Evaluation of the anti-myocardial ischemia effect of individual and combined extracts of Panax notoginseng and Carthamus tinctorius in rats

Journal of Ethnopharmacology

Volumn 145, Issue 3, 2013, Pages 722-727

  Han, Shu Yan ^a,b   Li, Hai Xia ^a   Ma, Xu ^a   Zhang, Ke ^a   Ma, Zhi Zhong ^a   Jiang, Yong ^a   Tu, Peng Fei ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Carthamus tinctorius; Heart function; Inflammatory cytokines; Myocardial infarction; Oxidative stress; Panax notoginseng

Indexed keywords

C REACTIVE PROTEIN; CREATINE KINASE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; MALONALDEHYDE; PANAX NOTOGINSENG EXTRACT; SAFFLOWER EXTRACT; SUPEROXIDE DISMUTASE; TRIPHENYLTETRAZOLIUM; TROPONIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; ENZYME ACTIVITY; EVALUATION; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEMODYNAMICS; INFLAMMATION; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; MONOTHERAPY; NONHUMAN; OXIDATIVE STRESS; RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; C-REACTIVE PROTEIN; CARDIOTONIC AGENTS; CARTHAMUS TINCTORIUS; CREATINE KINASE; DRUG COMBINATIONS; INTERLEUKIN-1BETA; L-LACTATE DEHYDROGENASE; MALE; MYOCARDIAL ISCHEMIA; OXIDATIVE STRESS; PANAX NOTOGINSENG; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TROPONIN I; TUMOR NECROSIS FACTOR-ALPHA;

ANGINA; CARTHAMUS TINCTORIUS; PANAX NOTOGINSENG; RATTUS;

EID: 84872965457     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.11.036     Document Type: Article

References (40)

1. V. Braunersreuther, F. Mach, and F. Montecucco Reactive oxygen-induced cardiac intracellular pathways during ischemia and reperfusion Current Signal Transduction Therapy 7 2012 89 95
2. Combination Pharmacotherapy and Public Health Research Working Group Combination pharmacotherapy for cardiovascular disease Annals of Internal Medicine 143 2005 593 599
3. N.S. Dhalla, A.B. Elmoselhi, T. Hata, and N. Makino Status of myocardial antioxidants in ischemia-reperfusion injury Cardiovascular Research 47 2000 446 456 (Pubitemid 30646067)
4. L. Fan, H.Y. Zhao, M. Xu, L. Zhou, H. Guo, J. Han, B.R. Wang, and D.A. Guo Qualitative evaluation and quantitative determination of 10 major active components in Carthamus tinctorius L. by high-performance liquid chromatography coupled with diode array detector Journal of Chromatography 1216 2009 2063 2070
5. Q. Feng, X. Lu, D.L. Jones, J. Shen, and J.M. Arnold Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice Circulation 104 2001 700 704 (Pubitemid 32738526)
6. R. Ferrari, G. Guardigli, D. Mele, G.F. Percoco, C. Ceconi, and S. Curello Oxidative stress during myocardial ischaemia and heart failure Current Pharmaceutical Design 10 2004 1699 1711 (Pubitemid 38559780)
7. J.H. Fu, Q. Zhang, C.Z. Fan, and J.G. Liu Protective effect of intravenous infusion injection of safflor yellow and hydroxyl safflor yellow A on acute myocardial ischemia injury in rats International Journal of Traditional Chinese Medicine 33 2011 692 694
8. S.Y. Han, H.X. Li, X. Ma, K. Zhang, Z.Z. Ma, and P.F. Tu Protective effects of purified safflower extract on myocardial ischemia in vivo and in vitro Phytomedicine 16 2009 694 702
9. S.Y. Han, H.X. Li, C.C. Bai, L. Wang, and P.F. Tu Component analysis and free radical-scavenging potential of Panax notoginseng and Carthamus tinctorius extracts Chemistry and Biodiversity 7 2010 383 391
10. S.Y. Han, H.X. Li, and P.F. Tu Ameliorative effects of Panax notoginseng saponins combined with Carthamus tinctorius flavonoids on hemorheology in rats with acute blood stasis Chinese Journal of Pharmacology and Toxicology 25 2011 62 67
11. G.M. Hirschfield, and M.B. Pepys C-reactive protein and cardiovascular disease: new insights from an old molecule Quaterly Journal of Medicine 96 2003 793 807 (Pubitemid 37369294)
12. M. Hori, and K. Nishida Oxidative stress and left ventricular remodelling after myocardial infarction Cardiovascular Research 81 2009 457 464
13. C. Huang, H. Tsai, R. Pen, Y.H. Hsieh, W. Chuang, G. Hsu, W. Huang, and W. Chen Agaricus Blazei Murill ameliorates myocardial ischemia-reperfusion injury Acta. Cardiologica. Sinica. 26 2010 235 241
14. K. Ishii, T. Suyama, M. Imai, M. Maenaka, A. Yamanaka, Y. Makino, Y. Seino, K. Shimada, and J. Yoshikawa Abnormal regional left ventricular systolic and diastolic function in patients with coronary artery disease undergoing percutaneous coronary intervention: clinical significance of post-ischemic diastolic stunning Journal of American College of Cardiology 54 2009 1589 1597
15. K.A. Kaminski, T.A. Bonda, J. Korecki, and W.J. Musial Oxidative stress and neutrophil activation-the two keystones of ischemia/reperfusion injury International Journal of Cardiology 86 2002 41 59 (Pubitemid 35247882)
16. M. Kawaguchi, M. Takahashi, T. Hata, Y. Kashima, F. Usui, H. Morimoto, A. Izawa, Y. Takahashi, J. Masumoto, J. Koyama, M. Hongo, T. Noda, J. Nakayama, J. Sagara, S. Taniguchi, and U. Ikeda Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury Circulation 123 2011 594 604
17. R.A. Kloner, and S.H. Rezkalla Cardiac protection during acute myocardial infarction: where do we stand in 2004? Journal of American College Of Cardiology 22 2 2004 276 286 (Pubitemid 38950583)
18. X.Z. Li, J.X. Liu, X.H. Shang, and J.H. Fu Protective effects of hydroxysafflor yellow A on acute myocardial ischem ia in dogs Chin. Pharmacol. Bull. 5 2006 533 537
19. S.F. Melanson, and M.J. Tanasijevic Laboratory diagnosis of acute myocardial injury Cardiovascular Pathology 14 2005 156 161 (Pubitemid 40725592)
20. M. Metra, G. Felker, V. Zacà, S. Bugatti, C. Lombardi, L. Bettari, A. Voors, M. Gheorghiade, and L. Dei Cas Acute heart failure: multiple clinical profiles and mechanisms require tailored therapy International Journal Cardiology 144 2010 175 179
21. T.B. Ng Pharmacological activity of sanchi ginseng (Panax notoginseng) Journal of Pharmacy and Pharmacology 58 2006 1007 1019 (Pubitemid 44213633)
22. M. Nian, P. Lee, N. Khaper, and P. Liu Inflammatory cytokines and postmyocardial infarction remodeling Circulation Research 94 2004 1543 1553 (Pubitemid 38856961)
23. M.R. Rao, and M.D. Liang Effects of saponins of Panax notoginseng on cardiac hemodynamics, acute myocardial infarction and their calcium antagonistic action Journal of Molecular and Cellular Cardiology 18 1986 108
24. A. Rhule, S. Navarro, J.R. Smith, and D.M. Shepherd Panax notoginseng attenuates LPS-induced pro-inflammatory mediators in RAW264.7 cells Journal of Ethnopharmacology 106 2006 121 128
25. S. Rutschow, J. Li, H.P. Schultheiss, and M. Pauschinger Myocardial proteases and matrix remodeling in inflammatory heart disease Cardiovascular Research 69 2006 646 656 (Pubitemid 43139727)
26. S.A. Samsamshariat, Z.A. Samsamshariat, and M.R. Movahed A novel method for safe and accurate left anterior descending coronary artery ligation for research in rats Cardiovascular Revascularization Medicine 6 2005 121 123 (Pubitemid 41579081)
27. M. Spinella The importance of pharmacological synergy in psychoactive herbal medicines Alternative Medicine Review 7 2002 130 137 (Pubitemid 34461524)
28. Y.J. Surh Reverse pharmacology applicable for botanical drug development - inspiration from the legacy of traditional wisdom J. Trad. Comp. Med. 1 2011 5 7
29. T. Urdulashvili, N. Momtselidze, M. Mantskava, N. Narsia, and G. McHedlishvili Hemorheological disorders and arteriolar resistance during ischemic heart disease Clinical Hemorheology Microcircular 30 2004 399 401 (Pubitemid 38951533)
30. E.J. Velazquez, G.S. Francis, P.W. Armstrong, P.E. Aylward, R. Diaz, C.M. O'Connor, H.D. White, M. Henis, L.M. Rittenhouse, R. Kilaru, W. van Gilst, G. Ertl, A.P. Maggioni, J. Spac, W.D. Weaver, J.L. Rouleau, J.J. McMurray, M.A. Pfeffer, and R.M. Califf An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry European Heart Journal 25 2004 1911 1919 (Pubitemid 39452608)
31. H. Wagner, R. Bauer, P.G. Xiao, J.M. Chen, and S. Bächer Flos Carthami (Honghua), (Einzelexemplar) Drug Monographs and Analysis 7 42 2006 Verlag für Ganzheitliche Medizin, Kötzting/Bayer, Wald
32. H. Wagner, and G. Ulrich-Merzenich Synergy research: approaching a new generation of phytopharmaceuticals Phytomedicine 16 2009 97 110
33. H. Wagner Synergy research: approaching a new generation of phytopharmaceuticals Fitoterapia. 82 2011 34 37
34. N.J. Wald, and M.R. Law A strategy to reduce cardiovascular disease by more than 80% British Medical Journal 326 2003 1419 1424
35. D. Wang, P.Y. Liao, H.T. Zhu, K.K. Chen, M. Xu, Y.J. Zhang, and C.R. Yang The processing of Panax notoginseng and the transformation of its saponin components Food Chemistry 132 2012 1808 1813
36. J.T. Willerson, and P.M. Ridker Inflammation as a cardiovascular risk factor Circulation 109 2004 II2 II10
37. C.H. Woo, Y.W. Eom, M.H. Yoo, H.J. You, H.J. Han, W.K. Song, Y.J. Yoo, J.S. Chun, and J.H. Kim Tumor necrosis factor-generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade Journal of Biological Chemistry 275 2000 32357 32362
38. L. Wu, H. Qiao, Y. Li, and L. Li Protective roles of puerarin and Danshensu on acute ischemic myocardial injury in rats Phytomedicine 14 2007 652 658 (Pubitemid 47419302)
39. K. Yagi Assay for blood plasma or serum Methods in Enzymology 105 1984 328 331 (Pubitemid 14165394)
40. N.N. Zhang, B.T. Andresen, and C.H. Zhang Inflammation and reactive oxygen species in cardiovascular disease World Journal of Cardiology 2 2010 408 410