Hypercholesterolemia leads to elevated TGF-β1 activity and T helper 3-dependent autoimmune responses in atherosclerotic mice

Atherosclerosis

Volumn 204, Issue 2, 2009, Pages 381-387

  Zhou, Xinghua ^a   Johnston, Thomas P ^b   Johansson, Daniel ^a   Parini, Paolo ^a   Funa, Keiko ^c   Svensson, Jan ^a   Hansson, Göran K ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Atherosclerosis; Autoantibodies; Hypercholesterolemia; Lipoprotein oxidation; T lymphocytes

Indexed keywords

IMMUNOGLOBULIN G2B; OXIDIZED LOW DENSITY LIPOPROTEIN; POLOXAMER; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; HYPERCHOLESTEROLEMIA; IMMUNE RESPONSE; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH3 CELL; UPREGULATION;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; AUTOANTIBODIES; AUTOIMMUNITY; CHOLESTEROL, DIETARY; COLLAGEN; DISEASE MODELS, ANIMAL; HYPERCHOLESTEROLEMIA; IMMUNOGLOBULIN G; LIPOPROTEINS, LDL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLOXAMER; SEVERITY OF ILLNESS INDEX; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TH1 CELLS; TH2 CELLS; TRANSFORMING GROWTH FACTOR BETA1; TRIGLYCERIDES; UP-REGULATION;

EID: 67349129697     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.10.017     Document Type: Article

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