메뉴 건너뛰기




Volumn 29, Issue 2, 2014, Pages 241-249

Role of IL28B for chronic hepatitis C treatment toward personalized medicine

Author keywords

Direct acting antiviral (DAA); Genome wide association study (GWAS); Hepatitis C virus (HCV); Interleukin 28B (IL28B)

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 28B; PEGINTERFERON; RIBAVIRIN; ALPHA INTERFERON; ANTIVIRUS AGENT; IFNL4 PROTEIN, HUMAN; IL28B PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; MACROGOL DERIVATIVE; PEGINTERFERON ALPHA2A; PEGINTERFERON ALPHA2B; RECOMBINANT PROTEIN;

EID: 84907284086     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12475     Document Type: Review
Times cited : (50)

References (92)
  • 1
    • 59149085501 scopus 로고    scopus 로고
    • The global burden of hepatitis C
    • Lavanchy D. The global burden of hepatitis C. Liver Int. 2009; 29 (Suppl. 1): 74-81.
    • (2009) Liver Int. , vol.29 , pp. 74-81
    • Lavanchy, D.1
  • 2
    • 10744229781 scopus 로고    scopus 로고
    • Benefit of interferon therapy in hepatocellular carcinoma prevention for individual patients with chronic hepatitis C
    • Yoshida H, Tateishi R, Arakawa Y etal. Benefit of interferon therapy in hepatocellular carcinoma prevention for individual patients with chronic hepatitis C. Gut 2004; 53: 425-430.
    • (2004) Gut , vol.53 , pp. 425-430
    • Yoshida, H.1    Tateishi, R.2    Arakawa, Y.3
  • 3
    • 62749203302 scopus 로고    scopus 로고
    • Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients
    • George SL, Bacon BR, Brunt EM, Mihindukulasuriya KL, Hoffmann J, Di Bisceglie AM. Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients. Hepatology 2009; 49: 729-738.
    • (2009) Hepatology , vol.49 , pp. 729-738
    • George, S.L.1    Bacon, B.R.2    Brunt, E.M.3    Mihindukulasuriya, K.L.4    Hoffmann, J.5    Di Bisceglie, A.M.6
  • 4
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Fried MW, Shiffman ML, Reddy KR etal. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N. Engl. J. Med. 2002; 347: 975-982.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 5
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette H Jr, Morgan TR etal. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann. Intern. Med. 2004; 140: 346-355.
    • (2004) Ann. Intern. Med. , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette Jr, H.2    Morgan, T.R.3
  • 6
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M etal. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat. Genet. 2009; 41: 1105-1109.
    • (2009) Nat. Genet. , vol.41 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3
  • 7
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ etal. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009; 461: 399-401.
    • (2009) Nature , vol.461 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 8
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
    • Suppiah V, Moldovan M, Ahlenstiel G etal. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat. Genet. 2009; 41: 1100-1104.
    • (2009) Nat. Genet. , vol.41 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3
  • 9
    • 70349966196 scopus 로고    scopus 로고
    • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
    • Thomas DL, Thio CL, Martin MP etal. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature 2009; 461: 798-801.
    • (2009) Nature , vol.461 , pp. 798-801
    • Thomas, D.L.1    Thio, C.L.2    Martin, M.P.3
  • 10
    • 77954368611 scopus 로고    scopus 로고
    • lambda-Interferons and the single nucleotide polymorphisms: a milestone to tailor-made therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M, Tokunaga K, Mizokami M. lambda-Interferons and the single nucleotide polymorphisms: a milestone to tailor-made therapy for chronic hepatitis C. Hepatol. Res. 2010; 40: 449-460.
    • (2010) Hepatol. Res. , vol.40 , pp. 449-460
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3    Tokunaga, K.4    Mizokami, M.5
  • 11
    • 78751508078 scopus 로고    scopus 로고
    • Hepatitis C pharmacogenetics: state of the art in
    • Afdhal NH, McHutchison JG, Zeuzem S etal. Hepatitis C pharmacogenetics: state of the art in. Hepatology 2010; 53: 336-345.
    • (2010) Hepatology , vol.53 , pp. 336-345
    • Afdhal, N.H.1    McHutchison, J.G.2    Zeuzem, S.3
  • 12
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S etal. Telaprevir for retreatment of HCV infection. N. Engl. J. Med. 2011; 364: 2417-2428.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 13
    • 84865494240 scopus 로고    scopus 로고
    • Factors that predict response of patients with hepatitis C virus infection to boceprevir
    • e1-5
    • Poordad F, Bronowicki JP, Gordon SC etal. Factors that predict response of patients with hepatitis C virus infection to boceprevir. Gastroenterology 2012; 143: 608-18 e1-5.
    • (2012) Gastroenterology , vol.143 , pp. 608-18
    • Poordad, F.1    Bronowicki, J.P.2    Gordon, S.C.3
  • 14
    • 79959438789 scopus 로고    scopus 로고
    • Telaprevir for previously untreated chronic hepatitis C virus infection
    • Jacobson IM, McHutchison JG, Dusheiko G etal. Telaprevir for previously untreated chronic hepatitis C virus infection. N. Engl. J. Med. 2011; 364: 2405-2416.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2405-2416
    • Jacobson, I.M.1    McHutchison, J.G.2    Dusheiko, G.3
  • 15
    • 22344457187 scopus 로고    scopus 로고
    • Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy
    • Akuta N, Suzuki F, Sezaki H etal. Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy. Intervirology 2005; 48: 372-380.
    • (2005) Intervirology , vol.48 , pp. 372-380
    • Akuta, N.1    Suzuki, F.2    Sezaki, H.3
  • 16
    • 9144257569 scopus 로고    scopus 로고
    • Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
    • Enomoto N, Sakuma I, Asahina Y etal. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N. Engl. J. Med. 1996; 334: 77-81.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 77-81
    • Enomoto, N.1    Sakuma, I.2    Asahina, Y.3
  • 17
    • 68249154875 scopus 로고    scopus 로고
    • Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection
    • McHutchison JG, Lawitz EJ, Shiffman ML etal. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N. Engl. J. Med. 2009; 361: 580-593.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 580-593
    • McHutchison, J.G.1    Lawitz, E.J.2    Shiffman, M.L.3
  • 18
    • 0036788338 scopus 로고    scopus 로고
    • Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C
    • McHutchison JG, Manns M, Patel K etal. Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C. Gastroenterology 2002; 123: 1061-1069.
    • (2002) Gastroenterology , vol.123 , pp. 1061-1069
    • McHutchison, J.G.1    Manns, M.2    Patel, K.3
  • 19
    • 33746535101 scopus 로고    scopus 로고
    • Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1
    • Conjeevaram HS, Fried MW, Jeffers LJ etal. Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1. Gastroenterology 2006; 131: 470-477.
    • (2006) Gastroenterology , vol.131 , pp. 470-477
    • Conjeevaram, H.S.1    Fried, M.W.2    Jeffers, L.J.3
  • 20
    • 2542590982 scopus 로고    scopus 로고
    • Peginterferon alfa-2a (40 kd) and ribavirin for black American patients with chronic HCV genotype 1
    • Jeffers LJ, Cassidy W, Howell CD, Hu S, Reddy KR. Peginterferon alfa-2a (40 kd) and ribavirin for black American patients with chronic HCV genotype 1. Hepatology 2004; 39: 1702-1708.
    • (2004) Hepatology , vol.39 , pp. 1702-1708
    • Jeffers, L.J.1    Cassidy, W.2    Howell, C.D.3    Hu, S.4    Reddy, K.R.5
  • 21
    • 2442665224 scopus 로고    scopus 로고
    • Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites
    • Muir AJ, Bornstein JD, Killenberg PG. Peginterferon alfa-2b and ribavirin for the treatment of chronic hepatitis C in blacks and non-Hispanic whites. N. Engl. J. Med. 2004; 350: 2265-2271.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2265-2271
    • Muir, A.J.1    Bornstein, J.D.2    Killenberg, P.G.3
  • 22
    • 0038071786 scopus 로고    scopus 로고
    • The dinucleotide microsatellite polymorphism of the IFNAR1 gene promoter correlates with responsiveness of hepatitis C patients to interferon
    • Matsuyama N, Mishiro S, Sugimoto M etal. The dinucleotide microsatellite polymorphism of the IFNAR1 gene promoter correlates with responsiveness of hepatitis C patients to interferon. Hepatol. Res. 2003; 25: 221-225.
    • (2003) Hepatol. Res. , vol.25 , pp. 221-225
    • Matsuyama, N.1    Mishiro, S.2    Sugimoto, M.3
  • 23
    • 65349098718 scopus 로고    scopus 로고
    • A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C
    • Tsukada H, Ochi H, Maekawa T etal. A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C. Gastroenterology 2009; 136: 1796-1805.
    • (2009) Gastroenterology , vol.136 , pp. 1796-1805
    • Tsukada, H.1    Ochi, H.2    Maekawa, T.3
  • 24
    • 3843075120 scopus 로고    scopus 로고
    • HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection
    • Khakoo SI, Thio CL, Martin MP etal. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 2004; 305: 872-874.
    • (2004) Science , vol.305 , pp. 872-874
    • Khakoo, S.I.1    Thio, C.L.2    Martin, M.P.3
  • 25
    • 65549148158 scopus 로고    scopus 로고
    • Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection
    • Wang JH, Zheng X, Ke X etal. Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection. Virol. J. 2009; 6: 46.
    • (2009) Virol. J. , vol.6 , pp. 46
    • Wang, J.H.1    Zheng, X.2    Ke, X.3
  • 27
    • 77949831342 scopus 로고    scopus 로고
    • Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study
    • 45 e1-7.
    • Rauch A, Kutalik Z, Descombes P etal. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology 2010; 138: 1338-1345, 45 e1-7.
    • (2010) Gastroenterology , vol.138 , pp. 1338-1345
    • Rauch, A.1    Kutalik, Z.2    Descombes, P.3
  • 29
    • 0034718227 scopus 로고    scopus 로고
    • The natural history of hepatitis C virus infection: host, viral, and environmental factors
    • Thomas DL, Astemborski J, Rai RM etal. The natural history of hepatitis C virus infection: host, viral, and environmental factors. JAMA 2000; 284: 450-456.
    • (2000) JAMA , vol.284 , pp. 450-456
    • Thomas, D.L.1    Astemborski, J.2    Rai, R.M.3
  • 30
    • 33644676862 scopus 로고    scopus 로고
    • Correlates of hepatitis C virus (HCV) RNA negativity among HCV-seropositive blood donors
    • Busch MP, Glynn SA, Stramer SL etal. Correlates of hepatitis C virus (HCV) RNA negativity among HCV-seropositive blood donors. Transfusion 2006; 46: 469-475.
    • (2006) Transfusion , vol.46 , pp. 469-475
    • Busch, M.P.1    Glynn, S.A.2    Stramer, S.L.3
  • 31
    • 33947644908 scopus 로고    scopus 로고
    • Treatment of chronic hepatitis C virus in African Americans with genotypes 2 and 3
    • Shiffman ML, Mihas AA, Millwala F etal. Treatment of chronic hepatitis C virus in African Americans with genotypes 2 and 3. Am. J. Gastroenterol. 2007; 102: 761-766.
    • (2007) Am. J. Gastroenterol. , vol.102 , pp. 761-766
    • Shiffman, M.L.1    Mihas, A.A.2    Millwala, F.3
  • 32
    • 77953881002 scopus 로고    scopus 로고
    • Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus
    • Thompson AJ, Muir AJ, Sulkowski MS etal. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology 2010; 139: 120-129.
    • (2010) Gastroenterology , vol.139 , pp. 120-129
    • Thompson, A.J.1    Muir, A.J.2    Sulkowski, M.S.3
  • 33
    • 77951880384 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients
    • Rallon NI, Naggie S, Benito JM etal. Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. AIDS 2010; 24: F23-29.
    • (2010) AIDS , vol.24 , pp. F23-F29
    • Rallon, N.I.1    Naggie, S.2    Benito, J.M.3
  • 34
    • 78049470128 scopus 로고    scopus 로고
    • Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C
    • 85 e1-3.
    • Fukuhara T, Taketomi A, Motomura T etal. Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C. Gastroenterology 2010; 139: 1577-1585, 85 e1-3.
    • (2010) Gastroenterology , vol.139 , pp. 1577-1585
    • Fukuhara, T.1    Taketomi, A.2    Motomura, T.3
  • 35
    • 78751505015 scopus 로고    scopus 로고
    • Interleukin-28B polymorphisms are associated with histological recurrence and treatment response following liver transplantation in patients with hepatitis C virus infection
    • Charlton MR, Thompson A, Veldt BJ etal. Interleukin-28B polymorphisms are associated with histological recurrence and treatment response following liver transplantation in patients with hepatitis C virus infection. Hepatology 2011; 53: 317-324.
    • (2011) Hepatology , vol.53 , pp. 317-324
    • Charlton, M.R.1    Thompson, A.2    Veldt, B.J.3
  • 36
    • 84925580987 scopus 로고    scopus 로고
    • An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response
    • 7 e1.
    • Mangia A, Thompson AJ, Santoro R etal. An IL28B polymorphism determines treatment response of hepatitis C virus genotype 2 or 3 patients who do not achieve a rapid virologic response. Gastroenterology 2010; 139: 821-827, 7 e1.
    • (2010) Gastroenterology , vol.139 , pp. 821-827
    • Mangia, A.1    Thompson, A.J.2    Santoro, R.3
  • 37
    • 79952712673 scopus 로고    scopus 로고
    • Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b
    • Sakamoto N, Nakagawa M, Tanaka Y etal. Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b. J. Med. Virol. 2011; 83: 871-878.
    • (2011) J. Med. Virol. , vol.83 , pp. 871-878
    • Sakamoto, N.1    Nakagawa, M.2    Tanaka, Y.3
  • 38
    • 78649320722 scopus 로고    scopus 로고
    • Role of interleukin-28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients
    • Yu ML, Huang CF, Huang JF etal. Role of interleukin-28B polymorphisms in the treatment of hepatitis C virus genotype 2 infection in Asian patients. Hepatology 2011; 53: 7-13.
    • (2011) Hepatology , vol.53 , pp. 7-13
    • Yu, M.L.1    Huang, C.F.2    Huang, J.F.3
  • 39
    • 79952214262 scopus 로고    scopus 로고
    • IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
    • Moghaddam A, Melum E, Reinton N etal. IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection. Hepatology 2011; 53: 746-754.
    • (2011) Hepatology , vol.53 , pp. 746-754
    • Moghaddam, A.1    Melum, E.2    Reinton, N.3
  • 40
    • 84857359539 scopus 로고    scopus 로고
    • IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C
    • Asselah T, De Muynck S, Broet P etal. IL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C. J. Hepatol. 2012; 56: 527-532.
    • (2012) J. Hepatol. , vol.56 , pp. 527-532
    • Asselah, T.1    De Muynck, S.2    Broet, P.3
  • 41
    • 84870999143 scopus 로고    scopus 로고
    • IL28B polymorphisms predict response to therapy among chronic hepatitis C patients with HCV genotype 4
    • Antaki N, Bibert S, Kebbewar K etal. IL28B polymorphisms predict response to therapy among chronic hepatitis C patients with HCV genotype 4. J. Viral Hepat. 2012; 20: 59-64.
    • (2012) J. Viral Hepat. , vol.20 , pp. 59-64
    • Antaki, N.1    Bibert, S.2    Kebbewar, K.3
  • 42
    • 84879838477 scopus 로고    scopus 로고
    • IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection
    • Abdo AA, Al-Ahdal MN, Khalid SS etal. IL28B polymorphisms predict the virological response to standard therapy in patients with chronic hepatitis C virus genotype 4 infection. Hepatol. Int. 2013; 7: 533-538.
    • (2013) Hepatol. Int. , vol.7 , pp. 533-538
    • Abdo, A.A.1    Al-Ahdal, M.N.2    Khalid, S.S.3
  • 43
    • 84866993157 scopus 로고    scopus 로고
    • IL28B polymorphisms do not predict response to therapy in chronic hepatitis C with HCV genotype 5
    • Antaki N, Bibert S, Kebbewar K etal. IL28B polymorphisms do not predict response to therapy in chronic hepatitis C with HCV genotype 5. Gut 2012; 61: 1640-1641.
    • (2012) Gut , vol.61 , pp. 1640-1641
    • Antaki, N.1    Bibert, S.2    Kebbewar, K.3
  • 44
    • 84878551376 scopus 로고    scopus 로고
    • Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection
    • Seto WK, Tsang OT, Liu K etal. Role of IL28B and inosine triphosphatase polymorphisms in the treatment of chronic hepatitis C virus genotype 6 infection. J. Viral Hepat. 2013; 20: 470-477.
    • (2013) J. Viral Hepat. , vol.20 , pp. 470-477
    • Seto, W.K.1    Tsang, O.T.2    Liu, K.3
  • 45
    • 84902547461 scopus 로고    scopus 로고
    • Strong prediction of virological response to combination therapy by IL28B gene variants rs12979860 and rs8099917 in chronic hepatitis C genotype 4
    • Sep 16 [Epub ahead of print].
    • Ragheb M, Nemr N, Kishk R. Strong prediction of virological response to combination therapy by IL28B gene variants rs12979860 and rs8099917 in chronic hepatitis C genotype 4. Liver Int. 2013 Sep 16; doi: 10.1111/liv.12321 [Epub ahead of print].
    • (2013) Liver Int.
    • Ragheb, M.1    Nemr, N.2    Kishk, R.3
  • 46
    • 0033594380 scopus 로고    scopus 로고
    • Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group
    • Kenny-Walsh E. Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group. N. Engl. J. Med. 1999; 340: 1228-1233.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1228-1233
    • Kenny-Walsh, E.1
  • 47
    • 15844389654 scopus 로고    scopus 로고
    • Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection
    • Conry-Cantilena C, VanRaden M, Gibble J etal. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection. N. Engl. J. Med. 1996; 334: 1691-1696.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1691-1696
    • Conry-Cantilena, C.1    VanRaden, M.2    Gibble, J.3
  • 48
    • 84874606648 scopus 로고    scopus 로고
    • Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts
    • Duggal P, Thio CL, Wojcik GL etal. Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts. Ann. Intern. Med. 2013; 158: 235-245.
    • (2013) Ann. Intern. Med. , vol.158 , pp. 235-245
    • Duggal, P.1    Thio, C.L.2    Wojcik, G.L.3
  • 49
    • 77957965687 scopus 로고    scopus 로고
    • Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection
    • Grebely J, Petoumenos K, Hellard M etal. Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection. Hepatology 2010; 52: 1216-1224.
    • (2010) Hepatology , vol.52 , pp. 1216-1224
    • Grebely, J.1    Petoumenos, K.2    Hellard, M.3
  • 50
    • 78049469161 scopus 로고    scopus 로고
    • A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice
    • 92 e1.
    • Tillmann HL, Thompson AJ, Patel K etal. A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice. Gastroenterology 2010; 139: 1586-1592, 92 e1.
    • (2010) Gastroenterology , vol.139 , pp. 1586-1592
    • Tillmann, H.L.1    Thompson, A.J.2    Patel, K.3
  • 51
    • 84894634227 scopus 로고    scopus 로고
    • The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C Virus infection
    • Grebely J, Page K, Sacks-Davis R etal. The effects of female sex, viral genotype, and IL28B genotype on spontaneous clearance of acute hepatitis C Virus infection. Hepatology 2014; 59: 109-120.
    • (2014) Hepatology , vol.59 , pp. 109-120
    • Grebely, J.1    Page, K.2    Sacks-Davis, R.3
  • 53
    • 84880283347 scopus 로고    scopus 로고
    • Treatment optimization and prediction of HCV clearance in patients with acute HCV infection
    • Mangia A, Santoro R, Copetti M etal. Treatment optimization and prediction of HCV clearance in patients with acute HCV infection. J. Hepatol. 2013; 59: 221-228.
    • (2013) J. Hepatol. , vol.59 , pp. 221-228
    • Mangia, A.1    Santoro, R.2    Copetti, M.3
  • 54
    • 79952695203 scopus 로고    scopus 로고
    • IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC
    • Fabris C, Falleti E, Cussigh A etal. IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC. J. Hepatol. 2011; 54: 716-722.
    • (2011) J. Hepatol. , vol.54 , pp. 716-722
    • Fabris, C.1    Falleti, E.2    Cussigh, A.3
  • 55
    • 77955852095 scopus 로고    scopus 로고
    • Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients
    • Abe H, Ochi H, Maekawa T etal. Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients. J. Hepatol. 2010; 53: 439-443.
    • (2010) J. Hepatol. , vol.53 , pp. 439-443
    • Abe, H.1    Ochi, H.2    Maekawa, T.3
  • 56
    • 84887018505 scopus 로고    scopus 로고
    • Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: a longitudinal analysis
    • Noureddin M, Wright EC, Alter H etal. Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: a longitudinal analysis. Hepatology 2013; 58: 1548-1557.
    • (2013) Hepatology , vol.58 , pp. 1548-1557
    • Noureddin, M.1    Wright, E.C.2    Alter, H.3
  • 57
    • 79956188487 scopus 로고    scopus 로고
    • Influence of interleukin-28B single-nucleotide polymorphisms on progression to liver cirrhosis in human immunodeficiency virus-hepatitis C virus-coinfected patients receiving antiretroviral therapy
    • Barreiro P, Pineda JA, Rallon N etal. Influence of interleukin-28B single-nucleotide polymorphisms on progression to liver cirrhosis in human immunodeficiency virus-hepatitis C virus-coinfected patients receiving antiretroviral therapy. J. Infect. Dis. 2011; 203: 1629-1636.
    • (2011) J. Infect. Dis. , vol.203 , pp. 1629-1636
    • Barreiro, P.1    Pineda, J.A.2    Rallon, N.3
  • 58
    • 84856380143 scopus 로고    scopus 로고
    • IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes
    • Bochud PY, Bibert S, Kutalik Z etal. IL28B alleles associated with poor hepatitis C virus (HCV) clearance protect against inflammation and fibrosis in patients infected with non-1 HCV genotypes. Hepatology 2012; 55: 384-394.
    • (2012) Hepatology , vol.55 , pp. 384-394
    • Bochud, P.Y.1    Bibert, S.2    Kutalik, Z.3
  • 59
    • 80053308776 scopus 로고    scopus 로고
    • Genetic variation in the interleukin-28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection
    • Marabita F, Aghemo A, De Nicola S etal. Genetic variation in the interleukin-28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection. Hepatology 2011; 54: 1127-1134.
    • (2011) Hepatology , vol.54 , pp. 1127-1134
    • Marabita, F.1    Aghemo, A.2    De Nicola, S.3
  • 60
    • 84870482132 scopus 로고    scopus 로고
    • Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis
    • Akuta N, Suzuki F, Seko Y etal. Complicated relationships of amino acid substitution in hepatitis C virus core region and IL28B genotype influencing hepatocarcinogenesis. Hepatology 2012; 56: 2134-2141.
    • (2012) Hepatology , vol.56 , pp. 2134-2141
    • Akuta, N.1    Suzuki, F.2    Seko, Y.3
  • 61
    • 84862844593 scopus 로고    scopus 로고
    • Analysis of viral amino acids sequences and the IL28B SNP influencing the development of hepatocellular carcinoma in chronic hepatitis C
    • Miura M, Maekawa S, Kadokura M etal. Analysis of viral amino acids sequences and the IL28B SNP influencing the development of hepatocellular carcinoma in chronic hepatitis C. Hepatol. Int. 2012; 6: 386-396.
    • (2012) Hepatol. Int. , vol.6 , pp. 386-396
    • Miura, M.1    Maekawa, S.2    Kadokura, M.3
  • 62
    • 84857118295 scopus 로고    scopus 로고
    • Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection
    • Joshita S, Umemura T, Katsuyama Y etal. Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection. Hum. Immunol. 2012; 73: 298-300.
    • (2012) Hum. Immunol. , vol.73 , pp. 298-300
    • Joshita, S.1    Umemura, T.2    Katsuyama, Y.3
  • 63
    • 84905368327 scopus 로고    scopus 로고
    • Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C
    • Jul 17 [Epub ahead of print].
    • Asahina Y, Tsuchiya K, Nishimura T etal. Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C. J. Gastroenterol. 2013 Jul 17: doi: 10.1007/S00535-013-0858-2 [Epub ahead of print].
    • (2013) J. Gastroenterol.
    • Asahina, Y.1    Tsuchiya, K.2    Nishimura, T.3
  • 64
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR etal. Boceprevir for untreated chronic HCV genotype 1 infection. N. Engl. J. Med. 2011; 364: 1195-1206.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 1195-1206
    • Poordad, F.1    McCone Jr, J.2    Bacon, B.R.3
  • 65
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E etal. Boceprevir for previously treated chronic HCV genotype 1 infection. N. Engl. J. Med. 2011; 364: 1207-1217.
    • (2011) N. Engl. J. Med. , vol.364 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 66
    • 79960720423 scopus 로고    scopus 로고
    • Telaprevir substantially improved SVR rates across all IL28B genotypes in the ADVANCE trial
    • Jacobson IM, Catlett I, Marcellin P etal. Telaprevir substantially improved SVR rates across all IL28B genotypes in the ADVANCE trial. J. Hepatol. 2011; 54 (Suppl. 1): S542.
    • (2011) J. Hepatol. , vol.54 , pp. S542
    • Jacobson, I.M.1    Catlett, I.2    Marcellin, P.3
  • 67
    • 79960447952 scopus 로고    scopus 로고
    • Similar SVR rates in IL28B CC, CT or TT prior relapser, partial or null-responder patients treated with telaprevir/peginterferon/ribavirin: retrospective analysis of the REALIZE study
    • Pol S, Aerssens J, Zeuzem S etal. Similar SVR rates in IL28B CC, CT or TT prior relapser, partial or null-responder patients treated with telaprevir/peginterferon/ribavirin: retrospective analysis of the REALIZE study. J. Hepatol. 2011; 54 (Suppl. 1): S6.
    • (2011) J. Hepatol. , vol.54 , pp. S6
    • Pol, S.1    Aerssens, J.2    Zeuzem, S.3
  • 68
    • 77955691994 scopus 로고    scopus 로고
    • Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin
    • Akuta N, Suzuki F, Hirakawa M etal. Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin. Hepatology 2010; 52: 421-429.
    • (2010) Hepatology , vol.52 , pp. 421-429
    • Akuta, N.1    Suzuki, F.2    Hirakawa, M.3
  • 69
    • 84888295678 scopus 로고    scopus 로고
    • Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-Naive genotype 1 hepatitis C: the randomized PILLAR study
    • Fried MW, Buti M, Dore GJ etal. Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-Naive genotype 1 hepatitis C: the randomized PILLAR study. Hepatology 2013; 58: 1918-1929.
    • (2013) Hepatology , vol.58 , pp. 1918-1929
    • Fried, M.W.1    Buti, M.2    Dore, G.J.3
  • 70
    • 84878992253 scopus 로고    scopus 로고
    • Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naive patients with chronic genotype 1 HCV: SILEN-C1 trial
    • Sulkowski MS, Asselah T, Lalezari J etal. Faldaprevir combined with pegylated interferon alfa-2a and ribavirin in treatment-naive patients with chronic genotype 1 HCV: SILEN-C1 trial. Hepatology 2013; 57: 2143-2154.
    • (2013) Hepatology , vol.57 , pp. 2143-2154
    • Sulkowski, M.S.1    Asselah, T.2    Lalezari, J.3
  • 71
    • 77950817619 scopus 로고    scopus 로고
    • Telaprevir for previously treated chronic HCV infection
    • McHutchison JG, Manns MP, Muir AJ etal. Telaprevir for previously treated chronic HCV infection. N. Engl. J. Med. 2010; 362: 1292-1303.
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1292-1303
    • McHutchison, J.G.1    Manns, M.P.2    Muir, A.J.3
  • 72
    • 84877049762 scopus 로고    scopus 로고
    • Role of interleukin-28B polymorphism as a predictor of sustained virological response in patients with chronic hepatitis C treated with triple therapy: a systematic review and meta-analysis
    • Bota S, Sporea I, Sirli R, Neghina AM, Popescu A, Strain M. Role of interleukin-28B polymorphism as a predictor of sustained virological response in patients with chronic hepatitis C treated with triple therapy: a systematic review and meta-analysis. Clin. Drug Investig. 2013; 33: 325-331.
    • (2013) Clin. Drug Investig. , vol.33 , pp. 325-331
    • Bota, S.1    Sporea, I.2    Sirli, R.3    Neghina, A.M.4    Popescu, A.5    Strain, M.6
  • 73
    • 84879189258 scopus 로고    scopus 로고
    • A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment
    • Lawitz E, Rodriguez-Torres M, Stoehr A etal. A phase 2B study of MK-7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment. J. Hepatol. 2013; 59: 11-17.
    • (2013) J. Hepatol. , vol.59 , pp. 11-17
    • Lawitz, E.1    Rodriguez-Torres, M.2    Stoehr, A.3
  • 74
    • 84856159009 scopus 로고    scopus 로고
    • Preliminary study of two antiviral agents for hepatitis C genotype 1
    • Lok AS, Gardiner DF, Lawitz E etal. Preliminary study of two antiviral agents for hepatitis C genotype 1. N. Engl. J. Med. 2012; 366: 216-224.
    • (2012) N. Engl. J. Med. , vol.366 , pp. 216-224
    • Lok, A.S.1    Gardiner, D.F.2    Lawitz, E.3
  • 75
    • 84857395452 scopus 로고    scopus 로고
    • Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders
    • Chayama K, Takahashi S, Toyota J etal. Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders. Hepatology 2012; 55: 742-748.
    • (2012) Hepatology , vol.55 , pp. 742-748
    • Chayama, K.1    Takahashi, S.2    Toyota, J.3
  • 76
    • 84859412455 scopus 로고    scopus 로고
    • Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C
    • Chu TW, Kulkarni R, Gane EJ etal. Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C. Gastroenterology 2012; 142: 790-795.
    • (2012) Gastroenterology , vol.142 , pp. 790-795
    • Chu, T.W.1    Kulkarni, R.2    Gane, E.J.3
  • 77
    • 84881405876 scopus 로고    scopus 로고
    • Faldaprevir and deleobuvir for HCV genotype 1 infection
    • Zeuzem S, Soriano V, Asselah T etal. Faldaprevir and deleobuvir for HCV genotype 1 infection. N. Engl. J. Med. 2013; 369: 630-639.
    • (2013) N. Engl. J. Med. , vol.369 , pp. 630-639
    • Zeuzem, S.1    Soriano, V.2    Asselah, T.3
  • 78
    • 0037243222 scopus 로고    scopus 로고
    • IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex
    • Kotenko SV, Gallagher G, Baurin VV etal. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat. Immunol. 2003; 4: 69-77.
    • (2003) Nat. Immunol. , vol.4 , pp. 69-77
    • Kotenko, S.V.1    Gallagher, G.2    Baurin, V.V.3
  • 79
    • 0037236826 scopus 로고    scopus 로고
    • IL-28, IL-29 and their class II cytokine receptor IL-28R
    • Sheppard P, Kindsvogel W, Xu W etal. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat. Immunol. 2003; 4: 63-68.
    • (2003) Nat. Immunol. , vol.4 , pp. 63-68
    • Sheppard, P.1    Kindsvogel, W.2    Xu, W.3
  • 81
    • 36348960622 scopus 로고    scopus 로고
    • Hepatic gene expression during treatment with peginterferon and ribavirin: identifying molecular pathways for treatment response
    • Feld JJ, Nanda S, Huang Y etal. Hepatic gene expression during treatment with peginterferon and ribavirin: identifying molecular pathways for treatment response. Hepatology 2007; 46: 1548-1563.
    • (2007) Hepatology , vol.46 , pp. 1548-1563
    • Feld, J.J.1    Nanda, S.2    Huang, Y.3
  • 82
    • 77955475888 scopus 로고    scopus 로고
    • Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C
    • Honda M, Sakai A, Yamashita T etal. Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C. Gastroenterology 2010; 139: 499-509.
    • (2010) Gastroenterology , vol.139 , pp. 499-509
    • Honda, M.1    Sakai, A.2    Yamashita, T.3
  • 83
    • 78649608515 scopus 로고    scopus 로고
    • IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C
    • Urban TJ, Thompson AJ, Bradrick SS etal. IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C. Hepatology 2010; 52: 1888-1896.
    • (2010) Hepatology , vol.52 , pp. 1888-1896
    • Urban, T.J.1    Thompson, A.J.2    Bradrick, S.S.3
  • 84
    • 42949143122 scopus 로고    scopus 로고
    • Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response
    • Asahina Y, Izumi N, Hirayama I etal. Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response. Gastroenterology 2008; 134: 1396-1405.
    • (2008) Gastroenterology , vol.134 , pp. 1396-1405
    • Asahina, Y.1    Izumi, N.2    Hirayama, I.3
  • 85
    • 84155186277 scopus 로고    scopus 로고
    • Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response
    • Asahina Y, Tsuchiya K, Muraoka M etal. Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response. Hepatology 2012; 55: 20-29.
    • (2012) Hepatology , vol.55 , pp. 20-29
    • Asahina, Y.1    Tsuchiya, K.2    Muraoka, M.3
  • 86
    • 79956147625 scopus 로고    scopus 로고
    • IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy
    • Abe H, Hayes CN, Ochi H etal. IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy. J. Hepatol. 2011; 54: 1094-1101.
    • (2011) J. Hepatol. , vol.54 , pp. 1094-1101
    • Abe, H.1    Hayes, C.N.2    Ochi, H.3
  • 87
    • 84862777861 scopus 로고    scopus 로고
    • HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons
    • Thomas E, Gonzalez VD, Li Q etal. HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons. Gastroenterology 2012; 142: 978-988.
    • (2012) Gastroenterology , vol.142 , pp. 978-988
    • Thomas, E.1    Gonzalez, V.D.2    Li, Q.3
  • 88
    • 84881544361 scopus 로고    scopus 로고
    • Hepatitis C virus kinetics by administration of pegylated interferon-alpha in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene
    • Watanabe T, Sugauchi F, Tanaka Y etal. Hepatitis C virus kinetics by administration of pegylated interferon-alpha in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene. Gut 2013; 62: 1340-1346.
    • (2013) Gut , vol.62 , pp. 1340-1346
    • Watanabe, T.1    Sugauchi, F.2    Tanaka, Y.3
  • 89
    • 84881517083 scopus 로고    scopus 로고
    • Human type 2 myeloid dendritic cells produce interferon-lambda and amplify interferon-alpha in response to hepatitis C virus infection
    • e7.
    • Zhang S, Kodys K, Li K, Szabo G. Human type 2 myeloid dendritic cells produce interferon-lambda and amplify interferon-alpha in response to hepatitis C virus infection. Gastroenterology 2013; 144: 414-425 e7.
    • (2013) Gastroenterology , vol.144 , pp. 414-425
    • Zhang, S.1    Kodys, K.2    Li, K.3    Szabo, G.4
  • 90
    • 84876700100 scopus 로고    scopus 로고
    • Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-lambda in response to hepatitis C virus
    • Yoshio S, Kanto T, Kuroda S etal. Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-lambda in response to hepatitis C virus. Hepatology 2013; 57: 1705-1715.
    • (2013) Hepatology , vol.57 , pp. 1705-1715
    • Yoshio, S.1    Kanto, T.2    Kuroda, S.3
  • 91
    • 84873083416 scopus 로고    scopus 로고
    • A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
    • Prokunina-Olsson L, Muchmore B, Tang W etal. A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat. Genet. 2013; 45: 164-171.
    • (2013) Nat. Genet. , vol.45 , pp. 164-171
    • Prokunina-Olsson, L.1    Muchmore, B.2    Tang, W.3
  • 92
    • 84880688112 scopus 로고    scopus 로고
    • IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction
    • Bibert S, Roger T, Calandra T etal. IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction. J. Exp. Med. 2013; 210: 1109-1116.
    • (2013) J. Exp. Med. , vol.210 , pp. 1109-1116
    • Bibert, S.1    Roger, T.2    Calandra, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.