The 2,2',4,4'-tetrabromodiphenyl ether hydroxylated metabolites 5-OH-BDE-47 and 6-OH-BDE-47 stimulate estradiol secretion in the ovary by activating aromatase expression

Toxicology

Volumn 305, Issue , 2013, Pages 65-70

  Karpeta, Anna ^a   Barc, Justyna ^a   Ptak, Anna ^a   Gregoraszczuk, Ewa L ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

5 OH BDE 47; 6 OH BDE 47; Aromatase; Estradiol; Ovary

Indexed keywords

2,2',4,4' TETRABROMODIPHENYL ETHER; 5 HYDROXY 2,2',4,4' TETRABROMODIPHENYL ETHER; 6 HYDROXY 2,2',4,4' TETRABROMODIPHENYL ETHER; ANDROSTENEDIONE; AROMATASE; ESTRADIOL; FADROZOLE; FLUORESCEIN; POLYBROMINATED DIPHENYL ETHER; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ESTROGEN RELEASE; FEMALE; GENE EXPRESSION; HYDROXYLATION; NONHUMAN; OVARY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEROID HYDROXYLATION; STEROIDOGENESIS;

ACTINS; ANIMALS; AROMATASE; BLOTTING, WESTERN; CELLS, CULTURED; ENDOCRINE DISRUPTORS; ENZYME ACTIVATION; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANULOSA CELLS; OVARIAN FOLLICLE; OVARY; POLYBROMINATED BIPHENYLS; REAL-TIME POLYMERASE CHAIN REACTION; STEROIDS; SWINE; TESTOSTERONE; THECA CELLS;

EID: 84873963632     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.10.021     Document Type: Article

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