Glucuronidation of hydroxylated polybrominated diphenyl ethers and their modulation of estrogen UDP-glucuronosyltransferases

Chemosphere

Volumn 86, Issue 7, 2012, Pages 727-734

  Lai, Yongquan ^a   Lu, Minghua ^a   Lin, Shuhai ^a   Cai, Zongwei ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

17 Estradiol; Glucuronidation modulation; Hydroxylated polybrominated diphenyl ethers; Structure activity relationship

Indexed keywords

ATOMS; BIOCHEMISTRY; BROMINE; ETHERS; HYDROXYLATION; METABOLITES; MODULATION;

GLUCURONIDATION MODULATIONS; HYDROXYLATED METABOLITES; HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS; INTER-INDIVIDUAL DIFFERENCES; NONCOMPETITIVE INHIBITIONS; PHENOLIC HYDROXYL GROUP; POLYBROMINATED DIPHENYL ETHER (PBDES); STRUCTURE ACTIVITY RELATIONSHIPS;

ORGANIC POLLUTANTS;

BROMINE; ESTRADIOL; ESTROGEN; GLUCURONOSYLTRANSFERASE; HYDROXYL GROUP; PHENOL; POLYBROMINATED DIPHENYL ETHER; TRICLOSAN; URIDINE DIPHOSPHATE;

BIOAVAILABILITY; BROMINE; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; ESTROGENIC COMPOUND; ETHER; HYDROXYL RADICAL; INHIBITION; METABOLISM; METABOLITE; MICROCOSM; PHENOLIC COMPOUND; POTASSIUM; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ESTRADIOL BLOOD LEVEL; GLUCURONIDATION; IC 50; KINETICS; LIVER MICROSOME; MALE; METABOLIC RATE; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; TARGET ORGAN;

RATTUS;

EID: 84856052508     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2011.10.047     Document Type: Article

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