Phytochemical investigation and antimicrobial activity of Psidium guajava L. leaves

Pharmacognosy Magazine

Volumn 6, Issue 23, 2010, Pages 212-218

  Metwally, A M ^a   Omar, A A ^a   Harraz, F M ^a   El Sohafy, S M ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Antimicrobial activity; guava leaves; Psidium guajava L.; quercetin; quercetin glycosides; quercetin 3 O D arabinopyranoside

Indexed keywords

FLAVONOID; GUAVA EXTRACT; QUERCETIN; QUERCETIN 3 O ALPHA LEVO ARABINOFURANOSIDE; QUERCETIN 3 O BETA DEXTRO ARABINOPYRANOSIDE; QUERCETIN 3 O BETA DEXTRO GALACTOSIDE; QUERCETIN 3 O BETA DEXTRO GLUCOSIDE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG SCREENING; FRACTIONATION; GUAVA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; PLANT LEAF;

EID: 78049373183     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: 10.4103/0973-1296.66939     Document Type: Article

References (37)

1. Karawya MS, Abdel Wahab SM, Hifnawy MS, Azzam SM, El Gohary HM. Essential oil of egyptian guajava leaves. Egypt J Biomed Sci 1999;40:209-16.
2. Abdelrahim SI, Almagboul AZ, Omer ME, Elegami A. Antimicrobial activity of Psidium guajava L. Fitoterapia 2002;73:713-5.
3. Begum S, Hassan S, Ali S, Siddiqui B. Chemical constituents from the leaves of Psidium guajava. Nat Prod Res 2004;18:135-40.
4. Lozoya X, Meckes M, Abou-Zaid M, Tortoriello J, Nozzolillo C, Arnason JT. Calcium-antagonist effect of quercetin and its relation with the spasmolytic properties of Psidium guajava L. Arch Med Res 1994;25:11-5.
5. Ishihara T, Han R. Manufacture of guava leaf extracts. Japanese Kokai Tokkyo Koho Patency number JP 10202002, Kind A2, Date 19980804, Application number JP 1997-46858, Date 1997.01.23; 4 pp. (Japan).
6. Sunagawa M, Shimada S, Zhang Z, Oonishi A, Nakamura M, Kosugi T. Plasma Insulin concentration was increased by long-term ingestion of guava juice in spontaneous non-insulin-dependant diabetes mellitus (NIDDM) rats. J Health Sci 2004;50:674-8.
7. Tanaka T, Ishida N, Ishimatsu M, Nonaka G, Nishioka I. Six new complex tannins, guajavins, psidins and psiguavin from the bark of Psidium guajava L. Chem Pharm Bull (Tokyo) 1992;40:2092-8.
8. Tangpu TV, Yadav AK. Anticestodal efficacy of Psidium guajava against experimental Hymenolepis diminuta infection in rats. Indian J Pharmacol 2006;38:29-32.
9. Ojewole JA. Anti-Inflammatory and analgesic effects of Psidium guajava Linn. (Myrtaceae) leaf aqueous extracts in rats and mice. Methods Find Exp Clin Pharmacol 2006;28:441-6.
10. Nair R, Chanda S. In-vitro antimicrobial activity of Psidium guajava L leaf extracts against clinically important pathogenic microbial strains. Braz J Microbiol 2007;38:452-8.
11. Roy K, Kamath V, Asad M. Hepatoprotective activity of Psidium guajava L leaf extract. Indian J Exp Biol 2006;44:305-11.
12. Hui-Yin Chen, Gow-Chin Yen. Antioxidant activity and free radical-scavenging capacity of extracts from guava (Psidium guajava L.) leaves. Food Chem 2007;101:686-94.
13. Zhang W, Chen B, Wang C, Zhu Q, Mo Z. Mechanism of quercetin as antidiarrheal agent. Di Yi Jun Yi Da Xue Xue Bao 2003;23:1029-31.
14. Nakamura Y, Ishimitsu S, Tonogai Y. Effects of quercetin and rutin on serum and hepatic lipid concentrations, fecal steroid excretion and serum antioxidant properties. J Health Sci 2000;46:229-40.
15. Havsteen B. Flavonoids, A class of natural products of high pharmacological potency. Biochem Pharmacol 1983;32:1141-8.
16. Middleton E, Drzewieki G. Flavonoid inhibition of human basophil histamine release stimulated by various agents. Biochem Pharmacol 1984;33:3333-8.
17. Middleton E, Drzewieki G. Naturalty occurring flavonoids and human basophil histamine release. Int Arch Allergy Appl Immunol 1985;77:155-7.
18. Amella M, Bronner C, Briancon F, Haag M, Anton R, Landry Y. Inhibition of mast cell histamine release by flavonoids and bioflavonoids. Planta Med 1985;51:16-20.
19. Pearce F, Befus AD, Bienenstock J. Mucosal mast cells: III Etfect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells. J Allergy Clin Immunol 1984;73:819-23.
20. Busse WW, Kopp DE, Middleton E. Flavonoid modulation of human neutrophil function. J Allergy Clin Immunol 1984;73:801-9.
21. Yoshimoto T, Furukawa M, Yamamoto S, Horie T, Watanabe-Kohno S. Flavonoids Potent inhibitors of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun 1983;116:612-8.
22. Murray MT, Pizzorno JE. Flavonoids-Quercetin, citrus favonoids, and HERs (hydroxylethylrutosides). In: Pizzorno JE, Murray ME, editors. Text book of Natural Medicine. 2 nd ed. London: Harcourt Brace and company Ltd; 1999. p. 745-50.
23. Mucsi I, Pragai BM. Inhibition of virus multiplication and alteration of cyclic AMP level in cell cultures by flavonoids. Experientia 1985;41:930-1.
24. Kaul T, Middleton E, Ogra P. Antiviral effects of flavonoids on human viruses. J Med Virol 1985;15:71-9.
25. Farkas L, Gabor M, kallay F, Wagner HI. Flavonoids and Bioflavonoids. New York: Elsevier; 1982. p. 443-50.
26. Guttner J, Veckenstedt A, Heinecke H, Pusztai R. Effect of quercetin on the course of mengo virus infection in immunodeficient and normal mice: A histological study. Acta Virol 1982;26:148-55.
27. Kaneuchi M, Sasaki M, Tanaka Y, Sakuragi N, Fujimoto S, Dahiya R. Quercetin regulates growth of Ishikawa cells through the suppression of EGF and cyclin D1. Int J Oncol 2003;22:159-64.
28. Chaundry PS, Cabrera J, Juliana HR, Varma SD. Inhibition of human lens aldose reductase by flavonoids, sulindac and indomethacin. Biochem Pharmacol 1983;32:1995-8.
29. Abdel Wahab SM, Hifawy MS, El Gohary HM, Isak M. Study of carbohydrates, lipids, protein, flavonoids, vitamin C and biological activity of Psidium guajava L growing in Egypt. Egypt J Biomed Sci 2004;16:35-52.
30. El Khadem H, Mohamed YS. Constituents of the leaves of Psidium guajava L: Part II: Quercetin, avicularin, and guajaverin. J Chem Soc 1958;32:3320-3.
31. Arima H, Danno G. Isolation of antimicrobial compounds from guava (Psidium guajava L.) and their structural elucidation. Biosci Biotechnol Biochem 2002;66:1727-30.
32. Seshadri T, Vasishta K. Polyphenols of the leaves of Psidium guava; quercetin, guaijaverin, leucocyanidin, amritoside. Phytochemistry 1965;4:989-92.
33. Kandil FE, El-Sayed NH, Micheal HN, Ishak MS, Mabry TJ. Flavonoids from Psidium guajava. Asian J Chem 1997;9:871-2.
34. Jian FR, Kar A. The antibacterial activity of some essensial oils and their combinations. Planta Med 1971;20:118-22.
35. Harbone JB, Mabry TJ. The Flavonoids: Advances in research. London: Chapman and Hall; 1982.
36. Agrawal PK. Carbon-13 NMR of flavonoids. Amsterdam: Elsevier; 1989.
37. Markhan KR, Terani B, Stanley R, Geiger H, Mabry TJ. Carbon-13 NMR studies of flavonoid glycosides and their acylated derivatives. Tetrahedron 1978;34:1389-97.