메뉴 건너뛰기




Volumn 66, Issue 9, 2014, Pages 2590-2600

Distinct effects of methotrexate and etanercept on the B cell compartment in patients with juvenile idiopathic arthritis

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; ETANERCEPT; IMMUNOGLOBULIN; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84907381004     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38736     Document Type: Article
Times cited : (53)

References (50)
  • 1
    • 84860717451 scopus 로고    scopus 로고
    • B-cell pathology in juvenile idiopathic arthritis
    • Wiegering V, Girschick HJ, Morbach H. B-cell pathology in juvenile idiopathic arthritis. Arthritis 2010;2010:759868.
    • (2010) Arthritis , vol.2010 , pp. 759868
    • Wiegering, V.1    Girschick, H.J.2    Morbach, H.3
  • 2
    • 20544460562 scopus 로고    scopus 로고
    • Phenotypic and functional characterisation of CCR7+ and CCR7- CD4+ memory T cells homing to the joints in juvenile idiopathic arthritis
    • Gattorno M, Prigione I, Morandi F, Gregorio A, Chiesa S, Ferlito F, et al. Phenotypic and functional characterisation of CCR7+ and CCR7- CD4+ memory T cells homing to the joints in juvenile idiopathic arthritis. Arthritis Res Ther 2005;7:R256-67.
    • (2005) Arthritis Res Ther , vol.7
    • Gattorno, M.1    Prigione, I.2    Morandi, F.3    Gregorio, A.4    Chiesa, S.5    Ferlito, F.6
  • 3
    • 79957643739 scopus 로고    scopus 로고
    • The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis
    • Lin YT, Wang CT, Gershwin ME, Chiang BL. The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis. Autoimmun Rev 2011;10:482-9.
    • (2011) Autoimmun Rev , vol.10 , pp. 482-489
    • Lin, Y.T.1    Wang, C.T.2    Gershwin, M.E.3    Chiang, B.L.4
  • 4
    • 84867112016 scopus 로고    scopus 로고
    • Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis
    • Omoyinmi E, Hamaoui R, Pesenacker A, Nistala K, Moncrieffe H, Ursu S, et al. Th1 and Th17 cell subpopulations are enriched in the peripheral blood of patients with systemic juvenile idiopathic arthritis. Rheumatology (Oxford) 2012;51:1881-6.
    • (2012) Rheumatology (Oxford) , vol.51 , pp. 1881-1886
    • Omoyinmi, E.1    Hamaoui, R.2    Pesenacker, A.3    Nistala, K.4    Moncrieffe, H.5    Ursu, S.6
  • 5
    • 72049121646 scopus 로고    scopus 로고
    • Using biology of disease to understand and guide therapy of JIA
    • Prakken BJ, Albani S. Using biology of disease to understand and guide therapy of JIA. Best Pract Res Clin Rheumatol 2009;23:599-608.
    • (2009) Best Pract Res Clin Rheumatol , vol.23 , pp. 599-608
    • Prakken, B.J.1    Albani, S.2
  • 6
    • 84869870503 scopus 로고    scopus 로고
    • Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity
    • Sweet RA, Lee SK, Vinuesa CG. Developing connections amongst key cytokines and dysregulated germinal centers in autoimmunity. Curr Opin Immunol 2012;24:658-64.
    • (2012) Curr Opin Immunol , vol.24 , pp. 658-664
    • Sweet, R.A.1    Lee, S.K.2    Vinuesa, C.G.3
  • 7
    • 80052616538 scopus 로고    scopus 로고
    • Efficacy and safety of repeat courses of rituximab treatment in patients with severe refractory juvenile idiopathic arthritis
    • Alexeeva EI, Valieva SI, Bzarova TM, Semikina EL, Isaeva KB, Lisitsyn AO, et al. Efficacy and safety of repeat courses of rituximab treatment in patients with severe refractory juvenile idiopathic arthritis. Clin Rheumatol 2011;30:1163-72.
    • (2011) Clin Rheumatol , vol.30 , pp. 1163-1172
    • Alexeeva, E.I.1    Valieva, S.I.2    Bzarova, T.M.3    Semikina, E.L.4    Isaeva, K.B.5    Lisitsyn, A.O.6
  • 8
    • 84878705453 scopus 로고    scopus 로고
    • Rituximab: Rescue therapy in life-threatening complications or refractory autoimmune diseases: A single center experience
    • Braun-Moscovici Y, Butbul-Aviel Y, Guralnik L, Toledano K, Markovits D, Rozin A, et al. Rituximab: rescue therapy in life-threatening complications or refractory autoimmune diseases: a single center experience. Rheumatol Int 2013;33:1495-504.
    • (2013) Rheumatol Int , vol.33 , pp. 1495-1504
    • Braun-Moscovici, Y.1    Butbul-Aviel, Y.2    Guralnik, L.3    Toledano, K.4    Markovits, D.5    Rozin, A.6
  • 9
    • 73349104126 scopus 로고    scopus 로고
    • Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: Depletion of memory B cells correlates with clinical response
    • Nakou M, Katsikas G, Sidiropoulos P, Bertsias G, Papadimitraki E, Raptopoulou A, et al. Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response. Arthritis Res Ther 2009;11:R131.
    • (2009) Arthritis Res Ther , vol.11
    • Nakou, M.1    Katsikas, G.2    Sidiropoulos, P.3    Bertsias, G.4    Papadimitraki, E.5    Raptopoulou, A.6
  • 12
    • 84873944529 scopus 로고    scopus 로고
    • Intra-articular methotrexate associated to lipid nanoemulsions: Anti-inflammatory effect upon antigen-induced arthritis
    • Mello SB, Tavares ER, Bulgarelli A, Bonfa E, Maranhao RC. Intra-articular methotrexate associated to lipid nanoemulsions: anti-inflammatory effect upon antigen-induced arthritis. Int J Nanomedicine 2013;8:443-9.
    • (2013) Int J Nanomedicine , vol.8 , pp. 443-449
    • Mello, S.B.1    Tavares, E.R.2    Bulgarelli, A.3    Bonfa, E.4    Maranhao, R.C.5
  • 15
    • 79951501790 scopus 로고    scopus 로고
    • Cellular mechanisms of TNF function in models of inflammation and autoimmunity
    • Apostolaki M, Armaka M, Victoratos P, Kollias G. Cellular mechanisms of TNF function in models of inflammation and autoimmunity. Curr Dir Autoimmun 2010;11:1-26.
    • (2010) Curr Dir Autoimmun , vol.11 , pp. 1-26
    • Apostolaki, M.1    Armaka, M.2    Victoratos, P.3    Kollias, G.4
  • 16
    • 39649097890 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks
    • Anolik JH, Ravikumar R, Barnard J, Owen T, Almudevar A, Milner EC, et al. Anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks. J Immunol 2008;180:688-92.
    • (2008) J Immunol , vol.180 , pp. 688-692
    • Anolik, J.H.1    Ravikumar, R.2    Barnard, J.3    Owen, T.4    Almudevar, A.5    Milner, E.C.6
  • 17
    • 67649472564 scopus 로고    scopus 로고
    • Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor
    • Souto-Carneiro MM, Mahadevan V, Takada K, Fritsch-Stork R, Nanki T, Brown M, et al. Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor. Arthritis Res Ther 2009;11:R84.
    • (2009) Arthritis Res Ther , vol.11
    • Souto-Carneiro, M.M.1    Mahadevan, V.2    Takada, K.3    Fritsch-Stork, R.4    Nanki, T.5    Brown, M.6
  • 18
    • 84856378337 scopus 로고    scopus 로고
    • Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis
    • Vinay DS, Kwon BS. Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis. Cytokine 2012;57:305-12.
    • (2012) Cytokine , vol.57 , pp. 305-312
    • Vinay, D.S.1    Kwon, B.S.2
  • 20
    • 78049494232 scopus 로고    scopus 로고
    • BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling
    • Rowland SL, Leahy KF, Halverson R, Torres RM, Pelanda R. BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling. J Immunol 2010;185:4570-81.
    • (2010) J Immunol , vol.185 , pp. 4570-4581
    • Rowland, S.L.1    Leahy, K.F.2    Halverson, R.3    Torres, R.M.4    Pelanda, R.5
  • 21
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
    • DOI 10.1126/science.1061964
    • Schiemann B, Gommerman JL, Vora K, Cachero TG, Shulga-Morskaya S, Dobles M, et al. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 2001;293:2111-4. (Pubitemid 32848063)
    • (2001) Science , vol.293 , Issue.5537 , pp. 2111-2114
    • Schiemann, B.1    Gommerman, J.L.2    Vora, K.3    Cachero, T.G.4    Shutga-Morskaya, S.5    Dobles, M.6    Frew, E.7    Scott, M.L.8
  • 22
    • 34247574625 scopus 로고    scopus 로고
    • B cells and the BAFF/APRIL axis: Fast-forward on autoimmunity and signaling
    • DOI 10.1016/j.coi.2007.04.008, PII S095279150700060X, Lymphocyte activation/Lymphocyte effector functions
    • Mackay F, Silveira PA, Brink R. B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 2007;19:327-36. (Pubitemid 46687013)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.3 , pp. 327-336
    • Mackay, F.1    Silveira, P.A.2    Brink, R.3
  • 23
    • 84861694711 scopus 로고    scopus 로고
    • Follicular helper T cells in immunity and systemic autoimmunity
    • Craft JE. Follicular helper T cells in immunity and systemic autoimmunity. Nat Rev Rheumatol 2012;8:337-47.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 337-347
    • Craft, J.E.1
  • 24
    • 84862298255 scopus 로고    scopus 로고
    • Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis
    • Ma J, Zhu C, Ma B, Tian J, Baidoo SE, Mao C, et al. Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis. Clin Dev Immunol 2012;2012:827480.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 827480
    • Ma, J.1    Zhu, C.2    Ma, B.3    Tian, J.4    Baidoo, S.E.5    Mao, C.6
  • 25
    • 7544222361 scopus 로고    scopus 로고
    • Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis
    • the Childhood Arthritis and Rheumatology Research Alliance, the Pediatric Rheumatology International Trials Organization, and the Pediatric Rheumatology Collaborative Study Group
    • Wallace CA, Ruperto N, Giannini E, the Childhood Arthritis and Rheumatology Research Alliance, the Pediatric Rheumatology International Trials Organization, and the Pediatric Rheumatology Collaborative Study Group. Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis. J Rheumatol 2004;31:2290-4.
    • (2004) J Rheumatol , vol.31 , pp. 2290-2294
    • Wallace, C.A.1    Ruperto, N.2    Giannini, E.3
  • 27
    • 38749090153 scopus 로고    scopus 로고
    • Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation
    • DOI 10.1084/jem.20071088
    • Meyer-Bahlburg A, Andrews SF, Yu KO, Porcelli SA, Rawlings DJ. Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation. J Exp Med 2008;205:155-68. (Pubitemid 351185723)
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.1 , pp. 155-168
    • Meyer-Bahlburg, A.1    Andrews, S.F.2    Yu, K.O.A.3    Porcelli, S.A.4    Rawlings, D.J.5
  • 28
    • 0141783731 scopus 로고    scopus 로고
    • Decrease of B-cells and autoantibodies after low-dose methotrexate
    • DOI 10.1016/S0753-3322(03)00086-6
    • Bohm I. Decrease of B-cells and autoantibodies after low-dose methotrexate. Biomed Pharmacother 2003;57:278-81. (Pubitemid 37123098)
    • (2003) Biomedicine and Pharmacotherapy , vol.57 , Issue.7 , pp. 278-281
    • Bohm, I.1
  • 31
    • 0036311848 scopus 로고    scopus 로고
    • Immunoglobulin levels in methotrexate treated paediatric rheumatology patients
    • DOI 10.1136/adc.87.2.147
    • Rackham OJ, Sills JA, Davidson JE. Immunoglobulin levels in methotrexate treated paediatric rheumatology patients. Arch Dis Child 2002;87:147-8. (Pubitemid 34828023)
    • (2002) Archives of Disease in Childhood , vol.87 , Issue.2 , pp. 147-148
    • Rackham, O.J.1    Sills, J.A.2    Davidson, J.E.3
  • 32
    • 70349246999 scopus 로고    scopus 로고
    • Tolerance checkpoints in B-cell development: Johnny B good
    • Tussiwand R, Bosco N, Ceredig R, Rolink AG. Tolerance checkpoints in B-cell development: Johnny B good. Eur J Immunol 2009;39:2317-24.
    • (2009) Eur J Immunol , vol.39 , pp. 2317-2324
    • Tussiwand, R.1    Bosco, N.2    Ceredig, R.3    Rolink, A.G.4
  • 33
    • 77955450480 scopus 로고    scopus 로고
    • Predictors of poor response to methotrexate in polyarticular-course juvenile idiopathic arthritis: Analysis of the PRINTO methotrexate trial
    • Vilca I, Munitis PG, Pistorio A, Ravelli A, Buoncompagni A, Bica B, et al. Predictors of poor response to methotrexate in polyarticular-course juvenile idiopathic arthritis: analysis of the PRINTO methotrexate trial. Ann Rheum Dis 2010;69:1479-83.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1479-1483
    • Vilca, I.1    Munitis, P.G.2    Pistorio, A.3    Ravelli, A.4    Buoncompagni, A.5    Bica, B.6
  • 34
    • 84867399904 scopus 로고    scopus 로고
    • Methotrexate reduces immunogenicity in adalimumab treated rheumatoid arthritis patients in a dose dependent manner
    • Krieckaert CL, Nurmohamed MT, Wolbink GJ. Methotrexate reduces immunogenicity in adalimumab treated rheumatoid arthritis patients in a dose dependent manner. Ann Rheum Dis 2012;71:1914-5.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1914-1915
    • Krieckaert, C.L.1    Nurmohamed, M.T.2    Wolbink, G.J.3
  • 35
    • 84885292454 scopus 로고    scopus 로고
    • Drug levels, anti-drug antibodies, and clinical efficacy of the anti-TNFα biologics in rheumatic diseases
    • Mok CC, van der Kleij D, Wolbink GJ. Drug levels, anti-drug antibodies, and clinical efficacy of the anti-TNFα biologics in rheumatic diseases. Clin Rheumatol 2013;32:1429-35.
    • (2013) Clin Rheumatol , vol.32 , pp. 1429-1435
    • Mok, C.C.1    Van Der Kleij, D.2    Wolbink, G.J.3
  • 36
    • 0034972257 scopus 로고    scopus 로고
    • Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
    • DOI 10.1002/1529-0131(200106)44:6<1313::AID-ART223
    • Cheema GS, Roschke V, Hilbert DM, Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 2001;44:1313-9. (Pubitemid 32537529)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.6 , pp. 1313-1319
    • Cheema, G.S.1    Roschke, V.2    Hilbert, D.M.3    Stohl, W.4
  • 39
    • 84860596182 scopus 로고    scopus 로고
    • Elevated BAFF (BLyS) and APRIL in Juvenile idiopathic arthritis patients: Relation to clinical manifestations and disease activity
    • Gheita TA, Bassyouni IH, Emad Y, el-Din AM, Abdel-Rasheed E, Hussein H. Elevated BAFF (BLyS) and APRIL in Juvenile idiopathic arthritis patients: relation to clinical manifestations and disease activity. Joint Bone Spine 2012;79:285-90.
    • (2012) Joint Bone Spine , vol.79 , pp. 285-290
    • Gheita, T.A.1    Bassyouni, I.H.2    Emad, Y.3    El-Din, A.M.4    Abdel-Rasheed, E.5    Hussein, H.6
  • 40
    • 70350527321 scopus 로고    scopus 로고
    • B lymphocyte stimulator expression in pediatric systemic lupus erythematosus and juvenile idiopathic arthritis patients
    • Hong SD, Reiff A, Yang HT, Migone TS, Ward CD, Marzan K, et al. B lymphocyte stimulator expression in pediatric systemic lupus erythematosus and juvenile idiopathic arthritis patients. Arthritis Rheum 2009;60:3400-9.
    • (2009) Arthritis Rheum , vol.60 , pp. 3400-3409
    • Hong, S.D.1    Reiff, A.2    Yang, H.T.3    Migone, T.S.4    Ward, C.D.5    Marzan, K.6
  • 41
    • 35348847343 scopus 로고    scopus 로고
    • BAFF synthesis by rheumatoid synoviocytes is positively controlled by α5β1 integrin stimulation and is negatively regulated by tumor necrosis factor α and toll-like receptor ligands
    • DOI 10.1002/art.22915
    • Alsaleh G, Messer L, Semaan N, Boulanger N, Gottenberg JE, Sibilia J, et al. BAFF synthesis by rheumatoid synoviocytes is positively controlled by α5β1 integrin stimulation and is negatively regulated by tumor necrosis factor α and Toll-like receptor ligands. Arthritis Rheum 2007;56:3202-14. (Pubitemid 47585415)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.10 , pp. 3202-3214
    • Alsaleh, G.1    Messer, L.2    Semaan, N.3    Boulanger, N.4    Gottenberg, J.-E.5    Sibilia, J.6    Wachsmann, D.7
  • 42
    • 84879494471 scopus 로고    scopus 로고
    • B cell activating factor-dependent expression of vascular endothelial growth factor in MH7A human synoviocytes stimulated with tumor necrosis factor-α
    • Lee GH, Lee J, Lee JW, Choi WS, Moon EY. B cell activating factor-dependent expression of vascular endothelial growth factor in MH7A human synoviocytes stimulated with tumor necrosis factor-α. Int Immunopharmacol 2013;17:142-7.
    • (2013) Int Immunopharmacol , vol.17 , pp. 142-147
    • Lee, G.H.1    Lee, J.2    Lee, J.W.3    Choi, W.S.4    Moon, E.Y.5
  • 43
    • 11844301640 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines
    • Ohata J, Zvaifler NJ, Nishio M, Boyle DL, Kalled SL, Carson DA, et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in response to proinflammatory cytokines. J Immunol 2005;174:864-70. (Pubitemid 40094281)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 864-870
    • Ohata, J.1    Zvaifler, N.J.2    Nishio, M.3    Boyle, D.L.4    Kalled, S.L.5    Carson, D.A.6    Kipps, T.J.7
  • 44
    • 34447515625 scopus 로고    scopus 로고
    • Tumor necrosis factor α activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint
    • DOI 10.1002/art.22697
    • Assi LK, Wong SH, Ludwig A, Raza K, Gordon C, Salmon M, et al. Tumor necrosis factor α activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint. Arthritis Rheum 2007;56:1776-86. (Pubitemid 47110377)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.6 , pp. 1776-1786
    • Assi, L.K.1    See, H.W.2    Ludwig, A.3    Raza, K.4    Gordon, C.5    Salmon, M.6    Lord, J.M.7    Scheel-Toellner, D.8
  • 45
    • 47949086146 scopus 로고    scopus 로고
    • B lymphocyte stimulator expression in patients with rheumatoid arthritis treated with tumour necrosis factor a antagonists: Differential effects between good and poor clinical responders
    • La DT, Collins CE, Yang HT, Migone TS, Stohl W. B lymphocyte stimulator expression in patients with rheumatoid arthritis treated with tumour necrosis factor a antagonists: differential effects between good and poor clinical responders. Ann Rheum Dis 2008;67:1132-8.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1132-1138
    • La, D.T.1    Collins, C.E.2    Yang, H.T.3    Migone, T.S.4    Stohl, W.5
  • 46
    • 84876889502 scopus 로고    scopus 로고
    • Efficacy and safety of belimumab in patients with rheumatoid arthritis: A phase II, randomized, double-blind, placebo-controlled, dose-ranging study
    • Stohl W, Merrill JT, McKay JD, Lisse JR, Zhong ZJ, Freimuth WW, et al. Efficacy and safety of belimumab in patients with rheumatoid arthritis: a phase II, randomized, double-blind, placebo-controlled, dose-ranging study. J Rheumatol 2013;40:579-89.
    • (2013) J Rheumatol , vol.40 , pp. 579-589
    • Stohl, W.1    Merrill, J.T.2    McKay, J.D.3    Lisse, J.R.4    Zhong, Z.J.5    Freimuth, W.W.6
  • 48
    • 84878257992 scopus 로고    scopus 로고
    • The good, the bad and the ugly-TFH cells in human health and disease
    • Tangye SG, Ma CS, Brink R, Deenick EK. The good, the bad and the ugly-TFH cells in human health and disease. Nat Rev Immunol 2013;13:412-26.
    • (2013) Nat Rev Immunol , vol.13 , pp. 412-426
    • Tangye, S.G.1    Ma, C.S.2    Brink, R.3    Deenick, E.K.4
  • 49
    • 74849138095 scopus 로고    scopus 로고
    • Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
    • Simpson N, Gatenby PA, Wilson A, Malik S, Fulcher DA, Tangye SG, et al. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum 2010;62:234-44.
    • (2010) Arthritis Rheum , vol.62 , pp. 234-244
    • Simpson, N.1    Gatenby, P.A.2    Wilson, A.3    Malik, S.4    Fulcher, D.A.5    Tangye, S.G.6
  • 50
    • 65249098979 scopus 로고    scopus 로고
    • Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): Preliminary data from the German JIA Registry
    • Horneff G, De Bock F, Foeldvari I, Girschick HJ, Michels H, Moebius D, et al. Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): preliminary data from the German JIA Registry. Ann Rheum Dis 2009;68:519-25.
    • (2009) Ann Rheum Dis , vol.68 , pp. 519-525
    • Horneff, G.1    De Bock, F.2    Foeldvari, I.3    Girschick, H.J.4    Michels, H.5    Moebius, D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.