Effects of lubiprostone on pacemaker activity of interstitial cells of cajal from the mouse colon

Korean Journal of Physiology and Pharmacology

Volumn 18, Issue 4, 2014, Pages 341-346

  Jun, Jae Yeoul ^a   Jiao, Han Yi ^a   Kim, Dong Hyun ^a   Ki, Jung Suk ^a   Ryu, Kwon Ho ^a   Choi, Seok ^a  

^a Chosun University College of Medicine   (South Korea)

Author keywords

Acemaker potentials; Colon; Nterstitial cells of Cajal; Ubiprostone

Indexed keywords

1 ACETYL 2 (8 CHLORO 10,11 DIHYDRODIBENZ[B,F][1,4]OXAZEPINE 10 CARBONYL)HYDRAZINE; 6 METHOXYPYRIDINE 2 BORONIC ACID N PHENYLDIETHANOLAMINE ESTER; APAMIN; GLIBENCLAMIDE; GW 627368; LUBIPROSTONE; PF 04418948; PINACIDIL; PROSTAGLANDIN E RECEPTOR 1; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 3; PROSTAGLANDIN E RECEPTOR 4; TETRYLAMMONIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVITY; COLON; DRUG EFFECT; DRUG MECHANISM; IMMUNOFLUORESCENCE TEST; INTERSTITIAL CELL OF CAJAL; MOUSE; NONHUMAN; PATCH CLAMP TECHNIQUE;

EID: 84907197130     PISSN: 12264512     EISSN: 20933827     Source Type: Journal    
DOI: 10.4196/kjpp.2014.18.4.341     Document Type: Article

References (32)

1. McKeage K, Plosker GL, Siddiqui MA. Lubiprostone. Drugs. 2006;66:873-879. [PubMed]
2. Lacy BE, Chey WD. Lubiprostone: chronic constipation and irritable bowel syndrome with constipation. Expert Opin Pharmacother. 2009;10:143-152. [PubMed]
3. Carter NJ, Scott LJ. Lubiprostone: in constipation-predominant irritable bowel syndrome. Drugs. 2009;69:1229-1237. [PubMed]
4. Schey R, Rao SS. Lubiprostone for the treatment of adults with constipation and irritable bowel syndrome. Dig Dis Sci. 2011;56:1619-1625. [PubMed]
5. Crowell MD, Harris LA, DiBaise JK, Olden KW. Activation of type-2 chloride channels: a novel therapeutic target for the treatment of chronic constipation. Curr Opin Investig Drugs. 2007;8:66-70. [PubMed]
6. Bijvelds MJ, Bot AG, Escher JC, De Jonge HR. Activation of intestinal Cl secretion by lubiprostone requires the cystic fibrosis transmembrane conductance regulator. Gastroenterology. 2009;137:976-985. [PubMed]
7. Fei G, Wang YZ, Liu S, Hu HZ, Wang GD, Qu MH, Wang XY, Xia Y, Sun X, Bohn LM, Cooke HJ, Wood JD. Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon. Am J Physiol Gastrointest Liver Physiol. 2009;296:G823-G832. [PMC free article] [PubMed]
8. Norimatsu Y, Moran AR, MacDonald KD. Lubiprostone activates CFTR, but not ClC-2, via the prostaglandin receptor (EP(4)) Biochem Biophys Res Commun. 2012;426:374-379. [PMC free article] [PubMed]
9. Lembo AJ, Schneier HA, Shiff SJ, Kurtz CB, MacDougall JE, Jia XD, Shao JZ, Lavins BJ, Currie MG, Fitch DA, Jeglinski BI, Eng P, Fox SM, Johnston JM. Two randomized trials of linaclotide for chronic constipation. N Engl J Med. 2011;365:527-536. [PubMed]
10. Ao M, Venkatasubramanian J, Boonkaewwan C, Ganesan N, Syed A, Benya RV, Rao MC. Lubiprostone activates Cl secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84. Dig Dis Sci. 2011;56:339-351. [PubMed]
11. Lacy BE, Levy LC. Lubiprostone: a chloride channel activator. J Clin Gastroenterol. 2007;41:345-351. [PubMed]
12. Cuppoletti J, Malinowska DH, Chakrabarti J, Ueno R. Effects of lubiprostone on human uterine smooth muscle cells. Prostaglandins Other Lipid Mediat. 2008;86:56-60. [PubMed]
13. Camilleri M, Bharucha AE, Ueno R, Burton D, Thomforde GM, Baxter K, McKinzie S, Zinsmeister AR. Effect of a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory, and motor functions in healthy volunteers. Am J Physiol Gastrointest Liver Physiol. 2006;290:G942-G947. [PubMed]
14. Bassil AK, Borman RA, Jarvie EM, McArthur-Wilson RJ, Thangiah R, Sung EZ, Lee K, Sanger GJ. Activation of prostaglandin EP receptors by lubiprostone in rat and human stomach and colon. Br J Pharmacol. 2008;154:126-135. [PMC free article] [PubMed]
15. Chan WW, Mashimo H. Lubiprostone Increases Small Intestinal Smooth Muscle Contractions Through a Prostaglandin E Receptor 1 (EP1)- mediated Pathway. J Neurogastroenterol Motil. 2013;19:312-318. [PMC free article] [PubMed]
16. Thomsen L, Robinson TL, Lee JC, Farraway LA, Hughes MJ, Andrews DW, Huizinga JD. Interstitial cells of Cajal generate a rhythmic pacemaker current. Nat Med. 1998;4:848-851. [PubMed]
17. Sanders KM, Koh SD, Ward SM. Interstitial cells of cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol. 2006;68:307-343. [PubMed]
18. Kim BJ, Kwon YK, Kim E, So I. Effects of histamine on cultured interstitial cells of cajal in murine small intestine. Korean J Physiol Pharmacol. 2013;17:149-156. [PMC free article] [PubMed]
19. Rumessen JJ, Thuneberg L. Pacemaker cells in the gastrointestinal tract: interstitial cells of Cajal. Scand J Gastroenterol Suppl. 1996;216:82-94. [PubMed]
20. Komuro T. Structure and organization of interstitial cells of Cajal in the gastrointestinal tract. J Physiol. 2006;576:653-658. [PMC free article] [PubMed]
21. Jain D, Moussa K, Tandon M, Culpepper-Morgan J, Proctor DD. Role of interstitial cells of Cajal in motility disorders of the bowel. Am J Gastroenterol. 2003;98:618-624. [PubMed]
22. Farrugia G. Interstitial cells of Cajal in health and disease. Neurogastroenterol Motil. 2008;20(Suppl 1):54-63. [PubMed]
23. Dey I, Lejeune M, Chadee K. Prostaglandin E2 receptor distribution and function in the gastrointestinal tract. Br J Pharmacol. 2006;149:611-623. [PMC free article] [PubMed]
24. Mizumori M, Akiba Y, Kaunitz JD. Lubiprostone stimulates duodenal bicarbonate secretion in rats. Dig Dis Sci. 2009;54:2063-2069. [PMC free article] [PubMed]
25. Cuthbert AW. Lubiprostone targets prostanoid EP receptors in ovine airways. Br J Pharmacol. 2011;162:508-520. [PMC free article] [PubMed]
26. Choi S, Yeum CH, Chang IY, You HJ, Park JS, Jeong HS, So I, Kim KW, Jun JY. Activating of ATP-dependent K channels comprised of K(ir) 6.2 and SUR 2B by PGE through EP2 receptor in cultured interstitial cells of Cajal from murine small intestine. Cell Physiol Biochem. 2006;18:187-198. [PubMed]
27. Shahi PK, Choi S, Jeong YJ, Park CG, So I, Jun JY. Basal cGMP regulates the resting pacemaker potential frequency of cultured mouse colonic interstitial cells of Cajal. Naunyn Schmiedebergs Arch Pharmacol. 2014;387:641-648. [PubMed]
28. Fujita A, Takeuchi T, Saitoh N, Hanai J, Hata F. Expression of Ca -activated K channels, SK3, in the interstitial cells of Cajal in the gastrointestinal tract. Am J Physiol Cell Physiol. 2001;281:C1727-C1733. [PubMed]
29. Lyford GL, Farrugia G. Ion channels in gastrointestinal smooth muscle and interstitial cells of Cajal. Curr Opin Pharmacol. 2003;3:583-587. [PubMed]
30. Nakayama S, Ohya S, Liu HN, Watanabe T, Furuzono S, Wang J, Nishizawa Y, Aoyama M, Murase N, Matsubara T, Ito Y, Imaizumi Y, Kajioka S. Sulphonylurea receptors differently modulate ICC pacemaker Ca activity and smooth muscle contractility. J Cell Sci. 2005;118:4163-4173. [PubMed]
31. Park CG, Kim YD, Kim MY, Kim JS, Choi S, Yeum CH, Parajuli SP, Park JS, Jeong HS, So I, Kim KW, Jun JY. Inhibition of pacemaker currents by nitric oxide via activation of ATP-sensitive K channels in cultured interstitial cells of Cajal from the mouse small intestine. Naunyn Schmiedebergs Arch Pharmacol. 2007;376:175-184. [PubMed]
32. Misiewicz JJ, Connell AM, Pontes FA. Comparison of the effect of meals and prostigmine on the proximal and distal colon in patients with and without diarrhoea. Gut. 1966;7:468-473. [PMC free article] [PubMed]