Modeling toxicodynamic effects of trichloroethylene on liver in mouse model of autoimmune hepatitis

Toxicology and Applied Pharmacology

Volumn 279, Issue 3, 2014, Pages 284-293

  Gilbert, Kathleen M ^a   Reisfeld, Brad ^b   Zurlinden, Todd J ^b   Kreps, Meagan N ^a   Erickson, Stephen W ^a   Blossom, Sarah J ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

IL 6; Immunotoxicity; Liver; Modeling; Trichloroethylene

Indexed keywords

CXCL1 CHEMOKINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOPROTEIN GP 130; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE ELASTASE; OSTEOPONTIN; SERUM AMYLOID A; TRANSCRIPTION FACTOR EGR 1; TRICHLOROETHYLENE; TUMOR NECROSIS FACTOR ALPHA; DRINKING WATER; EARLY GROWTH RESPONSE FACTOR 1; INTERLEUKIN 6 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE HEPATITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE EXPRESSION; LIVER HISTOLOGY; LIVER PROTECTION; LIVER TOXICITY; MACROPHAGE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL MODEL; ANTIBODY PRODUCTION; AUTOIMMUNITY; CLINICAL EVALUATION; HISTOPATHOLOGY; HUMAN; IMMUNE SYSTEM; IMMUNOTOXICITY; INFLAMMATORY CELL; LINEAR REGRESSION ANALYSIS; LIVER REGENERATION; LONG TERM EXPOSURE; LONGITUDINAL STUDY; TISSUE REPAIR; TOXICITY TESTING;

IL-6; IMMUNOTOXICITY; LIVER; MODELING; TRICHLOROETHYLENE;

ALGORITHMS; ANIMALS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION; HEALTH STATUS; HEPATITIS, AUTOIMMUNE; INTERLEUKIN-6; LIVER; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED MRL LPR; MICE, KNOCKOUT; MODELS, BIOLOGICAL; REAL-TIME POLYMERASE CHAIN REACTION; TRICHLOROETHYLENE; WATER POLLUTANTS;

EID: 84907184017     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.07.003     Document Type: Article

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