCLEOTIDE; PROTEIN BINDING;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; ENZYME ACTIVATION; ENZYME SPECIFICITY; SYNTHESIS;

ANTIGENS, CD38; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; ENZYME ACTIVATION; ENZYME INHIBITORS; GUANINE NUCLEOTIDES; MOLECULAR STRUCTURE; NAD; PROTEIN BINDING; SUBSTRATE SPECIFICITY;

EID: 84907509269     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules191015754     Document Type: Article

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