Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: The Vitality 90+ Study

BMC Medical Genomics

Volumn 7, Issue 1, 2014, Pages

  Jylhävä, Juulia ^a,b   Raitanen, Jani ^a,c   Marttila, Saara ^a,b   Hervonen, Antti ^a,b   Jylhä, Marja ^a,b   Hurme, Mikko ^a,b,d  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b Jyvaskyla University   (Finland)

^c UKK INSTITUTE FOR HEALTH PROMOTION RESEARCH   (Finland)

^d FIMLAB LABORATORIES   (Finland)

Author keywords

Aging; Biomarkers; Cox model; Mortality; Penalized regression; Transcriptomics

Indexed keywords

CD27 ANTIGEN; CD28 ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; PHOSPHATIDYLINOSITOL 3 KINASE;

AGE DISTRIBUTION; AGED; AGING; ARTICLE; BIOINFORMATICS; BODY MASS; CAUSE OF DEATH; CELL CYCLE ASSAY; CELL DEATH; CELL SURVIVAL; CELLULAR IMMUNITY; CELLULAR STRESS RESPONSE; COHORT ANALYSIS; CONTROLLED STUDY; DATA ANALYSIS; DNA DAMAGE; DNA DETERMINATION; FEMALE; FOLLOW UP; FRAIL ELDERLY; GENE; GENE EXPRESSION PROFILING; GENE MAPPING; GENE REGULATORY NETWORK; GENETIC ALGORITHM; GENETIC ASSOCIATION; GENETIC CORRELATION; GENETIC MARKER; GENOMICS; GERIATRIC PATIENT; HUMAN; HUMORAL IMMUNITY; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MITOCHONDRIAL RESPIRATION; MORTALITY; NFKAPPAB GENE; PREDICTIVE VALUE; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RIDGE REGRESSION MODEL; SIGNAL TRANSDUCTION; STATISTICAL MODEL; TRANSCRIPTOMICS; VERY ELDERLY; GENETICS; LONGEVITY;

AGED, 80 AND OVER; AGING; COHORT STUDIES; FEMALE; GENE EXPRESSION PROFILING; GENOMICS; HUMANS; LONGEVITY; MALE; MORTALITY; PROGNOSIS;

EID: 84907173952     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-7-54     Document Type: Article

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