Time- and concentration-dependent genomic responses of the rat airway to inhaled nickel subsulfide

Toxicology and Applied Pharmacology

Volumn 279, Issue 3, 2014, Pages 441-454

  Efremenko, A Y ^a   Campbell, J L ^a   Dodd, D E ^a   Oller, A R ^b   Clewell, H J ^a  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b NiPERA Inc   (United States)

Author keywords

Carcinogenicity; Gene expression; Inhalation; Nickel subsulfide

Indexed keywords

LACTATE DEHYDROGENASE; NICKEL SUBSULFIDE; PROTEIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUTOPSY; CARCINOGENICITY; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; DRUG CARCINOGENICITY; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION; GENOMICS; HISTOPATHOLOGY; IN VIVO STUDY; MALE; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION; TARGET CELL; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; ADAPTATION; AIRWAY; ANIMAL MODEL; ANIMAL TISSUE; BIOASSAY; BODY WEIGHT; CELL PROLIFERATION; CHRONIC TOXICITY; CONCENTRATION RESPONSE; ENVIRONMENTAL PARAMETERS; EXPOSURE; IMMUNE SYSTEM; INFLAMMATION; INHALATION; LUNG; LUNG CARCINOGENESIS; LUNG LAVAGE; MICRODISSECTION; MOUSE; RISK ASSESSMENT; SIGNAL TRANSDUCTION; TIME;

CARCINOGENICITY; GENE EXPRESSION; INHALATION; NICKEL SUBSULFIDE;

ANIMALS; APOPTOSIS; BENCHMARKING; BODY WEIGHT; BRONCHOALVEOLAR LAVAGE FLUID; CARCINOGENS; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION; INFLAMMATION; INHALATION EXPOSURE; LUNG; MALE; MICROARRAY ANALYSIS; MICROSCOPY, ELECTRON, TRANSMISSION; MUTAGENS; NICKEL; RATS; RATS, INBRED F344; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84907174276     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.06.007     Document Type: Article

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