Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Izquierdo Garcia, Jose L ^a   Cai, Larry M ^a   Chaumeil, Myriam M ^a   Eriksson, Pia ^a   Robinson, Aaron E ^a   Pieper, Russell O ^a   Phillips, Joanna J ^a   Ronen, Sabrina M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYGLUTARIC ACID; 2 OXOGLUTARIC ACID; GLUTAMIC ACID; GLUTAMINE; ISOCITRATE DEHYDROGENASE 1; PYRUVATE CARBOXYLASE; PYRUVATE DEHYDROGENASE; PYRUVIC ACID; ISOCITRATE DEHYDROGENASE;

ARTICLE; ASTROCYTE; CARCINOGENESIS; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENETIC CODE; GLIOMA; HETEROZYGOTE; HUMAN; HUMAN CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WILD TYPE; BRAIN TUMOR; ENZYMOLOGY; GENETICS; METABOLISM; MUTATION; TUMOR CELL LINE;

BRAIN NEOPLASMS; CELL LINE, TUMOR; GLIOMA; HUMANS; ISOCITRATE DEHYDROGENASE; MUTATION; PYRUVATE CARBOXYLASE;

EID: 84907195343     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108289     Document Type: Article

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