Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis

Journal of Biomaterials Applications

Volumn 29, Issue 4, 2014, Pages 514-523

  Beenken, Karen E ^a   Smith, James K ^b   Skinner, Robert A ^a   McLaren, Sandra G ^a   Bellamy, William ^a   Gruenwald, M Johannes ^a   Spencer, Horace J ^a   Jennings, Jessica A ^b   Haggard, Warren O ^b   Smeltzer, Mark S ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b University of Memphis   (United States)

Author keywords

bone; Calcium sulfate; chitosan; daptomycin; infection; local drug delivery; osteomyelitis

Indexed keywords

ANTIBIOTICS; BACTERIOLOGY; BONE; CHITOSAN; COATINGS; CONTROLLED DRUG DELIVERY; DRIERS (MATERIALS); SULFUR COMPOUNDS; TARGETED DRUG DELIVERY;

CALCIUM SULFATE; DAPTOMYCIN; INFECTION; LOCAL DRUG DELIVERY; OSTEOMYELITIS;

CALCIUM COMPOUNDS;

CALCIUM SULFATE; CHITOSAN; DAPTOMYCIN; ANTIINFECTIVE AGENT; BIOCOMPATIBLE COATED MATERIAL; POLY(METHYL METHACRYLATE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; BONE IMPLANT; CHRONIC OSTEOMYELITIS; CONTROLLED STUDY; DEBRIDEMENT; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG EFFICACY; ELUTION; HISTOPATHOLOGY; NONHUMAN; STAPHYLOCOCCUS INFECTION; TREATMENT OUTCOME; ANIMAL; CHEMISTRY; CHRONIC DISEASE; DISEASE MODEL; MALE; MATERIALS TESTING; MICROBIOLOGY; OSTEOMYELITIS; PROSTHESIS-RELATED INFECTIONS; RABBIT; STAPHYLOCOCCAL INFECTIONS;

ANIMALS; ANTI-BACTERIAL AGENTS; CALCIUM SULFATE; CHITOSAN; CHRONIC DISEASE; COATED MATERIALS, BIOCOMPATIBLE; DAPTOMYCIN; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; MALE; MATERIALS TESTING; OSTEOMYELITIS; POLYMETHYL METHACRYLATE; PROSTHESIS-RELATED INFECTIONS; RABBITS; STAPHYLOCOCCAL INFECTIONS;

EID: 84907141235     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328214535452     Document Type: Article

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