Mitogen-activated protein kinase-activated protein kinase 2 deficiency reduces insulin sensitivity in high-fat diet-fed mice

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  De Boer, Jan Freark ^a   Dikkers, Arne ^a   Jurdzinski, Angelika ^a   Felden, Johann Von ^b   Gaestel, Matthias ^b   Bavendiek, Udo ^b   Tietge, Uwe J F ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FATTY ACID; GLUCOSE TRANSPORTER 4; GLYCEROL; HIGH DENSITY LIPOPROTEIN; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; MONOCYTE CHEMOTACTIC PROTEIN 1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; CCL2 PROTEIN, MOUSE; MAP-KINASE-ACTIVATED KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; SLC2A4 PROTEIN, MOUSE;

ABDOMINAL FAT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CD3E GENE; CELL INFILTRATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DYSLIPIDEMIA; ENZYME DEFICIENCY; FATTY ACID BLOOD LEVEL; GENE; GENE EXPRESSION; GLUCOSE TOLERANCE; GLUT4 GENE; GLYCEROL BLOOD LEVEL; IL6 GENE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIVER WEIGHT; MACROPHAGE; MALE; MCP 1 GENE; MGL 1 GENE; MGL 2 GENE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; TNF ALPHA GENE; TRIACYLGLYCEROL BLOOD LEVEL; ADIPOSE TISSUE; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; DEFICIENCY; GENETICS; GLUCOSE TOLERANCE TEST; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LIPID DIET; LIVER; METABOLISM; PATHOLOGY;

MUS;

ABDOMINAL FAT; ADIPOSE TISSUE; ANIMALS; CHEMOKINE CCL2; CHOLESTEROL; DIET, HIGH-FAT; DYSLIPIDEMIAS; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 4; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907193950     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106300     Document Type: Article

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