C-terminal domain (CTD) small phosphatase-like 2 modulates the canonical bone morphogenetic protein (BMP) signaling and mesenchymal differentiation via smad dephosphorylation

Journal of Biological Chemistry

Volumn 289, Issue 38, 2014, Pages 26441-26450

  Zhao, Yulan ^a   Xiao, Mu ^a   Sun, Baoguo ^b   Zhang, Zhengmao ^b   Shen, Tao ^b,c   Duan, Xueyan ^b   Yu, Paul Borchyung ^d   Feng, Xin Hua ^a,b   Lin, Xia ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASES;

BONE MORPHOGENETIC PROTEINS; C-TERMINAL DOMAINS; CELLULAR PROCESS; DEPHOSPHORYLATES; DEPHOSPHORYLATIONS; ECTOPIC EXPRESSIONS; PHYSIOLOGICAL FUNCTIONS;

SIGNALING;

BONE MORPHOGENETIC PROTEIN 2; PHOSPHATASE; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; SMALL C TERMINAL DOMAIN PHOSPHATASE 4; UNCLASSIFIED DRUG; BONE MORPHOGENETIC PROTEIN; CTDSPL2 PROTEIN, MOUSE; IDB1 PROTEIN, MOUSE; INHIBITOR OF DIFFERENTIATION 1; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN BINDING; RNA POLYMERASE II; SMAD1 PROTEIN, MOUSE;

ARTICLE; BONE DEVELOPMENT; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION REGULATION; GENE LOCATION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MULTIPOTENT STEM CELL; PROTEIN DEPHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; ENZYME ACTIVE SITE; GENE EXPRESSION; GENETICS; MESODERM; METABOLISM; MOUSE; OSTEOBLAST; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN MOTIF; PROTEIN PROCESSING;

AMINO ACID MOTIFS; ANIMALS; BONE MORPHOGENETIC PROTEINS; CATALYTIC DOMAIN; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; MESODERM; MICE; OSTEOBLASTS; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA POLYMERASE II; SIGNAL TRANSDUCTION; SMAD1 PROTEIN;

EID: 84907210862     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.568964     Document Type: Article

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