메뉴 건너뛰기




Volumn 5, Issue 4, 2014, Pages 409-419

Effect of intestinal colonisation by two Lactobacillus strains on the immune response of gnotobiotic mice

Author keywords

Germ free mice; Gut; Immunomodulation; Lactobacillus; Probiotics

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 5; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

EID: 84907023332     PISSN: 18762883     EISSN: 18762891     Source Type: Journal    
DOI: 10.3920/BM2013.0075     Document Type: Article
Times cited : (14)

References (70)
  • 1
    • 0029440778 scopus 로고
    • Effect of administration of bifidobacteria and lactic acid bacteria to newborn calves and piglets
    • Abe, F., Ishibashi, N. and Ssimamura, S., 1995. Effect of administration of bifidobacteria and lactic acid bacteria to newborn calves and piglets. Journal of Dairy Science 78: 2838-2846.
    • (1995) Journal of Dairy Science , vol.78 , pp. 2838-2846
    • Abe, F.1    Ishibashi, N.2    Ssimamura, S.3
  • 3
    • 84907031125 scopus 로고    scopus 로고
    • Perfil de hidrofobicidade da superfi´cie celular de Bifidobacterium lactis Bb12 e Bifidobacterium longum Bb46 em func¸ão do meio de cultura
    • Barbosa, F.H.F., Silva, A.M., Martins, F.S. and Nicoli, J.R., 2005. Perfil de hidrofobicidade da superfi´cie celular de Bifidobacterium lactis Bb12 e Bifidobacterium longum Bb46 em func¸ão do meio de cultura. Revista de Biologia e Cieˆncias da Terra 5: 1-11.
    • (2005) Revista de Biologia e Cieˆncias da Terra , vol.5 , pp. 1-11
    • Barbosa, F.H.F.1    Silva, A.M.2    Martins, F.S.3    Nicoli, J.R.4
  • 4
    • 0027440890 scopus 로고
    • Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions
    • Bernet, M.F., Brassart, D., Neeser, J.R. and Servin, A.L., 1993. Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions. Applied and Environmental Microbiology 59: 4121-4128.
    • (1993) Applied and Environmental Microbiology , vol.59 , pp. 4121-4128
    • Bernet, M.F.1    Brassart, D.2    Neeser, J.R.3    Servin, A.L.4
  • 5
    • 83855165652 scopus 로고    scopus 로고
    • Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa
    • Bron, P.A., Van Baarlen, P. and Kleerebezem, M., 2012. Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa. Nature Reviews Microbiology 10: 66-78.
    • (2012) Nature Reviews Microbiology , vol.10 , pp. 66-78
    • Bron, P.A.1    Van Baarlen, P.2    Kleerebezem, M.3
  • 6
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P. and Sacchi, N., 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 162: 156-159.
    • (1987) Analytical Biochemistry , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 7
    • 85181634226 scopus 로고    scopus 로고
    • BioPlus 2B
    • Available at
    • Chr. Hansen A/S, 2012. BioPlus 2B. Available at: http://www.chrhansen. com.
    • (2012)
    • Hansen, A.S.1
  • 8
    • 0024410891 scopus 로고
    • Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice
    • Coffman, R.L., Seymour, B.W., Hudak, S., Jackson, J. and Rennick, D., 1989. Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice. Science 245: 308-310.
    • (1989) Science , vol.245 , pp. 308-310
    • Coffman, R.L.1    Seymour, B.W.2    Hudak, S.3    Jackson, J.4    Rennick, D.5
  • 9
    • 85181645045 scopus 로고    scopus 로고
    • Legislac¸ão e E´tica
    • Available at
    • Cole´gio Brasileiro de Experimentac¸ão Animal (COBEA), 2009. Legislac¸ão e E´tica. Available at: http://www.cobea.org.br.
    • (2009)
  • 10
    • 0037073572 scopus 로고    scopus 로고
    • Microbes versus microbes: immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens
    • Cross, M.L., 2002. Microbes versus microbes: immune signals generated by probiotic lactobacilli and their role in protection against microbial pathogens. FEMS Immunology and Medical Microbiology 34: 245-253.
    • (2002) FEMS Immunology and Medical Microbiology , vol.34 , pp. 245-253
    • Cross, M.L.1
  • 13
    • 18944406651 scopus 로고    scopus 로고
    • Antibiotic growth promoters in agriculture: history and mode of action
    • Dibner, J.J. and Richards, J.D., 2005. Antibiotic growth promoters in agriculture: history and mode of action. Poultry Science 84: 634-643.
    • (2005) Poultry Science , vol.84 , pp. 634-643
    • Dibner, J.J.1    Richards, J.D.2
  • 15
    • 55149090692 scopus 로고    scopus 로고
    • Th17 cytokines and mucosal immunity
    • Dubin, P.J. and Kolls, J.K., 2008. Th17 cytokines and mucosal immunity. Review of Immunology 226: 160-171.
    • (2008) Review of Immunology , vol.226 , pp. 160-171
    • Dubin, P.J.1    Kolls, J.K.2
  • 17
    • 12844283422 scopus 로고    scopus 로고
    • Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition
    • European Commission (EC), 2012. Regulation (EC) No 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition. Official Journal of the European Union L 268: 29-43.
    • (2012) Official Journal of the European Union L , vol.268 , pp. 29-43
  • 18
    • 81155149967 scopus 로고    scopus 로고
    • Control of host inflammatory responsiveness by indigenous microbiota reveals an adaptive component of the innate immune system
    • Fagundes, C.T., Souza, D.G., Nicoli, J.R. and Teixeira, M.M., 2011. Control of host inflammatory responsiveness by indigenous microbiota reveals an adaptive component of the innate immune system. Microbes and Infection 13: 1121-1132.
    • (2011) Microbes and Infection , vol.13 , pp. 1121-1132
    • Fagundes, C.T.1    Souza, D.G.2    Nicoli, J.R.3    Teixeira, M.M.4
  • 19
    • 61849094549 scopus 로고    scopus 로고
    • Report of a Joint FAO/ WHO expert consultation on guidelines for the evaluation of probiotics in food
    • FAO/WHO, Rome, Italy
    • Food and Agricultural Organization of the United Nations (FAO)/ World Health Organization (WHO), 2002. Report of a Joint FAO/ WHO expert consultation on guidelines for the evaluation of probiotics in food. FAO/WHO, Rome, Italy.
    • (2002)
  • 20
    • 84894148123 scopus 로고    scopus 로고
    • Draft Guidance for Industry 213, new animal drugs and new animal drug combination products administered in or on medicated feed or drinking water of food-producing animals: recommendations for drug sponsors for voluntarily aligning product use conditions with GFI 209
    • FDA, Silver Spring, MD, USA
    • Food and Drug Administration (FDA), 2012a. Draft Guidance for Industry #213, new animal drugs and new animal drug combination products administered in or on medicated feed or drinking water of food-producing animals: recommendations for drug sponsors for voluntarily aligning product use conditions with GFI #209. FDA, Silver Spring, MD, USA.
    • (2012)
  • 21
    • 78649640629 scopus 로고    scopus 로고
    • Guidance for Industry 209, the judicious use of medically important antimicrobial drugs in food-producing animals
    • FDA, Silver Spring, MD, USA
    • Food and Drug Administration (FDA), 2012b. Guidance for Industry #209, the judicious use of medically important antimicrobial drugs in food-producing animals. FDA, Silver Spring, MD, USA.
    • (2012)
  • 22
    • 0004055257 scopus 로고
    • Probiotics: the scientific basis
    • Chapman and Hall, London, UK
    • Fuller, R., 1992. Probiotics: the scientific basis. Chapman and Hall, London, UK.
    • (1992)
    • Fuller, R.1
  • 23
    • 77955287672 scopus 로고    scopus 로고
    • Probiotics and prebiotics in animal feeding for safe food production
    • Gaggi`a, F., Mattarelli, P. and Biavati, B., 2010. Probiotics and prebiotics in animal feeding for safe food production. International Journal of Food Microbiology 141 Suppl. 1: S15-S28.
    • (2010) International Journal of Food Microbiology , vol.141 , pp. S15-S28
    • F.1    Gaggi2    Mattarelli, P.4    Biavati, B.5
  • 25
    • 77953618012 scopus 로고    scopus 로고
    • Probiotic attributes of Lactobacillus strains isolate from food and of human origin
    • Gaudana, S.B., Dhanani, A.S. and Bagchi, T., 2010. Probiotic attributes of Lactobacillus strains isolate from food and of human origin. British Journal of Nutrition 103: 1620-1628.
    • (2010) British Journal of Nutrition , vol.103 , pp. 1620-1628
    • Gaudana, S.B.1    Dhanani, A.S.2    Bagchi, T.3
  • 26
    • 0035710229 scopus 로고    scopus 로고
    • An overview of real-time quantitative PCR: applications to quantify cytokine gene expression
    • Giulietti, A., Overbergh, L., Valckx, D., Decallonne, B., Bouillon, R. and Mathieu, C., 2001. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25: 386-401.
    • (2001) Methods , vol.25 , pp. 386-401
    • Giulietti, A.1    Overbergh, L.2    Valckx, D.3    Decallonne, B.4    Bouillon, R.5    Mathieu, C.6
  • 28
    • 45449087921 scopus 로고    scopus 로고
    • qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
    • Hellemans, J., Mortier, G., Paepe, A.D., Speleman, F. and Vandesompele, J., 2007. qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data. Genome Biology 8: R19.
    • (2007) Genome Biology , vol.8 , pp. R19
    • Hellemans, J.1    Mortier, G.2    Paepe, A.D.3    Speleman, F.4    Vandesompele, J.5
  • 31
    • 36048970363 scopus 로고    scopus 로고
    • Use of 'natural' products as alternatives to antibiotic feed additives in ruminant production
    • Jouany, J.P. and Morgavi, D.P., 2007. Use of 'natural' products as alternatives to antibiotic feed additives in ruminant production. Animal 1: 1443-1466.
    • (2007) Animal , vol.1 , pp. 1443-1466
    • Jouany, J.P.1    Morgavi, D.P.2
  • 32
    • 0035982432 scopus 로고    scopus 로고
    • Performance of male crossbred calves as influenced by substitution of grain by wheat bran and the addition of lactic acid bacteria to diet
    • Khuntia, A. and Chaudhary, L.C., 2002. Performance of male crossbred calves as influenced by substitution of grain by wheat bran and the addition of lactic acid bacteria to diet. Australasian Journal of Animal Sciences 15: 188-194.
    • (2002) Australasian Journal of Animal Sciences , vol.15 , pp. 188-194
    • Khuntia, A.1    Chaudhary, L.C.2
  • 35
    • 78650647326 scopus 로고    scopus 로고
    • Has the microbiota played a critical role in the evolution of the adaptive immune system
    • Lee, Y.K. and Mazmanian, S.K., 2010. Has the microbiota played a critical role in the evolution of the adaptive immune system? Science 330: 1768-1773.
    • (2010) Science , vol.330 , pp. 1768-1773
    • Lee, Y.K.1    Mazmanian, S.K.2
  • 36
    • 33646175590 scopus 로고    scopus 로고
    • Intestinal and pulmonary mucosal T cells: local heroes fight to maintain the status quo
    • Lefrancois, L. and Puddington, L., 2006. Intestinal and pulmonary mucosal T cells: local heroes fight to maintain the status quo. Annual Review of Immunology 24: 681-704.
    • (2006) Annual Review of Immunology , vol.24 , pp. 681-704
    • Lefrancois, L.1    Puddington, L.2
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
    • Livak, K.J. and Schmittgen, T.D., 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 39
    • 0031158713 scopus 로고    scopus 로고
    • Survival of lactic acid bacteria in a dynamic model of the stomach and small intestine: validation and effects of bile
    • Marteau, P., Minekus, M., Havenaar, R. and Huis in't Veld, J., 1997a. Survival of lactic acid bacteria in a dynamic model of the stomach and small intestine: validation and effects of bile. Journal of Dairy Science 80: 1031-1037.
    • (1997) Journal of Dairy Science , vol.80 , pp. 1031-1037
    • Marteau, P.1    Minekus, M.2    Havenaar, R.3    Huis In't Veld, J.4
  • 40
    • 0031009529 scopus 로고    scopus 로고
    • Effect of intrajejunal perfusion and chronic ingestion of Lactobacillus johnsonii strain La1 on serum concentrations and jejunal secretions of immunoglobulins and serum proteins in healthy humans
    • Marteau, P., Vaerman, J.P., Dehennin, J.P., Bord, S., Brassart, D., Pochart, P., Desjeux, J.F. and Rambaud, J.C., 1997b. Effect of intrajejunal perfusion and chronic ingestion of Lactobacillus johnsonii strain La1 on serum concentrations and jejunal secretions of immunoglobulins and serum proteins in healthy humans. Gastroente´rologie Clinique et Biologique 21: 293-298.
    • (1997) Gastroente´rologie Clinique et Biologique , vol.21 , pp. 293-298
    • Marteau, P.1    Vaerman, J.P.2    Dehennin, J.P.3    Bord, S.4    Brassart, D.5    Pochart, P.6    Desjeux, J.F.7    Rambaud, J.C.8
  • 41
    • 84907023931 scopus 로고    scopus 로고
    • Modelos animais gnotobio´ticos e convencionais para a selec¸ão e avaliac¸ão de probio´ticos
    • In: Ferreira, C.L.L.F. (ed.) Prebio´ticos e probio´ticos: atualizac¸ão e prospecc¸ão. Rubio, Vic¸osa, MG, Brazil
    • Martins, F.S., Generoso, S.V., Rodrigues, A.C.P., Silva, A.M., Neumann, E., Lima-Filho, J.V.M., Bambirra, E.A., Arantes, R.M.E., Carmona, D.C., Cardoso, V.N., Vieira, L.Q. and Nicoli, J.R., 2012. Modelos animais gnotobio´ticos e convencionais para a selec¸ão e avaliac¸ão de probio´ticos. In: Ferreira, C.L.L.F. (ed.) Prebio´ticos e probio´ticos: atualizac¸ão e prospecc¸ão. Rubio, Vic¸osa, MG, Brazil.
    • (2012)
    • Martins, F.S.1    Generoso, S.V.2    Rodrigues, A.C.P.3    Silva, A.M.4    Neumann, E.5    Lima-Filho, J.V.M.6    Bambirra, E.A.7    Arantes, R.M.E.8    Carmona, D.C.9    Cardoso, V.N.10    Vieira, L.Q.11    Nicoli, J.R.12
  • 42
    • 69449102096 scopus 로고    scopus 로고
    • Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties
    • Martins, F.S., Silva, A.A., Vieira, A.T., Barbosa, F.H.F., Arantes, R.M.E., Teixeira, M.M. and Nicoli, J.R., 2009. Comparative study of Bifidobacterium animalis, Escherichia coli, Lactobacillus casei and Saccharomyces boulardii probiotic properties. Archives of Microbiology 191: 623-630.
    • (2009) Archives of Microbiology , vol.191 , pp. 623-630
    • Martins, F.S.1    Silva, A.A.2    Vieira, A.T.3    Barbosa, F.H.F.4    Arantes, R.M.E.5    Teixeira, M.M.6    Nicoli, J.R.7
  • 44
    • 53049101551 scopus 로고    scopus 로고
    • Aditivos alternativos na produc¸ão de aves: probio´ticos e prebio´ticos
    • In: Anais da 38° Reunião Anual da Sociedade Brasileira de Zootecnia. Sociedade de Zoolo´gicos e Aqua´rios do Brazil, Piracicaba, SP, Brazil
    • Mentem, J.F.M., 2001. Aditivos alternativos na produc¸ão de aves: probio´ticos e prebio´ticos. In: Anais da 38° Reunião Anual da Sociedade Brasileira de Zootecnia. Sociedade de Zoolo´gicos e Aqua´rios do Brazil, Piracicaba, SP, Brazil, pp. 141-157.
    • (2001) , pp. 141-157
    • Mentem, J.F.M.1
  • 45
    • 77955491496 scopus 로고    scopus 로고
    • IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection
    • Miyazaki, Y., Hamano, S., Wang, S., Shimanoe, Y., Iwakura, Y. and Yoshida, H., 2010. IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection. Journal of Immunology 185: 1150-1157.
    • (2010) Journal of Immunology , vol.185 , pp. 1150-1157
    • Miyazaki, Y.1    Hamano, S.2    Wang, S.3    Shimanoe, Y.4    Iwakura, Y.5    Yoshida, H.6
  • 46
    • 0018092512 scopus 로고
    • Increase in the population of duodenal immunoglobulin A plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin
    • Moreau, M.C., Ducluzeau, R., Guy-Grand, D. and Muller, M.C., 1978. Increase in the population of duodenal immunoglobulin A plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin. Infection and Immunity 21: 532-539.
    • (1978) Infection and Immunity , vol.21 , pp. 532-539
    • Moreau, M.C.1    Ducluzeau, R.2    Guy-Grand, D.3    Muller, M.C.4
  • 47
    • 0025733855 scopus 로고
    • The role of IL-10 in crossregulation of Th1 and Th2 responses
    • Mosmann, T.R. and Moore, K.W., 1991. The role of IL-10 in crossregulation of Th1 and Th2 responses. Immunology Today 12: A49-A53.
    • (1991) Immunology Today , vol.12 , pp. A49-A53
    • Mosmann, T.R.1    Moore, K.W.2
  • 48
    • 84860863242 scopus 로고    scopus 로고
    • Biotechnology of lactic acid bacteria: novel applications
    • Wiley-Blackwell Publishing, Chichester, UK
    • Mozzi, F., Raya, R.R and Vignolo, G.M., 2010. Biotechnology of lactic acid bacteria: novel applications. Wiley-Blackwell Publishing, Chichester, UK.
    • (2010)
    • Mozzi, F.1    Raya, R.R.2    Vignolo, G.M.3
  • 51
    • 33646695914 scopus 로고    scopus 로고
    • Probiotics and their fermented food products are beneficial for health
    • Parvez, S., Malik, K.A., Ah Kang, S. and Kim, H.Y., 2006. Probiotics and their fermented food products are beneficial for health. Journal of Applied Microbiology 100: 1171-1185.
    • (2006) Journal of Applied Microbiology , vol.100 , pp. 1171-1185
    • Parvez, S.1    Malik, K.A.2    Ah Kang, S.3    Kim, H.Y.4
  • 52
    • 0029337230 scopus 로고
    • Symposium: probiotic bacteria for humans: clinical systems for evaluation of effectiveness - immune system stimulation by probiotics
    • Perdigo´n, G., Alvarez, S., Rachid, M., Agu¨ero, G. and Gobbato, N., 1995. Symposium: probiotic bacteria for humans: clinical systems for evaluation of effectiveness - immune system stimulation by probiotics. Journal of Dairy Science 78: 1597-1606.
    • (1995) Journal of Dairy Science , vol.78 , pp. 1597-1606
    • Perdigo´n, G.1    Alvarez, S.2    Rachid, M.3    Agu¨ero, G.4    Gobbato, N.5
  • 53
    • 33847191741 scopus 로고    scopus 로고
    • Effect of Lactobacillus acidophilus strain NP51 on Escherichia coli O157:H7 fecal shedding and finishing performance in beef feedlot cattle
    • Peterson, R.E., Klopfenstein, T.J., Erickson, G.E., Folmer, J., Hinkley, S., Moxley, R.A. and Smith, D.R., 2007. Effect of Lactobacillus acidophilus strain NP51 on Escherichia coli O157:H7 fecal shedding and finishing performance in beef feedlot cattle. Journal of Food Protection 70: 287-291.
    • (2007) Journal of Food Protection , vol.70 , pp. 287-291
    • Peterson, R.E.1    Klopfenstein, T.J.2    Erickson, G.E.3    Folmer, J.4    Hinkley, S.5    Moxley, R.A.6    Smith, D.R.7
  • 55
    • 0003505406 scopus 로고
    • Handbook of laboratory animal science
    • Gnotobiotics. In: Melby Jr., E. C. and Altmann, N. H. (eds.) CRC press, Cleveland, OH, USA
    • Pleasants, J.R., 1974. Gnotobiotics. In: Melby Jr., E.C. and Altmann, N.H. (eds.) Handbook of laboratory animal science. CRC press, Cleveland, OH, USA, pp. 119-174.
    • (1974) , pp. 119-174
    • Pleasants, J.R.1
  • 56
    • 58149314577 scopus 로고    scopus 로고
    • IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa
    • Priebe, G.P., Walsh, R.L., Cederroth, T.A., Kamei, A., Coutinho-Sledge, Y.S., Goldberg, J.B., and Pier, G.B., 2008. IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa. Journal of Immunology 181: 4965-4975.
    • (2008) Journal of Immunology , vol.181 , pp. 4965-4975
    • Priebe, G.P.1    Walsh, R.L.2    Cederroth, T.A.3    Kamei, A.4    Coutinho-Sledge, Y.S.5    Goldberg, J.B.6    Pier, G.B.7
  • 57
    • 33645470529 scopus 로고    scopus 로고
    • Comparison of bacterial flora and enzymatic activity in faeces of infants and calves
    • Rada, V., Vlkova, E., Nevoral, J. and Trojanova, I., 2006. Comparison of bacterial flora and enzymatic activity in faeces of infants and calves. FEMS Microbiology Letters 258: 25-28.
    • (2006) FEMS Microbiology Letters , vol.258 , pp. 25-28
    • Rada, V.1    Vlkova, E.2    Nevoral, J.3    Trojanova, I.4
  • 59
    • 0025963798 scopus 로고
    • Short chain fatty acids in the terminal ileum accelerate stomach to caecum transit time in the rat
    • Richardson, A., Delbridge, A.T., Brown, N.J., Rumsey, R.D.E. and Read, N.W., 1991. Short chain fatty acids in the terminal ileum accelerate stomach to caecum transit time in the rat. Gut 32: 266-269.
    • (1991) Gut , vol.32 , pp. 266-269
    • Richardson, A.1    Delbridge, A.T.2    Brown, N.J.3    Rumsey, R.D.E.4    Read, N.W.5
  • 60
    • 0027215897 scopus 로고
    • CTLA-8, cloned from an activated T cell, bearing AUrich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene
    • Rouvier, E., Luciani, M.F., Matte´i, M.G., Denizot, F. and Golstein, P., 1993. CTLA-8, cloned from an activated T cell, bearing AUrich messenger RNA instability sequences, and homologous to a herpesvirus saimiri gene. Journal of Immunology 150: 5445-5456.
    • (1993) Journal of Immunology , vol.150 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.F.2    Matte´i, M.G.3    Denizot, F.4    Golstein, P.5
  • 63
    • 0032416591 scopus 로고    scopus 로고
    • The effect of consumption of milk fermented by Lactobacillus casei strain Shirota on the intestinal microflora and immune parameters in humans
    • Spanhaak, S., Havenaar, R. and Schaafsma, G., 1998. The effect of consumption of milk fermented by Lactobacillus casei strain Shirota on the intestinal microflora and immune parameters in humans. European Journal of Clinical Nutrition 52: 899-907.
    • (1998) European Journal of Clinical Nutrition , vol.52 , pp. 899-907
    • Spanhaak, S.1    Havenaar, R.2    Schaafsma, G.3
  • 64
    • 0032075972 scopus 로고    scopus 로고
    • Studies of the intestinal microflora: a prerequisite for the development of probiotics
    • Tannock, G.W., 1998. Studies of the intestinal microflora: a prerequisite for the development of probiotics. International Dairy Journal 8: 527-533.
    • (1998) International Dairy Journal , vol.8 , pp. 527-533
    • Tannock, G.W.1
  • 67
    • 10744228973 scopus 로고    scopus 로고
    • Lactic acid starter and probiotic bacteria: a comparative in vitro study of probiotic characteristics and biological barriers resistance
    • Vinderola, C.G. and Reinheimer, J.A., 2003. Lactic acid starter and probiotic bacteria: a comparative in vitro study of probiotic characteristics and biological barriers resistance. Food Research International 36: 895-904.
    • (2003) Food Research International , vol.36 , pp. 895-904
    • Vinderola, C.G.1    Reinheimer, J.A.2
  • 70
    • 37549072218 scopus 로고    scopus 로고
    • Lactobacillus fermentum ACA-DC 179 displays probiotic potential in vitro and protects against trinitrobenzene sulfonic acid (TNBS)-induced colitis and Salmonella infection in murine models
    • Zoumpopoulou, G., Foligne, B., Christodou, L.K., Grangette, C., Pot, B. and Tsakalidou, E., 2008. Lactobacillus fermentum ACA-DC 179 displays probiotic potential in vitro and protects against trinitrobenzene sulfonic acid (TNBS)-induced colitis and Salmonella infection in murine models. International Journal of Food Microbiology 121: 18-26.
    • (2008) International Journal of Food Microbiology , vol.121 , pp. 18-26
    • Zoumpopoulou, G.1    Foligne, B.2    Christodou, L.K.3    Grangette, C.4    Pot, B.5    Tsakalidou, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.