Overexpression of oxidored-nitro domain containing protein 1 induces growth inhibition and apoptosis in human prostate cancer PC3 cells

Oncology Reports

Volumn 32, Issue 5, 2014, Pages 1939-1946

  Shan, Zhongjie ^a   Hou, Qinglan ^a   Zhang, Nan ^a   Guo, Liang ^a   Zhang, Xinheng ^b   Ma, Yaohui ^a   Zhou, Yudong ^a  

^a HENAN PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b Sanmenxia Central Hospital   (China)

Author keywords

Apoptosis; MAPK pathway; Oxidored nitro domain containing protein 1; Proliferation; Prostate cancer

Indexed keywords

CASPASE 3; MITOGEN ACTIVATED PROTEIN KINASE; OXIDORED NITRO DOMAIN CONTAINING PROTEIN 1; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; OSCP1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DU145 CELL LINE; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PC3 CELL LINE; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CANCER TRANSPLANTATION; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; PROSTATE TUMOR; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROSTATIC NEOPLASMS;

EID: 84907299163     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3407     Document Type: Article

References (32)

1. Siegel R, Naishadham D and Jemal A: Cancer statistics, 2012. CA Cancer J Clin 62: 10-29, 2012.
2. Rasheed SAK, Teo CR, Beillard EJ, Voorhoeve PM and Casey PJ: MicroRNA-182 and microRNA-200a control G-protein subunit α-13 (GNA13) expression and cell invasion synergistically in prostate cancer cells. J Biol Chem 288: 7986-7995, 2013.
3. Xiang B, Wang W, Li W, Li X, Li X and Li G: Differential expression of oxidored nitro domain containing protein 1 (NOR1), in mouse tissues and in normal and cancerous human tissues. Gene 493: 18-26, 2012.
4. Li W, Li X, Wang W, et al: NOR1 is an HSF1-And NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma. Carcinogenesis 32: 1305-1314, 2011.
5. Ouyang J, Wu M, Huang C, Cao L and Li G: Overexpression of oxidored-nitro domain containing protein 1 inhibits human nasopharyngeal carcinoma and cervical cancer cell proliferation and induces apoptosis: Involvement of mitochondrial apoptotic pathways. Oncol Rep 29: 79-86, 2013.
6. Nie X, Zhang B, Li X, et al: Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE1 nasopharyngeal carcinoma cell line. J Cancer Res Clin Oncol 129: 410-414, 2003.
7. Kroeger H, Jelinek J, Estécio MR, et al: Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse. Blood 112: 1366-1373, 2008.
8. Gui R, Liu J, Li D, Tang H, Feng Z and Nie X: NOR1 enhanced CB1954 induced cell cytotoxicity in HepG2 is dependent on Grb2 mediated MAPK pathway. Bioinformatics and Biomedical Engineering (iCBBE), 2010 4th International Conference on IEEE, pp1-7, 2010.
9. Shen L, Kantarjian H, Guo Y, et al: DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes. J Clin Oncol 28: 605-613, 2010.
10. Jelinek J, Gharibyan V, Estecio MR, et al: Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia. PloS One 6: e22110, 2011.
11. Brentnall M, Rodriguez-Menacol L, De Guevara RL, Cepero E and Boise LH: Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis. BMC Cell Biol 14: 32, 2013.
12. Kuribayashi K, Finnberg NK, Jeffers JR, Zambetti GP and El-Deiry WS: The relative contribution of pro-Apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo. Cell Cycle 10: 2380-2389, 2011.
13. D'Sa-Eipper C, Leonard JR, Putcha G, et al: DNA damageinduced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3. Development 128: 137-146, 2001.
14. Porter AG and Jänicke RU: Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6: 99-104, 1999.
15. Boucher MJ, Morisset J, Vachon PH, Reed JC, Lainé J and Rivard N: MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-XL, and Mcl-1 and promotes survival of human pancreatic cancer cells. J Cell Biochem 79: 355-369, 2000.
16. Wei MC, Zong WX, Cheng EHY, et al: Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292: 727-730, 2001.
17. Kobayashi Y, Shibusawa A, Saito H, et al: Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1. J Biol Chem 280: 32332-32339, 2005.
18. Lin JG, Chen GW, Li TM, Chouh ST, Tan TW and Chung JG: Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway. J Urol 175: 343-347, 2006.
19. Trotta AP, Need EF, Selth LA, et al: Knockdown of the cochaperone SGTA results in the suppression of androgen and PI3K/Akt signaling and inhibition of prostate cancer cell proliferation. Int J Cancer 133: 2812-2823, 2013.
20. Zhao D, Lin F, Wu X, et al: Pseudolaric acid B induces apoptosis via proteasome-mediated Bcl-2 degradation in hormone-refractory prostate cancer DU145 cells. Toxicol In Vitro 26: 595-602, 2012.
21. Liu Y, Zhang SP and Cai YQ: Cytoprotective effects of selenium on cadmium-induced LL C-PK1 cells apoptosis by activating JNK pathway. Toxicol In Vitro 21: 677-684, 2007.
22. Tucci P, Agostini M, Grespi F, et al: Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci USA 109: 15312-15317, 2012.
23. Livak K and Schmittgen T: Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T) method. Methods 25: 402-408, 2001.
24. Kato T, Fujita Y, Nakane K, et al: ETS1 promotes chemoresistance and invasion of paclitaxel-resistant, hormone-refractory PC3 prostate cancer cells by up-regulating MDR1 and MMP9 expression. Biochem Biophys Res Commun 417: 966-971, 2012.
25. Tanaka H, Kono E, Tran CP, et al: Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance. Nat Med 16: 1414-1420, 2010.
26. Aghaei M, Karami-Tehrani F, Panjehpour M, Salami S and Fallahian F: Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and-independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3. Prostate 72: 361-375, 2012.
27. Xu X, Gao X, Jin L, et al: Antiproliferation and cell apoptosis inducing bioactivities of constituents from Dysosma versipellis in PC3 and Bcap-37 cell lines. Cell Div 6: 14, 2011.
28. De Zutter GS and Davis RJ: Pro-Apoptotic gene expression mediated by the p38 mitogen-Activated protein kinase signal transduction pathway. Proc Natl Acad Sci USA 98: 6168-6173, 2001.
29. Murillo H, Schmidt LJ and Tindall DJ: Tyrphostin AG825 triggers p38 mitogen-Activated protein kinase-dependent apoptosis in androgen-independent prostate cancer cells C4 and C4-2. Cancer Res 61: 7408-7412, 2001.
30. Tanaka Y, Gavrielides MV, Mitsuuchi Y, Fujii T and Kazanietz MG: Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway. J Biol Chem 278: 33753-33762, 2003.
31. Marsden VS, O'Connor L, O'Reilly LA, et al: Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 419: 634-637, 2002.
32. Cory S and Adams JM: The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2: 647-656, 2002.