The angiotensin II type 1 receptor (AT1R) closely interacts with large conductance voltage- and Ca2+-activated K+(BK) channels and inhibits their activity independent of G-protein activation

Journal of Biological Chemistry

Volumn 289, Issue 37, 2014, Pages 25678-25689

  Zhang, Zhu ^a   Li, Min ^a   Lu, Rong ^a   Alioua, Abderrahmane ^a   Stefani, Enrico ^a   Toro, Ligia ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD PRESSURE; CELL MEMBRANES; CELLS; CHEMICAL ACTIVATION; COBALT COMPOUNDS; CYTOLOGY;

CO-IMMUNOPRECIPITATIONS; G PROTEIN ACTIVATION; INTERMOLECULAR INTERACTIONS; MACROMOLECULAR COMPLEXES; MOLECULAR MECHANISM; PROTEIN-PROTEIN INTERACTIONS; TRANSFECTED CELLS; VOLTAGE SENSITIVITY;

PROTEINS;

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CYAN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; YELLOW FLUORESCENT PROTEIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; GREEN FLUORESCENT PROTEIN; LOSARTAN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; RENAL ARTERY; SMOOTH MUSCLE FIBER; ANIMAL; CALCIUM SIGNALING; DRUG EFFECTS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELL LINE; KIDNEY ARTERY; METABOLISM; MUSCLE CELL; PATCH CLAMP TECHNIQUE;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; CALCIUM SIGNALING; FLUORESCENCE RESONANCE ENERGY TRANSFER; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; LOSARTAN; MUSCLE CELLS; PATCH-CLAMP TECHNIQUES; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RENAL ARTERY;

EID: 84907168824     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.595603     Document Type: Article

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