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Volumn 14, Issue 1, 2014, Pages

Acupuncture stimulation improves scopolamine-induced cognitive impairment via activation of cholinergic system and regulation of BDNF and CREB expressions in rats

Author keywords

Brain derived neurotrophic factor; cAMP response element binding protein; Cholinergic neurons; Memory; Scopolamine

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CARRIER PROTEIN; CHOLINE ACETYLTRANSFERASE; CHOLINE TRANSPORTER 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; SCOPOLAMINE; UNCLASSIFIED DRUG; VESICULAR ACETYLCHOLINE TRANSPORTER; SCOPOLAMINE BROMIDE;

EID: 84907271947     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-14-338     Document Type: Article
Times cited : (80)

References (61)
  • 1
    • 0042020173 scopus 로고    scopus 로고
    • Treatment of Alzheimer's disease: current status and new perspectives
    • 12941576
    • Scarpini E, Scheltens P, Feldman H. Treatment of Alzheimer's disease: current status and new perspectives. Lancet Neurol 2003, 2(9):539-547. 10.1016/S1474-4422(03)00502-7, 12941576.
    • (2003) Lancet Neurol , vol.2 , Issue.9 , pp. 539-547
    • Scarpini, E.1    Scheltens, P.2    Feldman, H.3
  • 2
    • 33751235837 scopus 로고    scopus 로고
    • The role of acetylcholine in learning and memory
    • 2659740, 17011181
    • Hasselmo ME. The role of acetylcholine in learning and memory. Curr Opin Neurobiol 2006, 16(6):710-715. 10.1016/j.conb.2006.09.002, 2659740, 17011181.
    • (2006) Curr Opin Neurobiol , vol.16 , Issue.6 , pp. 710-715
    • Hasselmo, M.E.1
  • 4
    • 77953388318 scopus 로고    scopus 로고
    • Therapy for Alzheimer's disease: how effective are current treatments?
    • 3002627, 21179526
    • Lanctôt KL, Rajaram RD, Herrmann N. Therapy for Alzheimer's disease: how effective are current treatments?. Ther Adv Neurol Disord 2009, 2(3):163-180. 10.1177/1756285609102724, 3002627, 21179526.
    • (2009) Ther Adv Neurol Disord , vol.2 , Issue.3 , pp. 163-180
    • Lanctôt, K.L.1    Rajaram, R.D.2    Herrmann, N.3
  • 5
    • 0037315878 scopus 로고    scopus 로고
    • A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
    • Review, 12558063
    • Lahiri DK, Farlow MR, Sambamurti K, Greig NH, Giacobini E, Schneider LS. A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease. Curr Drug Targets 2003, 4(2):97-112. Review, 10.2174/1389450033346957, 12558063.
    • (2003) Curr Drug Targets , vol.4 , Issue.2 , pp. 97-112
    • Lahiri, D.K.1    Farlow, M.R.2    Sambamurti, K.3    Greig, N.H.4    Giacobini, E.5    Schneider, L.S.6
  • 6
    • 84861035259 scopus 로고    scopus 로고
    • Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats
    • 3339292, 22563252
    • Lee B, Sur B, Shim I, Lee H, Hahm DH. Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats. Korean J Physiol Pharmacol 2012, 16(2):79-89. 10.4196/kjpp.2012.16.2.79, 3339292, 22563252.
    • (2012) Korean J Physiol Pharmacol , vol.16 , Issue.2 , pp. 79-89
    • Lee, B.1    Sur, B.2    Shim, I.3    Lee, H.4    Hahm, D.H.5
  • 7
    • 58349100449 scopus 로고    scopus 로고
    • Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease
    • 18930076
    • Ahmed T, Gilani AH. Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. Pharmacol Biochem Behav 2009, 91(4):554-559. 10.1016/j.pbb.2008.09.010, 18930076.
    • (2009) Pharmacol Biochem Behav , vol.91 , Issue.4 , pp. 554-559
    • Ahmed, T.1    Gilani, A.H.2
  • 8
    • 84867256116 scopus 로고    scopus 로고
    • The cyanine Dye NK-4 improves scopolamine-induced memory impairments in mice
    • 23037173
    • Uchida S, Endo S, Akita K, Ohta T, Fukuda S. The cyanine Dye NK-4 improves scopolamine-induced memory impairments in mice. Biol Pharm Bull 2012, 35(10):1831-1835. 10.1248/bpb.b12-00370, 23037173.
    • (2012) Biol Pharm Bull , vol.35 , Issue.10 , pp. 1831-1835
    • Uchida, S.1    Endo, S.2    Akita, K.3    Ohta, T.4    Fukuda, S.5
  • 9
    • 79954423234 scopus 로고    scopus 로고
    • Gypenoside TN-2 ameliorates scopolamine-induced learning deficit in mice
    • 21333723
    • Hong SW, Yang JH, Joh EH, Kim HJ, Kim DH. Gypenoside TN-2 ameliorates scopolamine-induced learning deficit in mice. J Ethnopharmacol 2011, 134(3):1010-1013. 10.1016/j.jep.2011.02.002, 21333723.
    • (2011) J Ethnopharmacol , vol.134 , Issue.3 , pp. 1010-1013
    • Hong, S.W.1    Yang, J.H.2    Joh, E.H.3    Kim, H.J.4    Kim, D.H.5
  • 10
    • 46749094132 scopus 로고    scopus 로고
    • Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels
    • 18457678
    • Willians CM, El Mohsen MA, Vauzour D, Rendeiro C, Butler LT, Ellis JA, Whiteman M, Spencer JP. Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radic Biol Med 2008, 45(3):295-305. 10.1016/j.freeradbiomed.2008.04.008, 18457678.
    • (2008) Free Radic Biol Med , vol.45 , Issue.3 , pp. 295-305
    • Willians, C.M.1    El Mohsen, M.A.2    Vauzour, D.3    Rendeiro, C.4    Butler, L.T.5    Ellis, J.A.6    Whiteman, M.7    Spencer, J.P.8
  • 11
    • 77955913748 scopus 로고    scopus 로고
    • Memory impairment in cognitively impaired aged rats associated with decreased hippocampal CREB phosphorylation: reversal by procyanidins extracted from the lotus seedpod
    • Xu J, Rong S, Xie B, Sun Z, Deng Q, Wu H, Bao W, Wang D, Yao P, Huang F, Liu L. Memory impairment in cognitively impaired aged rats associated with decreased hippocampal CREB phosphorylation: reversal by procyanidins extracted from the lotus seedpod. J Gerontol A Biol Sci Med Sci 2010, 65(9):933-940.
    • (2010) J Gerontol A Biol Sci Med Sci , vol.65 , Issue.9 , pp. 933-940
    • Xu, J.1    Rong, S.2    Xie, B.3    Sun, Z.4    Deng, Q.5    Wu, H.6    Bao, W.7    Wang, D.8    Yao, P.9    Huang, F.10    Liu, L.11
  • 12
    • 0036742611 scopus 로고    scopus 로고
    • From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning
    • Reveiw, 2806479, 12359832
    • Tyler WJ, Alonso M, Bramham CR, Pozzo-miller LD. From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. Learn Mem 2002, 9(5):224-237. Reveiw, 10.1101/lm.51202, 2806479, 12359832.
    • (2002) Learn Mem , vol.9 , Issue.5 , pp. 224-237
    • Tyler, W.J.1    Alonso, M.2    Bramham, C.R.3    Pozzo-miller, L.D.4
  • 13
    • 84874114021 scopus 로고    scopus 로고
    • Ginsenosides Rg5 and Rh3 protect scopolamine-induced memory deficits in mice
    • 23313392
    • Kim EJ, Jung IH, Van Le TK, Jeong JJ, Kim NJ, Kim DH. Ginsenosides Rg5 and Rh3 protect scopolamine-induced memory deficits in mice. J Ethnopharmacol 2013, 146(1):294-299. 10.1016/j.jep.2012.12.047, 23313392.
    • (2013) J Ethnopharmacol , vol.146 , Issue.1 , pp. 294-299
    • Kim, E.J.1    Jung, I.H.2    Van Le, T.K.3    Jeong, J.J.4    Kim, N.J.5    Kim, D.H.6
  • 15
    • 50649105722 scopus 로고    scopus 로고
    • Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis
    • Kotani S, Yamauchi T, Teramoto T, Ogura H. Donepezil, an acetylcholinesterase inhibitor, enhances adult hippocampal neurogenesis. Chem Biol Interact 2008, 175(1-3):227-230.
    • (2008) Chem Biol Interact , vol.175 , Issue.1-3 , pp. 227-230
    • Kotani, S.1    Yamauchi, T.2    Teramoto, T.3    Ogura, H.4
  • 16
    • 33748760144 scopus 로고    scopus 로고
    • Pharmacological evidence of cholinergic involvement in adult hippocampal neurogenesis in rats
    • Kotani S, Yamauchi T, Teramoto T, Ogura H. Pharmacological evidence of cholinergic involvement in adult hippocampal neurogenesis in rats. Neuroscience 2004, 142(2):505-514.
    • (2004) Neuroscience , vol.142 , Issue.2 , pp. 505-514
    • Kotani, S.1    Yamauchi, T.2    Teramoto, T.3    Ogura, H.4
  • 17
    • 84869029404 scopus 로고    scopus 로고
    • Acute effects of electro-acupuncture (EA) on hippocampal long term potentiation (LTP) of perforant path-dentate gyrus granule cells synapse related to memory
    • He X, Yan T, Chen R, Ran D. Acute effects of electro-acupuncture (EA) on hippocampal long term potentiation (LTP) of perforant path-dentate gyrus granule cells synapse related to memory. Acupunct Electrother Res 2012, 37(2-3):89-101.
    • (2012) Acupunct Electrother Res , vol.37 , Issue.2-3 , pp. 89-101
    • He, X.1    Yan, T.2    Chen, R.3    Ran, D.4
  • 18
    • 4143071207 scopus 로고    scopus 로고
    • Acupuncture decreases neuropeptide Y expression in the hypothalamus of rats with Streptozotocin-induced diabetes
    • Lee JD, Jang MH, Kim EH, Kim CJ. Acupuncture decreases neuropeptide Y expression in the hypothalamus of rats with Streptozotocin-induced diabetes. Acupunct Electrother Res 2004, 29(1-2):73-82.
    • (2004) Acupunct Electrother Res , vol.29 , Issue.1-2 , pp. 73-82
    • Lee, J.D.1    Jang, M.H.2    Kim, E.H.3    Kim, C.J.4
  • 19
    • 82355175436 scopus 로고    scopus 로고
    • Electroacupuncture protected pyramidal cells in hippocampal CA1 region of vascular dementia rats by inhibiting the expression of p53 and Noxa
    • 20950325
    • Zhu Y, Zeng Y. Electroacupuncture protected pyramidal cells in hippocampal CA1 region of vascular dementia rats by inhibiting the expression of p53 and Noxa. CNS Neurosci Ther 2011, 17(6):599-604. 10.1111/j.1755-5949.2010.00192.x, 20950325.
    • (2011) CNS Neurosci Ther , vol.17 , Issue.6 , pp. 599-604
    • Zhu, Y.1    Zeng, Y.2
  • 20
    • 35649003846 scopus 로고    scopus 로고
    • Acupuncture stimulation at Baihui acupoint reduced cerebral infarct and increased dopamine levels in chronic cerebral hypoterfusion and ischemia-reperfusion injured Sprague-Dawley rats
    • 17963318
    • Chunag CM, Hsieh CL, Li TC, Lin JG. Acupuncture stimulation at Baihui acupoint reduced cerebral infarct and increased dopamine levels in chronic cerebral hypoterfusion and ischemia-reperfusion injured Sprague-Dawley rats. Am J Chin Med 2007, 35(5):779-791. 10.1142/S0192415X07005260, 17963318.
    • (2007) Am J Chin Med , vol.35 , Issue.5 , pp. 779-791
    • Chunag, C.M.1    Hsieh, C.L.2    Li, T.C.3    Lin, J.G.4
  • 21
    • 79953272278 scopus 로고    scopus 로고
    • Locating the Acupoint Baihui (GV20) Beneath the Cerebral Cortex with MRI Reconstructed 3D Neuroimages
    • Shen EY, Chen FJ, Chen YY, Lin MF. Locating the Acupoint Baihui (GV20) Beneath the Cerebral Cortex with MRI Reconstructed 3D Neuroimages. Evid Based Complement Alternat Med 2011, 362494.
    • (2011) Evid Based Complement Alternat Med , pp. 362494
    • Shen, E.Y.1    Chen, F.J.2    Chen, Y.Y.3    Lin, M.F.4
  • 22
    • 65649121114 scopus 로고    scopus 로고
    • Acupuncture for Alzheimer's disease: a systematic review
    • 19490197
    • Lee MS, Shin BS, Ernst E. Acupuncture for Alzheimer's disease: a systematic review. Int J Clin Pract 2009, 63(6):874-879. 10.1111/j.1742-1241.2009.02043.x, 19490197.
    • (2009) Int J Clin Pract , vol.63 , Issue.6 , pp. 874-879
    • Lee, M.S.1    Shin, B.S.2    Ernst, E.3
  • 23
    • 83655193410 scopus 로고    scopus 로고
    • Electroacupuncture increased cerebral blood flow and reduced ischemia brain injury: dependence on stimulation intensity and frequency
    • 3233896, 21836043
    • Zhou F, Guo J, Cheng J, Wu G, Xia Y. Electroacupuncture increased cerebral blood flow and reduced ischemia brain injury: dependence on stimulation intensity and frequency. J Appl Physiol 2011, 111(6):1877-1887. 10.1152/japplphysiol.00313.2011, 3233896, 21836043.
    • (2011) J Appl Physiol , vol.111 , Issue.6 , pp. 1877-1887
    • Zhou, F.1    Guo, J.2    Cheng, J.3    Wu, G.4    Xia, Y.5
  • 24
    • 84862965142 scopus 로고    scopus 로고
    • Acupuncture stimulation alleviates corticosterone-induced impairments of spatial memory and cholinergic neurons in rats
    • 3246768, 22216057
    • Lee B, Sur BJ, Kwon S, Jung E, Shim I, Lee H, Hahm DH. Acupuncture stimulation alleviates corticosterone-induced impairments of spatial memory and cholinergic neurons in rats. Evid Based Complement Alternat Med 2012, 2012:670536. 3246768, 22216057.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 670536
    • Lee, B.1    Sur, B.J.2    Kwon, S.3    Jung, E.4    Shim, I.5    Lee, H.6    Hahm, D.H.7
  • 25
    • 84866174502 scopus 로고    scopus 로고
    • Effects of electroacupuncture at head points on the function of cerebral motor areas in stroke patients: A PET study
    • 3432396, 22956979
    • Fang Z, Ning J, Xiong C, Shulin Y. Effects of electroacupuncture at head points on the function of cerebral motor areas in stroke patients: A PET study. Evid Based Complement Alternat Med 2012, 2012:902413. 3432396, 22956979.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 902413
    • Fang, Z.1    Ning, J.2    Xiong, C.3    Shulin, Y.4
  • 26
    • 84856101627 scopus 로고    scopus 로고
    • Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats
    • Wang Q, Wang F, Li X, Yang Q, Li X, Xu N, Huang Y, Zhang Q, Gou X, Chen S, Xiong L. Electroacupuncture pretreatment attenuates cerebral ischemic injury through α7 nicotinic acetylcholine receptor-mediated inhibition of high-mobility group box 1 release in rats. J Neuroinflammation 2012, 26(9):24-36.
    • (2012) J Neuroinflammation , vol.26 , Issue.9 , pp. 24-36
    • Wang, Q.1    Wang, F.2    Li, X.3    Yang, Q.4    Li, X.5    Xu, N.6    Huang, Y.7    Zhang, Q.8    Gou, X.9    Chen, S.10    Xiong, L.11
  • 27
    • 84907273117 scopus 로고    scopus 로고
    • Hepatoprotective effects of elector-acupuncture at Taechung (LR3) and Yangji (TE4) on experimental liver injury in rats
    • Youn D, Na C. Hepatoprotective effects of elector-acupuncture at Taechung (LR3) and Yangji (TE4) on experimental liver injury in rats. Korean J Acupunct 2006, 23(2):167-176.
    • (2006) Korean J Acupunct , vol.23 , Issue.2 , pp. 167-176
    • Youn, D.1    Na, C.2
  • 28
    • 31744444320 scopus 로고    scopus 로고
    • Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats
    • 16289320
    • Zhao RJ, Yoon SS, Lee BH, Kwon YK, Kim KJ, Shim I, Choi KH, Kim MR, Golden GT, Yang CH. Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats. Neurosci Lett 2006, 395(1):28-32. 10.1016/j.neulet.2005.10.043, 16289320.
    • (2006) Neurosci Lett , vol.395 , Issue.1 , pp. 28-32
    • Zhao, R.J.1    Yoon, S.S.2    Lee, B.H.3    Kwon, Y.K.4    Kim, K.J.5    Shim, I.6    Choi, K.H.7    Kim, M.R.8    Golden, G.T.9    Yang, C.H.10
  • 30
    • 84862116088 scopus 로고    scopus 로고
    • Inhibition of glutamate and acetylcholine release in behavioral improvement induced by electroacupuncture in parkinsonian rats
    • 22583765
    • Sun Z, Jia J, Gong X, Jia Y, Deng J, Wang X, Wang X. Inhibition of glutamate and acetylcholine release in behavioral improvement induced by electroacupuncture in parkinsonian rats. Neurosci Lett 2012, 520(1):32-37. 10.1016/j.neulet.2012.05.021, 22583765.
    • (2012) Neurosci Lett , vol.520 , Issue.1 , pp. 32-37
    • Sun, Z.1    Jia, J.2    Gong, X.3    Jia, Y.4    Deng, J.5    Wang, X.6    Wang, X.7
  • 31
    • 78249285920 scopus 로고    scopus 로고
    • Electroacupuncture at Baihui acupoint (GV20) reverses behavior deficit and long-term potentiation through N-methyl-d-aspartate and transient receptor potential vanilloid subtype 1 receptors in middle cerebral artery occlusion rats
    • 21064218
    • Lin YW, Hsieh CL. Electroacupuncture at Baihui acupoint (GV20) reverses behavior deficit and long-term potentiation through N-methyl-d-aspartate and transient receptor potential vanilloid subtype 1 receptors in middle cerebral artery occlusion rats. J Integr Neurosci 2010, 9(3):269-282. 10.1142/S0219635210002433, 21064218.
    • (2010) J Integr Neurosci , vol.9 , Issue.3 , pp. 269-282
    • Lin, Y.W.1    Hsieh, C.L.2
  • 32
    • 67651115739 scopus 로고    scopus 로고
    • Acute effects of acupuncture treatment with baihui (GV20) on human arterial stiffness andwave reflection
    • 20633484
    • Satoh H. Acute effects of acupuncture treatment with baihui (GV20) on human arterial stiffness andwave reflection. J Acupunct Meridian Stud 2009, 2(2):130-134. 10.1016/S2005-2901(09)60045-5, 20633484.
    • (2009) J Acupunct Meridian Stud , vol.2 , Issue.2 , pp. 130-134
    • Satoh, H.1
  • 33
    • 78649772524 scopus 로고    scopus 로고
    • Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus
    • 20622480
    • Hwang IK, Chung JY, Yoo DY, Yi SS, Youn HY, Seong JK, Yoon YS. Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus. J Vet Med Sci 2010, 72(11):1431-1436. 10.1292/jvms.09-0527, 20622480.
    • (2010) J Vet Med Sci , vol.72 , Issue.11 , pp. 1431-1436
    • Hwang, I.K.1    Chung, J.Y.2    Yoo, D.Y.3    Yi, S.S.4    Youn, H.Y.5    Seong, J.K.6    Yoon, Y.S.7
  • 34
    • 68149124327 scopus 로고    scopus 로고
    • Acupuncture stimulation improves balance function in stroke patients: a single-blinded controlled, randomized study
    • 19606509
    • Liu SY, Hsieh CL, Wei TS, Liu PT, Chang YJ, Li TC. Acupuncture stimulation improves balance function in stroke patients: a single-blinded controlled, randomized study. Am J Chin Med 2009, 37(3):483-494. 10.1142/S0192415X09006990, 19606509.
    • (2009) Am J Chin Med , vol.37 , Issue.3 , pp. 483-494
    • Liu, S.Y.1    Hsieh, C.L.2    Wei, T.S.3    Liu, P.T.4    Chang, Y.J.5    Li, T.C.6
  • 35
    • 27744448895 scopus 로고    scopus 로고
    • Acupuncture improved cognitive impairment caused by multi-infarct dementia in rats
    • 16181648
    • Yu J, Liu C, Zhang X, Han J. Acupuncture improved cognitive impairment caused by multi-infarct dementia in rats. Physiol Behav 2005, 86(4):434-441. 10.1016/j.physbeh.2005.07.015, 16181648.
    • (2005) Physiol Behav , vol.86 , Issue.4 , pp. 434-441
    • Yu, J.1    Liu, C.2    Zhang, X.3    Han, J.4
  • 36
    • 84873934186 scopus 로고    scopus 로고
    • Electroacupuncture Acutely Improves Cerebral Blood Flow and Attenuates Moderate Ischemic Injury via an Endothelial Mechanism in Mice
    • 3572074, 23418594
    • Kim JH, Choi KH, Jang YJ, Bae SS, Shin BC, Choi BT, Shin HK. Electroacupuncture Acutely Improves Cerebral Blood Flow and Attenuates Moderate Ischemic Injury via an Endothelial Mechanism in Mice. PLoS One 2013, 8(2):e56736. 10.1371/journal.pone.0056736, 3572074, 23418594.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e56736
    • Kim, J.H.1    Choi, K.H.2    Jang, Y.J.3    Bae, S.S.4    Shin, B.C.5    Choi, B.T.6    Shin, H.K.7
  • 38
    • 77954086949 scopus 로고    scopus 로고
    • The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies
    • 20398692
    • Klinkenberg I, Blokland A. The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies. Neurosci Biobehav Rev 2010, 34(8):1307-1350. 10.1016/j.neubiorev.2010.04.001, 20398692.
    • (2010) Neurosci Biobehav Rev , vol.34 , Issue.8 , pp. 1307-1350
    • Klinkenberg, I.1    Blokland, A.2
  • 39
    • 84870056306 scopus 로고    scopus 로고
    • Effects of chronic scopolamine administration on spatial working memory and hippocampal receptors related to learning
    • 23080310
    • Doguc DK, Delibas N, Vural H, Altuntas I, Sutcu R, Sonmez Y. Effects of chronic scopolamine administration on spatial working memory and hippocampal receptors related to learning. Behav Pharmacol 2012, 23(8):762-770. 10.1097/FBP.0b013e32835a38af, 23080310.
    • (2012) Behav Pharmacol , vol.23 , Issue.8 , pp. 762-770
    • Doguc, D.K.1    Delibas, N.2    Vural, H.3    Altuntas, I.4    Sutcu, R.5    Sonmez, Y.6
  • 40
    • 84858969795 scopus 로고    scopus 로고
    • Scopolamine induced memory impairment; possible involvement of NMDA receptor mechanisms of dorsal hippocampus and/or septum
    • Khakpai F, Nasehi M, Haeri-Rohani A, Eidi A, Zarrindast MR. Scopolamine induced memory impairment; possible involvement of NMDA receptor mechanisms of dorsal hippocampus and/or septum. Behav Brain Res 2012, 213(1):1-10.
    • (2012) Behav Brain Res , vol.213 , Issue.1 , pp. 1-10
    • Khakpai, F.1    Nasehi, M.2    Haeri-Rohani, A.3    Eidi, A.4    Zarrindast, M.R.5
  • 41
    • 0036050824 scopus 로고    scopus 로고
    • Long term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer's disease
    • 12456062
    • Giacobini E. Long term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer's disease. J Neural Transm Suppl 2002, 62:181-187. 10.1007/978-3-7091-6139-5_17, 12456062.
    • (2002) J Neural Transm Suppl , vol.62 , pp. 181-187
    • Giacobini, E.1
  • 42
    • 79955715083 scopus 로고    scopus 로고
    • The cholinergic system, circadian rhythmicity, and time memory
    • 21115064
    • Hut RA, Van der Zee EA. The cholinergic system, circadian rhythmicity, and time memory. Behav Brain Res 2011, 221(2):466-480. 10.1016/j.bbr.2010.11.039, 21115064.
    • (2011) Behav Brain Res , vol.221 , Issue.2 , pp. 466-480
    • Hut, R.A.1    Van der Zee, E.A.2
  • 43
    • 0036728917 scopus 로고    scopus 로고
    • Memory deficits in Alzheimer's disease: the encoding hypothesis and cholinergic function
    • Review, 12412885
    • White KG, Ruske AC. Memory deficits in Alzheimer's disease: the encoding hypothesis and cholinergic function. Psychon Bull Rev 2002, 9(3):426-437. Review, 10.3758/BF03196301, 12412885.
    • (2002) Psychon Bull Rev , vol.9 , Issue.3 , pp. 426-437
    • White, K.G.1    Ruske, A.C.2
  • 44
    • 77955050874 scopus 로고    scopus 로고
    • Krill phosphatidylserine improves learning and memory in Morris water maze in aged rats
    • 20677367
    • Lee B, Sur BJ, Han JJ, Shim I, Her S, Lee HJ, Hahm DH. Krill phosphatidylserine improves learning and memory in Morris water maze in aged rats. Prog Neuropsychopharmacol Biol Psychiatry 2010, 34(6):1085-1093. 10.1016/j.pnpbp.2010.05.031, 20677367.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , Issue.6 , pp. 1085-1093
    • Lee, B.1    Sur, B.J.2    Han, J.J.3    Shim, I.4    Her, S.5    Lee, H.J.6    Hahm, D.H.7
  • 45
    • 11144243802 scopus 로고    scopus 로고
    • Choline transporters, cholinergic transmission and cognition
    • 15611726
    • Sarter M, Parikh V. Choline transporters, cholinergic transmission and cognition. Nat Rev Neurosci 2005, 6(1):48-56. 10.1038/nrn1588, 15611726.
    • (2005) Nat Rev Neurosci , vol.6 , Issue.1 , pp. 48-56
    • Sarter, M.1    Parikh, V.2
  • 48
    • 84863780825 scopus 로고    scopus 로고
    • Overexpression of the vesicular acetylcholine transporter increased acetylcholine release in the hippocampus
    • Nagy PM, Aubert I. Overexpression of the vesicular acetylcholine transporter increased acetylcholine release in the hippocampus. Neuroscience 2012, 30(218):1-11.
    • (2012) Neuroscience , vol.30 , Issue.218 , pp. 1-11
    • Nagy, P.M.1    Aubert, I.2
  • 49
    • 84864748526 scopus 로고    scopus 로고
    • Intraperitoneal injection of saline modulates hippocampal brain receptor complex levels but does not impair performance in the Morris Water Maze
    • 22045385
    • Sase A, Khan D, Höger H, Lubec G. Intraperitoneal injection of saline modulates hippocampal brain receptor complex levels but does not impair performance in the Morris Water Maze. Amino Acids 2012, 43(2):783-792. 10.1007/s00726-011-1130-9, 22045385.
    • (2012) Amino Acids , vol.43 , Issue.2 , pp. 783-792
    • Sase, A.1    Khan, D.2    Höger, H.3    Lubec, G.4
  • 50
    • 80053611552 scopus 로고    scopus 로고
    • Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome
    • 21487657
    • Veeraragavan S, Bui N, Perkins JR, Yuva-Paylor LA, Carpenter RL, Paylor R. Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome. Psychopharmacology (Berl) 2011, 217(1):143-151. 10.1007/s00213-011-2276-6, 21487657.
    • (2011) Psychopharmacology (Berl) , vol.217 , Issue.1 , pp. 143-151
    • Veeraragavan, S.1    Bui, N.2    Perkins, J.R.3    Yuva-Paylor, L.A.4    Carpenter, R.L.5    Paylor, R.6
  • 51
    • 84856809219 scopus 로고    scopus 로고
    • Participation of hippocampal cholinergic system in memory persistence for inhibitory avoidance in rats
    • 22197915
    • Parfitt GM, Campos RC, Barbosa AK, Koth AP, Barros DM. Participation of hippocampal cholinergic system in memory persistence for inhibitory avoidance in rats. Neurobiol Learn Mem 2012, 97(2):183-188. 10.1016/j.nlm.2011.12.001, 22197915.
    • (2012) Neurobiol Learn Mem , vol.97 , Issue.2 , pp. 183-188
    • Parfitt, G.M.1    Campos, R.C.2    Barbosa, A.K.3    Koth, A.P.4    Barros, D.M.5
  • 52
    • 0242653760 scopus 로고    scopus 로고
    • Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity
    • 14622908
    • Vaynman S, Ying Z, Gomez-Pinilla F. Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity. Neuroscience 2003, 122(3):647-657. 10.1016/j.neuroscience.2003.08.001, 14622908.
    • (2003) Neuroscience , vol.122 , Issue.3 , pp. 647-657
    • Vaynman, S.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 54
    • 0030956323 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training
    • 20151, 9122258
    • Guzowski JF, McGaugh JL. Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training. Proc Natl Acad Sci U S A 1997, 94(1):2693-2698. 20151, 9122258.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.1 , pp. 2693-2698
    • Guzowski, J.F.1    McGaugh, J.L.2
  • 55
    • 77953609578 scopus 로고    scopus 로고
    • Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats
    • 20457216
    • Feng S, Wang Q, Wang H, Peng Y, Wang L, Lu Y, Shi T, Xiong L. Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats. Neurosci Lett 2010, 478(3):150-155. 10.1016/j.neulet.2010.05.006, 20457216.
    • (2010) Neurosci Lett , vol.478 , Issue.3 , pp. 150-155
    • Feng, S.1    Wang, Q.2    Wang, H.3    Peng, Y.4    Wang, L.5    Lu, Y.6    Shi, T.7    Xiong, L.8
  • 58
    • 46249103251 scopus 로고    scopus 로고
    • Effect of acupuncture given at the HT 7, ST 36, ST 40 and KI 3 acupoints on various parts of the brains of Alzheimer' s disease patients
    • Zhou Y, Jin J. Effect of acupuncture given at the HT 7, ST 36, ST 40 and KI 3 acupoints on various parts of the brains of Alzheimer' s disease patients. Acupunct Electrother Res 2008, 33(1-2):9-17.
    • (2008) Acupunct Electrother Res , vol.33 , Issue.1-2 , pp. 9-17
    • Zhou, Y.1    Jin, J.2
  • 59
    • 57649210670 scopus 로고    scopus 로고
    • Acupuncture protected cerebral multi-infarction rats from memory impairment by regulating the expression of apoptosis related genes Bcl-2 and Bax in hippocampus
    • 18938189
    • Wang T, Liu CZ, Yu JC, Jiang W, Han JX. Acupuncture protected cerebral multi-infarction rats from memory impairment by regulating the expression of apoptosis related genes Bcl-2 and Bax in hippocampus. Physiol Behav 2009, 96(1):155-161. 10.1016/j.physbeh.2008.09.024, 18938189.
    • (2009) Physiol Behav , vol.96 , Issue.1 , pp. 155-161
    • Wang, T.1    Liu, C.Z.2    Yu, J.C.3    Jiang, W.4    Han, J.X.5
  • 60
    • 84899526698 scopus 로고    scopus 로고
    • Effects of acupuncture stimulation at different acupoints on formalin-induced pain in rats
    • 3994298, 24757373
    • Chang KH, Bai SJ, Lee H, Lee BH. Effects of acupuncture stimulation at different acupoints on formalin-induced pain in rats. Korean J Physiol Pharmacol 2014, 18(2):121-127. 10.4196/kjpp.2014.18.2.121, 3994298, 24757373.
    • (2014) Korean J Physiol Pharmacol , vol.18 , Issue.2 , pp. 121-127
    • Chang, K.H.1    Bai, S.J.2    Lee, H.3    Lee, B.H.4


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