Inhibition of Borna disease virus replication by an endogenous bornavirus-like element in the ground squirrel genome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 36, 2014, Pages 13175-13180

  Fujino, Kan ^a,c   Horie, Masayuki ^a,d   Honda, Tomoyuki ^a   Merriman, Dana K ^a   Tomonaga, Keizo ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF WISCONSIN OSHKOSH   (United States)

^c AZABU UNIVERSITY   (Japan)

^d KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Antiviral immunity; Endogenous nonretroviral viruses

Indexed keywords

DNA DIRECTED DNA POLYMERASE; RIBONUCLEOPROTEIN; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; BORNA DISEASE; BORNA DISEASE VIRUS; CHEMISTRY; CHLOROCEBUS AETHIOPS; GENETIC TRANSFECTION; GENETICS; GENOME; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REPLICON; SCIURIDAE; TRANSMISSION; VERO CELL LINE; VIROLOGY; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BORNA DISEASE; BORNA DISEASE VIRUS; CERCOPITHECUS AETHIOPS; CONSERVED SEQUENCE; DNA-DIRECTED DNA POLYMERASE; GENOME; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; REPLICON; RIBONUCLEOPROTEINS; SCIURIDAE; TRANSFECTION; VERO CELLS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84906968902     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1407046111     Document Type: Article

References (46)

1. Bock M, Stoye JP (2000) Endogenous retroviruses and the human germline. Curr Opin Genet Dev 10(6):651-655.
2. Bannert N, Kurth R (2004) Retroelements and the human genome: New perspectives on an old relation. Proc Natl Acad Sci USA 101(Suppl 2):14572-14579.
3. Stoye JP (2012) Studies of endogenous retroviruses reveal a continuing evolutionary saga. Nat Rev Microbiol 10(6):395-406.
4. Krieg AM, Gourley MF, Perl A (1992) Endogenous retroviruses: Potential etiologic agents in autoimmunity. FASEB J 6(8):2537-2544.
5. Singh S, Kaye S, Gore ME, McClure MO, Bunker CB (2009) The role of human endogenous retroviruses in melanoma. Br J Dermatol 161(6):1225-1231.
6. Christensen T (2010) HERVs in neuropathogenesis. J Neuroimmune Pharmacol 5(3):326-335.
7. Evans LH, et al. (2006) In vivo interactions of ecotropic and polytropic murine leukemia viruses in mixed retrovirus infections. J Virol 80(10):4748-4757.
8. Roy-Burman P (1995) Endogenous env elements: Partners in generation of pathogenic feline leukemia viruses. Virus Genes 11(2-3):147-161.
9. Mi S, et al. (2000) Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis. Nature 403(6771):785-789.
10. Aswad A, Katzourakis A (2012) Paleovirology and virally derived immunity. Trends Ecol Evol 27(11):627-636.
11. Dupressoir A, et al. (2005) Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae. Proc Natl Acad Sci USA 102(3):725-730.
12. Bernard D, et al. (2005) Identification and characterization of a novel retroviral-like aspartic protease specifically expressed in human epidermis. J Invest Dermatol 125(2):278-287.
13. Matsui T, et al. (2011) SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing. EMBO Mol Med 3(6):320-333.
14. Stoye JP (1998) Fv1, the mouse retrovirus resistance gene. Rev Sci Tech 17(1):269-277.
15. Mura M, et al. (2004) Late viral interference induced by transdominant Gag of an endogenous retrovirus. Proc Natl Acad Sci USA 101(30):11117-11122.
16. Horie M, et al. (2010) Endogenous non-retroviral RNA virus elements in mammalian genomes. Nature 463(7277):84-87.
17. Belyi VA, Levine AJ, Skalka AM (2010) Unexpected inheritance: Multiple integrations of ancient bornavirus and ebolavirus/marburgvirus sequences in vertebrate genomes. PLoS Pathog 6(7):e1001030.
18. Katzourakis A, Gifford RJ (2010) Endogenous viral elements in animal genomes. PLoS Genet 6(11):e1001191.
19. Tomonaga K, Kobayashi T, Ikuta K (2002) Molecular and cellular biology of Borna disease virus infection. Microbes Infect 4(4):491-500.
20. Suzuki Y, Kobayashi Y, Horie M, Tomonaga K, Origin of endogenous bornavirus-like nucleoprotein elements in thirteen-lined ground squirrels. Genes Genet Syst, in press.
21. Matsumoto Y, et al. (2012) Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection. Cell Host Microbe 11(5):492-503.
22. Schneider U, Naegele M, Staeheli P, Schwemmle M (2003) Active borna disease virus polymerase complex requires a distinct nucleoprotein-to-phosphoprotein ratio but no viral X protein. J Virol 77(21):11781-11789.
23. Chase G, et al. (2007) Borna disease virus matrix protein is an integral component of the viral ribonucleoprotein complex that does not interfere with polymerase activity. J Virol 81(2):743-749.
24. Sasaki S, Ludwig H (1993) In borna disease virus infected rabbit neurons 100 nm particle structures accumulate at areas of Joest-Degen inclusion bodies. Zentralbl Veterinarmed B 40(4):291-297.
25. Geib T, et al. (2003) Selective virus resistance conferred by expression of Borna disease virus nucleocapsid components. J Virol 77(7):4283-4290.
26. Yanai H, et al. (2006) Development of a novel Borna disease virus reverse genetics system using RNA polymerase II promoter and SV40 nuclear import signal. Microbes Infect 8(6):1522-1529.
27. Kobayashi T, et al. (1998) Nuclear targeting activity associated with the amino terminal region of the Borna disease virus nucleoprotein. Virology 243(1):188-197.
28. Berg M, Ehrenborg C, Blomberg J, Pipkorn R, Berg AL (1998) Two domains of the Borna disease virus p40 protein are required for interaction with the p23 protein. J Gen Virol 79(Pt 12):2957-2963.
29. Kobayashi T, et al. (2001) Borna disease virus nucleoprotein requires both nuclear localization and export activities for viral nucleocytoplasmic shuttling. J Virol 75(7):3404-3412.
30. Rudolph MG, et al. (2003) Crystal structure of the borna disease virus nucleoprotein. Structure 11(10):1219-1226.
31. Hock M, et al. (2010) RNA induced polymerization of the Borna disease virus nucleoprotein. Virology 397(1):64-72.
32. Schwemmle M, et al. (1998) Interactions of the borna disease virus P, N, and X proteins and their functional implications. J Biol Chem 273(15):9007-9012.
33. Schwemmle M, Jehle C, Shoemaker T, Lipkin WI (1999) Characterization of the major nuclear localization signal of the Borna disease virus phosphoprotein. J Gen Virol 80(Pt 1):97-100.
34. Yanai H, et al. (2006) A methionine-rich domain mediates CRM1-dependent nuclear export activity of Borna disease virus phosphoprotein. J Virol 80(3):1121-1129.
35. Watanabe Y, Ohtaki N, Hayashi Y, Ikuta K, Tomonaga K (2009) Autogenous translational regulation of the Borna disease virus negative control factor X from polycistronic mRNA using host RNA helicases. PLoS Pathog 5(11):e1000654.
36. Best S, Le Tissier P, Towers G, Stoye JP (1996) Positional cloning of the mouse retrovirus restriction gene Fv1. Nature 382(6594):826-829.
37. Hilditch L, et al. (2011) Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1. Proc Natl Acad Sci USA 108(14):5771-5776.
38. Arnaud F, Varela M, Spencer TE, Palmarini M (2008) Coevolution of endogenous betaretroviruses of sheep and their host. Cell Mol Life Sci 65(21):3422-3432.
39. Spencer TE, Mura M, Gray CA, Griebel PJ, Palmarini M (2003) Receptor usage and fetal expression of ovine endogenous betaretroviruses: Implications for coevolution of endogenous and exogenous retroviruses. J Virol 77(1):749-753.
40. Arnaud F, Murcia PR, Palmarini M (2007) Mechanisms of late restriction induced by an endogenous retrovirus. J Virol 81(20):11441-11451.
41. Monde K, Contreras-Galindo R, Kaplan MH, Markovitz DM, Ono A (2012) Human endogenous retrovirus K Gag coassembles with HIV-1 Gag and reduces the release efficiency and infectivity of HIV-1. J Virol 86(20):11194-11208.
42. Bieniasz PD (2004) Intrinsic immunity: A front-line defense against viral attack. Nat Immunol 5(11):1109-1115.
43. Dupressoir A, Lavialle C, Heidmann T (2012) From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation. Placenta 33(9):663-671.
44. Ewing RM, et al. (2007) Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol 3:89.
45. Lando M, et al. (2013) Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling. J Pathol 230(1):59-69.
46. Daito T, et al. (2011) A novel borna disease virus vector system that stably expresses foreign proteins from an intercistronic noncoding region. J Virol 85(23):12170-12178.