Small nucleolar RNA 113-1 suppresses tumorigenesis in hepatocellular carcinoma

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Xu, Gang ^a   Yang, Fang ^b   Ding, Cui Ling ^a   Zhao, Lan Juan ^a   Ren, Hao ^a   Zhao, Ping ^a   Wang, Wen ^a   Qi, Zhong Tian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b FUZHOU GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; SMALL NUCLEOLAR RNA; SMALL NUCLEOLAR RNA 113-1, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENESIS; CELL FUNCTION; DOWN REGULATION; GENE; GENE EXPRESSION; HEPG2 CELL LINE; LIVER CELL CARCINOMA; METHYLATION; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; SMALL NUCLEOLAR RNA 113 1 GENE; TUMOR XENOGRAFT; ADULT; ANIMAL; CANCER TRANSPLANTATION; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HUMAN; LIVER TUMOR; MALE; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADULT; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; RNA, SMALL NUCLEOLAR;

EID: 84907420946     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-216     Document Type: Article

References (48)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011, 61:69-90. 10.3322/caac.20107, 21296855.
2. Aravalli RN, Steer CJ, Cressman EN. Molecular mechanisms of hepatocellular carcinoma. Hepatology 2008, 48:2047-2063. 10.1002/hep.22580, 19003900.
3. Huang S, He X. The role of microRNAs in liver cancer progression. Br J Cancer 2011, 104:235-240. 10.1038/sj.bjc.6606010, 3031886, 21102580.
4. Shi X, Sun M, Liu H, Yao Y, Song Y. Long non-coding RNAs: a new frontier in the study of human diseases. Cancer Lett 2013, 339:159-166. 10.1016/j.canlet.2013.06.013, 23791884.
5. Mannoor K, Liao J, Jiang F. Small nucleolar RNAs in cancer. Biochim Biophys Acta 1826, 2012:121-128.
6. Matera AG, Terns RM, Terns MP. Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs. Nat Rev Mol Cell Biol 2007, 8:209-220. 10.1038/nrm2124, 17318225.
7. Mei YP, Liao JP, Shen J, Yu L, Liu BL, Liu L, Li RY, Ji L, Dorsey SG, Jiang ZR, Katz RL, Wang JY, Jiang F. Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis. Oncogene 2012, 31:2794-2804. 10.1038/onc.2011.449, 21986946.
8. Liao J, Yu L, Mei Y, Guarnera M, Shen J, Li R, Liu Z, Jiang F. Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer. Mol Cancer 2010, 9:198. 10.1186/1476-4598-9-198, 2919450, 20663213.
9. Valleron W, Ysebaert L, Berquet L, Fataccioli V, Quelen C, Martin A, Parrens M, Lamant L, de Leval L, Gisselbrecht C, Gaulard P, Brousset P. Small nucleolar RNA expression profiling identifies potential prognostic markers in peripheral T-cell lymphoma. Blood 2012, 120:3997-4005. 10.1182/blood-2012-06-438135, 22990019.
10. Benetatos L, Hatzimichael E, Londin E, Vartholomatos G, Loher P, Rigoutsos I, Briasoulis E. The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis. Cell Mol Life Sci 2013, 70:795-814. 10.1007/s00018-012-1080-8, 22825660.
11. Song P, Gao J, Inagaki Y, Kokudo N, Hasegawa K, Sugawara Y, Tang W. Biomarkers: evaluation of screening for and early diagnosis of hepatocellular carcinoma in Japan and China. Liver Cancer 2013, 2:31-39. 10.1159/000346220, 3747538, 24159594.
12. Filmus J, Capurro M. Glypican-3: a marker and a therapeutic target in hepatocellular carcinoma. FEBS J 2013, 280:2471-2476. 10.1111/febs.12126, 23305321.
13. Miyasaka Y, Enomoto N, Nagayama K, Izumi N, Marumo F, Watanabe M, Sato C. Analysis of differentially expressed genes in human hepatocellular carcinoma using suppression subtractive hybridization. Br J Cancer 2001, 85:228-234. 10.1054/bjoc.2001.1901, 2364030, 11461082.
14. Heringlake S, Hofdmann M, Fiebeler A, Manns MP, Schmiegel W, Tannapfel A. Identification and expression analysis of the aldo-ketoreductase1-B10 gene in primary malignant liver tumours. J Hepatol 2010, 52:220-227. 10.1016/j.jhep.2009.11.005, 20036025.
15. Shang S, Plymoth A, Ge S, Feng Z, Rosen HR, Sangrajrang S, Hainaut P, Marrero JA, Beretta L. Identification of osteopontin as a novel marker for early hepatocellular carcinoma. Hepatology 2012, 55:483-490. 10.1002/hep.24703, 3914762, 21953299.
16. Muir K, Hazim A, He Y, Peyressatre M, Kim DY, Song X, Beretta L. Proteomic and lipidomic signatures of lipid metabolism in NASH-associated hepatocellular carcinoma. Cancer Res 2013, 73:4722-4731. 10.1158/0008-5472.CAN-12-3797, 3855016, 23749645.
17. Marshall A, Lukk M, Kutter C, Davies S, Alexander G, Odom DT. Global gene expression profiling reveals SPINK1 as a potential hepatocellular carcinoma marker. PLoS One 2013, 8:e59459. 10.1371/journal.pone.0059459, 3601070, 23527199.
18. Fu L, Dong SS, Xie YW, Tai LS, Chen L, Kong KL, Man K, Xie D, Li Y, Cheng Y, Tao Q, Guan XY. Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma. Hepatology 2010, 51:1624-1634. 10.1002/hep.23540, 20209601.
19. Bitton-Worms K, Pikarsky E, Aronheim A. The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice. Mol Cancer 2010, 9:54. 10.1186/1476-4598-9-54, 2841123, 20214788.
20. Tsunedomi R, Iizuka N, Hamamoto Y, Uchimura S, Miyamoto T, Tamesa T, Okada T, Takemoto N, Takashima M, Sakamoto K, Hamada K, Yamada-Okabe H, Oka M. Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma. Int J Oncol 2005, 27:661-667.
21. Wang B, Hsu SH, Frankel W, Ghoshal K, Jacob ST. Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. Hepatology 2012, 56:186-197. 10.1002/hep.25632, 3355233, 22318941.
22. Dong XY, Guo P, Boyd J, Sun X, Li Q, Zhou W, Dong JT. Implication of snoRNA U50 in human breast cancer. J Genet Genomics 2009, 36:447-454. 10.1016/S1673-8527(08)60134-4, 2854654, 19683667.
23. Dong XY, Rodriguez C, Guo P, Sun X, Talbot JT, Zhou W, Petros J, Li Q, Vessella RL, Kibel AS, Stevens VL, Calle EE, Dong JT. SnoRNA U50 is a candidate tumorsuppressor gene at 6q14.3 with a mutation associated with clinically significant prostate cancer. Hum Mol Genet 2008, 17:1031-1042. 2923223, 18202102.
24. Horsthemke B, Wagstaff J. Mechanisms of imprinting of the Prader-Willi/Angelman region. Am J Med Genet A 2008, 146:2041-2052.
25. Piao Z, Park C, Park JH, Kim H. Allelotype analysis of hepatocellular carcinoma. Int J Cancer 1998, 75:29-33. 10.1002/(SICI)1097-0215(19980105)75:1<29::AID-IJC5>3.0.CO;2-3, 9426686.
26. Bando T, Kato Y, Ihara Y, Yamagishi F, Tsukada K, Isobe M. Loss of heterozygosity of 14q32 in colorectal carcinoma. Cancer Genet Cytogenet 1999, 111:161-165. 10.1016/S0165-4608(98)00242-8, 10347556.
27. Croce CM. Genetic approaches to the study of the molecular basis of human cancer. Cancer Res 1991, 51:5015s-5018s.
28. Zhang X, Zhou YL, Mehta KR, Danila DC, Scolavino S, Johnson SR, Klibanski A. A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells. J Clin Endocrinol Metab 2003, 88:5119-5126. 10.1210/jc.2003-030222, 14602737.
29. Kiss T. Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions. Cell 2002, 109:145-148. 10.1016/S0092-8674(02)00718-3, 12007400.
30. Tycowski KT, Aab A, Steitz JA. Guide RNAs with 5′ caps and novel box C/D snoRNA-like domains formodification of snRNAs inmetazoa. Curr Biol 2004, 4:1985-1995.
31. Chien CH, Sun YM, Chang WC, Chiang-Hsieh PY, Lee TY, Horng JT, Tsou AP, Huang HD. Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data. Nucleic Acids Res 2011, 39:9345-9356. 10.1093/nar/gkr604, 3241639, 21821656.
32. Suzuki Y, Ishihara D, Sasaki M, Nakagawa H, Hata H, Tsunoda T, Watanabe M, Komatsu T, Ota T, Isogai T, Suyama A, Sugano S. Statistical analysis of the 5′ untranslated region of human mRNA using “ Oligo-Capped“ cDNA libraries. Genomics 2000, 64:286-297. 10.1006/geno.2000.6076, 10756096.
33. Ferreira HJ, Heyn H, Moutinho C, Esteller M. CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer. RNA Biol 2012, 9:881-890. 10.4161/rna.19353, 3495749, 22617881.
34. Zhang X, Gejman R, Mahta A, Zhong Y, Rice KA, Zhou Y, Cheunsuchon P, Louis DN, Klibanski A. Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progression. Cancer Res 2010, 70:2350-2358. 10.1158/0008-5472.CAN-09-3885, 2987571, 20179190.
35. Zhao J, Dahle D, Zhou Y, Zhang X, Klibanski A. Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. J Clin Endocrinol Metab 2005, 90:2179-2186. 10.1210/jc.2004-1848, 15644399.
36. Benetatos L, Dasoula A, Hatzimichael E, Georgiou I, Syrrou M, Bourantas KL. Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene inmultiple myeloma. Clin Lymphoma Myeloma 2008, 8:171-175. 10.3816/CLM.2008.n.021, 18650181.
37. Ozsolak F, Poling LL, Wang Z, Liu H, Liu XS, Roeder RG, Zhang X, Song JS, Fisher DE. Chromatin structure analyses identify miRNA promoters. Genes Dev 2008, 22:3172-3183. 10.1101/gad.1706508, 2593607, 19056895.
38. Barski A, Jothi R, Cuddapah S, Cui K, Roh TY, Schones DE, Zhao K. Chromatin poises miRNA-and protein-coding genes for expression. Genome Res 2009, 19:1742-1751. 10.1101/gr.090951.109, 2765269, 19713549.
39. Bajic VB, Tan SL, Suzuki Y, Sugano S. Promoter prediction analysis on the whole human genome. Nat Biotechnol 2004, 22:1467-1473. 10.1038/nbt1032, 15529174.
40. Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaillé J. A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res 2004, 14:1741-1748. 10.1101/gr.2743304, 515320, 15310658.
41. Manodoro F, Marzec J, Chaplin T, Miraki-Moud F, Moravcsik E, Jovanovic JV. Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia. Blood 2014, 123:2066-2074. 10.1182/blood-2012-12-469833, 24493669.
42. Ni J, Tien AL, Fournier MJ. Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA. Cell 1997, 89:565-573. 10.1016/S0092-8674(00)80238-X, 9160748.
43. Scott MS, Ono M. From snoRNA to miRNA: dual function regulatory non-coding RNAs. Biochimie 2011, 93:1987-1992. 10.1016/j.biochi.2011.05.026, 3476530, 21664409.
44. Yin QF, Yang L, Zhang Y, Xiang JF, Wu YW, Carmichael GG, Chen LL. Long noncoding RNAs with snoRNA ends. Mol Cell 2012, 48:219-230. 10.1016/j.molcel.2012.07.033, 22959273.
45. Kondoh NI, Wakatsuki T, Hada A, Shuda M, Tanaka K, Arai M, Yamamoto M. Genetic and epigenetic events in human hepatocarcinogenesis. Int J Oncol 2001, 18(6):1271-1278.
46. Massague J. TGF-β in cancer. Cell 2008, 134:215-230. 10.1016/j.cell.2008.07.001, 3512574, 18662538.
47. Huynh H, Nguyen TT, Chow KH, Tan PH, Soo KC, Tran E. Over-expression of the mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK in hepatocellular carcinoma: its role in tumor progression and apoptosis. BMC Gastroenterol 2003, 3:19. 10.1186/1471-230X-3-19, 317301, 12906713.
48. Calvisi DF, Pascale RM, Feo F. Dissection of signal transduction pathways as a tool for the development of targeted therapies of hepatocellular carcinoma. Rev Recent Clin Trials 2007, 2:217-236. 10.2174/157488707781662715, 18474008.