Micro-fractional epidermal powder delivery for improved skin vaccination

Journal of Controlled Release

Volumn 192, Issue , 2014, Pages 310-316

  Chen, Xinyuan ^a   Kositratna, Garuna ^a   Zhou, Chang ^a   Manstein, Dieter ^a   Wu, Mei X ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

Author keywords

Laser; Local reactogenicity; Microneedle; Powder delivery; Skin vaccination; Vaccine adjuvant

Indexed keywords

IMMUNE SYSTEM; LASERS; NEEDLES; SKIN; VIRUSES;

HUMORAL IMMUNE RESPONSE; INTRAMUSCULAR VACCINATION; LOCAL REACTOGENICITY; MICRONEEDLES; SKIN VACCINATIONS; TECHNICAL DIFFICULTIES; TOPICAL APPLICATION; VACCINE ADJUVANTS;

VACCINES; LASERS;

BCG VACCINE; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; OVALBUMIN; SULFORHODAMINE B; IMMUNOLOGICAL ADJUVANT; LISSAMINE RHODAMINE B; RHODAMINE; VACCINE; AGATOLIMOD; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; STAINLESS STEEL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG COATING; DRUG DELIVERY SYSTEM; EPIDERMAL POWDER DELIVERY; EPIDERMIS; EXPERIMENTAL PIG; HUMAN; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGENICITY; INJECTION SITE REACTION; INTRADERMAL DRUG ADMINISTRATION; LASER; LOW LEVEL LASER THERAPY; MICRONEEDLE; MOUSE; NONHUMAN; POWDER; PRIORITY JOURNAL; SKIN FUNCTION; SKIN VACCINATION; VACCINATION; VACCINIA VIRUS; ANIMAL; BAGG ALBINO MOUSE; DEVICES; METABOLISM; MICROINJECTION; NEEDLE; PIG; SKIN; CARBON DIOXIDE LASER; DENDRITIC CELL; ERYTHEMA; LANGERHANS CELL; MICRO FRACTIONAL EPIDERMAL POWDER DELIVERY; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPE; SKIN COLOR; SKIN DEFECT; SKIN SURFACE; STRATUM CORNEUM; SWELLING; ULCER; VIRUS LOAD;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, CUTANEOUS; ANIMALS; HUMANS; INJECTIONS, INTRADERMAL; LASERS; MICE; MICE, INBRED BALB C; MICROINJECTIONS; NEEDLES; OVALBUMIN; RHODAMINES; SKIN; SWINE; VACCINATION; VACCINES;

EID: 84907251462     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.08.006     Document Type: Article

References (38)

1. Y.C. Kim, and M.R. Prausnitz Enabling skin vaccination using new delivery technologies Drug Deliv. Transl. Res. 1 2011 7 12
2. D. Chen, Y.F. Maa, and J.R. Haynes Needle-free epidermal powder immunization Expert Rev. Vaccines 1 2002 265 276 (Pubitemid 36559863)
3. G.M. Glenn, M. Rao, G.R. Matyas, and C.R. Alving Skin immunization made possible by cholera toxin Nature 391 1998 851 (Pubitemid 28157653)
4. P. Karande, and S. Mitragotri Transcutaneous immunization: an overview of advantages, disease targets, vaccines, and delivery technologies Annu. Rev. Chem. Biomol. Eng. 1 2010 175 201
5. M.A. Kendall Needle-free vaccine injection Handb. Exp. Pharmacol. 2010 193 219
6. P.M. Jeena, M.K. Chhagan, J. Topley, and H.M. Coovadia Safety of the intradermal Copenhagen 1331 BCG vaccine in neonates in Durban, South Africa Bull. World Health Organ. 79 2001 337 343 (Pubitemid 32303729)
7. J. Lang, D.Q. Hoa, N.V. Gioi, N.C. Vien, C.V. Nguyen, N. Rouyrre, and R. Forrat Immunogenicity and safety of low-dose intradermal rabies vaccination given during an expanded programme on immunization session in Viet Nam: results of a comparative randomized trial Trans. R. Soc. Trop. Med. Hyg. 93 1999 208 213 (Pubitemid 29233864)
8. I. Leroux-Roels, E. Vets, R. Freese, M. Seiberling, F. Weber, C. Salamand, and G. Leroux-Roels Seasonal influenza vaccine delivered by intradermal microinjection: a randomised controlled safety and immunogenicity trial in adults Vaccine 26 2008 6614 6619
9. X. Chen, and M.X. Wu Laser vaccine adjuvant for cutaneous immunization Expert Rev. Vaccines 10 2011 1397 1403
10. X. Chen, J. Wang, D. Shah, and M.X. Wu An update on the use of laser technology in skin vaccination Expert Rev. Vaccines 12 2013 1313 1323
11. J. Gupta, H.S. Gill, S.N. Andrews, and M.R. Prausnitz Kinetics of skin resealing after insertion of microneedles in human subjects J. Control. Release 154 2011 148 155
12. H. Kalluri, and A.K. Banga Formation and closure of microchannels in skin following microporation Pharm. Res. 28 2011 82 94
13. X. Chen, D. Shah, G. Kositratna, D. Manstein, R.R. Anderson, and M.X. Wu Facilitation of transcutaneous drug delivery and vaccine immunization by a safe laser technology J. Control. Release 159 2012 43 51
14. Y.C. Kim, J.H. Park, and M.R. Prausnitz Microneedles for drug and vaccine delivery Adv. Drug Deliv. Rev. 64 2012 1547 1568
15. X. Chen, P. Kim, B. Farinelli, A. Doukas, S.H. Yun, J.A. Gelfand, R.R. Anderson, and M.X. Wu A novel laser vaccine adjuvant increases the motility of antigen presenting cells PLoS One 5 2010 e13776
16. L. Liu, Q. Zhong, T. Tian, K. Dubin, S.K. Athale, and T.S. Kupper Epidermal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell-mediated immunity Nat. Med. 16 2010 224 227
17. W.R. Lee, S.C. Shen, M.H. Pai, H.H. Yang, C.Y. Yuan, and J.Y. Fang Fractional laser as a tool to enhance the skin permeation of 5-aminolevulinic acid with minimal skin disruption: a comparison with conventional erbium:YAG laser J. Control. Release 145 2010 124 133
18. M. Hessenberger, R. Weiss, E.E. Weinberger, C. Boehler, J. Thalhamer, and S. Scheiblhofer Transcutaneous delivery of CpG-adjuvanted allergen via laser-generated micropores Vaccine 31 2013 3427 3434
19. Z. Ding, F.J. Verbaan, M. Bivas-Benita, L. Bungener, A. Huckriede, D.J. van den Berg, G. Kersten, and J.A. Bouwstra Microneedle arrays for the transcutaneous immunization of diphtheria and influenza in BALB/c mice J. Control. Release 136 2009 71 78
20. W. Martanto, J.S. Moore, T. Couse, and M.R. Prausnitz Mechanism of fluid infusion during microneedle insertion and retraction J. Control. Release 112 2006 357 361 (Pubitemid 43737149)
21. R.H. Behrens, J.P. Cramer, T. Jelinek, H. Shaw, F. von Sonnenburg, D. Wilbraham, T. Weinke, D.J. Bell, E. Asturias, H.L. Pauwells, R. Maxwell, M. Paredes-Paredes, G.M. Glenn, S. Dewasthaly, D.M. Stablein, Z.D. Jiang, and H.L. Dupont Efficacy and safety of a patch vaccine containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala Lancet Infect. Dis. 14 2013 197 204
22. D.M. Frerichs, L.R. Ellingsworth, S.A. Frech, D.C. Flyer, C.P. Villar, J. Yu, and G.M. Glenn Controlled, single-step, stratum corneum disruption as a pretreatment for immunization via a patch Vaccine 26 2008 2782 2787
23. F. Marquet, M. Bonneau, F. Pascale, C. Urien, C. Kang, I. Schwartz-Cornil, and N. Bertho Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model PLoS One 6 2011 e16320
24. P.E. Laurent, S. Bonnet, P. Alchas, P. Regolini, J.A. Mikszta, R. Pettis, and N.G. Harvey Evaluation of the clinical performance of a new intradermal vaccine administration technique and associated delivery system Vaccine 25 2007 8833 8842 (Pubitemid 350192056)
25. G. Trinchieri, and A. Sher Cooperation of Toll-like receptor signals in innate immune defence Nat. Rev. Immunol. 7 2007 179 190
26. S.J. Draper, and J.L. Heeney Viruses as vaccine vectors for infectious diseases and cancer Nat. Rev. Microbiol. 8 2010 62 73
27. F.E. Pearson, C.L. McNeilly, M.L. Crichton, C.A. Primiero, S.R. Yukiko, G.J. Fernando, X. Chen, S.C. Gilbert, A.V. Hill, and M.A. Kendall Dry-coated live viral vector vaccines delivered by nanopatch microprojections retain long-term thermostability and induce transgene-specific T cell responses in mice PLoS One 8 2013 e67888
28. M. Haedersdal, F.H. Sakamoto, W.A. Farinelli, A.G. Doukas, J. Tam, and R.R. Anderson Fractional CO(2) laser-assisted drug delivery Lasers Surg. Med. 42 2010 113 122
29. W.R. Lee, T.L. Pan, P.W. Wang, R.Z. Zhuo, C.M. Huang, and J.Y. Fang Erbium:YAG laser enhances transdermal peptide delivery and skin vaccination J. Control. Release 128 2008 200 208
30. S.N. Andrews, E. Jeong, and M.R. Prausnitz Transdermal delivery of molecules is limited by full epidermis, not just stratum corneum Pharm. Res. 30 2013 1099 1109
31. E.E. Kis, G. Winter, and J. Myschik Devices for intradermal vaccination Vaccine 30 2012 523 538
32. D. McAdams, D. Chen, and D. Kristensen Spray drying and vaccine stabilization Expert Rev. Vaccines 11 2012 1211 1219
33. R. Alcock, M.G. Cottingham, C.S. Rollier, J. Furze, S.D. De Costa, M. Hanlon, A.J. Spencer, J.D. Honeycutt, D.H. Wyllie, S.C. Gilbert, M. Bregu, and A.V. Hill Long-term thermostabilization of live poxviral and adenoviral vaccine vectors at supraphysiological temperatures in carbohydrate glass Sci. Transl. Med. 2 2010 19ra12
34. T. Sou, E.N. Meeusen, M. de Veer, D.A. Morton, L.M. Kaminskas, and M.P. McIntosh New developments in dry powder pulmonary vaccine delivery Trends Biotechnol. 29 2011 191 198
35. L. Craig, D. Elliman, R. Heathcock, D. Turbitt, B. Walsh, and N. Crowcroft Pragmatic management of programmatic vaccination errors - lessons learnt from incidents in London Vaccine 29 2010 65 69
36. S.P. Sullivan, D.G. Koutsonanos, M.M. Del Pilar, J.W. Lee, V. Zarnitsyn, S.O. Choi, N. Murthy, R.W. Compans, I. Skountzou, and M.R. Prausnitz Dissolving polymer microneedle patches for influenza vaccination Nat. Med. 16 2010 915 920
37. J.K. Hickling, K.R. Jones, M. Friede, D. Zehrung, D. Chen, and D. Kristensen Intradermal delivery of vaccines: potential benefits and current challenges Bull. World Health Organ. 89 2011 221 226
38. D. Chen, and D. Kristensen Opportunities and challenges of developing thermostable vaccines Expert Rev. Vaccines 8 2009 547 557