Whitening activity of luteolin related to the inhibition of cAMP pathway in α-MSH-stimulated B16 melanoma cells

Archives of Pharmacal Research

Volumn 31, Issue 9, 2008, Pages 1166-1171

  Choi, Mi Young ^a   Song, Ho Sun ^a   Hur, Hyun Sook ^a   Sim, Sang Soo ^a  

^a Chung Ang University   (South Korea)

Author keywords

Anti oxidant; cAMP; Luteolin; Melanin; Tyrosinase

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ALPHA INTERMEDIN; ARBUTIN; CYCLIC AMP; FORSKOLIN; LUTEOLIN; MELANIN; MONOPHENOL MONOOXYGENASE; PICRIC ACID; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; XANTHINE OXIDASE;

ARTICLE; BIOSYNTHESIS; CELL SURVIVAL; DRUG ANTAGONISM; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MELANOMA; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ALPHA-MSH; ARBUTIN; CELL SURVIVAL; CYCLIC AMP; ENZYME-LINKED IMMUNOSORBENT ASSAY; FORSKOLIN; FREE RADICAL SCAVENGERS; HUMANS; LUTEOLIN; MELANINS; MELANOMA, EXPERIMENTAL; MONOPHENOL MONOOXYGENASE; PICRATES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDES; XANTHINE OXIDASE;

EID: 52649139977     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-001-1284-4     Document Type: Article

References (24)

1. P. P. Agin J. C. Dowdy M. E. Costlow 1991 Diacylglycerol-induced melanogenesis in Skh-2 pigmented hairless mice Photodermatol Photoimmunol Photomed. 8 51 56
2. A. Boland D. Delapierre D. Mossay P. Hans A. Dresse 2000 Propofol protects cultured brain cells from iron ion-induced death: comparison with trolox Eur. J. Pharmacol. 404 21 27
3. P. Cos P. Rajan I. Vedernikova M. Calomme L. Pieters A. J. Vlietinck K. Augustyns A. Haemers D. V. Berghe 2002 In vitro antioxidant profile of phenolic acid derivatives Free Radic. Res. 36 711 716
4. P. Donsing N. Limpeanchob J. Viyoch 2008 Evaluation of the effect of Thai breadfruit's heartwood extract on melanogenesis-inhibitory and antioxidation activities J. Cosmet. Sci. 59 41 58
5. P. S. Friedmann B. A. Gilchrest 1987 Ultraviolet radiation directly induces pigment production by cultured human melanocytes J. Cell. Physiol. 133 88 94
6. P. S. Friedmann F. E. Wren J. N. Matthews 1990 Ultraviolet stimulated melanogenesis by human melanocytes is augmented by di-acyl glycerol but not TPA J. Cell. Physiol. 142 334 341
7. P. R. Gordon C. P. Mansur B. A. Gilchrest 1989 Regulation of human melanocyte growth, dendricity, and melanization by keratinocyte derived factors J. Invest. Dermatol. 92 565 572
8. C. E. Griffiths L. J. Finkel C. M. Ditre T. A. Hamilton C. N. Ellis J. J. Voorhees 1993 Topical tretinoin (retinoic acid) improves melasma. A vehicle-controlled, clinical trial Br. J. Dermatol. 129 415 421
9. G. K. Harris Y. Qian S. S. Leonard D. C. Sbarra X. Shi 2006 Luteolin and chrysin differentially inhibit cyclooxygenase-2 expression and scavenge reactive oxygen species but similarly inhibit prostaglandin-E2 Formation in RAW 264.7 Cells J. Nutr. 136 1517 1521
10. S. Hougee A. Sanders J. Faber Y. M. F. Graus W. B. van den Berg J. Garssen H. F. Smit M. A. Hoijer 2005 Decreased pro-inflammatory cytokine production by LPS-stimulated PBMC upon in vitro incubation with the flavonoids apigenin, luteolin or chrysin, due to selective elimination of monocytes/macrophages Biochem. Pharmacol. 69 241 248
11. G. Hunt C. Todd J. E. Cresswell A. J. Thody 1994 Alphamelanocyte stimulating hormone and its analogue Nle4-DPhe7 alpha-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes J. Cell. Sci. 107 205 211
12. W. Ju X. Wang H. Shi W. Chen S. A. Belinsky Y. Lin 2007 A Critical Role of Luteolin-Induced Reactive Oxygen Species in Blockage of Tumor Necrosis Factor-Activated Nuclear Factor-kB Pathway and Sensitization of Apoptosis in Lung Cancer Cells Mol. Pharmacol. 71 1381 1388
13. K. A. Kim Y. H. Kim M. S. Seo W. K. Lee S. W. Kim H. T. Kim K. H. Lee I. C. Shin J. S. Han H. J. Kim Y. Lim 2002 Mechanism of silica-induced ROS generation in Rat2 fibroblast cells Toxicol. Lett. 135 185 191
14. Y. J. Kim 2007 Antimelanogenic and antioxidant properties of gallic acid Biol. Pharm. Bull. 30 1052 1055
15. K. Maeda M. Fukuda 1996 Arbutin: mechanism of its depigmenting action in human melanocyte culture J. Pharmacol. Exp. Ther. 276 765 769
16. Y. Mishima S. Hatta Y. Ohyama M. Inazu 1988 Induction of melanogenesis suppression: cellular pharmacology and mode of differential action Pigment Cell Res. 1 367 374
17. M. T. T. Nguyen S. Awale Y. Tezuka Q. L. Tran H. Watanabe S. Kadota 2004 Xanthine Oxidase Inhibitory Activity of Vietnamese Medicinal Plants Biol. Pharm. Bull. 27 1414 1421
18. A. Nagao M. Seki H. Kobayashi 1999 Inhibition of Xanthine Oxidase by Flavonoids Biosci. Biotechnol. Biochem. 63 1787 1790
19. C. Pinto D. Papa M. Hubner T. C. Mou G. H. Lushington R. Seifert 2008 Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs J. Pharmacol. Exp. Ther. 325 27 36
20. R. Shi Q. Huang X. Zhu Y. B. Ong B. Zhao J. Lu C. N. Ong H. M. Shen 2007 Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase-mediated p53 phosphorylation and stabilization Mol. Cancer Ther. 6 1338
21. P. K. Smith R. I. Krohn G. T. Hermanson A. K. Mallia F. H. Gartner M. D. Provenzano E. K. Fujimoto N. M. Goeke B. J. Olson D. C. Klenk 1985 Measurement of protein using bicinchoninic acid Anal. Biochem. 150 76 85
22. H. J. Woerdenbag I. Merfort C. M. Passreiter T. J. Schmidt G. Willuhn W. van Uden N. Pras H. H. Kampinga A. W. Konings 1994 Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines Planta Med. 60 434 437
23. G. Wong J. Pawelek 1975 Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in Cloudman S91 melanoma cells Nature. 255 644 646
24. L. Ziyan Z. Yongmei Z. Nan T. Ning L. Baolin 2007 Evaluation of the anti-inflammatory activity of luteolin in experimental animal models Planta Med. 73 221 226