Sulfonamides incorporating fluorine and 1,3,5-triazine moieties are effective inhibitors of three β-class carbonic anhydrases from Mycobacterium tuberculosis

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 29, Issue 5, 2014, Pages 686-689

  Ceruso, Mariangela ^a   Vullo, Daniela ^a   Scozzafava, Andrea ^a   Supuran, Claudiu T ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

1 3 5 triazine; Carbonic anhydrase; Fluoride; Mycobacterium tuberculosis; Sulfonamide; Carbonic anhydrases

Indexed keywords

BACTERIAL ENZYME; CARBONATE DEHYDRATASE INHIBITOR; FLUORINE DERIVATIVE; MYCOBACTERIUM TUBERCULOSIS CARBONIC ANHYDRASE 1; MYCOBACTERIUM TUBERCULOSIS CARBONIC ANHYDRASE 2; MYCOBACTERIUM TUBERCULOSIS CARBONIC ANHYDRASE 3; SULFONAMIDE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; CARBONATE DEHYDRATASE; FLUORINE;

ARTICLE; ENZYME INHIBITION; INHIBITION CONSTANT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; METABOLISM; SYNTHESIS;

BIOCATALYSIS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORINE; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TRIAZINES;

EID: 84907056586     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2013.842233     Document Type: Article

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