Intra-articular methotrexate associated to lipid nanoemulsions: Anti-inflammatory effect upon antigen-induced arthritis

International Journal of Nanomedicine

Volumn 8, Issue , 2013, Pages 443-449

  Mello, Suzana B V ^a   Tavares, Elaine R ^a   Bulgarelli, Adriana ^a   Bonfá, Eloisa ^a   Maranhão, Raul C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antigen induced arthritis; Arthritis; Cholesterol; Methotrexate; Nanoparticles

Indexed keywords

ANTIGEN; BOVINE SERUM ALBUMIN; CHOLESTEROL; CHOLESTEROL OLEATE; HYDROCHLORIC ACID; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; METHOTREXATE; PHOSPHATIDYLCHOLINE; POLYSORBATE 80; SODIUM CHLORIDE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL COMPOSITION; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG DOSE INCREASE; DRUG FORMULATION; HISTOPATHOLOGY; LEUKOCYTE COUNT; LIGHT SCATTERING; NANOEMULSION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PARTICLE SIZE; PROTEIN ANALYSIS; PROTEIN METHYLATION; PROTEIN TRANSPORT; RABBIT; RHEUMATOID ARTHRITIS; SINGLE DRUG DOSE; SYNOVIAL FLUID; SYNOVIUM; ZETA POTENTIAL;

ANTIGEN-INDUCED ARTHRITIS; ARTHRITIS; CHOLESTEROL; METHOTREXATE; NANOPARTICLES;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CYTOKINES; EMULSIONS; INJECTIONS, INTRA-ARTICULAR; LIPIDS; METHOTREXATE; NEUTROPHIL INFILTRATION; RABBITS; SYNOVIAL FLUID; SYNOVIAL MEMBRANE;

EID: 84873944529     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S29392     Document Type: Article

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