Fast liquid chromatographic-tandem mass spectrometric method using mixed-mode phase chromatography and solid phase extraction for the determination of 12 mono-hydroxylated brominated diphenyl ethers in human serum

Journal of Chromatography A

Volumn 1356, Issue , 2014, Pages 138-147

  Petropoulou, Syrago Styliani E ^a   Duong, Wendy ^a   Petreas, Myrto ^a   Park, June Soo ^a  

^a Environmental Chemistry Laboratory Department of Toxic Substances Control ^*  (United States)

Author keywords

Enzymatic hydrolysis; Human serum; Liquid chromatography mass spectrometry; Mixed mode chromatography; OH PBDEs; Solid phase extraction

Indexed keywords

BODY FLUIDS; COLUMN CHROMATOGRAPHY; ENZYMATIC HYDROLYSIS; HYDROXYLATION; LIQUID CHROMATOGRAPHY; PHASE SEPARATION;

HUMAN SERUM; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MIXED-MODE CHROMATOGRAPHY; OH-PBDES; SOLID-PHASE EXTRACTION;

ORGANIC POLLUTANTS;

2' HYDROXY 2,3',4,5' TETRABROMODIPHENYL ETHER; 3 HYDROXY 2,2',4,4' TETRABROMODIPHENYL ETHER; 3 HYDROXY 2,2',4,4',6 PENTABROMODIPHENYL ETHER; 4 HYDROXY 2,2',3,4' TETRABROMODIPHENYL ETHER; 4 HYDROXY 2,2',3,4',5 PENTABROMODIPHENYL ETHER; 4' HYDROXY 2,2',4 TRIBROMODIPHENYL ETHER; 4' HYDROXY 2,2',4,5' TETRABROMODIPHENYL ETHER; 4' HYDROXY 2,2',4,5,5' PENTABROMODIPHENYL ETHER; 5 HYDROXY 2,2',4,4' TETRABROMODIPHENYL ETHER; 5' HYDROXY 2,2',4,4',5 PENTABROMODIPHENYL ETHER; 6 HYDROXY 2,2',4,4' TETRABROMODIPHENYL ETHER; 6' HYDROXY 2,2',4,4',5 PENTABROMODIPHENYL ETHER; POLYBROMINATED DIPHENYL ETHER; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BLOOD SAMPLING; HUMAN; HYDROLYSIS; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LINEAR SYSTEM; LIQUID CHROMATOGRAPHY; MIXED MODE PHASE CHROMATOGRAPHY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

MUS; RATTUS;

ENZYMATIC HYDROLYSIS; HUMAN SERUM; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MIXED-MODE CHROMATOGRAPHY; OH-PBDES; SOLID PHASE EXTRACTION;

CHROMATOGRAPHY, ION EXCHANGE; HALOGENATED DIPHENYL ETHERS; HUMANS; HYDROLYSIS; LIMIT OF DETECTION; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84907274166     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.06.048     Document Type: Article

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