Guava leaf extract inhibits quorum-sensing and chromobacterium violaceum induced lysis of human hepatoma cells: Whole transcriptome analysis reveals differential gene expression

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Ghosh, Runu ^a   Tiwary, Bipransh Kumar ^a   Kumar, Anoop ^a   Chakraborty, Ranadhir ^a  

^a UNIVERSITY OF NORTH BENGAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GUAVA EXTRACT; TRANSCRIPTOME; INDOLE DERIVATIVE; PLANT EXTRACT; VIOLACEIN; VIRULENCE FACTOR; WATER;

ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CHROMOBACTERIUM VIOLACEUM; CONTROLLED STUDY; CYTOLYSIS; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE TARGETING; HEPG2 CELL LINE; HUMAN; HUMAN CELL; MICROBIAL ATTENUATION; NONHUMAN; PHENOTYPE; PROTEIN ANALYSIS; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; BACTERIAL GENOME; CELL DEATH; CHEMISTRY; CHROMOBACTERIUM; CYTOLOGY; DRUG EFFECTS; GENE REGULATORY NETWORK; GENETICS; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; PLANT LEAF; PSIDIUM; TIME;

CHROMOBACTERIUM VIOLACEUM; PSIDIUM;

CARCINOMA, HEPATOCELLULAR; CELL DEATH; CHROMOBACTERIUM; DOWN-REGULATION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENOME, BACTERIAL; HEP G2 CELLS; HUMANS; INDOLES; LIVER NEOPLASMS; PHENOTYPE; PLANT EXTRACTS; PLANT LEAVES; PSIDIUM; QUORUM SENSING; TIME FACTORS; VIRULENCE FACTORS; WATER;

EID: 84907199422     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107703     Document Type: Article

References (71)

1. Rasmussen TB, Givskov M (2006) Quorum-sensing inhibitors as anti-pathogenic drugs. Intl J Med Microbiol 296: 149-161.
2. Clatworthy AE, Pierson E, Hung DT (2007) Targeting virulence: a new paradigm for antimicrobial therapy. Nat Chem Biol 3: 541-548.
3. Kalia VC, Purohit HJ (2011) Quenching the quorum sensing system: potential antibacterial drug targets. Crit Rev Microbiol 37: 121-140.
4. Williams P (2007) Quorum sensing, communication and cross-kingdom signalling in the bacterial world. Microbiology 153: 3923-3938.
5. Sarkar S, Chakraborty R (2008) Quorum sensing in metal tolerance of Acinetobacter junii BB1A is associated with biofilm production. FEMS Microbiol. Lett 282: 160-165.
6. Dandekar AA, Chugani S, Greenberg EP (2012) Bacterial quorum sensing and metabolic incentives to cooperate. Science 338: 264-266.
7. Waters CM, Bassler BL (2005) Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell Dev Biol 21: 319-346.
8. Schuster M, Sexton DJ, Diggle SP, Greenberg EP (2013) Acyl-homoserine lactone quorum sensing: From evolution to application. Annu Rev Microbiol 67: 43-63.
9. Rutherford ST, Bassler BL (2012) Bacterial quorum sensing: Its role in virulence and possibilities for its control. Cold Spring Harb Perspect Med 2: a01242.
10. Koburger JA, May SO (1982) Isolation of Chromobacterium spp. from foods, soil, and water. Appl Environ Microbiol 44: 1463-1465.
11. Orsetti AG, Markiewicz P, Epstein MG, Conceiçao OJG, D'Ippolito G, et al. (2013) Liver abscesses by Chromobacterium violaceum: a case report of a rare disease. OA Case Reports 28: 19-23.
12. Teoh AYB, Hui M, Ngo KY, Wong J, Lee KF, et al. (2006) Fatal septicaemia from Chromobacterium violaceum: Case reports and review of the literature. Hong Kong Med J 12: 228-231.
13. Karthik R, Pancharatnam P, Balaji V (2012) Case Report Fatal Chromobacterium violaceum septicemia in a South Indian adult. J Infect Dev Ctries 6: 751-755.
14. Fantinatti-Garboggini F, Almeida R, Portillo VA, Barbosa TA, Trevilato PB, et al. (2004) Drug resistance in Chromobacterium violaceum. Genet Mol Res 3: 134-147.
15. Swem LR, Swem DL, O'Loughlin CT, Gatmaitan R, Zhao B, et al. (2009) A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity. Mol Cell 35: 143-153.
16. Vasconcelos ATR, Almeida de DF, Hungria M, Guimarães CT, Antonio RV, et al. (2003) The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability. Proc Natl Acad Sci USA 100: 11660-11665.
17. Martinelli D, Grossmann G, Sequin U, Brandl H, Bachofen R (2004) Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum. BMC Microbiol 4:25.
18. Kalia VC (2013) Quorum sensing inhibitors: An overview. Biotechnol Adv 31: 224-245.
19. Koh KH, Tham FY (2011) Screening of traditional Chinese medicinal plants for quorum-sensing inhibitors activity. J Microbiol Immunol Infect 44: 144-148.
20. Vasavi HS, Arun AB, Rekha PD (2013) Inhibition of quorum sensing in Chromobacterium violaceum by Syzygium cumini L. and Pimenta dioica L. Asian Pac J Trop Biomed 3: 954-959.
21. Priya K, Yin W-F, Chan K-GF (2013) Anti-Quorum Sensing Activity of the Traditional Chinese Herb, Phyllanthus amarus. Sensors 13: 14558-14569.
22. Gilbert B, Alves LF (2003) Synergy in Plant Medicines. Curr Med Chem 10: 13-
23. Rasoanaivo P, Wright CW, Willcox ML, Gilbert B (2011) Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. Malar J (Suppl 1): S4.
24. Ginsburg H, Deharo E (2011) A call for using natural compounds in the development of new antimalarial treatments-an introduction. Malar J (Suppl 1): S1.
25. Wagner H, Ulrich-Merzenich G (2009) Synergy research: approaching a new generation of phytopharmaceuticals. Phytomedicine 16: 97-110.
26. Gutierrez RM, Mitchell S, Solis RV (2008) Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol 117: 1-27.
27. Barbalho SM, Farinazzi-Machado FMV, de Alvares GR, Brun-nati ACS, Otoboni AM, et al. (2012) Psidium Guajava (Guava): A plant of mul-tipurpose medicinal applications. Med Aromat Plants 1: 104-109.
28. Metwally AM, Omar AA, Harraz FM, El Sohafy SM (2010) Phytochemical investigation and antimicrobial activity of Psidium guajava L leaves. Pharmacogn Mag 6: 212-218.
29. Birdi T, Daswani P, Brijesh S, Tetali P, Natu A, et al. (2010) Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea. BMC Complement Altern Med 10:33.
30. Chen HY, Yen GC (2007) Antioxidant activity and free radical-scavenging capacity of extracts from guava (Psidium guajava L) leaves. Food Chem 101: 686-694.
31. Matsuo T, Hanamure N, Shimoi K, Nakamura Y, Tomita I (1994) Identification of (+)-gallocatechin as a bio-antimutagenic compound in Psidium guava leaves. Phytochemistry 36: 1027-1029.
32. Ryu NH, Park KR, Kim SM, Yun HM, Nam D, et al. (2012) A Hexane Fraction of Guava Leaves (Psidium guajava L.) Induces Anticancer Activity by Suppressing AKT/Mammalian Target of Rapamycin/Ribosomal p70 S6 Kinase in Human Prostate Cancer Cells. J Med Food 15: 231-241.
33. Deguchi Y, Miyazaki K (2010) Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract. Nutr Metab (Lond) 7: 9.
34. Prabu GR, Gnanamani A, Sadulla S (2006) Guaijaverin-a plant flavonoid as potential antiplaque agent against Streptococcus mutans. J Appl Microbiol 101: 487-495.
35. Quave CL, Plano LRW, Pantuso T, Bennett BC (2008) Effects of extracts from Italian medicinal plants on planktonic growth, biofilm formation and adherence of methicillin-resistant Staphylococcus aureus. J Ethnopharmacol 118: 418-428.
36. Al-Hussaini R, Mahasneh AM (2009) Microbial growth and quorum sensing antagonist activities of herbal plants extracts. Molecules 14: 3425-3435.
37. Tremblay J, Richardson AP, Lepine F, Deziel E (2007) Self-produced extracellular stimuli modulate the Pseudomonas aeruginosa swarming motility behaviour. Environ Microbiol 9: 2622-2630.
38. Choo JH, Rukayadi Y, Hwang J-K (2006). Inhibition of bacterial quorum sensing by vanilla extract. Lett Appl Microbiol 42: 637-641.
39. Miller JH (1972) Determination of viable cell counts: bacterial growth curves. Experiments in Molecular Genetics. Cold Spring Harbor Press: New York, pp 31-36.
40. McLean RJ, Pierson LS III, Fuqua C (2004) A simple screening protocol for the identification of quorum signal antagonists. J Microbiol Methods 58: 351-360.
41. Defoirdt T, Brackman G, Coenye T (2013) Quorum sensing inhibitors: how strong is the evidence? Trends Microbiol 21: 619-624.
42. Adonizio AL, Downum K, Bennett BC, Mathee K (2006) Anti-quorum sensing activity of medicinal plants in southern Florida. J Ethnopharmacol 105: 427-435.
43. Koh KH, Tham FY (2011) Screening of traditional Chinese medicinal plants for quorum-sensing inhibitors activity. J Microbiol Immunol Infect 44: 144-148.
44. May CO, Tufenkji N (2011) The swarming motility of P. aeruginosa is blocked by cranberry proanthocyanidins and other tannin containing materials. Appl Environ Microbiol 77: 3061-3067.
45. Wagner VE, Bushnell D, Passador L, Brooks AI, Iglewski BH (2003) Microarray analysis of Pseudomonas aeruginosa quorum-sensing regulons: effects of growth phase and environment. J Bacteriol 185: 2080-2095.
46. DeLisa MP, Wu CF, Wang L, Valdes JJ, Bentley WE (2001) DNA microarraybased identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. J Bacteriol 183: 5239-5247.
47. Yang CH, Li YH (2011) Chromobacterium violaceum infection: a clinical review of an important but neglected infection. J Chin Med Assoc 74: 435-441.
48. Schuster M, Lostroh CP, Ogi T, Greenberg EP (2003) Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol 185: 2066-2079.
49. Passador LJ, Cook M, Gambello MJ, Rust L, Iglewski BH (1993) Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication. Science 260: 1127-1130.
50. Baca-DeLancey RR, South MM, Ding X, Rather PN (1999) Escherichia coli genes regulated by cell-to-cell signaling. Proc Natl Acad Sci USA 96: 4610-4614.
51. Hentzer M, Wu H, Andersen JB, Riedel K, Rasmussen TB, et al. (2003) Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J 22: 3803-3815.
52. Kessler E (1995) Beta-lytic endopeptidases. Methods Enzymol 248: 740-756.
53. Preston M, Seed P, Toder D, Iglewski B, Ohman D, et al. (1997) Contribution of proteases and LasR to the virulence of Pseudomonas aeruginosa during corneal infections. Infect Immun 65: 3086-3090.
54. Duran N, Menck CF (2001) Chromobacterium violaceum: a review of pharmacological and industiral perspectives. Crit Rev Microbiol 27: 201-222.
55. Chernin LS, Winson MK, Thompson JM, Haran S, Bycroft BW, et al. (1998) Chitinolytic activity in Chromobacterium violaceum: substrate analysis and regulation by quorum sensing. J Bacteriol 180: 4435-4441.
56. Schaefer AL, Val DL, Hanzelka BL, Cronan JE, Greenberg EP (1996) Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein. Proc Natl Acad Sci USA 93: 9505-9509.
57. Stauff DL, Bassler BL (2011) Quorum Sensing in Chromobacterium violaceum: DNA Recognition and Gene Regulation by the CviR Receptor. J Bact 193: 3871-3878.
58. Brito CFAD, Carvalho CMB, Santos FR, Gazzinelli RT, Oliveira SC, et al. (2004) Chromobacterium violaceum genome: molecular mechanisms associated with pathogenicity. Genet Mol Res 3: 148-161.
59. Bieber D, Ramer SW, Wu CY, Murray WJ, Tobe T, et al. (1998) Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli. Science 280: 2114-2118.
60. Kennan RM, Dhungyel OP, Whittington RJ, Egerton JR, Rood JI (2001) The type IV fimbrial subunit gene (fimA) of Dichelobacter nodosus is essential for virulence, protease secretion, and natural competence. J Bacteriol 183: 4451-4458.
61. Castro-Gomes T, Cardoso MS, DaRocha WD, Laibida LA, Nascimento AM, et al. (2014) Identification of secreted virulence factors of Chromobacterium violaceum. J Microbiol 52: 350-353.
62. Miki T, Iguchi M, Akiba K, Hosono M, Sobue T, et al. (2010) Chromobacterium pathogenicity island 1 type III secretion system is a major virulence determinant for Chromobacterium violaceum-induced cell death in hepatocytes. Mol Microbiol 77: 855-872.
63. Atkinson S, Throup JP, Stewart GSAB, Williams P (1999) A hierarchical quorum-sensing system in Yersinia pseudotuberculosis is involved in the regulation of motility and clumping. Mol Microbiol 33: 1267-1277.
64. Yang Q, Defoirdt T (2014) Quorum sensing positively regulates flagellar motility in pathogenic Vibrio harveyi. Env Microbiol doi:10.1111/1462-2920.12420 (in Press).
65. Recouvreux DO, Carminatti CA, Pitlovanciv AK, Rambo CR, Porto LM, et al. (2008) Cellulose biosynthesis by the beta-proteobacterium, Chromobacterium violaceum. Curr Microbiol 57: 469-476.
66. Wood TK (2009) Insights on Escherichia coli biofilm formation and inhibition from whole-transcriptome profiling. Environ Microbiol 11: 1-15.
67. Lee J-HJ, Kim Y-GY, Cho MHM, Wood TKT, Lee JJ (2011) Transcriptomic analysis for genetic mechanisms of the factors related to biofilm formation in Escherichia coli O157: H7. Curr Microbiol 62: 1321-1330.
68. Liu Z, Wang W, Zhu Y, Gong Q, Yu W, et al. (2013) Antibiotics at subinhibitory concentrations improve the quorum sensing behavior of Chromobacterium violaceum. FEMS Microbiol Lett 341: 37-44.
69. Gu X, Xie Z, Wang Q, Liiu G, Qu Y, et al. (2009) Transcriptome profiling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet. Febs J 276: 1450-1458.
70. Fathilah AR, Rahim ZHA (2003) The anti-adherence effect of Piper betle and Psidium guajava extracts on the adhesion of early settlers in dental plaque to saliva-coated glass surfaces. J Oral Sci 45: 201-206.
71. Defoirdt T, Boon N, Bossier P (2010) Can Bacteria Evolve Resistance to Quorum Sensing Disruption, PLoS Pathog 6: e1000989.