Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: Improving the safety of iPS cell transplantation to myocardium

Cell Cycle

Volumn 13, Issue 5, 2014, Pages 762-771

  Zhang, Lan ^a,b   Pan, Yaohua ^a   Qin, Gangjian ^c   Chen, Lijuan ^d   Chatterjee, Tapan K ^b   Weintraub, Neal L ^b   Tang, Yaoliang ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

^d MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

iPS; Myocardial infarction; Nanog; PluriSin 1; Tumorigenicity

Indexed keywords

ACYL COENZYME A DESATURASE; DIMETHYL SULFOXIDE; MESSENGER RNA; OXYGENASE INHIBITOR; PLURIPOTENT CELL SPECIFIC INHIBITOR; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; NANOG PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER PREVENTION; CARCINOGENESIS; CARCINOGENICITY; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; ENGRAFTMENT; ENZYME INHIBITION; FIBROBLAST; HEART INFARCTION; HEART MUSCLE; HEART MUSCLE CELL; HEART TUMOR; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; STEM CELL CULTURE; STEM CELL TRANSPLANTATION; TERATOMA; TISSUE REGENERATION; TREATMENT DURATION; TUMOR GROWTH; ADVERSE EFFECTS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CELL TRANSPLANTATION; CYTOLOGY; GENETICS; METABOLISM; PATHOLOGY; TRANSPLANTATION;

ANIMALS; CARCINOGENESIS; CELL TRANSPLANTATION; CELLS, CULTURED; FIBROBLASTS; HOMEODOMAIN PROTEINS; INDUCED PLURIPOTENT STEM CELLS; MICE, INBRED C57BL; MYOCARDIUM; MYOCYTES, CARDIAC; STEAROYL-COA DESATURASE; STEM CELL TRANSPLANTATION;

EID: 84897996195     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.27677     Document Type: Article

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