A novel borna disease virus vector system that stably expresses foreign proteins from an intercistronic noncoding region

Journal of Virology

Volumn 85, Issue 23, 2011, Pages 12170-12178

  Daito, Takuji ^a,b   Fujino, Kan ^a,b   Honda, Tomoyuki ^b,d   Matsumoto, Yusuke ^a,b   Watanabe, Yohei ^b   Tomonaga, Keizo ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c The University of Tokyo ^*

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BORNA DISEASE VIRUS VECTOR; GREEN FLUORESCENT PROTEIN; MATRIX PROTEIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS PHOSPHOPROTEIN; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BORNA DISEASE; BORNA DISEASE VIRUS; BRAIN; CELL CULTURE; CONTROLLED STUDY; GENE CASSETTE; GENE INSERTION; GENE SEQUENCE; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; INTERCISTRONIC NONCODING REGION; INTRON; L GENE; M GENE; MOUSE; NONHUMAN; P GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STABLE EXPRESSION; UNTRANSLATED REGION; VIRION; VIRUS GENE; VIRUS PARTICLE;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; BORNA DISEASE VIRUS; BRAIN; BRAIN NEOPLASMS; CERCOPITHECUS AETHIOPS; DNA, INTERGENIC; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; GENETIC VECTORS; GLYCOPROTEINS; GREEN FLUORESCENT PROTEINS; LUCIFERASES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; OLIGODENDROGLIOMA; RATS; RATS, INBRED LEW; RNA, VIRAL; TRANSCRIPTION, GENETIC; VERO CELLS; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS;

BORNA DISEASE VIRUS; MAMMALIA; RNA VIRUSES; RODENTIA; VESICULAR STOMATITIS VIRUS;

EID: 81255184484     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.05554-11     Document Type: Article

References (35)

1. Ackermann, A., P. Staeheli, and U. Schneider. 2007. Adaptation of Borna disease virus to new host species attributed to altered regulation of viral polymerase activity. J. Virol. 81:7933-7940.
2. Ackermann, A., T. Guelzow, P. Staeheli, U. Schneider, and B. Heimrich. 2010. Visualizing viral dissemination in the mouse nervous system, using a green fluorescent protein-expressing Borna disease virus vector. J. Virol. 84:5438-5442.
3. Bajramovic, J. J., et al. 2003. Borna disease virus glycoprotein is required for viral dissemination in neurons. J. Virol. 77:12222-12231.
4. Bartlett, E. J., et al. 2007. Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes. Virol. J. 4:67.
5. Braxton, C. L., S. H. Puckett, S. B. Mizel, and D. S. Lyles. 2010. Protection against lethal vaccinia virus challenge by using an attenuated matrix protein mutant vesicular stomatitis virus vaccine vector expressing poxvirus antigens. J. Virol. 84:3552-3561.
6. Clemente, R., and J. C. de la Torre. 2007. Cell-to-cell spread of Borna disease virus proceeds in the absence of the virus primary receptor and furin-mediated processing of the virus surface glycoprotein. J. Virol. 81: 5968-5977.
7. Cubitt, B., C. Oldstone, and J. C. de la Torre. 1994. Sequence and genome organization of Borna disease virus. J. Virol. 68:1382-1396.
8. de la Torre, J. C. 2002. Bornavirus and the brain. J. Infect. Dis. 186:S241-S247.
9. de la Torre, J. C. 2006. Reverse-genetic approaches to the study of Borna disease virus. Nat. Rev. Microbiol. 4:777-783.
10. Etessami, R., et al. 2000. Spread and pathogenic characteristics of a G-deficient rabies virus recombinant: an in vitro and in vivo study. J. Gen. Virol. 81:2147-2153.
11. Fouillot-Coriou, N., and L. Roux. 2000. Structure-function analysis of the Sendai virus F and HN cytoplasmic domain: different role for the two proteins in the production of virus particle. Virology 270:464-475.
12. Garoff, H., R. Hewson, and D. J. Opstelten. 1998. Virus maturation by budding. Microbiol. Mol. Biol. Rev. 62:1171-1190.
13. Gomme, E. A., E. J. Faul, P. Flomenberg, J. P. McGettigan, and M. J. Schnell. 2010. Characterization of a single-cycle rabies virus-based vaccine vector. J. Virol. 84:2820-2831.
14. Gonzalez-Dunia, D., B. Cubitt, F. A. Grasser, and J. C. de la Torre. 1997. Characterization of Borna disease virus p56 protein, a surface glycoprotein involved in virus entry. J. Virol. 71:3208-3218.
15. Gonzalez-Dunia, D., B. Cubitt, and J. C. de la Torre. 1998. Mechanism of Borna disease virus entry into cells. J. Virol. 72:783-788.
16. Honda, T., M. Horie, T. Daito, K. Ikuta, and K. Tomonaga. 2009. Molecular chaperone BiP interacts with Borna disease virus glycoprotein at the cell surface. J. Virol. 83:12622-12625.
17. Iverson, L. E., and J. K. Rose. 1981. Localized attenuation and discontinuous synthesis during vesicular stomatitis virus transcription. Cell 23:477-484.
18. Ludwig, H., and L. Bode. 2000. Borna disease virus: new aspects on infection, disease, diagnosis and epidemiology. Rev. Sci. Tech. 19:259-288.
19. Makino, A., T. Horimoto, and Y. Kawaoka. 2009. Binding properties of GP1 protein of Borna disease virus. J. Vet. Med. Sci. 71:243-246.
20. Martin, A., N. Hoefs, J. Tadewaldt, P. Staeheli, and U. Schneider. 2011. Genomic RNAs of Borna disease virus are elongated on internal template motifs after realignment of the 3′ termini. Proc. Natl. Acad. Sci. U. S. A. 108:7206-7211.
21. Nishino, Y., D. Kobasa, S. A. Rubin, M. V. Pletnikov, and K. M. Carbone. 2002. Enhanced neurovirulence of Borna disease virus variants associated with nucleotide changes in the glycoprotein and L polymerase genes. J. Virol. 76:8650-8658.
22. Perez, M., M. Watanabe, M. A. Whitt, and J. C. de la Torre. 2001. N-terminal domain of Borna disease virus G (p56) protein is sufficient for virus receptor recognition and cell entry. J. Virol. 75:7078-7085.
23. Roberts, A., J. D. Reuter, J. H. Wilson, S. Baldwin, and J. K. Rose. 2004. Complete protection from papillomavirus challenge after a single vaccination with a vesicular stomatitis virus vector expressing high levels of L1 protein. J. Virol. 78:3196-3199.
24. Rosario, D., M. Perez, and J. C. de la Torre. 2005. Functional characterization of the genomic promoter of borna disease virus (BDV): implications of 3′-terminal sequence heterogeneity for BDV persistence. J. Virol. 79:6544-6550.
25. Schneider, U., M. Schwemmle, and P. Staeheli. 2005. Genome trimming: a unique strategy for replication control employed by Borna disease virus. Proc. Natl. Acad. Sci. U. S. A. 102:3441-3446.
26. Schneider, U., A. Ackermann, and P. Staeheli. 2007. A Borna disease virus vector for expression of foreign genes in neurons of rodents. J. Virol. 81: 7293-7296.
27. Schneider, U., A. Martin, M. Schwemmle, and P. Staeheli. 2007. Genome trimming by Borna disease viruses: viral replication control or escape from cellular surveillance? Cell. Mol. Life. Sci. 64:1038-1042.
28. Schnell, M. J., et al. 1998. Requirement for a non-specific glycoprotein cytoplasmic domain sequence to drive efficient budding of vesicular stomatitis virus. EMBO. J. 17:1289-1296.
29. Tokusumi, T., et al. 2002. Recombinant Sendai viruses expressing different levels of a foreign reporter gene. Virus. Res. 86:33-38.
30. Tomonaga, K., et al. 2000. Identification of alternative splicing and negative splicing activity of a nonsegmented negative-strand RNA virus, Borna disease virus. Proc. Natl. Acad. Sci. U. S. A. 97:12788-12793.
31. Tomonaga, K., T. Kobayashi, and K. Ikuta. 2002. Molecular and cellular biology of Borna disease virus infection. Microbes Infect. 4:491-500.
32. Walker, M. P., I. Jordan, T. Briese, N. Fischer, and W. I. Lipkin. 2000. Expression and characterization of the Borna disease virus polymerase. J. Virol. 74:4425-4428.
33. Wertz, G. W., R. Moudy, and L. A. Ball. 2002. Adding genes to the RNA genome of vesicular stomatitis virus: positional effects on stability of expression. J. Virol. 76:7642-7650.
34. Yanai, H., et al. 2006. Development of a novel Borna disease virus reverse genetics system using RNA polymerase II promoter and SV40 nuclear import signal. Microbes Infect. 8:1522-1529.
35. Yoshizaki, M., et al. 2006. Naked Sendai virus vector lacking all of the envelope-related genes: reduced cytopathogenicity and immunogenicity. J. Gene Med. 8:1151-1159.