Mutation-free baby born from a mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome carrier after blastocyst trophectoderm preimplantation genetic diagnosis

Mitochondrion

Volumn 18, Issue , 2014, Pages 12-17

  Heindryckx, Björn ^a   Neupane, Jitesh ^a   Vandewoestyne, Mado ^b   Christodoulou, Christodoulos ^a   Jackers, Yens ^b   Gerris, Jan ^a   Van den Abbeel, Etienne ^a   Van Coster, Rudy ^a   Deforce, Dieter ^b   De Sutter, Petra ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Blastocyst; Heteroplasmy; Mitochondrial DNA (mtDNA); Preimplantation genetic diagnosis (PGD); Trophectoderm biopsy

Indexed keywords

CHORIONIC GONADOTROPIN; DNA FRAGMENT; HUMAN MENOPAUSAL GONADOTROPIN; LEUCINE; MITOCHONDRIAL DNA; TRANSFER RNA; TRIPTORELIN;

ADULT; ARTICLE; BIOPSY TECHNIQUE; BLASTOCYST; BLOOD CELL; CYTOPLASM; DNA FRAGMENTATION; ECTODERM; EMBRYO; EMBRYO TRANSFER; FEMALE; HATCHING; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACYTOPLASMIC SPERM INJECTION; MALE; MELAS SYNDROME; MITOCHONDRIAL GENOME; MUTATION LOAD; MUTATION RATE; NEWBORN; OVARY HYPERSTIMULATION; POINT MUTATION; PREIMPLANTATION GENETIC DIAGNOSIS; PRENATAL DIAGNOSIS; TROPHECTODERM; TROPHECTODERM BIOPSY; BIOPSY; CASE REPORT; PREGNANCY; PREGNANCY COMPLICATION;

ADULT; BIOPSY; EMBRYO TRANSFER; FEMALE; HUMANS; INFANT, NEWBORN; MALE; MELAS SYNDROME; PREGNANCY; PREGNANCY COMPLICATIONS; PREIMPLANTATION DIAGNOSIS;

EID: 84907471711     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2014.08.005     Document Type: Article

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