-
1
-
-
79952613370
-
Systematic review of medical treatment in melanoma: Current status and future prospects
-
Garbe C, Eigentler TK, Keilholz U, et al. Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist, 2011,16:5-24.
-
(2011)
Oncologist
, vol.16
, pp. 5-24
-
-
Garbe, C.1
Eigentler, T.K.2
Keilholz, U.3
-
2
-
-
80052536175
-
New drugs in melanoma: It's a whole new world
-
Eggermont AM, Robert C. New drugs in melanoma: it's a whole new world. Eur J Cancer, 2011,47:2150-2157.
-
(2011)
Eur J Cancer
, vol.47
, pp. 2150-2157
-
-
Eggermont, A.M.1
Robert, C.2
-
3
-
-
84873819555
-
Which drug, and when, for patients with BRAFmutant melanoma?
-
Jang S, Atkins MB. Which drug, and when, for patients with BRAFmutant melanoma? Lancet Oncol, 2013,14:e60-e69.
-
(2013)
Lancet Oncol
, vol.14
, pp. e60-e69
-
-
Jang, S.1
Atkins, M.B.2
-
4
-
-
84905650559
-
The incidences and mortalities of major cancers in China, 2010
-
Chen W, Zheng R, Zhang S, et al. The incidences and mortalities of major cancers in China, 2010. Chin J Cancer, 2014,33:402-405.
-
(2014)
Chin J Cancer
, vol.33
, pp. 402-405
-
-
Chen, W.1
Zheng, R.2
Zhang, S.3
-
5
-
-
84871858163
-
Melanoma in immunosuppressed patients
-
Kubica AW, Brewer JD. Melanoma in immunosuppressed patients. Mayo Clin Proc, 2012,87:991-1003.
-
(2012)
Mayo Clin Proc
, vol.87
, pp. 991-1003
-
-
Kubica, A.W.1
Brewer, J.D.2
-
6
-
-
84884704400
-
CTLA-4 and autoimmunity: New insights into the dual regulator of tolerance
-
Romo-Tena J, Gomez-Martin D, Alcocer-Varela J. CTLA-4 and autoimmunity: new insights into the dual regulator of tolerance. Autoimmun Rev, 2013,12:1171-1176.
-
(2013)
Autoimmun Rev
, vol.12
, pp. 1171-1176
-
-
Romo-Tena, J.1
Gomez-Martin, D.2
Alcocer-Varela, J.3
-
7
-
-
84907498837
-
The impact of clinical response to anti-CTLA4 treatment on overall survival (OS) in metastatic melanoma (MM)
-
Available at
-
Feng XL, Smylie M, Cheng T, et al. The impact of clinical response to anti-CTLA4 treatment on overall survival (OS) in metastatic melanoma (MM). J Clin Oncol (meeting abstracts), 2014,32:15-suppl 9080. Available at: http://meeting.ascopubs.org/cgi/content/ abstract/32/15_suppl/9080?sid=55766fbf-0d39-4eda-8665-85ff1fac2f85.
-
(2014)
J Clin Oncol (meeting abstracts)
, vol.32
, Issue.15
-
-
Feng, X.L.1
Smylie, M.2
Cheng, T.3
-
8
-
-
84862494584
-
Assessment of association between braf-v600e mutation status in melanomas and clinical response to ipilimumab
-
Shahabi V, Whitney G, Hamid O, et al. Assessment of association between braf-v600e mutation status in melanomas and clinical response to ipilimumab. Cancer Immunol Immunother, 2012,61:733-737.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 733-737
-
-
Shahabi, V.1
Whitney, G.2
Hamid, O.3
-
9
-
-
84876678621
-
Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: Detailed safety analysis from a phase 3 trial in patients with advanced melanoma
-
Weber JS, Dummer R, de Pril V, et al. Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanoma. Cancer, 2013,119:1675-1682.
-
(2013)
Cancer
, vol.119
, pp. 1675-1682
-
-
Weber, J.S.1
Dummer, R.2
De Pril, V.3
-
10
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med, 2010,363:711-723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'day, S.J.2
McDermott, D.F.3
-
11
-
-
84894277027
-
Ipilimumab in the treatment of metastatic melanoma: A summary of recent studies
-
Ascierto PA. Ipilimumab in the treatment of metastatic melanoma: a summary of recent studies. Tumori, 2013,99:302e-305e.
-
(2013)
Tumori
, vol.99
, pp. 302e-305e
-
-
Ascierto, P.A.1
-
12
-
-
84911976670
-
Ipilimumab, not just another anti-cancer therapy: Hypophysitis as side effect illustrated by four case-reports
-
Feb 21, Epub ahead of print
-
Marlier J, Cocquyt V, Brochez L, et al. Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports. Endocrine, 2014 Feb 21. [Epub ahead of print].
-
(2014)
Endocrine
-
-
Marlier, J.1
Cocquyt, V.2
Brochez, L.3
-
13
-
-
84888226962
-
Endocrine sideeffects of anti-cancer drugs: MAbs and pituitary dysfunction: Clinical evidence and pathogenic hypotheses
-
Torino F, Barnabei A, Paragliola RM, et al. Endocrine sideeffects of anti-cancer drugs: mAbs and pituitary dysfunction: clinical evidence and pathogenic hypotheses. Eur J Endocrinol, 2013,169:R153-164.
-
(2013)
Eur J Endocrinol
, vol.169
, pp. R153-164
-
-
Torino, F.1
Barnabei, A.2
Paragliola, R.M.3
-
14
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med, 2011,364:2517-2526.
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
15
-
-
84907549266
-
A randomized phase II study of ipilimumab (IPI) with carboplatin and paclitaxel (CP) in patients with unresectable stage III or IV metastatic melanoma (MM)
-
meeting abstracts, Available at
-
Jamal R, Belanger K, Friedmann JE, et al. A randomized phase II study of ipilimumab (IPI) with carboplatin and paclitaxel (CP) in patients with unresectable stage III or IV metastatic melanoma (MM). J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9066. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_ suppl/9066?sid=d88fee02-9cc2-48d6-b947-1a12933b8ea1.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Jamal, R.1
Belanger, K.2
Friedmann, J.E.3
-
16
-
-
84901340078
-
Outcomes of patients with metastatic melanoma treated with immunotherapy prior to or after BRAF inhibitors
-
Ackerman A, Klein O, McDermott DF, et al. Outcomes of patients with metastatic melanoma treated with immunotherapy prior to or after BRAF inhibitors. Cancer, 2014,120:1695-1701.
-
(2014)
Cancer
, vol.120
, pp. 1695-1701
-
-
Ackerman, A.1
Klein, O.2
McDermott, D.F.3
-
17
-
-
84907498836
-
Single-center experience in French Temporary Authorization for Use (TAU) metastatic melanoma program with ipilimumab
-
meeting abstracts, Available at
-
Chasset F, Pagès C, Biard L, et al. Single-center experience in French Temporary Authorization for Use (TAU) metastatic melanoma program with ipilimumab. J Clin Oncol (meeting abstracts), 2014,32:15_supple 20034. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/ e20034?sid=a4a9adcb-36ee-43db-8df6-66972e5e1156.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Chasset, F.1
Pagès, C.2
Biard, L.3
-
18
-
-
84907521156
-
Ipilimumab versus placebo after complete resection of stage III melanoma: Initial efficacy and safety results from the EORTC 18071 phase III trial
-
meeting abstracts, Available at
-
Eggermont AM, Grob JJ, Dummer R, et al. Ipilimumab versus placebo after complete resection of stage III melanoma: initial efficacy and safety results from the EORTC 18071 phase III trial. J Clin Oncol (meeting abstracts), 2014,32:18_suppl LBA9008. Available at: http://meeting.ascopubs.org/cgi/content/ abstract/32/18_suppl/LBA9008?sid=e65ba47c-6221-43c7-ae65-f680998d22bd.
-
(2014)
J Clin Oncol
, vol.32
, Issue.18
-
-
Eggermont, A.M.1
Grob, J.J.2
Dummer, R.3
-
19
-
-
32644467549
-
Antitumor activity in melanoma and anti-self responses in a phase I trial with the anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206
-
Ribas A, Camacho LH, Lopez-Berestein G, et al. Antitumor activity in melanoma and anti-self responses in a phase I trial with the anticytotoxic T lymphocyte-associated antigen 4 monoclonal antibody CP-675,206. J Clin Oncol, 2005,23:8968-8977.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8968-8977
-
-
Ribas, A.1
Camacho, L.H.2
Lopez-Berestein, G.3
-
20
-
-
76049092889
-
Phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma
-
Kirkwood JM, Lorigan P, Hersey P, et al. Phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma. Clin Cancer Res, 2010,16:1042-1048.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1042-1048
-
-
Kirkwood, J.M.1
Lorigan, P.2
Hersey, P.3
-
21
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
Ribas A, Kefford R, Marshall MA, et al. Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol, 2013,31:616-622.
-
(2013)
J Clin Oncol
, vol.31
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
-
22
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir ME, Butte MJ, Freeman GJ, et al. PD-1 and its ligands in tolerance and immunity. Ann Rev Immunol, 2008,26:677-704.
-
(2008)
Ann Rev Immunol
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
-
23
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med, 2013,369:134-144.
-
(2013)
N Engl J Med
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
-
24
-
-
84872514622
-
Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody
-
Lipson EJ, Sharfman WH, Drake CG, et al. Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody. Clin Cancer Res, 2013,19:462-468.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 462-468
-
-
Lipson, E.J.1
Sharfman, W.H.2
Drake, C.G.3
-
25
-
-
84892866206
-
Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or-naive melanoma
-
Weber JS, Kudchadkar RR, Yu B, et al. Safety, efficacy, and biomarkers of nivolumab with vaccine in ipilimumab-refractory or-naive melanoma. J Clin Oncol, 2013,31:4311-4318.
-
(2013)
J Clin Oncol
, vol.31
, pp. 4311-4318
-
-
Weber, J.S.1
Kudchadkar, R.R.2
Yu, B.3
-
26
-
-
84907558390
-
Long-term survival of ipilimumab-naive patients (pts) with advanced melanoma (MEL) treated with nivolumab (anti-PD-1, BMS-936558, ONO-4538) in a phase I trial
-
meeting abstracts, Available at
-
Hodi FS, Sznol M, Kluger HM, et al. Long-term survival of ipilimumab-naive patients (pts) with advanced melanoma (MEL) treated with nivolumab (anti-PD-1, BMS-936558, ONO-4538) in a phase I trial. J Clin Oncol (meeting abstracts), 2014,32:15_ suppl 9002. Available at: http://meeting.ascopubs.org/cgi/content/ abstract/32/15_suppl/9002?sid=5fe47f07-074b-4963-b8c8-2bdfb7c44af7.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Hodi, F.S.1
Sznol, M.2
Kluger, H.M.3
-
27
-
-
84908299923
-
Updated survival, toxicity, and biomarkers of nivolumab with/without peptide vaccine in patients naive to, or progressed on, ipilimumab (IPI)
-
meeting abstracts, Avalialbe at
-
Weber JS, Kudchadkar RR, Gibney GT, et al. Updated survival, toxicity, and biomarkers of nivolumab with/without peptide vaccine in patients naive to, or progressed on, ipilimumab (IPI). J Clin Oncol (meeting abstracts), 2014,32:15_suppl 3009. Avalialbe at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/3009?sid=79ccfaca-ae72-4c86-a796-a9d47d32505a.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Weber, J.S.1
Kudchadkar, R.R.2
Gibney, G.T.3
-
28
-
-
84908354848
-
Anti-programmed-deathreceptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
-
Jul 14. doi: 10.1016/S0140-6736(14) 60958-2. [Epub ahead of print]
-
Robert C, Ribas A, Wolchok JD, et al. Anti-programmed-deathreceptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet, 2014 Jul 14. doi: 10.1016/S0140-6736(14) 60958-2. [Epub ahead of print].
-
(2014)
Lancet
-
-
Robert, C.1
Ribas, A.2
Wolchok, J.D.3
-
29
-
-
84907543029
-
Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL)
-
meeting abstracts, Available at
-
Ribas A, Hodi FS, Kefford R, et al. Efficacy and safety of the anti-PD-1 monoclonal antibody MK-3475 in 411 patients (pts) with melanoma (MEL). J Clin Oncol (meeting abstracts), 2014,32:18_ suppl LBA9000. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/18_suppl/LBA9000?sid=53482d36-be89-408e-a182-31dc8af59124.
-
(2014)
J Clin Oncol
, vol.32
, Issue.18
-
-
Ribas, A.1
Hodi, F.S.2
Kefford, R.3
-
30
-
-
84907498839
-
Randomized comparison of two doses of the anti-PD-1 monoclonal antibody MK-3475 for ipilimumab-refractory (IPI-R) and ipi-naive (IPI-N) melanoma (MEL)
-
meeting abstracts, Available at
-
Hamid O, Robert C, Ribas A, et al. Randomized comparison of two doses of the anti-PD-1 monoclonal antibody MK-3475 for ipilimumab-refractory (IPI-R) and ipi-naive (IPI-N) melanoma (MEL). J Clin Oncol (meeting abstracts), 2014,32:15_suppl 3000. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/3000?sid=a0af207c-9694-4432-96ee-405a3816376e.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Hamid, O.1
Robert, C.2
Ribas, A.3
-
31
-
-
77953715389
-
4-1BB as a therapeutic target for human disease
-
Lee SW, Croft M. 4-1BB as a therapeutic target for human disease. Adv Exp Med Biol, 2009,647:120-129.
-
(2009)
Adv Exp Med Biol
, vol.647
, pp. 120-129
-
-
Lee, S.W.1
Croft, M.2
-
32
-
-
84884822262
-
Immunotherapy of melanoma with the immune costimulatory monoclonal antibodies targeting CD137
-
Liu SYLY. Immunotherapy of melanoma with the immune costimulatory monoclonal antibodies targeting CD137. Clin Pharmacol, 2013,5:47-53.
-
(2013)
Clin Pharmacol
, vol.5
, pp. 47-53
-
-
Liu, L.Y.1
-
33
-
-
84907498834
-
Blocking immunosuppressive checkpoints for glioma therapy: The more the merrier
-
May 30. [Epub ahead of print]
-
Castro MG, Baker GJM, Lowenstein PR. Blocking immunosuppressive checkpoints for glioma therapy: the more the merrier! Clin Cancer Res, 2014 May 30. [Epub ahead of print].
-
(2014)
Clin Cancer Res
-
-
Castro, M.G.1
Baker, G.J.M.2
Lowenstein, P.R.3
-
34
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med, 2013,369:122-133.
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
35
-
-
84907498833
-
Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL)
-
meeting abstracts, Available at
-
Sznol M, M. Kluger HM, Margaret K, et al. Survival, response duration, and activity by BRAF mutation (MT) status of nivolumab (NIVO, anti-PD-1, BMS-936558, ONO-4538) and ipilimumab (IPI) concurrent therapy in advanced melanoma (MEL). J Clin Oncol (meeting abstracts), 2014,32:18_suppl LBA9003. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/18_suppl/LBA9003?sid=96f27b34-e1a8-4ea7-8851-21476aa16fcf.
-
(2014)
J Clin Oncol
, vol.32
, Issue.18
-
-
Sznol, M.1
Kluger, M.2
Hm, M.K.3
-
36
-
-
84904521016
-
Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-alpha in patients with metastatic melanoma: A randomised "proof-of-principle" phase II study
-
de Rosa F, Ridolfi L, Ridolfi R, et al. Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-alpha in patients with metastatic melanoma: a randomised "proof-of-principle" phase II study. J Transl Med, 2014, 12:209.
-
(2014)
J Transl Med
, vol.12
, pp. 209
-
-
De Rosa, F.1
Ridolfi, L.2
Ridolfi, R.3
-
37
-
-
84880755387
-
Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: Phase II randomized study results
-
Vansteenkiste J, Zielinski M, Linder A, et al. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. J Clin Oncol, 2013,31:2396-2403.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2396-2403
-
-
Vansteenkiste, J.1
Zielinski, M.2
Linder, A.3
-
39
-
-
84892426495
-
Dendritic cell-based vaccines: Shining the spotlight on signal 3
-
Linette GP, Carreno BM. Dendritic cell-based vaccines: shining the spotlight on signal 3. Oncoimmunology, 2013,2:e26512.
-
(2013)
Oncoimmunology
, vol.2
-
-
Linette, G.P.1
Carreno, B.M.2
-
40
-
-
84893451553
-
Tap cells, the chilean dendritic cell vaccine against melanoma and prostate cancer
-
Salazar-Onfray F, Pereda C, Reyes D, et al. Tap cells, the chilean dendritic cell vaccine against melanoma and prostate cancer. Biol Res, 2013,46:431-440.
-
(2013)
Biol Res
, vol.46
, pp. 431-440
-
-
Salazar-Onfray, F.1
Pereda, C.2
Reyes, D.3
-
41
-
-
84864031681
-
Phase II clinical trial of autologous dendritic cell vaccine with immunologic adjuvant in cutaneous melanoma patients
-
Baldueva IA, Novik AV, Moiseenko VM, et al. Phase II clinical trial of autologous dendritic cell vaccine with immunologic adjuvant in cutaneous melanoma patients. Vopr Onkol, 2012,58:212-221.
-
(2012)
Vopr Onkol
, vol.58
, pp. 212-221
-
-
Baldueva, I.A.1
Novik, A.V.2
Moiseenko, V.M.3
-
42
-
-
84907498832
-
-
[in Russian]
-
[in Russian]
-
-
-
-
43
-
-
84879679031
-
Melanoma immunotherapy using mature dcs expressing the constitutive proteasome
-
Dannull J, Haley NR, Archer G, et al. Melanoma immunotherapy using mature dcs expressing the constitutive proteasome. J Clin Invest, 2013,123:3135-3145.
-
(2013)
J Clin Invest
, vol.123
, pp. 3135-3145
-
-
Dannull, J.1
Haley, N.R.2
Archer, G.3
-
44
-
-
84867552067
-
Metastatic melanoma patients treated with dendritic cell vaccination, interleukin-2 and metronomic cyclophosphamide: Results from a phase II trial
-
Ellebaek E, Engell-Noerregaard L, Iversen TZ, et al. Metastatic melanoma patients treated with dendritic cell vaccination, interleukin-2 and metronomic cyclophosphamide: results from a phase II trial. Cancer Immunol Immunother, 2012,61:1791-1804.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1791-1804
-
-
Ellebaek, E.1
Engell-Noerregaard, L.2
Iversen, T.Z.3
-
45
-
-
84866458433
-
Dendritic cell-based vaccination in metastatic melanoma patients: Phase II clinical trial
-
Oshita C, Takikawa M, Kume A, et al. Dendritic cell-based vaccination in metastatic melanoma patients: phase II clinical trial. Oncol Rep, 2012,28:1131-1138.
-
(2012)
Oncol Rep
, vol.28
, pp. 1131-1138
-
-
Oshita, C.1
Takikawa, M.2
Kume, A.3
-
46
-
-
0033579934
-
Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1
-
Marchand M, van Baren N, Weynants P, et al. Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1. Int J Cancer, 1999,80:219-230.
-
(1999)
Int J Cancer
, vol.80
, pp. 219-230
-
-
Marchand, M.1
Van Baren, N.2
Weynants, P.3
-
47
-
-
84864380076
-
MAGE-A antigens as targets in tumour therapy
-
Meek DW, Marcar L. MAGE-A antigens as targets in tumour therapy. Cancer Lett, 2012,324:126-132.
-
(2012)
Cancer Lett
, vol.324
, pp. 126-132
-
-
Meek, D.W.1
Marcar, L.2
-
48
-
-
27144514758
-
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma
-
Kruit WH, van Ojik HH, Brichard VG, et al. Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma. Int J Cancer, 2005,117:596-604.
-
(2005)
Int J Cancer
, vol.117
, pp. 596-604
-
-
Kruit, W.H.1
Van Ojik, H.H.2
Brichard, V.G.3
-
49
-
-
84880730418
-
Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: Results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma
-
Kruit WH, Suciu S, Dreno B, et al. Selection of immunostimulant AS15 for active immunization with MAGE-A3 protein: results of a randomized phase II study of the European Organisation for Research and Treatment of Cancer Melanoma Group in Metastatic Melanoma. J Clin Oncol, 2013,31:2413-2420.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2413-2420
-
-
Kruit, W.H.1
Suciu, S.2
Dreno, B.3
-
50
-
-
84907498831
-
GSK cancer vaccine disappoints in melanoma trial
-
Sept 5, Aviable at
-
Ben H. GSK cancer vaccine disappoints in melanoma trial. Reuters, 2013 Sept 5. Aviable at: http://www.reuters.com/article/2013/09/05/ us-glaxosmithkline-melanoma-idusbre98406w20130905.
-
(2013)
Reuters
-
-
Ben, H.1
-
51
-
-
0037295403
-
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties
-
Liu BL, Han ZQ, Branston RH, et al. ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour properties. Gene Ther, 2003,10:292-303.
-
(2003)
Gene Ther
, vol.10
, pp. 292-303
-
-
Liu, B.L.1
Han, Z.Q.2
Branston, R.H.3
-
52
-
-
73349133717
-
Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor encoding, second-generation oncolytic herpes virus in patients with unresectable metastatic melanoma
-
Senzer NNKH, Amatruda T, Nemunaitis M, et al. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor encoding, second-generation oncolytic herpes virus in patients with unresectable metastatic melanoma. J Clin Oncol, 2009,27:5763-5771.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5763-5771
-
-
Senzer, N.N.K.H.1
Amatruda, T.2
Nemunaitis, M.3
-
53
-
-
84907521153
-
Primary overall survival (OS) from OPTiM, a randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma
-
meeting abstracts, Available at
-
Kaufman HL, Andtbacka RHI, Collichio FA, et al. Primary overall survival (OS) from OPTiM, a randomized phase III trial of talimogene laherparepvec (T-VEC) versus subcutaneous (SC) granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment (tx) of unresected stage IIIB/C and IV melanoma. J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9008a. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/9008a?sid=8e6e0101-4d63-4680-a3f3-b910f424c05c.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Kaufman, H.L.1
Andtbacka, R.H.I.2
Collichio, F.A.3
-
54
-
-
84907498830
-
Update-1 Amgen melanoma drug fails to improve overall survival rates
-
Apr 4, Aviable at
-
Update-1 Amgen melanoma drug fails to improve overall survival rates. Reuters, 2014 Apr 4. Aviable at: http://www.reuters.com/ article/2014/04/04/amgen-melanoma-idCNL4N0MW3AL20140404.
-
(2014)
Reuters
-
-
-
55
-
-
84905008082
-
Primary analysis of a phase 1b multicenter trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (IPI) in previously untreated, unresected stage IIIB-IV melanoma
-
meeting abstracts, Available at
-
Puzanov I, Milhem MM, Andtbacka RHI, et al. Primary analysis of a phase 1b multicenter trial to evaluate safety and efficacy of talimogene laherparepvec (T-VEC) and ipilimumab (IPI) in previously untreated, unresected stage IIIB-IV melanoma. J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9029. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/9029?sid=6eb4029c-0ebb-49ef-b2bd-a1d959f2d484.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Puzanov, I.1
Milhem, M.M.2
Andtbacka, R.H.I.3
-
56
-
-
0024166189
-
Use of tumorinfiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report
-
Rosenberg SA, Packard BS, Aebersold PM, et al. Use of tumorinfiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report. N Engl J Med, 1988,319:1676-1680.
-
(1988)
N Engl J Med
, vol.319
, pp. 1676-1680
-
-
Rosenberg, S.A.1
Packard, B.S.2
Aebersold, P.M.3
-
57
-
-
0023907493
-
Interleukin-2: Inception, impact, and implications
-
Smith KA. Interleukin-2: inception, impact, and implications. Science, 1988,240:1169-1176.
-
(1988)
Science
, vol.240
, pp. 1169-1176
-
-
Smith, K.A.1
-
58
-
-
84871462134
-
A phase I doseescalation study of the immunocytokine EMD 521873 (selectikine) in patients with advanced solid tumours
-
Gillessen S, Gnad-Vogt US, Gallerani E, et al. A phase I doseescalation study of the immunocytokine EMD 521873 (selectikine) in patients with advanced solid tumours. Eur J Cancer, 2013,49:35-44.
-
(2013)
Eur J Cancer
, vol.49
, pp. 35-44
-
-
Gillessen, S.1
Gnad-Vogt, U.S.2
Gallerani, E.3
-
59
-
-
84871887425
-
T-cell activation by treatment of cancer patients with EMD521873 (Selectikine), an IL-2/ anti-DNA fusion protein
-
Laurent J, Touvrey C, Gillessen S, et al. T-cell activation by treatment of cancer patients with EMD521873 (Selectikine), an IL-2/ anti-DNA fusion protein. J Transl Med, 2013,11:5.
-
(2013)
J Transl Med
, vol.11
, pp. 5
-
-
Laurent, J.1
Touvrey, C.2
Gillessen, S.3
-
60
-
-
84907498829
-
Targeted modified IL-2 (NHS-IL2, MSB0010445) combined with stereotactic body radiation in advanced melanoma patients after progression on ipilimumab: Assessment of safety, clinical, and biologic activity in a phase 2a study
-
meeting abstracts, Available at
-
Kaufman HL, Mehnert JM, Cuillerot J, et al. Targeted modified IL-2 (NHS-IL2, MSB0010445) combined with stereotactic body radiation in advanced melanoma patients after progression on ipilimumab: assessment of safety, clinical, and biologic activity in a phase 2a study. J Clin Oncol (meeting abstracts), 2014,32:15_suppl TPS9107. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/TPS9107?sid=c346407f-74a5-4150-9274-ebf40a25dd45.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Kaufman, H.L.1
Mehnert, J.M.2
Cuillerot, J.3
-
61
-
-
84907498828
-
Tumor response and patient survival after intralesional therapy with low-dose GM-CSF and IL-2 in metastatic and primary cutaneous melanoma: An exploratory study
-
meeting abstracts, Available at
-
Elias EG, Sharma BK. Tumor response and patient survival after intralesional therapy with low-dose GM-CSF and IL-2 in metastatic and primary cutaneous melanoma: an exploratory study. J Clin Oncol (meeting abstracts), 2014,32:15_supple 20002. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/e20002?sid=bec1137b-9959-407b-a9ec-b0e4ca0951e5.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Elias, E.G.1
Sharma, B.K.2
-
62
-
-
84864040339
-
Should highdose interleukin-2 still be the preferred treatment for patients with metastatic melanoma?
-
Dillman RO, Barth NM, VanderMolen LA, et al. Should highdose interleukin-2 still be the preferred treatment for patients with metastatic melanoma? Cancer Biother Radiopharm, 2012,27:337-343.
-
(2012)
Cancer Biother Radiopharm
, vol.27
, pp. 337-343
-
-
Dillman, R.O.1
Barth, N.M.2
Vandermolen, L.A.3
-
63
-
-
16644401873
-
Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma
-
McDermott DF, Regan MM, Clark JI, et al. Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma. J Clin Oncol, 2005,23:133-141.
-
(2005)
J Clin Oncol
, vol.23
, pp. 133-141
-
-
McDermott, D.F.1
Regan, M.M.2
Clark, J.I.3
-
64
-
-
74949143594
-
Final version of 2009 AJCC melanoma staging and classification
-
Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol, 2009,27:6199-6206.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6199-6206
-
-
Balch, C.M.1
Gershenwald, J.E.2
Soong, S.J.3
-
65
-
-
84907498827
-
Systemic antitumor effect and clinical response in a phase 2 trial of intratumoral electroporation of plasmid interleukin-12 in patients with advanced melanoma
-
meeting abstracts, Available at
-
Daud A, Algazi AP, Ashworth MT, et al. Systemic antitumor effect and clinical response in a phase 2 trial of intratumoral electroporation of plasmid interleukin-12 in patients with advanced melanoma. J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9025. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/9025?sid=784dd2db-982d-4632-9123-67e81b7a2e55.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Daud, A.1
Algazi, A.P.2
Ashworth, M.T.3
-
66
-
-
84893169166
-
Type I interferons: Key players in normal skin and select cutaneous malignancies
-
Ismail A, Yusuf N. Type I interferons: key players in normal skin and select cutaneous malignancies. Dermatol Res Pract, 2014,2014:847545.
-
(2014)
Dermatol Res Pract
, pp. 2014
-
-
Ismail, A.1
Yusuf, N.2
-
67
-
-
84907498826
-
Predictive importance of ulceration on the efficacy of adjuvant interferon-a (IFN): An individual patient data (IPD) meta-analysis of 15 randomized trials in more than 7,500 melanoma patients (pts)
-
meeting abstracts, Available at
-
Suciu S, Ives N, Eggermont AM, et al. Predictive importance of ulceration on the efficacy of adjuvant interferon-a (IFN): an individual patient data (IPD) meta-analysis of 15 randomized trials in more than 7,500 melanoma patients (pts). J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9067. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_ suppl/9067?sid=07e3681f-40a6-4e23-94c7-cf78f2135b96.
-
(2014)
J Clin Oncol
, vol.32
, Issue.15
-
-
Suciu, S.1
Ives, N.2
Eggermont, A.M.3
-
68
-
-
79955561959
-
Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients
-
Simons DL, Lee G, Kirkwood JM, et al. Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients. J Transl Med, 2011,9:52.
-
(2011)
J Transl Med
, vol.9
, pp. 52
-
-
Simons, D.L.1
Lee, G.2
Kirkwood, J.M.3
-
69
-
-
84868113790
-
U.S. Food and Drug Administration Approval: Peginterferon-alfa-2b for the adjuvant treatment of patients with melanoma
-
Herndon TM, Demko SG, Jiang X, et al. U.S. Food and Drug Administration Approval: peginterferon-alfa-2b for the adjuvant treatment of patients with melanoma. Oncologist, 2012,17:1323-1328.
-
(2012)
Oncologist
, vol.17
, pp. 1323-1328
-
-
Herndon, T.M.1
Demko, S.G.2
Jiang, X.3
-
70
-
-
84869212118
-
Long-term results of the randomized phase III trial EORTC18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma
-
Eggermont AM, Suciu S, Testori A, et al. Long-term results of the randomized phase III trial EORTC18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma. J Clin Oncol, 2012,30:3810-3818.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3810-3818
-
-
Eggermont, A.M.1
Suciu, S.2
Testori, A.3
-
71
-
-
84890288887
-
ECOG phase II trial of graded-dose peginterferon alpha-2b in patients with metastatic melanoma overexpressing basic fibroblast growth factor (E2602)
-
Go RS, Lee SJ, Shin D, et al. ECOG phase II trial of graded-dose peginterferon alpha-2b in patients with metastatic melanoma overexpressing basic fibroblast growth factor (E2602). Clin Cancer Res, 2013,19:6597-6604.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 6597-6604
-
-
Go, R.S.1
Lee, S.J.2
Shin, D.3
-
72
-
-
84907498825
-
Adjuvant therapy with pegylated interferon alfa-2a (PEG-IFN) versus low-dose interferon alfa-2a (IFN) in patients with malignant melanoma in stages IIa (T3a): IIIb (AJCC 2002)—DeCOG-trialJ Clin Oncol
-
meeting abstracts, Available at
-
Eigentler TK, Gutzmer R, Hauschild A, et al. Adjuvant therapy with pegylated interferon alfa-2a (PEG-IFN) versus low-dose interferon alfa-2a (IFN) in patients with malignant melanoma in stages IIa (T3a): IIIb (AJCC 2002)—DeCOG-trial. J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9071. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/9071?sid=c3ac38d9-0279-4d16-98f8-66fc1f410135.
-
(2014)
, vol.32
, Issue.15
-
-
Eigentler, T.K.1
Gutzmer, R.2
Hauschild, A.3
-
73
-
-
84907498824
-
A phase IB study of ipilimumab with peginterferon alfa-2b for patients with unresectable stages IIIB/C/IV melanomaJ Clin Oncol
-
meeting abstracts, Available at
-
Kudchadkar RR, Gibney GT, Dorman D, et al. A phase IB study of ipilimumab with peginterferon alfa-2b for patients with unresectable stages IIIB/C/IV melanoma. J Clin Oncol (meeting abstracts), 2014,32:15_suppl 9098. Available at: http://meeting.ascopubs.org/cgi/content/abstract/32/15_suppl/9098?sid=386f4af7-be4d-4279-930c-ec01070b1e78.
-
(2014)
, vol.32
, Issue.15
-
-
Kudchadkar, R.R.1
Gibney, G.T.2
Dorman, D.3
-
74
-
-
84880778718
-
Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors
-
Stones CJ, Kim JE, Joseph WR, et al. Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors. Front Genet, 2013,4:66.
-
(2013)
Front Genet
, vol.4
, pp. 66
-
-
Stones, C.J.1
Kim, J.E.2
Joseph, W.R.3
-
75
-
-
84863673204
-
Improved survival with MEK inhibition in BRAF-mutated melanoma
-
Flaherty KT, Robert C, Hersey P, et al. Improved survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med, 2012,367:107-114.
-
(2012)
N Engl J Med
, vol.367
, pp. 107-114
-
-
Flaherty, K.T.1
Robert, C.2
Hersey, P.3
-
76
-
-
84879496934
-
Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma
-
Trunzer K, Pavlick AC, Schuchter L, et al. Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma. J Clin Oncol, 2013,31:1767-1774.
-
(2013)
J Clin Oncol
, vol.31
, pp. 1767-1774
-
-
Trunzer, K.1
Pavlick, A.C.2
Schuchter, L.3
-
77
-
-
84873399856
-
Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells
-
Beck D, Niessner H, Smalley KS, et al. Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells. Sci Signal, 2013,6:ra7.
-
(2013)
Sci Signal
, vol.6
, pp. ra7
-
-
Beck, D.1
Niessner, H.2
Smalley, K.S.3
-
78
-
-
84864285704
-
Dabrafenib in BRAFmutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
-
Hauschild A, Grob JJ, Demidov LV, et al. Dabrafenib in BRAFmutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet, 2012,380:358-365.
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
-
79
-
-
84874777853
-
Phase II study of the MEK1/ MEK2 inhibitor trametinib in patients with metastatic braf-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor
-
Kim KB, Kefford R, Pavlick AC, et al. Phase II study of the MEK1/ MEK2 inhibitor trametinib in patients with metastatic braf-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor. J Clin Oncol, 2013,31:482-489.
-
(2013)
J Clin Oncol
, vol.31
, pp. 482-489
-
-
Kim, K.B.1
Kefford, R.2
Pavlick, A.C.3
-
80
-
-
84868224906
-
Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
-
Flaherty KT, Infante JR, Daud A, et al. Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med, 2012,367:1694-1703.
-
(2012)
N Engl J Med
, vol.367
, pp. 1694-1703
-
-
Flaherty, K.T.1
Infante, J.R.2
Daud, A.3
-
81
-
-
84894183166
-
Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib
-
Acquaviva J, Smith DL, Jimenez JP, et al. Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib. Mol Cancer Ther, 2014,13:353-363.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 353-363
-
-
Acquaviva, J.1
Smith, D.L.2
Jimenez, J.P.3
-
82
-
-
78649853358
-
Antisense treatment in human prostate cancer and melanoma
-
Di Cresce C, Koropatnick J. Antisense treatment in human prostate cancer and melanoma. Curr Cancer Drug Targets, 2010,10:555-565.
-
(2010)
Curr Cancer Drug Targets
, vol.10
, pp. 555-565
-
-
Di Cresce, C.1
Koropatnick, J.2
-
83
-
-
84872287502
-
Oblimersen in combination with temozolomide and albumin-bound paclitaxel in patients with advanced melanoma: A phase I trial
-
Ott PA, Chang J, Madden K, et al. Oblimersen in combination with temozolomide and albumin-bound paclitaxel in patients with advanced melanoma: a phase I trial. Cancer Chemother Pharmacol, 2013,71:183-191.
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, pp. 183-191
-
-
Ott, P.A.1
Chang, J.2
Madden, K.3
-
84
-
-
23844455213
-
Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: Roles of anoikis
-
Aixinjueluo W, Furukawa K, Zhang Q, et al. Mechanisms for the apoptosis of small cell lung cancer cells induced by anti-GD2 monoclonal antibodies: roles of anoikis. J Biol Chem, 2005,280:29828-29836.
-
(2005)
J Biol Chem
, vol.280
, pp. 29828-29836
-
-
Aixinjueluo, W.1
Furukawa, K.2
Zhang, Q.3
-
85
-
-
84865115651
-
Trifunctional bispecific antibodies induce tumor-specific T cells and elicit a vaccination effect
-
Eissler N, Ruf P, Mysliwietz J, et al. Trifunctional bispecific antibodies induce tumor-specific T cells and elicit a vaccination effect. Cancer Res, 2012,72:3958-3966.
-
(2012)
Cancer Res
, vol.72
, pp. 3958-3966
-
-
Eissler, N.1
Ruf, P.2
Mysliwietz, J.3
|