메뉴 건너뛰기




Volumn 804, Issue , 2014, Pages 147-160

Autophagy in osteosarcoma

Author keywords

Autophagy; Clinical trials; Hydroxychloroquine; Osteosarcoma; Pro tumorigenic; Tumor suppressor

Indexed keywords

BECLIN 1; CANNABINOID; CISPLATIN; DOXORUBICIN; EVEROLIMUS; GEMCITABINE; HIGH MOBILITY GROUP B1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; METHOTREXATE; NATURAL PRODUCT; OBATOCLAX; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; RAPAMYCIN; RIDAFOROLIMUS; STAT3 PROTEIN; TRANSCRIPTION FACTOR E2F1; ANTINEOPLASTIC ANTIMETABOLITE; DEOXYCYTIDINE; DRUG DERIVATIVE; HYDROXYCHLOROQUINE;

EID: 84907168940     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-04843-7_8     Document Type: Article
Times cited : (26)

References (55)
  • 1
    • 77953672971 scopus 로고    scopus 로고
    • The role of Fas/FasL in the metastatic potential of osteosarcoma and targeting this pathway for the treatment of osteosarcoma lung metastases
    • Gordon N, Kleinerman ES (2009) The role of Fas/FasL in the metastatic potential of osteosarcoma and targeting this pathway for the treatment of osteosarcoma lung metastases. Cancer Treat Res 152:497-508. doi: 10.1007/978-1-4419-0284-9_29
    • (2009) Cancer Treat Res , vol.152 , pp. 497-508
    • Gordon, N.1    Kleinerman, E.S.2
  • 3
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • Gozuacik D, Kimchi A (2004) Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23(16):2891-2906. doi: 10.1038/sj.onc.1207521
    • (2004) Oncogene , vol.23 , Issue.16 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 4
    • 79955677000 scopus 로고    scopus 로고
    • Autophagic cell death: Loch Ness monster or endangered species?
    • Shen HM, Codogno P (2011) Autophagic cell death: Loch Ness monster or endangered species? Autophagy 7(5):457-465
    • (2011) Autophagy , vol.7 , Issue.5 , pp. 457-465
    • Shen, H.M.1    Codogno, P.2
  • 6
    • 65349191918 scopus 로고    scopus 로고
    • Programmed cell death and cancer
    • Sun Y, Peng ZL (2009) Programmed cell death and cancer. Postgrad Med J 85(1001):134-140. doi: 10.1136/pgmj.2008.072629
    • (2009) Postgrad Med J , vol.85 , Issue.1001 , pp. 134-140
    • Sun, Y.1    Peng, Z.L.2
  • 7
    • 80052697287 scopus 로고    scopus 로고
    • The role of autophagy in cancer: Therapeutic implications
    • Yang ZJ, Chee CE, Huang S, Sinicrope FA (2011) The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther 10(9):1533-1541. doi: 10.1158/1535-7163.MCT-11-0047
    • (2011) Mol Cancer Ther , vol.10 , Issue.9 , pp. 1533-1541
    • Yang, Z.J.1    Chee, C.E.2    Huang, S.3    Sinicrope, F.A.4
  • 8
    • 84864805916 scopus 로고    scopus 로고
    • Autophagy and cancer-issues we need to digest
    • Liu EY, Ryan KM (2012) Autophagy and cancer-issues we need to digest. J Cell Sci 125(Pt 10):2349-2358. doi: 10.1242/jcs.093708
    • (2012) J Cell Sci , vol.125 , pp. 2349-2358
    • Liu, E.Y.1    Ryan, K.M.2
  • 9
    • 77953431643 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signaling and cancer treatment
    • Huber A, Rubio A, Loewith RJ (2009) Mammalian target of rapamycin signaling and cancer treatment. Cancer Chemother Rev 4(4):210-223
    • (2009) Cancer Chemother Rev , vol.4 , Issue.4 , pp. 210-223
    • Huber, A.1    Rubio, A.2    Loewith, R.J.3
  • 11
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang R, Zeh HJ, Lotze MT, Tang D (2011) The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18(4):571-580. doi: 10.1038/cdd.2010.191
    • (2011) Cell Death Differ , vol.18 , Issue.4 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 13
    • 39049194057 scopus 로고    scopus 로고
    • The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
    • Furuya N, Yu J, Byfield M, Pattingre S, Levine B (2005) The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1(1):46-52
    • (2005) Autophagy , vol.1 , Issue.1 , pp. 46-52
    • Furuya, N.1    Yu, J.2    Byfield, M.3    Pattingre, S.4    Levine, B.5
  • 14
    • 67349232611 scopus 로고    scopus 로고
    • Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function
    • Ciechomska IA, Goemans GC, Skepper JN, Tolkovsky AM (2009) Bcl-2 complexed with Beclin-1 maintains full anti-apoptotic function. Oncogene 28(21):2128-2141. doi: 10.1038/ onc.2009.60
    • (2009) Oncogene , vol.28 , Issue.21 , pp. 2128-2141
    • Ciechomska, I.A.1    Goemans, G.C.2    Skepper, J.N.3    Tolkovsky, A.M.4
  • 15
    • 67349171677 scopus 로고    scopus 로고
    • Beclin 1: A BH3-only protein that fails to induce apoptosis
    • Boya P, Kroemer G (2009) Beclin 1: a BH3-only protein that fails to induce apoptosis. Oncogene 28(21):2125-2127. doi: 10.1038/onc.2009.83
    • (2009) Oncogene , vol.28 , Issue.21 , pp. 2125-2127
    • Boya, P.1    Kroemer, G.2
  • 16
    • 58049192897 scopus 로고    scopus 로고
    • Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase
    • Sun Q, Fan W, Chen K, Ding X, Chen S, Zhong Q (2008) Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase. Proc Natl Acad Sci U S A 105(49):19211-19216. doi: 10.1073/pnas.0810452105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.49 , pp. 19211-19216
    • Sun, Q.1    Fan, W.2    Chen, K.3    Ding, X.4    Chen, S.5    Zhong, Q.6
  • 17
    • 70149114818 scopus 로고    scopus 로고
    • c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated ewing sarcoma cells
    • Lorin S, Borges A, Dos Santos LR, Souquere S, Pierron G, Ryan KM, Codogno P, Djavaheri- Mergny M (2009) c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated ewing sarcoma cells. Cancer Res 69(17):6924-6931, http://dx.doi.org/ 10.1158/0008-5472.CAN-09-1270
    • (2009) Cancer Res , vol.69 , Issue.17 , pp. 6924-6931
    • Lorin, S.1    Borges, A.2    Dos Santos, L.R.3    Souquere, S.4    Pierron, G.5    Ryan, K.M.6    Codogno, P.7    Djavaheri-Mergny, M.8
  • 18
    • 59649092634 scopus 로고    scopus 로고
    • Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62
    • Pursiheimo JP, Rantanen K, Heikkinen PT, Johansen T, Jaakkola PM (2009) Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62. Oncogene 28(3):334-344. doi: 10.1038/ onc.2008.392
    • (2009) Oncogene , vol.28 , Issue.3 , pp. 334-344
    • Pursiheimo, J.P.1    Rantanen, K.2    Heikkinen, P.T.3    Johansen, T.4    Jaakkola, P.M.5
  • 19
    • 84862277154 scopus 로고    scopus 로고
    • Hypoxia-induced autophagy: A new player in cancer immunotherapy?
    • Noman MZ, Janji B, Berchem G, Mami-Chouaib F, Chouaib S (2012) Hypoxia-induced autophagy: a new player in cancer immunotherapy? Autophagy 8(4):704-706. doi: 10.4161/ auto.19572
    • (2012) Autophagy , vol.8 , Issue.4 , pp. 704-706
    • Noman, M.Z.1    Janji, B.2    Berchem, G.3    Mami-Chouaib, F.4    Chouaib, S.5
  • 21
    • 80052060417 scopus 로고    scopus 로고
    • RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT
    • Coupienne I, Fettweis G, Piette J (2011) RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. Lasers Surg Med 43(7):557-564. doi: 10.1002/ lsm.21088
    • (2011) Lasers Surg Med , vol.43 , Issue.7 , pp. 557-564
    • Coupienne, I.1    Fettweis, G.2    Piette, J.3
  • 22
    • 85046981421 scopus 로고    scopus 로고
    • Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma
    • Huang J, Liu K, Yu Y, Xie M, Kang R, Vernon P, Cao L, Tang D, Ni J (2012) Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma. Autophagy 8(2):275-277. doi: 10.4161/auto.8.2.18940
    • (2012) Autophagy , vol.8 , Issue.2 , pp. 275-277
    • Huang, J.1    Liu, K.2    Yu, Y.3    Xie, M.4    Kang, R.5    Vernon, P.6    Cao, L.7    Tang, D.8    Ni, J.9
  • 24
    • 84872520058 scopus 로고    scopus 로고
    • Inhibit autophagy, STAT!
    • Wong W (2013) Inhibit autophagy, STAT! Sci Signal 6(256):ec4, http://dx.doi.org/ 10.1126/ scisignal.2003913
    • (2013) Sci Signal , vol.6 , Issue.256
    • Wong, W.1
  • 25
    • 79953153832 scopus 로고    scopus 로고
    • Autophagy and tumorigenesis
    • Roy S, Debnath J (2010) Autophagy and tumorigenesis. Semin Immunopathol 32(4):383-396. doi: 10.1007/s00281-010-0213-0
    • (2010) Semin Immunopathol , vol.32 , Issue.4 , pp. 383-396
    • Roy, S.1    Debnath, J.2
  • 26
    • 77950509348 scopus 로고    scopus 로고
    • Autophagy and tumorigenesis
    • Chen N, Debnath J (2010) Autophagy and tumorigenesis. FEBS Lett 584(7):1427-1435. doi: 10.1016/j.febslet.2009.12.034
    • (2010) FEBS Lett , vol.584 , Issue.7 , pp. 1427-1435
    • Chen, N.1    Debnath, J.2
  • 28
    • 80051668850 scopus 로고    scopus 로고
    • The dual role of autophagy in cancer
    • Eskelinen EL (2011) The dual role of autophagy in cancer. Curr Opin Pharmacol 11(4):294-300. doi: 10.1016/j.coph.2011.03.009
    • (2011) Curr Opin Pharmacol , vol.11 , Issue.4 , pp. 294-300
    • Eskelinen, E.L.1
  • 29
    • 84926662923 scopus 로고    scopus 로고
    • Identification of compounds that enhance and suppress autophagy
    • Akin D, Law B, Progulske-fox A, Dunn WA (2009) Identification of compounds that enhance and suppress autophagy. Autophagy 5(6):910-911
    • (2009) Autophagy , vol.5 , Issue.6 , pp. 910-911
    • Akin, D.1    Law, B.2    Progulske-Fox, A.3    Dunn, W.A.4
  • 30
    • 79960917666 scopus 로고    scopus 로고
    • Autophagy as a mediator of chemotherapy-induced cell death in cancer
    • Notte A, Leclere L, Michiels C (2011) Autophagy as a mediator of chemotherapy-induced cell death in cancer. Biochem Pharmacol 82(5):427-434. doi: 10.1016/j.bcp.2011.06.015
    • (2011) Biochem Pharmacol , vol.82 , Issue.5 , pp. 427-434
    • Notte, A.1    Leclere, L.2    Michiels, C.3
  • 31
    • 11144221007 scopus 로고    scopus 로고
    • Apoptotic and autophagic cell death induced by histone deacetylase inhibitors
    • Shao Y, Gao Z, Marks PA, Jiang X (2004) Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci U S A 101(52):18030-18035. doi: 10.1073/ pnas.0408345102
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.52 , pp. 18030-18035
    • Shao, Y.1    Gao, Z.2    Marks, P.A.3    Jiang, X.4
  • 32
    • 68049104247 scopus 로고    scopus 로고
    • Autophagy: Molecular machinery, regulation, and implications for renal pathophysiology
    • Periyasamy-Thandavan S, Jiang M, Schoenlein P, Dong Z (2009) Autophagy: molecular machinery, regulation, and implications for renal pathophysiology. Am J Physiol Renal Physiol 297(2):F244-F256. doi: 10.1152/ajprenal.00033.2009
    • (2009) Am J Physiol Renal Physiol , vol.297 , Issue.2 , pp. 244-256
    • Periyasamy-Thandavan, S.1    Jiang, M.2    Schoenlein, P.3    Dong, Z.4
  • 34
    • 77957660865 scopus 로고    scopus 로고
    • Dasatinib induces autophagic cell death in human ovarian cancer
    • Le XF, Mao W, Lu Z, Carter BZ, Bast RC Jr (2010) Dasatinib induces autophagic cell death in human ovarian cancer. Cancer 116(21):4980-4990. doi: 10.1002/cncr.25426
    • (2010) Cancer , vol.116 , Issue.21 , pp. 4980-4990
    • Le, X.F.1    Mao, W.2    Lu, Z.3    Carter, B.Z.4    Bast, R.C.5
  • 35
    • 33846240526 scopus 로고    scopus 로고
    • Sequestosome 1/p62-more than just a scaffold
    • Seibenhener ML, Geetha T, Wooten MW (2007) Sequestosome 1/p62-more than just a scaffold. FEBS Lett 581(2):175-179. doi: 10.1016/j.febslet.2006.12.027
    • (2007) FEBS Lett , vol.581 , Issue.2 , pp. 175-179
    • Seibenhener, M.L.1    Geetha, T.2    Wooten, M.W.3
  • 36
    • 77950495123 scopus 로고    scopus 로고
    • Physiological significance of selective degradation of p62 by autophagy
    • Komatsu M, Ichimura Y (2010) Physiological significance of selective degradation of p62 by autophagy. FEBS Lett 584(7):1374-1378. doi: 10.1016/j.febslet.2010.02.017
    • (2010) FEBS Lett , vol.584 , Issue.7 , pp. 1374-1378
    • Komatsu, M.1    Ichimura, Y.2
  • 37
    • 79953153831 scopus 로고    scopus 로고
    • Selective degradation of p62 by autophagy
    • Ichimura Y, Komatsu M (2010) Selective degradation of p62 by autophagy. Semin Immunopathol 32(4):431-436. doi: 10.1007/s00281-010-0220-1
    • (2010) Semin Immunopathol , vol.32 , Issue.4 , pp. 431-436
    • Ichimura, Y.1    Komatsu, M.2
  • 38
    • 84875722622 scopus 로고    scopus 로고
    • Molecular aspects of cancer cell resistance to chemotherapy
    • Rebucci M, Michiels C (2013) Molecular aspects of cancer cell resistance to chemotherapy. Biochem Pharmacol 85(9):1219-1226. doi: 10.1016/j.bcp.2013.02.017
    • (2013) Biochem Pharmacol , vol.85 , Issue.9 , pp. 1219-1226
    • Rebucci, M.1    Michiels, C.2
  • 39
    • 84887116310 scopus 로고    scopus 로고
    • Overcoming resistance to targeted anticancer drugs
    • Doroshow JH (2013) Overcoming resistance to targeted anticancer drugs. N Engl J Med 369(19):1852-1853. doi: 10.1056/NEJMe1311325
    • (2013) N Engl J Med , vol.369 , Issue.19 , pp. 1852-1853
    • Doroshow, J.H.1
  • 40
    • 23844481408 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in cancer chemotherapy
    • Luqmani YA (2005) Mechanisms of drug resistance in cancer chemotherapy. Med Princ Pract 14(Suppl 1):35-48. doi: 10.1159/000086183
    • (2005) Med Princ Pract , vol.14 , pp. 35-48
    • Luqmani, Y.A.1
  • 41
    • 73949135792 scopus 로고    scopus 로고
    • Mechanisms of multidrug resistance in cancer
    • Gillet JP, Gottesman MM (2010) Mechanisms of multidrug resistance in cancer. Methods Mol Biol 596:47-76. doi: 10.1007/978-1-60761-416-6_4
    • (2010) Methods Mol Biol , vol.596 , pp. 47-76
    • Gillet, J.P.1    Gottesman, M.M.2
  • 42
    • 80054912018 scopus 로고    scopus 로고
    • Cell death pathology: The war against cancer
    • Rufini A, Melino G (2011) Cell death pathology: the war against cancer. Biochem Biophys Res Commun 414(3):445-450, http://dx.doi.org/ 10.1016/j.bbrc.2011.09.110
    • (2011) Biochem Biophys Res Commun , vol.414 , Issue.3 , pp. 445-450
    • Rufini, A.1    Melino, G.2
  • 43
    • 33846799065 scopus 로고    scopus 로고
    • Autophagymediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells
    • Meschini S, Condello M, Marra M, Formisano G, Federici E, Arancia G (2007) Autophagymediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells. Toxicol In Vitro 21(2):197-203. doi: 10.1016/j.tiv.2006.09.007
    • (2007) Toxicol In Vitro , vol.21 , Issue.2 , pp. 197-203
    • Meschini, S.1    Condello, M.2    Marra, M.3    Formisano, G.4    Federici, E.5    Arancia, G.6
  • 44
    • 58149104056 scopus 로고    scopus 로고
    • The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells
    • Meschini S, Condello M, Calcabrini A, Marra M, Formisano G, Lista P, De Milito A, Federici E, Arancia G (2008) The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells. Autophagy 4(8):1020-1033
    • (2008) Autophagy , vol.4 , Issue.8 , pp. 1020-1033
    • Meschini, S.1    Condello, M.2    Calcabrini, A.3    Marra, M.4    Formisano, G.5    Lista, P.6    De Milito, A.7    Federici, E.8    Arancia, G.9
  • 46
    • 79851515032 scopus 로고    scopus 로고
    • Dihydroptychantol A, a macrocyclic bisbibenzyl derivative, induces autophagy and following apoptosis associated with p53 pathway in human osteosarcoma U2OS cells
    • Li X, Wu WK, Sun B, Cui M, Liu S, Gao J, Lou H (2011) Dihydroptychantol A, a macrocyclic bisbibenzyl derivative, induces autophagy and following apoptosis associated with p53 pathway in human osteosarcoma U2OS cells. Toxicol Appl Pharmacol 251(2):146-154. doi: 10.1016/j.taap.2010.12.007
    • (2011) Toxicol Appl Pharmacol , vol.251 , Issue.2 , pp. 146-154
    • Li, X.1    Wu, W.K.2    Sun, B.3    Cui, M.4    Liu, S.5    Gao, J.6    Lou, H.7
  • 47
    • 83755206343 scopus 로고    scopus 로고
    • Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin
    • Ma D, Tremblay P, Mahngar K, Collins J, Hudlicky T, Pandey S (2011) Selective cytotoxicity against human osteosarcoma cells by a novel synthetic C-1 analogue of 7-deoxypancratistatin is potentiated by curcumin. PLoS One 6(12). http://dx.doi.org/10.1371/journal.pone.0028780
    • (2011) PLoS One , vol.6 , Issue.12
    • Ma, D.1    Tremblay, P.2    Mahngar, K.3    Collins, J.4    Hudlicky, T.5    Pandey, S.6
  • 49
    • 84863576915 scopus 로고    scopus 로고
    • Cannabinoid-associated cell death mechanisms in tumor models (review)
    • Calvaruso G, Pellerito O, Notaro A, Giuliano M (2012) Cannabinoid-associated cell death mechanisms in tumor models (review). Int J Oncol 41(2):407-413, http://dx.doi.org/ 10.3892/ ijo.2012.1476
    • (2012) Int J Oncol , vol.41 , Issue.2 , pp. 407-413
    • Calvaruso, G.1    Pellerito, O.2    Notaro, A.3    Giuliano, M.4
  • 50
    • 77952525706 scopus 로고    scopus 로고
    • The BH3-mimetic GX15-070 induces autophagy, potentiates the cytotoxicity of carboplatin and 5-fluorouracil in esophageal carcinoma cells
    • Pan J, Cheng C, Verstovsek S, Chen Q, Jin Y, Cao Q (2010) The BH3-mimetic GX15-070 induces autophagy, potentiates the cytotoxicity of carboplatin and 5-fluorouracil in esophageal carcinoma cells. Cancer Lett 293(2):167-174. doi: 10.1016/j.canlet.2010.01.006
    • (2010) Cancer Lett , vol.293 , Issue.2 , pp. 167-174
    • Pan, J.1    Cheng, C.2    Verstovsek, S.3    Chen, Q.4    Jin, Y.5    Cao, Q.6
  • 52
    • 54249104991 scopus 로고    scopus 로고
    • Autophagy: A novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model
    • Lambert LA, Qiao N, Hunt KK, Lambert DH, Mills GB, Meijer L, Keyomarsi K (2008) Autophagy: a novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model. Cancer Res 68(19):7966-7974, http://dx.doi.org/ 10.1158/0008-5472. CAN-08-1333
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 7966-7974
    • Lambert, L.A.1    Qiao, N.2    Hunt, K.K.3    Lambert, D.H.4    Mills, G.B.5    Meijer, L.6    Keyomarsi, K.7
  • 53
    • 77149172547 scopus 로고    scopus 로고
    • Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity
    • Zhang Z, Shao Z, Xiong L, Che B, Deng C, Xu W (2009) Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity. J Huazhong Univ Sci Technolog Med Sci 29(6):737-740. doi: 10.1007/s11596-009-0613-3
    • (2009) J Huazhong Univ Sci Technolog Med Sci , vol.29 , Issue.6 , pp. 737-740
    • Zhang, Z.1    Shao, Z.2    Xiong, L.3    Che, B.4    Deng, C.5    Xu, W.6
  • 54
    • 77955465161 scopus 로고    scopus 로고
    • Aerosol therapy for the treatment of osteosarcoma lung metastases: Targeting the Fas/FasL pathway and rationale for the use of gemcitabine
    • Gordon N, Kleinerman ES (2010) Aerosol therapy for the treatment of osteosarcoma lung metastases: targeting the Fas/FasL pathway and rationale for the use of gemcitabine. J Aerosol Med Pulm Drug Deliv 23(4):189-196. doi: 10.1089/jamp.2009.0812
    • (2010) J Aerosol Med Pulm Drug Deliv , vol.23 , Issue.4 , pp. 189-196
    • Gordon, N.1    Kleinerman, E.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.