메뉴 건너뛰기




Volumn 42, Issue 3, 2014, Pages 757-760

PSEN1 and PSEN2 gene expression in Alzheimer's disease brain: A new approach

Author keywords

Alzheimer's disease; brain; gene expression; presenilin 1; presenilin 2; secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; PRESENILIN 1; PRESENILIN 2; RNA; ARABIDOPSIS PROTEIN; MARNERAL SYNTHASE, ARABIDOPSIS; MUTASE;

EID: 84907141350     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-140033     Document Type: Article
Times cited : (37)

References (13)
  • 1
    • 0035081475 scopus 로고    scopus 로고
    • Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein
    • Selkoe DJ (2001) Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J Alzheimers Dis 3, 75-80.
    • (2001) J Alzheimers Dis , vol.3 , pp. 75-80
    • Selkoe, D.J.1
  • 2
    • 84888133742 scopus 로고    scopus 로고
    • Epigenetic changes in the progression of Alzheimer's disease
    • Bradley-Whitman MA, Lovell MA (2013) Epigenetic changes in the progression of Alzheimer's disease. Mech Ageing Dev 134, 486-495.
    • (2013) Mech Ageing Dev , vol.134 , pp. 486-495
    • Bradley-Whitman, M.A.1    Lovell, M.A.2
  • 3
    • 84899019792 scopus 로고    scopus 로고
    • Amyloid-and tau: The trigger and bullet in Alzheimer disease pathogenesis
    • Bloom GS(2014) Amyloid-and tau: The trigger and bullet in Alzheimer disease pathogenesis. JAMA Neurol 71, 505-508.
    • (2014) JAMA Neurol , vol.71 , pp. 505-508
    • Bloom, G.S.1
  • 5
    • 84860015622 scopus 로고    scopus 로고
    • Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified c-secretase complexes
    • Cacquevel M, Aeschbach L, Houacine J, Fraering PC (2012) Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified c-secretase complexes. Plos One 7, e35133.
    • (2012) Plos One , vol.7 , pp. e35133
    • Cacquevel, M.1    Aeschbach, L.2    Houacine, J.3    Fraering, P.C.4
  • 7
    • 13244299288 scopus 로고    scopus 로고
    • Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in A-42/40 ratios
    • Walker ES, Martinez M, Brunkan AL, Goate A (2005) Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in A-42/40 ratios. J Neurochem 92, 294-301.
    • (2005) J Neurochem , vol.92 , pp. 294-301
    • Walker, E.S.1    Martinez, M.2    Brunkan, A.L.3    Goate, A.4
  • 8
    • 82255182140 scopus 로고    scopus 로고
    • Increased expression of PS1 is sufficient to elevate the level and activity of c-secretase in vivo
    • Li T, Li YM, Ahn K, Price DL, Sisodia SS, Wong PC (2011) Increased expression of PS1 is sufficient to elevate the level and activity of c-secretase in vivo. PLoS ONE 6, e28179.
    • (2011) PLoS ONE , vol.6 , pp. e28179
    • Li, T.1    Li, Y.M.2    Ahn, K.3    Price, D.L.4    Sisodia, S.S.5    Wong, P.C.6
  • 10
    • 0037207059 scopus 로고    scopus 로고
    • Presenilins in the heart: Presenilin-2 expression is increased by lowglucose and by hypoxia in cardiac cells
    • Mohuczy D, Qian K, Phillips MI (2002) Presenilins in the heart: Presenilin-2 expression is increased by lowglucose and by hypoxia in cardiac cells. Regul Pept 110, 1-7.
    • (2002) Regul Pept , vol.110 , pp. 1-7
    • Mohuczy, D.1    Qian, K.2    Phillips, M.I.3
  • 11
    • 84856060315 scopus 로고    scopus 로고
    • Mutant presenilin 2 increases a-secretase activity through reactive oxygen species dependent activation of extracellular signal regulated kinase
    • Park MH, Choi DY, Jin HW, Yoo HS, Han JY, Oh KW, Han SB, Hwang DY, Hong JT (2012) Mutant presenilin 2 increases a-secretase activity through reactive oxygen species dependent activation of extracellular signal regulated kinase. J Neuropathol Exp Neurol 71, 130-139.
    • (2012) J Neuropathol Exp Neurol , vol.71 , pp. 130-139
    • Park, M.H.1    Choi, D.Y.2    Jin, H.W.3    Yoo, H.S.4    Han, J.Y.5    Oh, K.W.6    Han, S.B.7    Hwang, D.Y.8    Hong, J.T.9
  • 13
    • 77951530055 scopus 로고    scopus 로고
    • Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease
    • Tan MG, Chua WT, Esiri MM, Smith AD, Vinters HV, Lai MK(2010) Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease. J Neurosci Res 88, 1157-1169.
    • (2010) J Neurosci Res , vol.88 , pp. 1157-1169
    • Tan, M.G.1    Chua, W.T.2    Esiri, M.M.3    Smith, A.D.4    Vinters, H.V.5    Lai, M.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.