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Volumn 155, Issue 2, 2014, Pages 1053-1060

Huangqi-Honghua combination and its main components ameliorate cerebral infarction with Qi deficiency and blood stasis syndrome by antioxidant action in rats

Author keywords

Astragaloside IV; Carthamus tinctorius L.; Cerebral infarction; Hydroxysafflor yellow A; Qi deficiency and blood stasis syndrome; Radix Astragali

Indexed keywords

ASTRAGALOSIDE IV; ASTRAGALUS EXTRACT; CATALASE; GLUTATHIONE PEROXIDASE; HYDROXYSAFFLOR YELLOW A; MALONALDEHYDE; PLANT MEDICINAL PRODUCT; REACTIVE OXYGEN METABOLITE; SAFFLOWER EXTRACT; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; HERBACEOUS AGENT; HONGHUA EXTRACT, CARTHAMUS TINCTORIUS; HUANG QI;

EID: 84906940221     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.05.061     Document Type: Article
Times cited : (79)

References (44)
  • 1
    • 0037338554 scopus 로고    scopus 로고
    • Neuroprotective effect of SolCD39, a novel platelet aggregation inhibitor, on transient middle cerebral artery occlusion in rats
    • L. Belayev, L. Khoutorova, T.A. Deisher, A. Belayev, R. Busto, Y. Zhang, W. Zhao, and M.D. Ginsberg Neuroprotective effect of SolCD39, a novel platelet aggregation inhibitor, on transient middle cerebral artery occlusion in rats Stroke 34 2003 758 763
    • (2003) Stroke , vol.34 , pp. 758-763
    • Belayev, L.1    Khoutorova, L.2    Deisher, T.A.3    Belayev, A.4    Busto, R.5    Zhang, Y.6    Zhao, W.7    Ginsberg, M.D.8
  • 2
    • 34547821365 scopus 로고    scopus 로고
    • Buyang Huanwu Decoction can improve recovery of neurological function, reduce infarction volume, stimulate neural proliferation and modulate VEGF and Flk1 expressions in transient focal cerebral ischaemic rat brains
    • G. Cai, B. Liu, W. Liu, X. Tan, J. Rong, X. Chen, L. Tong, and J. Shen Buyang Huanwu Decoction can improve recovery of neurological function, reduce infarction volume, stimulate neural proliferation and modulate VEGF and Flk1 expressions in transient focal cerebral ischaemic rat brains Journal of Ethnopharmacology 113 2007 292 299
    • (2007) Journal of Ethnopharmacology , vol.113 , pp. 292-299
    • Cai, G.1    Liu, B.2    Liu, W.3    Tan, X.4    Rong, J.5    Chen, X.6    Tong, L.7    Shen, J.8
  • 3
    • 79952850719 scopus 로고    scopus 로고
    • Oxidative stress in ischemic brain damage: Mechanisms of cell death and potential molecular targets for neuroprotection
    • H. Chen, H. Yoshioka, G.S. Kim, J.E. Jung, N. Okami, H. Sakata, and C.M. Maier Oxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotection Antioxidants & Redox Signaling 14 2011 1505 1517
    • (2011) Antioxidants & Redox Signaling , vol.14 , pp. 1505-1517
    • Chen, H.1    Yoshioka, H.2    Kim, G.S.3    Jung, J.E.4    Okami, N.5    Sakata, H.6    Maier, C.M.7
  • 4
    • 84885955456 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A protects against cerebral ischemia-reperfusion injury by anti-apoptotic effect through P13K/Akt/GSK3β pathway in rat
    • L. Chen, L. Xiang, L. Kong, X. Zhang, B. Sun, X. Wei, and H. Liu Hydroxysafflor yellow A protects against cerebral ischemia-reperfusion injury by anti-apoptotic effect through P13K/Akt/GSK3β pathway in rat Neurochemical Research 38 2013 2268 2275
    • (2013) Neurochemical Research , vol.38 , pp. 2268-2275
    • Chen, L.1    Xiang, L.2    Kong, L.3    Zhang, X.4    Sun, B.5    Wei, X.6    Liu, H.7
  • 6
    • 0036201591 scopus 로고    scopus 로고
    • Preconditioning with hyperbaric oxygen and hyperoxia induces tolerance against spinal cord ischemia in rabbits
    • H. Dong, L. Xiong, Z. Zhu, S. Chen, L. Hou, and T. Sakabe Preconditioning with hyperbaric oxygen and hyperoxia induces tolerance against spinal cord ischemia in rabbits Anesthesiology 96 2002 907 912
    • (2002) Anesthesiology , vol.96 , pp. 907-912
    • Dong, H.1    Xiong, L.2    Zhu, Z.3    Chen, S.4    Hou, L.5    Sakabe, T.6
  • 8
    • 0035515128 scopus 로고    scopus 로고
    • Protection by metal complexes with SOD-mimetic activity against oxidative gastric injury induced by indomethacin and ethanol in rats
    • M.A. El-Missiry, I.H. El-Sayed, and A.I. Othman Protection by metal complexes with SOD-mimetic activity against oxidative gastric injury induced by indomethacin and ethanol in rats Annals of Clinical Biochemistry 38 2001 694 700
    • (2001) Annals of Clinical Biochemistry , vol.38 , pp. 694-700
    • El-Missiry, M.A.1    El-Sayed, I.H.2    Othman, A.I.3
  • 9
    • 84870295559 scopus 로고    scopus 로고
    • Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats
    • C. Guo, L. Tong, M.M. Xi, H.F. Yang, H.L. Dong, and A.D. Wen Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats Journal of Ethnopharmacology 144 2012 768 774
    • (2012) Journal of Ethnopharmacology , vol.144 , pp. 768-774
    • Guo, C.1    Tong, L.2    Xi, M.M.3    Yang, H.F.4    Dong, H.L.5    Wen, A.D.6
  • 10
    • 0028792111 scopus 로고
    • Lipid peroxidation and antioxidants as biomarkers of tissue damage
    • J.M. Gutteridge Lipid peroxidation and antioxidants as biomarkers of tissue damage Clinical Chemistry 41 1995 1819 1828
    • (1995) Clinical Chemistry , vol.41 , pp. 1819-1828
    • Gutteridge, J.M.1
  • 11
    • 84872965457 scopus 로고    scopus 로고
    • Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats
    • S.Y. Han, H.X. Li, X. Ma, K. Zhang, Z.Z. Ma, Y. Jiang, and P.F. Tu Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats Journal of Ethnopharmacology 145 2013 722 727
    • (2013) Journal of Ethnopharmacology , vol.145 , pp. 722-727
    • Han, S.Y.1    Li, H.X.2    Ma, X.3    Zhang, K.4    Ma, Z.Z.5    Jiang, Y.6    Tu, P.F.7
  • 12
    • 84906940686 scopus 로고    scopus 로고
    • 32 cases of acute cerebral infarction treated with Huangqi and Honghua Injection
    • Q. Hu, J.H. Zhao, and L.J. Zou 32 cases of acute cerebral infarction treated with Huangqi and Honghua Injection China Modern Doctor 46 2 2008 70
    • (2008) China Modern Doctor , vol.46 , Issue.2 , pp. 70
    • Hu, Q.1    Zhao, J.H.2    Zou, L.J.3
  • 13
    • 85039836509 scopus 로고    scopus 로고
    • Huangqi Injection combined Honghua Injection treatment of 32 cases of acute cerebral infarction
    • Q. Hu, J.H. Zhao, and L.J. Zou Huangqi Injection combined Honghua Injection treatment of 32 cases of acute cerebral infarction China Modern Doctor 46 2008 70 71
    • (2008) China Modern Doctor , vol.46 , pp. 70-71
    • Hu, Q.1    Zhao, J.H.2    Zou, L.J.3
  • 16
    • 69449089391 scopus 로고    scopus 로고
    • Rutin protects the neural damage induced by transient focal ischemia in rats
    • M.M. Khan, A. Ahmad, T. Ishrat, G. Khuwaja, and P. Srivastava et al. Rutin protects the neural damage induced by transient focal ischemia in rats Brain Research 1292 2009 123 135
    • (2009) Brain Research , vol.1292 , pp. 123-135
    • Khan, M.M.1    Ahmad, A.2    Ishrat, T.3    Khuwaja, G.4    Srivastava, P.5
  • 17
    • 84906935100 scopus 로고    scopus 로고
    • The effect of Radix Astragali and Safflower Injection on neuron apoptosis and caspase-8 after local cerebral ischemia/reperfusion in rats
    • Z. Lai, L.S. Li, and S.B. Cheng The effect of Radix Astragali and Safflower Injection on neuron apoptosis and caspase-8 after local cerebral ischemia/reperfusion in rats Chinese Journal of Arteriosclerosis 16 2008 885 888
    • (2008) Chinese Journal of Arteriosclerosis , vol.16 , pp. 885-888
    • Lai, Z.1    Li, L.S.2    Cheng, S.B.3
  • 18
    • 68649103943 scopus 로고    scopus 로고
    • Effect of the carthamins yellow from Carthamus tinctorius L. on hemorheological disorders of blood stasis in rats
    • H.X. Li, S.Y. Han, X.W. Wang, X. Ma, K. Zhang, L. Wang, Z.Z. Ma, and P.F. Tu Effect of the carthamins yellow from Carthamus tinctorius L. on hemorheological disorders of blood stasis in rats Food and Chemical Toxicology 47 2009 1797 1802
    • (2009) Food and Chemical Toxicology , vol.47 , pp. 1797-1802
    • Li, H.X.1    Han, S.Y.2    Wang, X.W.3    Ma, X.4    Zhang, K.5    Wang, L.6    Ma, Z.Z.7    Tu, P.F.8
  • 19
    • 84867022857 scopus 로고    scopus 로고
    • Reperfusion promotes mitochondrial dysfunction following focal cerebral ischemia in rats
    • J. Li, X.S. Ma, W. Yu, Z.Q. Lou, D.L. Mu, Y. Wang, B.,Z. Shen, and S.H. Qi Reperfusion promotes mitochondrial dysfunction following focal cerebral ischemia in rats Plos One 7 2012 1 10
    • (2012) Plos One , vol.7 , pp. 1-10
    • Li, J.1    Ma, X.S.2    Yu, W.3    Lou, Z.Q.4    Mu, D.L.5    Wang, Y.6    Shen, B.Z.7    Qi, S.H.8
  • 20
    • 33746454283 scopus 로고    scopus 로고
    • Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid
    • J.J. Li, Q. Tang, Y. Li, B.R. Hu, Z.Y. Ming, Q. Fu, J.Q. Qian, and J.Z. Xiang Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid Acta Pharmacologica Sinica 27 2006 1078 1084
    • (2006) Acta Pharmacologica Sinica , vol.27 , pp. 1078-1084
    • Li, J.J.1    Tang, Q.2    Li, Y.3    Hu, B.R.4    Ming, Z.Y.5    Fu, Q.6    Qian, J.Q.7    Xiang, J.Z.8
  • 22
    • 84906933696 scopus 로고    scopus 로고
    • The clinical observation of Huangqi Injection and Honghua Injection combination for treatment the cerebral ischemia
    • Y.J. Liang, J. Li, and J.C. Liang The clinical observation of Huangqi Injection and Honghua Injection combination for treatment the cerebral ischemia Modern Journal of Integrated Traditional Chinese and Western Medicine 16 2007 196 197
    • (2007) Modern Journal of Integrated Traditional Chinese and Western Medicine , vol.16 , pp. 196-197
    • Liang, Y.J.1    Li, J.2    Liang, J.C.3
  • 23
    • 0034697372 scopus 로고    scopus 로고
    • Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. Membranaceus
    • L.Z. Lin, X.G. He, M. Lindenmaier, G. Nolan, J. Yang, M. Cleary, S.X. Qiu, and G.A. Cordell Liquid chromatography-electrospray ionization mass spectrometry study of the flavonoids of the roots of Astragalus mongholicus and A. Membranaceus Journal of Chromatography A 876 2000 87 95
    • (2000) Journal of Chromatography A , vol.876 , pp. 87-95
    • Lin, L.Z.1    He, X.G.2    Lindenmaier, M.3    Nolan, G.4    Yang, J.5    Cleary, M.6    Qiu, S.X.7    Cordell, G.A.8
  • 24
    • 84855994068 scopus 로고    scopus 로고
    • Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation
    • L. Liu, J.A. Duan, Y.P. Tang, J.M. Guo, N.Y. Yang, H.Y. Ma, and X.Q. Shi Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation Journal of Ethnopharmacology 139 2012 381 387
    • (2012) Journal of Ethnopharmacology , vol.139 , pp. 381-387
    • Liu, L.1    Duan, J.A.2    Tang, Y.P.3    Guo, J.M.4    Yang, N.Y.5    Ma, H.Y.6    Shi, X.Q.7
  • 25
    • 84906936568 scopus 로고    scopus 로고
    • Theory discuss of the Pathogenesis theory of deficiency of qi and blood stasis in ischemic stroke
    • S.Z. Liu, Z.X. Bao, and R.L. Zhang Theory discuss of the Pathogenesis theory of deficiency of qi and blood stasis in ischemic stroke Chinese Archives of Traditional Chinese Medicine 25 2007 97 98
    • (2007) Chinese Archives of Traditional Chinese Medicine , vol.25 , pp. 97-98
    • Liu, S.Z.1    Bao, Z.X.2    Zhang, R.L.3
  • 27
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • E.Z. Longa, P.R. Weinstein, S. Carlson, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 89
    • (1989) Stroke , vol.20 , pp. 84-89
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 28
    • 2942596217 scopus 로고    scopus 로고
    • Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia
    • Y.M. Luo, Z. Qin, Z. Hong, X.M. Zhang, D. Ding, J.H. Fu, W.D. Zhang, and J. Chen Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia Neuroscience Letters 363 2004 218 223
    • (2004) Neuroscience Letters , vol.363 , pp. 218-223
    • Luo, Y.M.1    Qin, Z.2    Hong, Z.3    Zhang, X.M.4    Ding, D.5    Fu, J.H.6    Zhang, W.D.7    Chen, J.8
  • 29
    • 84906933892 scopus 로고    scopus 로고
    • The effect observation of Astragahs mongholicus and red flower on apoptosis of nerve cells around the cerebral hemorrhage hemorrhage in rat
    • Q.R. Ma, J.P. Sun, J.B. Ma, G.H. Liu, L. Liang, J. Zhao, X.W. Ma, and Y. Qin The effect observation of Astragahs mongholicus and red flower on apoptosis of nerve cells around the cerebral hemorrhage hemorrhage in rat Chinese Journal of Clinical Rational Drug Use 6 12A 2013 1 3
    • (2013) Chinese Journal of Clinical Rational Drug Use , vol.6 A , Issue.12 , pp. 1-3
    • Ma, Q.R.1    Sun, J.P.2    Ma, J.B.3    Liu, G.H.4    Liang, L.5    Zhao, J.6    Ma, X.W.7    Qin, Y.8
  • 31
    • 0031251788 scopus 로고    scopus 로고
    • A novel method for counting spontaneous motor activity in the rat
    • Y. Masuo, Y. Matsumoto, S. Morita, and J. Noguchi A novel method for counting spontaneous motor activity in the rat Brain Research 1 1997 321 326
    • (1997) Brain Research , vol.1 , pp. 321-326
    • Masuo, Y.1    Matsumoto, Y.2    Morita, S.3    Noguchi, J.4
  • 32
    • 77953657635 scopus 로고    scopus 로고
    • Retrospective analysis on integrative medicinal treatment of chronic heart failure
    • Y. Miao, W.J. Zhao, and L. Jing Retrospective analysis on integrative medicinal treatment of chronic heart failure Zhongguo Zhong Xi Yi Jie He Za Zhi 28 2008 406 409
    • (2008) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.28 , pp. 406-409
    • Miao, Y.1    Zhao, W.J.2    Jing, L.3
  • 34
    • 59649105210 scopus 로고    scopus 로고
    • Chinese medicinal formula Guan-Xin-Er-Hao protects the heart against oxidative stress induced by acute ischemic myocardial injury in rats
    • F. Qin, Y.X. Liu, H.W. Zhao, X. Huang, P. Ren, and Z.Y. Zhu Chinese medicinal formula Guan-Xin-Er-Hao protects the heart against oxidative stress induced by acute ischemic myocardial injury in rats Phytomedicine 16 2009 215 221
    • (2009) Phytomedicine , vol.16 , pp. 215-221
    • Qin, F.1    Liu, Y.X.2    Zhao, H.W.3    Huang, X.4    Ren, P.5    Zhu, Z.Y.6
  • 35
    • 60949092865 scopus 로고    scopus 로고
    • Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats
    • Y.Z. Qu, M. Li, Y.,L. Zhao, Z.W. Zhao, X.Y. Wei, and J.P. Liu Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats European Journal of Pharmacology 606 2009 137 141
    • (2009) European Journal of Pharmacology , vol.606 , pp. 137-141
    • Qu, Y.Z.1    Li, M.2    Zhao, Y.L.3    Zhao, Z.W.4    Wei, X.Y.5    Liu, J.P.6
  • 36
    • 84872332879 scopus 로고    scopus 로고
    • Neuroprotective effect of naringenin is mediated through suppression of NF-kB signaling pathway in experimental stroke
    • S.S. Raza, M.M. Khan, A. Ahmad, M. Ashafaq, F. Islam, A.P. Wagner, M.M. Safhi, and F. Islam Neuroprotective effect of naringenin is mediated through suppression of NF-kB signaling pathway in experimental stroke Neuroscience 230 2013 157 171
    • (2013) Neuroscience , vol.230 , pp. 157-171
    • Raza, S.S.1    Khan, M.M.2    Ahmad, A.3    Ashafaq, M.4    Islam, F.5    Wagner, A.P.6    Safhi, M.M.7    Islam, F.8
  • 37
    • 35548957889 scopus 로고    scopus 로고
    • Astrocyte metabolism and signaling during brain ischemia
    • D.J. Rossi, J.D. Brady, and C. Mohr Astrocyte metabolism and signaling during brain ischemia Nature Neuroscience 10 2007 1377 1386
    • (2007) Nature Neuroscience , vol.10 , pp. 1377-1386
    • Rossi, D.J.1    Brady, J.D.2    Mohr, C.3
  • 38
    • 50249154155 scopus 로고    scopus 로고
    • Isolation of mitochondria from rat brain using percoll density gradient centrifugation
    • N.R. Sims, and M.F. Anderson Isolation of mitochondria from rat brain using percoll density gradient centrifugation Nature Protocols 3 2008 1228 1239
    • (2008) Nature Protocols , vol.3 , pp. 1228-1239
    • Sims, N.R.1    Anderson, M.F.2
  • 40
    • 22544451583 scopus 로고    scopus 로고
    • Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action
    • X.B. Wei, H.Q. Liu, X. Sun, F.H. Fu, X.M. Zhang, J. Wang, J. An, and H. Ding Hydroxysafflor yellow A protects rat brains against ischemia-reperfusion injury by antioxidant action Neuroscience Letters 386 2005 58 62
    • (2005) Neuroscience Letters , vol.386 , pp. 58-62
    • Wei, X.B.1    Liu, H.Q.2    Sun, X.3    Fu, F.H.4    Zhang, X.M.5    Wang, J.6    An, J.7    Ding, H.8
  • 41
    • 84862823621 scopus 로고    scopus 로고
    • Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia
    • J.H. Yang, J.H. Li, J. Lu, Y.Y. Zhang, Z.H. Zhu, and H.T. Wan Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia Journal of Ethnopharmacology 140 2012 64 72
    • (2012) Journal of Ethnopharmacology , vol.140 , pp. 64-72
    • Yang, J.H.1    Li, J.H.2    Lu, J.3    Zhang, Y.Y.4    Zhu, Z.H.5    Wan, H.T.6
  • 42
    • 77957841900 scopus 로고    scopus 로고
    • Neuroprotective effect of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors
    • Q. Yang, Z.F. Yang, S.B. Liu, X.N. Zhang, Y. Hou, X.Q. Li, Y.M. Wu, A.D. Wen, and M.G. Zhao Neuroprotective effect of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors Neurochemical Research 35 2010 1353 1360
    • (2010) Neurochemical Research , vol.35 , pp. 1353-1360
    • Yang, Q.1    Yang, Z.F.2    Liu, S.B.3    Zhang, X.N.4    Hou, Y.5    Li, X.Q.6    Wu, Y.M.7    Wen, A.D.8    Zhao, M.G.9
  • 43
    • 77953808121 scopus 로고    scopus 로고
    • Buyang Huanwu decoction ameliorates coronary heart disease with Qi deficiency and blood stasis syndrome by reducing CRP and CD40 in rat
    • H. Zhang, W.,R. Wang, R. Lin, J.,Y. Zhang, Q.,L. Ji, Q.,Q. Lin, and L.,N. Yang Buyang Huanwu decoction ameliorates coronary heart disease with Qi deficiency and blood stasis syndrome by reducing CRP and CD40 in rat Journal of Ethnopharmacology 130 2010 98 102
    • (2010) Journal of Ethnopharmacology , vol.130 , pp. 98-102
    • Zhang, H.1    Wang, W.R.2    Lin, R.3    Zhang, J.Y.4    Ji, Q.L.5    Lin, Q.Q.6    Yang, L.N.7


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