Association between shear stress and platelet-derived transforming growth factor-β1 release and activation in animal models of aortic valve stenosis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 9, 2014, Pages 1924-1932

  Wang, Wei ^a   Vootukuri, Spandana ^a   Meyer, Alexander ^a   Ahamed, Jasimuddin ^a   Coller, Barry S ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

aortic valve stenosis; blood platelets; transforming growth factor beta

Indexed keywords

COLLAGEN; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN DERIVATIVE; TRANSFORMING GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; AORTA VALVE STENOSIS; ARTERIAL WALL THICKENING; ARTICLE; CONTROLLED STUDY; HYPERCHOLESTEROLEMIA; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SHEAR STRESS;

AORTIC VALVE STENOSIS; BLOOD PLATELETS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALS; AORTIC VALVE; AORTIC VALVE STENOSIS; APOLIPOPROTEIN B-100; BLOOD PLATELETS; CALCINOSIS; COLLAGEN; DIET, ATHEROGENIC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FIBROSIS; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEMORHEOLOGY; HYPERCHOLESTEROLEMIA; LEUKOCYTES; MAP KINASE SIGNALING SYSTEM; MICE; RECEPTORS, LDL; SIGNAL TRANSDUCTION; SMAD PROTEINS; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84906939985     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303852     Document Type: Article

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