Optimized elution of daptomycin from polymethylmethacrylate beads

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 1, 2009, Pages 264-266

  Weiss, Brian D ^a   Weiss, Elizabeth C ^a   Haggard, Warren O ^b   Evans, Richard P ^a   McLaren, Sandra G ^a   Smeltzer, Mark S ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b University of Memphis   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE CEMENT; DAPTOMYCIN; GENTAMICIN; POLYMETHACRYLIC ACID; VANCOMYCIN; XYLITOL;

ARTICLE; BIOASSAY; DRUG FORMULATION; ELUTION; POLYMERIZATION; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

BONE CEMENTS; CHEMISTRY, PHARMACEUTICAL; DAPTOMYCIN; DRUG CARRIERS; GENTAMICINS; POLYMETHYL METHACRYLATE; VANCOMYCIN; XYLITOL;

EID: 59749097857     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00258-08     Document Type: Article

References (8)

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3. McLaren, A. C., S. G. McLaren, and M. S. Smeltzer. 2006. Xylitol and glycine fillers increase permeability of PMMA to enhance elution of daptomycin. Clin. Orthop. Relat. Res. 451:25-28.
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7. Richelsoph, K. C., N. D. Webb, and W. O. Haggard. 2007. Elution behavior of daptomycin-loaded calcium sulfate pellets: a preliminary study. Clin. Orthop. Relat. Res. 461:68-73.
8. Zalavras, C. G., M. J. Patzakis, and P. Holtom. 2004. Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin. Orthop. Relat. Res. 427:86-93.