메뉴 건너뛰기




Volumn 63, Issue 10, 2014, Pages 3230-3241

Sleep fragmentation during late gestation induces metabolic perturbations and epigenetic changes in adiponectin gene expression in male adult offspring mice

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; ADIPONECTIN; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; HISTONE ACETYLTRANSFERASE; MICRORNA; TRIACYLGLYCEROL;

EID: 84907483801     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0202     Document Type: Article
Times cited : (41)

References (54)
  • 2
    • 84894059202 scopus 로고    scopus 로고
    • Body mass index categories and mortality risk in US adults: The effect of overweight and obesity on advancing death
    • Borrell LN, Samuel L. Body mass index categories and mortality risk in US adults: the effect of overweight and obesity on advancing death. Am J Public Health 2014;104:512-519
    • (2014) Am J Public Health , vol.104 , pp. 512-519
    • Borrell, L.N.1    Samuel, L.2
  • 3
    • 11844250659 scopus 로고    scopus 로고
    • The developmental origins of adult disease
    • Barker DJ. The developmental origins of adult disease. J Am Coll Nutr 2004; 23(Suppl.):588S-595S
    • (2004) J Am Coll Nutr , vol.23 , pp. 588S-595S
    • Barker, D.J.1
  • 4
    • 34247168615 scopus 로고    scopus 로고
    • The origins of the developmental origins theory
    • Barker DJ. The origins of the developmental origins theory. J Intern Med 2007;261:412-417
    • (2007) J Intern Med , vol.261 , pp. 412-417
    • Barker, D.J.1
  • 5
    • 15544369982 scopus 로고    scopus 로고
    • Developmental origins of the metabolic syndrome: Prediction, plasticity, and programming
    • McMillen IC, Robinson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 2005;85:571-633
    • (2005) Physiol Rev , vol.85 , pp. 571-633
    • McMillen, I.C.1    Robinson, J.S.2
  • 7
    • 43049127871 scopus 로고    scopus 로고
    • Developmental origins of obesity and the metabolic syndrome: The role of maternal obesity
    • Armitage JA, Poston L, Taylor PD. Developmental origins of obesity and the metabolic syndrome: the role of maternal obesity. Front Horm Res 2008;36: 73-84
    • (2008) Front Horm Res , vol.36 , pp. 73-84
    • Armitage, J.A.1    Poston, L.2    Taylor, P.D.3
  • 8
    • 84879122864 scopus 로고    scopus 로고
    • Maternal high-fat diets cause insulin resistance through inflammatory changes in fetal adipose tissue
    • Murabayashi N, Sugiyama T, Zhang L, et al. Maternal high-fat diets cause insulin resistance through inflammatory changes in fetal adipose tissue. Eur J Obstet Gynecol Reprod Biol 2013;169:39-44
    • (2013) Eur J Obstet Gynecol Reprod Biol , vol.169 , pp. 39-44
    • Murabayashi, N.1    Sugiyama, T.2    Zhang, L.3
  • 9
    • 70350041294 scopus 로고    scopus 로고
    • Distinguishing pathological from constitutional small for gestational age births in population-based studies
    • Ananth CV, Vintzileos AM. Distinguishing pathological from constitutional small for gestational age births in population-based studies. Early Hum Dev 2009;85:653-658
    • (2009) Early Hum Dev , vol.85 , pp. 653-658
    • Ananth, C.V.1    Vintzileos, A.M.2
  • 10
    • 67349154088 scopus 로고    scopus 로고
    • Endocrine disrupters as obesogens
    • Grün F, Blumberg B. Endocrine disrupters as obesogens. Mol Cell Endocrinol 2009;304:19-29
    • (2009) Mol Cell Endocrinol , vol.304 , pp. 19-29
    • Grün, F.1    Blumberg, B.2
  • 11
    • 67449102553 scopus 로고    scopus 로고
    • Intergenerational programming of impaired nephrogenesis and hypertension in rats following maternal protein restriction during pregnancy
    • Harrison M, Langley-Evans SC. Intergenerational programming of impaired nephrogenesis and hypertension in rats following maternal protein restriction during pregnancy. Br J Nutr 2009;101:1020-1030
    • (2009) Br J Nutr , vol.101 , pp. 1020-1030
    • Harrison, M.1    Langley-Evans, S.C.2
  • 12
    • 84882267060 scopus 로고    scopus 로고
    • Sleep duration and disorders in pregnancy: Implications for glucose metabolism and pregnancy outcomes
    • O'Keeffe M, St-Onge MP. Sleep duration and disorders in pregnancy: implications for glucose metabolism and pregnancy outcomes. Int J Obes (Lond) 2013;37:765-770
    • (2013) Int J Obes (Lond) , vol.37 , pp. 765-770
    • O'Keeffe, M.1    St-Onge, M.P.2
  • 14
    • 84887079807 scopus 로고    scopus 로고
    • Snoring during pregnancy and delivery outcomes: A cohort study
    • O'Brien LM, Bullough AS, Owusu JT, et al. Snoring during pregnancy and delivery outcomes: a cohort study. Sleep 2013;36:1625-1632
    • (2013) Sleep , vol.36 , pp. 1625-1632
    • O'Brien, L.M.1    Bullough, A.S.2    Owusu, J.T.3
  • 15
    • 16644381688 scopus 로고    scopus 로고
    • Sleep disorders during pregnancy
    • Pien GW, Schwab RJ. Sleep disorders during pregnancy. Sleep 2004;27: 1405-1417
    • (2004) Sleep , vol.27 , pp. 1405-1417
    • Pien, G.W.1    Schwab, R.J.2
  • 16
    • 84895076679 scopus 로고    scopus 로고
    • The relationship and potential mechanistic pathways between sleep disturbances and maternal hyperglycemia
    • Izci-Balserak B, Pien GW. The relationship and potential mechanistic pathways between sleep disturbances and maternal hyperglycemia. Curr Diab Rep 2014;14:459
    • (2014) Curr Diab Rep , vol.14 , pp. 459
    • Izci-Balserak, B.1    Pien, G.W.2
  • 17
    • 34347351228 scopus 로고    scopus 로고
    • Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the framingham heart study
    • Fox CS, Massaro JM, Hoffmann U, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation 2007;116:39-48
    • (2007) Circulation , vol.116 , pp. 39-48
    • Fox, C.S.1    Massaro, J.M.2    Hoffmann, U.3
  • 19
    • 27744597211 scopus 로고    scopus 로고
    • Adiponectin represses gluconeogenesis independent of insulin in hepatocytes
    • Zhou H, Song X, Briggs M, et al. Adiponectin represses gluconeogenesis independent of insulin in hepatocytes. Biochem Biophys Res Commun 2005;338: 793-799
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 793-799
    • Zhou, H.1    Song, X.2    Briggs, M.3
  • 20
    • 33646346627 scopus 로고    scopus 로고
    • Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists
    • Nawrocki AR, Rajala MW, Tomas E, et al. Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists. J Biol Chem 2006;281:2654-2660
    • (2006) J Biol Chem , vol.281 , pp. 2654-2660
    • Nawrocki, A.R.1    Rajala, M.W.2    Tomas, E.3
  • 21
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev 2005;26:439-451
    • (2005) Endocr Rev , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 22
    • 82555168382 scopus 로고    scopus 로고
    • Sleep fragmentation induces cognitive deficits via nicotinamide adenine dinucleotide phosphate oxidase-dependent pathways in mouse
    • Nair D, Zhang SX, Ramesh V, et al. Sleep fragmentation induces cognitive deficits via nicotinamide adenine dinucleotide phosphate oxidase-dependent pathways in mouse. Am J Respir Crit Care Med 2011;184:1305-1312
    • (2011) Am J Respir Crit Care Med , vol.184 , pp. 1305-1312
    • Nair, D.1    Zhang, S.X.2    Ramesh, V.3
  • 23
    • 84860812158 scopus 로고    scopus 로고
    • Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor - A pathway
    • Ramesh V, Nair D, Zhang SX, et al. Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-a pathway. J Neuroinflammation 2012;9:91
    • (2012) J Neuroinflammation , vol.9 , pp. 91
    • Ramesh, V.1    Nair, D.2    Zhang, S.X.3
  • 24
    • 84867273790 scopus 로고    scopus 로고
    • Metabolic effects of intermittent hypoxia in mice: Steady versus high-frequency applied hypoxia daily during the rest period
    • Carreras A, Kayali F, Zhang J, Hirotsu C, Wang Y, Gozal D. Metabolic effects of intermittent hypoxia in mice: steady versus high-frequency applied hypoxia daily during the rest period. Am J Physiol Regul Integr Comp Physiol 2012;303: R700-R709
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.303 , pp. R700-R709
    • Carreras, A.1    Kayali, F.2    Zhang, J.3    Hirotsu, C.4    Wang, Y.5    Gozal, D.6
  • 25
    • 70350453755 scopus 로고    scopus 로고
    • The human insulin gene is part of a large open chromatin domain specific for human islets
    • Mutskov V, Felsenfeld G. The human insulin gene is part of a large open chromatin domain specific for human islets. Proc Natl Acad Sci U S A 2009;106: 17419-17424
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 17419-17424
    • Mutskov, V.1    Felsenfeld, G.2
  • 26
    • 0037098039 scopus 로고    scopus 로고
    • The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation
    • Mutskov VJ, Farrell CM, Wade PA, Wolffe AP, Felsenfeld G. The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. Genes Dev 2002;16:1540-1554
    • (2002) Genes Dev , vol.16 , pp. 1540-1554
    • Mutskov, V.J.1    Farrell, C.M.2    Wade, P.A.3    Wolffe, A.P.4    Felsenfeld, G.5
  • 27
    • 0842307061 scopus 로고    scopus 로고
    • Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9
    • Mutskov V, Felsenfeld G. Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. EMBO J 2004;23:138-149
    • (2004) EMBO J , vol.23 , pp. 138-149
    • Mutskov, V.1    Felsenfeld, G.2
  • 28
    • 52949137872 scopus 로고    scopus 로고
    • Regulation of expression of the mouse adiponectin gene by the C/EBP family via a novel enhancer region
    • Koshiishi C, Park HM, Uchiyama H, Tanaka Y. Regulation of expression of the mouse adiponectin gene by the C/EBP family via a novel enhancer region. Gene 2008;424:141-146
    • (2008) Gene , vol.424 , pp. 141-146
    • Koshiishi, C.1    Park, H.M.2    Uchiyama, H.3    Tanaka, Y.4
  • 29
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Suppl.
    • Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003;33 (Suppl.):245-254
    • (2003) Nat Genet , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 30
    • 82955207588 scopus 로고    scopus 로고
    • Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
    • Wu H, Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev 2011;25:2436-2452
    • (2011) Genes Dev , vol.25 , pp. 2436-2452
    • Wu, H.1    Zhang, Y.2
  • 31
    • 79956302047 scopus 로고    scopus 로고
    • TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
    • Williams K, Christensen J, Pedersen MT, et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 2011;473:343-348
    • (2011) Nature , vol.473 , pp. 343-348
    • Williams, K.1    Christensen, J.2    Pedersen, M.T.3
  • 32
    • 77951552945 scopus 로고    scopus 로고
    • Study of caveolin-1 gene expression in whole adipose tissue and its subtractions and during differentiation of human adipocytes
    • Fernández-Real JM, Catalán V, Moreno-Navarrete JM, et al. Study of caveolin-1 gene expression in whole adipose tissue and its subtractions and during differentiation of human adipocytes. Nutr Metab (Lond) 2010;7:20
    • (2010) Nutr Metab (Lond) , vol.7 , pp. 20
    • Fernández-Real, J.M.1    Catalán, V.2    Moreno-Navarrete, J.M.3
  • 33
    • 79959845414 scopus 로고    scopus 로고
    • MicroRNAs 103 and 107 regulate insulin sensitivity
    • Trajkovski M, Hausser J, Soutschek J, et al. MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 2011;474:649-653
    • (2011) Nature , vol.474 , pp. 649-653
    • Trajkovski, M.1    Hausser, J.2    Soutschek, J.3
  • 34
    • 33847367675 scopus 로고    scopus 로고
    • Non-genomic transgenerational inheritance of disease risk
    • Gluckman PD, Hanson MA, Beedle AS. Non-genomic transgenerational inheritance of disease risk. Bioessays 2007;29:145-154
    • (2007) Bioessays , vol.29 , pp. 145-154
    • Gluckman, P.D.1    Hanson, M.A.2    Beedle, A.S.3
  • 35
    • 84887839654 scopus 로고    scopus 로고
    • Effects of late gestational high-fat diet on body weight, metabolic regulation and adipokine expression in offspring
    • Khalyfa A, Carreras A, Hakim F, Cunningham JM, Wang Y, Gozal D. Effects of late gestational high-fat diet on body weight, metabolic regulation and adipokine expression in offspring. Int J Obes (Lond)2013;37:1481 -1489
    • (2013) Int J Obes (Lond) , vol.37 , pp. 1481-1489
    • Khalyfa, A.1    Carreras, A.2    Hakim, F.3    Cunningham, J.M.4    Wang, Y.5    Gozal, D.6
  • 36
    • 77953724327 scopus 로고    scopus 로고
    • Perinatal environment and its influences on metabolic programming of offspring
    • Tamashiro KL, Moran TH. Perinatal environment and its influences on metabolic programming of offspring. Physiol Behav 2010;100:560-566
    • (2010) Physiol Behav , vol.100 , pp. 560-566
    • Tamashiro, K.L.1    Moran, T.H.2
  • 37
    • 0242288690 scopus 로고    scopus 로고
    • Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: Cross-sectional and interventional studies
    • Gavrila A, Chan JL, Yiannakouris N, et al. Serum adiponectin levels are inversely associated with overall and central fat distribution but are not directly regulated by acute fasting or leptin administration in humans: cross-sectional and interventional studies. J Clin Endocrinol Metab 2003;88:4823-4831
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4823-4831
    • Gavrila, A.1    Chan, J.L.2    Yiannakouris, N.3
  • 38
    • 0036034966 scopus 로고    scopus 로고
    • Identification of regulatory elements in the human adipose most abundant gene transcript-1 (apM-1) promoter: Role of SP1/SP3 and TNF-alpha as regulatory pathways
    • Barth N, Langmann T, Schölmerich J, Schmitz G, Schäffler A. Identification of regulatory elements in the human adipose most abundant gene transcript-1 (apM-1) promoter: role of SP1/SP3 and TNF-alpha as regulatory pathways. Diabetologia 2002;45:1425-1433
    • (2002) Diabetologia , vol.45 , pp. 1425-1433
    • Barth, N.1    Langmann, T.2    Schölmerich, J.3    Schmitz, G.4    Schäffler, A.5
  • 39
    • 84861313012 scopus 로고    scopus 로고
    • Effects of a high-fat diet exposure in utero on the metabolic syndrome-like phenomenon in mouse offspring through epigenetic changes in adipocytokine gene expression
    • Masuyama H, Hiramatsu Y. Effects of a high-fat diet exposure in utero on the metabolic syndrome-like phenomenon in mouse offspring through epigenetic changes in adipocytokine gene expression. Endocrinology 2012;153: 2823-2830
    • (2012) Endocrinology , vol.153 , pp. 2823-2830
    • Masuyama, H.1    Hiramatsu, Y.2
  • 40
    • 68049095260 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome in histone demethylase JHDM2a-deflcient mice
    • Inagaki T, Tachibana M, Magoori K, et al. Obesity and metabolic syndrome in histone demethylase JHDM2a-deflcient mice. Genes Cells 2009;14: 991-1001
    • (2009) Genes Cells , vol.14 , pp. 991-1001
    • Inagaki, T.1    Tachibana, M.2    Magoori, K.3
  • 41
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • Tateishi K, Okada Y, Kallin EM, Zhang Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 2009;458:757-761
    • (2009) Nature , vol.458 , pp. 757-761
    • Tateishi, K.1    Okada, Y.2    Kallin, E.M.3    Zhang, Y.4
  • 42
    • 33745198218 scopus 로고    scopus 로고
    • Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes
    • Musri MM, Corominola H, Casamitjana R, Gomis R, Párrizas M. Histone H3 lysine 4 dimethylation signals the transcriptional competence of the adiponectin promoter in preadipocytes. J Biol Chem 2006;281:17180-17188
    • (2006) J Biol Chem , vol.281 , pp. 17180-17188
    • Musri, M.M.1    Corominola, H.2    Casamitjana, R.3    Gomis, R.4    Párrizas, M.5
  • 43
    • 67650720957 scopus 로고    scopus 로고
    • Modifications of histone H3 at lysine 9 on the adiponectin gene in 3T3-L1 adipocytes
    • Sakurai N, Mochizuki K, Goda T. Modifications of histone H3 at lysine 9 on the adiponectin gene in 3T3-L1 adipocytes. J Nutr Sci Vitaminol (Tokyo) 2009;55: 131-138
    • (2009) J Nutr Sci Vitaminol (Tokyo) , vol.55 , pp. 131-138
    • Sakurai, N.1    Mochizuki, K.2    Goda, T.3
  • 44
    • 77951497959 scopus 로고    scopus 로고
    • Early nutrition and epigenetic programming: Chasing shadows
    • Attig L, Gabory A, Junien C. Early nutrition and epigenetic programming: chasing shadows. Curr Opin Clin Nutr Metab Care 2010;13:284-293
    • (2010) Curr Opin Clin Nutr Metab Care , vol.13 , pp. 284-293
    • Attig, L.1    Gabory, A.2    Junien, C.3
  • 45
    • 70449432882 scopus 로고    scopus 로고
    • MicroRNA: MIR-ly regulators of DNMT?
    • Griffiths EA, Gore SD. MicroRNA: mIR-ly regulators of DNMT? Blood 2009; 113:6269-6270
    • (2009) Blood , vol.113 , pp. 6269-6270
    • Griffiths, E.A.1    Gore, S.D.2
  • 46
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999;99:247-257
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 47
    • 75749127447 scopus 로고    scopus 로고
    • Increased expression of DNA methyltransferase 3a in obese adipose tissue: Studies with transgenic mice
    • Kamei Y, Suganami T, Ehara T, et al. Increased expression of DNA methyltransferase 3a in obese adipose tissue: studies with transgenic mice. Obesity (Silver Spring) 2010;18:314-321
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 314-321
    • Kamei, Y.1    Suganami, T.2    Ehara, T.3
  • 48
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010;466:1129-1133
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 49
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani M, Koh KP, Shen Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009;324:930-935
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3
  • 50
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S, Shen L, Dai Q, et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011;333:1300-1303
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3
  • 51
    • 79960175448 scopus 로고    scopus 로고
    • MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis
    • Hulsmans M, De Keyzer D, Holvoet P. MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis. FASEB J 2011;25: 2515-2527
    • (2011) FASEB J , vol.25 , pp. 2515-2527
    • Hulsmans, M.1    De Keyzer, D.2    Holvoet, P.3
  • 52
    • 34250755430 scopus 로고    scopus 로고
    • Role of caveolins in body weight and insulin resistance regulation
    • Frühbeck G, López M, Diéguez C. Role of caveolins in body weight and insulin resistance regulation. Trends Endocrinol Metab 2007;18:177-182
    • (2007) Trends Endocrinol Metab , vol.18 , pp. 177-182
    • Frühbeck, G.1    López, M.2    Diéguez, C.3
  • 53
    • 84895807775 scopus 로고    scopus 로고
    • Chronic sleep fragmentation promotes obesity in young adult mice
    • Wang Y, Carreras A, Lee SH, et al. Chronic sleep fragmentation promotes obesity in young adult mice. Obesity (Silver Spring) 2014;22:758-762
    • (2014) Obesity (Silver Spring) , vol.22 , pp. 758-762
    • Wang, Y.1    Carreras, A.2    Lee, S.H.3
  • 54
    • 67349190274 scopus 로고    scopus 로고
    • Sexual dimorphism in environmental epigenetic programming
    • Gabory A, Attig L, Junien C. Sexual dimorphism in environmental epigenetic programming. Mol Cell Endocrinol 2009;304:8-18
    • (2009) Mol Cell Endocrinol , vol.304 , pp. 8-18
    • Gabory, A.1    Attig, L.2    Junien, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.