Chemical profiling and in vitro biological effects of Cardiospermum halicacabum L. (Sapindaceae) aerial parts and seeds for applications in neurodegenerative disorders

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 29, Issue 5, 2014, Pages 677-685

  Menichini, Francesco ^a   Losi, Luigi ^b   Bonesi, Marco ^a   Pugliese, Alessandro ^a   Loizzo, Monica R ^a   Tundis, Rosa ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

^b Hering Laboratori SRL   (Italy)

Author keywords

Antioxidant; Cholinesterase; GC MS; HPLC; Seeds

Indexed keywords

2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); ACETYLCHOLINESTERASE; APIGENIN; APIGETRIN; ARACHIDIC ACID; BETA AMYRIN; BETA CAROTENE; CARDIOSPERMUM HALICACABUM EXTRACT; CHLOROGENIC ACID; CHOLINESTERASE; HEXANE; LUTEOLIN; METHANOL; METHOXSALEN; METHYL 11 EICOSENOATE; METHYL ERUCATE; MONOPHENOL MONOOXYGENASE; NEOPHYTADIENE; OLEIC ACID; OSTHOLE; PHYTOL; PHYTOL ACETATE; PLANT EXTRACT; RUTOSIDE; SITOSTEROL; STIGMASTEROL; UNCLASSIFIED DRUG; ANTIOXIDANT; ENZYME INHIBITOR; NEUROPROTECTIVE AGENT;

ANALYTIC METHOD; ANTIOXIDANT ACTIVITY; ARTICLE; BETA CAROTENE BLEACHING TEST; BIOLOGICAL ACTIVITY; BLEACHING; CARDIOSPERMUM HALICACABUM; CHEMICAL COMPOSITION; DEGENERATIVE DISEASE; DPPH RADICAL SCAVENGING ASSAY; ENZYME INHIBITION; ENZYME INHIBITION ASSAY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FOLIN CIOCALTEAU METHOD; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC50; LIPID PEROXIDATION; MASS FRAGMENTOGRAPHY; MELANOGENESIS; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PHYTOCHEMISTRY; PLANT SEED; SAPINDACEAE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; NEURODEGENERATIVE DISEASES; PLANT STRUCTURES; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ANTIOXIDANTS; BUTYRYLCHOLINESTERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; MONOPHENOL MONOOXYGENASE; NEURODEGENERATIVE DISEASES; NEUROPROTECTIVE AGENTS; PLANT COMPONENTS, AERIAL; SAPINDACEAE; SEEDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84907057025     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2013.840614     Document Type: Article

References (37)

1. Neuwinger HD. African traditional medicine: a dictionary of plant use and applications. Stuttgart, Germany: Medpharm GmbH Scientific Publishers; 2000.
2. Venkatesh Babu KC, Krishnakumari S. Cardiospermum halicaca-bum suppresses the production of TNF-alpha and nitric oxide by human peripheral blood mononuclear cells. Afr J Biomed Res 2006; 9:95-9.
3. Pillai NR, Vijayamma N. Some pharmacological studies on Cardiospermum halicacabum Linn. Anc Sci Life 1985;5:32-6.
4. Venkat Rao N, Chandra Prakash K, Shanta Kumar SM. Pharmacological investigation of Cardiospermum halicacabum (Linn) in different animal models of diarrhoea. Indian J Pharm 2006;38:346-9.
5. Kumaran A, Karunakaran RJ. Antioxidant activities of the methanol extract of Cardiospermum halicacabum. Pharm Biol 2006;44: 146-51.
6. Huang MH, Huang SS, Wang BS, et al. Antioxidant and anti-inflammatory properties of Cardiospermum halicacabum and its reference compounds ex vivo and in vivo. J Ethnopharmacol 2011; 133:743-50.
7. Khan MSY, Arya M, Javed K, Khan MH. Chemical examination of Cardiospermum halicacabum. Linn. Indian Drugs 1990;27:257-8.
8. Subramanyam R, Newmaster SG, Paliyath G, Newmaster CB. Exploring ethnobiologucal classifications for novel alternative medicine: a case study of Cardiospermum halicacabum (Modakathon, Balloon Vine) as a traditional herb for treating rheumatoid arthritis. Ethnobotany 2007;19:1-18.
9. Deepan T, Alekhya V, Saravanakumar P, Dhanaraju MD. Phytochemical and anti-microbial studies on the leaves extracts of Cardiospermum halicacabum Linn. Adv Biol Res 2012;6:14-8.
10. Aviram M. Review of human studies on oxidative damage and antioxidant protection related to cardiovascular diseases. Free Rad Res 2000;33:85-97.
11. Christen Y. Oxidative stress and Alzheimer disease. Am J Clin Nutr 2000;71:621S-9S.
12. Rao KSJ, Hegde ML, Anitha S, et al. Amyloid b and neuromelanin-toxic or protective molecules? The cellular context makes the difference. Prog Neurobiol 2006;78:364-73.
13. Tessari I, Bisaglia M, Valle F, et al. The reaction of a-synuclein with tyrosinase: possible implications for Parkinson disease. J Biol Chem 2008;283:16808-17.
14. Zahid M, Saeed M, Yang L, et al. Formation of dopamine quinone-DNA adducts and their potential role in the aetiology of Parkinson's disease. IUBMB Life 2011;63:1087-93.
15. Greggio E, Bergantino E, Carter D, et al. Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease. J Neurochem 2005;93:246-56.
16. Supuran CT. Carbonic anhydrases: novel therapeutic applications for inhibitors and activators. Nat Rev Drug Discov 2008;7:168-81.
17. Ilies M, Banciu MD, Ilies MA, et al. Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties. J Med Chem 2002;45:504-10.
18. Temperini C, Scozzafava A, Supuran CT. Carbonic anhydrase activation and the drug design. Curr Pharm Des 2008;14:708-15.
19. Loizzo MR, Tundis R, Menichini F, Menichini F. Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: an update. Curr Med Chem 2008;15: 1209-28.
20. Loizzo MR, Tundis R, Bonesi M, et al. Radical scavenging, antioxidant and metal chelating activities of Annona cherimola Mill. (cherimoya) peel and pulp in relation to their total phenolic and total flavonoid contents. J Food Comp Anal 2012;25:179-84.
21. Bonesi M, Okusa PN, Tundis R, et al. Chemical composition, antioxidant properties and anti-cholinesterase activity of Cordia gilletii (Boraginaceae) leaves essential oil. Nat Prod Commun 2011; 6:253-7.
22. Tundis R, Bonesi M, Menichini F, et al. Antioxidant and anti-cholinesterase activity of Globularia meridionalis extracts and isolated constituents. Nat Prod Commun 2012;7:1015-20.
23. Tundis R, Loizzo MR, Bonesi M, et al. Comparative study on the antioxidant capacity and cholinesterase inhibitory activity of Citrus aurantifolia Swingle, C. aurantium L., and C. bergamia Risso and Poit. peel essential oils. J Food Sci 2012;77:H40-6.
24. Tundis R, Nadjafi F, Menichini F. Angiotensin-converting enzyme inhibitory activity and antioxidant properties of Nepeta crassifolia Boiss & Buhse and Nepeta binaludensis Jamzad. Phytother Res 2013;27:572-80.
25. Bao K, Dai Y, Zhu Z-B, et al. Design and synthesis of biphenyl derivatives as mushroom tyrosinase inhibitors. Bioorg Med Chem 2010;18:6708-14.
26. Ellman GL, Courtney KD, Andres Jr. V, Feath-Erstone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961;7:88-95.
27. Shen SC, Lee WR, Lin HY, et al. In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. Eur J Pharmacol 2002;446:187-94.
28. Shan BE, Wang MX, Li RQ. Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway. Cancer Invest 2009;27:604-12.
29. Xie T, Wang WP, Mao ZF, et al. Effects of epigallocatechin-3-gallate on pentylenetetrazole-induced kindling, cognitive impairment and oxidative stress in rats. Neurosci Lett 2012;516: 237-41.
30. Jayanthi G, Sathishkumar T, Senthilkumar T, Jegadeesan M. Free radical scavenging potential of Cardiospermum halicacabum L. var. microcarpum (Kunth) Blume seeds. Int Res J Pharm App Sci 2012;2:41-8.
31. Xu Y, Stokes AH, Roskoski Jr R, Vrana KE. Dopamine, in the presence of tyrosinase, covalently modifies and inactivates tyrosine hydroxylase. J Neurosci Res 1998;54:691-7.
32. Xie LP, Chen QX, Huang H, et al. Inhibitory effects of some flavonoids on the activity of mushroom tyrosinase. Biochemistry (Mosc) 2003;68:487-91.
33. Choi MY, Song HS, Hur HS, Sim SS. Whitening activity of luteolin related to the inhibition of cAMP pathway in alpha-MSH-stimulated B16 melanoma cells. Arch Pharm Res 2008;31:1166-71.
34. An SM, Kim HJ, Kim JE, Boo YC. Flavonoids, taxifolin and luteolin attenuate cellular melanogenesis despite increasing tyrosinase protein levels. Phytother Res 2008;22:1200-7.
35. Huh S, Kim YS, Jung E, et al. Melanogenesis inhibitory effect of fatty acid alkyl esters isolated from Oxalis triangularis. Biol Pharm Bull 2010;33:1242-5.
36. Ando H, Ryu A, Hashimoto A, et al. Linoleic acid and alpha-linolenic acid lightens ultraviolet-induced hyperpigmentation of the skin. Arch Dermatol Res 1998;290:375-81.
37. Ren Y, Houghton P, Hider RC. Relevant activities of extracts and constituents of animals used in traditional Chinese medicine for central nervous system effects associated with Alzheimer's disease. J Pharm Pharmacol 2006;58:989-96.