Inhibition of DNA topoisomerase ii selectively reduces the threat of tumorigenicity following induced pluripotent stem cell-based myocardial therapy

Stem Cells and Development

Volumn 23, Issue 19, 2014, Pages 2274-2282

  Wyles, Saranya P ^a   Yamada, Satsuki ^a   Oommen, Saji ^a   Maleszewski, Joseph J ^a   Beraldi, Rosanna ^a   Martinez Fernandez, Almudena ^a   Terzic, Andre ^a,b   Nelson, Timothy J ^a,b  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); ETOPOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLUMINESCENCE; CARCINOGENICITY; CARDIAC STEM CELL; CELL DIFFERENTIATION; CELL POPULATION; CONTROLLED STUDY; EMBRYO; ENGRAFTMENT; ENZYME INHIBITION; HEART INFARCTION; HEART MUSCLE; IC50; IMMUNE DEFICIENCY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; STEM CELL TRANSPLANTATION; TERATOGENICITY; TERATOMA; THORACIC CAVITY; TUMOR VOLUME; ANIMAL; BIOLOGICAL THERAPY; CARCINOGENESIS; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; NUCLEAR REPROGRAMMING; PATHOLOGY; PHYSIOLOGY; PROCEDURES; REGENERATION; TRANSPLANTATION;

ANIMALS; CARCINOGENESIS; CELL DIFFERENTIATION; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; CELLULAR REPROGRAMMING; DNA TOPOISOMERASES, TYPE II; INDUCED PLURIPOTENT STEM CELLS; MICE; MYOCARDIUM; REGENERATION; STEM CELL TRANSPLANTATION;

EID: 84907434749     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2014.0259     Document Type: Article

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