Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38

Journal of Biological Chemistry

Volumn 282, Issue 8, 2007, Pages 5853-5861

  Liu, Qun ^a   Kriksunov, Irina A ^a   Graeff, Richard ^b   Hon, Cheung Lee ^b,c   Hao, Quan ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM MESSENGERS; CATALYTIC SITES; MULTIFUNCTIONAL ECTOENZYMES;

BINDING SITES; CATALYSIS; COMPLEXATION; CONFORMATIONS; CRYSTAL STRUCTURE; ENZYMES; HYDROGEN BONDS; HYDROLYSIS;

NUCLEOTIDES;

ASPARTIC ACID; CALCIUM; CD38 ANTIGEN; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; CYCLIC GUANOSINE DIPHOSPHATE RIBOSE; DIPEPTIDE; ENZYME; GLUTAMIC ACID; HYDROGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE GUANINE DINUCLEOTIDE; NUCLEOTIDE DERIVATIVE; RIBOSE; UNCLASSIFIED DRUG; CD38 PROTEIN, HUMAN; DRUG DERIVATIVE; MEMBRANE PROTEIN;

ARTICLE; BIOSYNTHESIS; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; STRUCTURE ANALYSIS; BINDING SITE; CALCIUM SIGNALING; CHEMISTRY; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANTIGENS, CD38; BINDING SITES; CALCIUM SIGNALING; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYCLIC ADP-RIBOSE; HUMANS; MEMBRANE GLYCOPROTEINS; NAD; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 34047231298     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M609093200     Document Type: Article

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