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Volumn 63, Issue 9, 2014, Pages 969-975

Engineered T cells for cancer therapy

Author keywords

19th Danish Cancer Society Symposium; Adoptive cell transfer; Chimeric antigen receptor; Gene transfer; Leukemia

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84906937939     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-014-1568-1     Document Type: Review
Times cited : (95)

References (54)
  • 1
    • 33646804507 scopus 로고    scopus 로고
    • Mechanisms of Immune Evasion by Tumors
    • DOI 10.1016/S0065-2776(06)90002-9, PII S0065277606900029
    • Drake CG, Jaffee E, Pardoll DM (2006) Mechanisms of immune evasion by tumors. Adv Immunol 90:51-81 (Pubitemid 43765799)
    • (2006) Advances in Immunology , vol.90 , pp. 51-81
    • Drake, C.G.1    Jaffee, E.2    Pardoll, D.M.3
  • 2
    • 1542404892 scopus 로고    scopus 로고
    • Adoptive immunotherapy: Engineering T cell responses as biologic weapons for tumor mass destruction
    • DOI 10.1016/S1535-6108(03)00113-2, PII S1535610803001132
    • Ho WY, Blattman JN, Dossett ML, Yee C, Greenberg PD (2003) Adoptive immunotherapy: engineering T cell responses as biologic weapons for tumor mass destruction. Cancer Cell 3:431-437 (Pubitemid 38340289)
    • (2003) Cancer Cell , vol.3 , Issue.5 , pp. 431-437
    • Ho, W.Y.1    Blattman, J.N.2    Dossett, M.L.3    Yee, C.4    Greenberg, P.D.5
  • 3
    • 84880733312 scopus 로고    scopus 로고
    • Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology
    • Kalos M, June CH (2013) Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology. Immunity 39:49-60
    • (2013) Immunity , vol.39 , pp. 49-60
    • Kalos, M.1    June, C.H.2
  • 6
    • 0035251532 scopus 로고    scopus 로고
    • Functional expression of chimeric receptor genes in human T cells
    • DOI 10.1016/S0022-1759(00)00343-4, PII S0022175900003434
    • Eshhar Z, Waks T, Bendavid A, Schindler DG (2001) Functional expression of chimeric receptor genes in human T cells. J Immunol Methods 248:67-76 (Pubitemid 32167025)
    • (2001) Journal of Immunological Methods , vol.248 , Issue.1-2 , pp. 67-76
    • Eshhar, Z.1    Waks, T.2    Bendavid, A.3    Schindler, D.G.4
  • 8
    • 84871338258 scopus 로고    scopus 로고
    • Different affinity windows for virus and cancer-specific T-cell receptors: Implications for therapeutic strategies
    • Aleksic M, Liddy N, Molloy PE, Pumphrey N, Vuidepot A, Chang KM, Jakobsen BK (2012) Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies. Eur J Immunol 42:3174-3179
    • (2012) Eur J Immunol , vol.42 , pp. 3174-3179
    • Aleksic, M.1    Liddy, N.2    Molloy, P.E.3    Pumphrey, N.4    Vuidepot, A.5    Chang, K.M.6    Jakobsen, B.K.7
  • 10
    • 15444371764 scopus 로고    scopus 로고
    • Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines
    • Zhao Y, Zheng Z, Robbins PF, Khong HT, Rosenberg SA, Morgan RA (2005) Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines. J Immunol 174:4415-4423 (Pubitemid 40396025)
    • (2005) Journal of Immunology , vol.174 , Issue.7 , pp. 4415-4423
    • Zhao, Y.1    Zheng, Z.2    Robbins, P.F.3    Khong, H.T.4    Rosenberg, S.A.5    Morgan, R.A.6
  • 12
    • 84883866836 scopus 로고    scopus 로고
    • Identification of a titin-derived HLA-A1-presented peptide as a crossreactive target for engineered MAGE A3-Directed T cells
    • doi:10.1126/scitranslmed.3006034
    • Cameron BJ, Gerry AB, Dukes J, Harper JV, Kannan V, Bianchi FC, Grand F, Brewer JE, Gupta M, Plesa G et al (2013) Identification of a titin-derived HLA-A1-presented peptide as a crossreactive target for engineered MAGE A3-Directed T cells. Sci Transl Med 5(197):197ra103. doi:10.1126/scitranslmed. 3006034
    • (2013) Sci Transl Med , vol.5 , Issue.197
    • Cameron, B.J.1    Gerry, A.B.2    Dukes, J.3    Harper, J.V.4    Kannan, V.5    Bianchi, F.C.6    Grand, F.7    Brewer, J.E.8    Gupta, M.9    Plesa, G.10
  • 15
    • 0026064305 scopus 로고
    • The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways
    • Irving BA, Weiss A (1991) The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell 64:891-901 (Pubitemid 121001177)
    • (1991) Cell , vol.64 , Issue.5 , pp. 891-901
    • Irving, B.A.1    Weiss, A.2
  • 16
    • 0026083035 scopus 로고
    • Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides
    • Romeo C, Seed B (1991) Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides. Cell 64:1037-1046 (Pubitemid 121001190)
    • (1991) Cell , vol.64 , Issue.5 , pp. 1037-1046
    • Romeo, C.1    Seed, B.2
  • 21
    • 0032531091 scopus 로고    scopus 로고
    • Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product
    • Finney HM, Lawson ADG, Bebbington CR, Weir ANC (1998) Chimeric receptors providing both primary and costimulatory signaling in T cells from a single gene product. J Immunol 161:2791-2797 (Pubitemid 28425698)
    • (1998) Journal of Immunology , vol.161 , Issue.6 , pp. 2791-2797
    • Finney, H.M.1    Lawson, A.D.G.2    Bebbington, C.R.3    Weir, A.N.C.4
  • 23
    • 33646440024 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
    • Lamers CH, Sleijfer S, Vulto AG, Kruit WH, Kliffen M, Debets R, Gratama JW, Stoter G, Oosterwijk E (2006) Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol 24:e20-e22
    • (2006) J Clin Oncol , vol.24
    • Lamers, C.H.1    Sleijfer, S.2    Vulto, A.G.3    Kruit, W.H.4    Kliffen, M.5    Debets, R.6    Gratama, J.W.7    Stoter, G.8    Oosterwijk, E.9
  • 24
    • 78549278144 scopus 로고    scopus 로고
    • Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells geneticallyengineered to recognize CD19
    • Kochenderfer J, Wilson W, Janik J, Dudley M, Stetler-Stevenson M, Feldman S, Maric I, Raffeld M, Nathan D, Lanier B et al (2010) Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells geneticallyengineered to recognize CD19. Blood 116:4099-4102
    • (2010) Blood , vol.116 , pp. 4099-4102
    • Kochenderfer, J.1    Wilson, W.2    Janik, J.3    Dudley, M.4    Stetler-Stevenson, M.5    Feldman, S.6    Maric, I.7    Raffeld, M.8    Nathan, D.9    Lanier, B.10
  • 25
    • 80051775476 scopus 로고    scopus 로고
    • T cells expressing chimeric receptors establish memory and potent antitumor effects in patients with advanced leukemia
    • doi:10.1126/scitranslmed.3002842
    • Kalos M, Levine BL, Porter DL, Katz S, Grupp SA, Bagg A, June CH (2011) T cells expressing chimeric receptors establish memory and potent antitumor effects in patients with advanced leukemia. Sci Transl Med 3(95):95ra73. doi:10.1126/scitranslmed.3002842
    • (2011) Sci Transl Med , vol.3 , Issue.95
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3    Katz, S.4    Grupp, S.A.5    Bagg, A.6    June, C.H.7
  • 26
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH (2011) Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 365:725-733
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 28
    • 84876005284 scopus 로고    scopus 로고
    • CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
    • doi:10.1126/scitranslmed.3005930
    • Brentjens RJ, Davila ML, Riviere I, Park J, Wang X, Cowell LG, Bartido S, Stefanski J, Taylor C, Olszewska M et al (2013) CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 5(177):177ra138. doi:10.1126/ scitranslmed.3005930
    • (2013) Sci Transl Med , vol.5 , Issue.177
    • Brentjens, R.J.1    Davila, M.L.2    Riviere, I.3    Park, J.4    Wang, X.5    Cowell, L.G.6    Bartido, S.7    Stefanski, J.8    Taylor, C.9    Olszewska, M.10
  • 29
    • 0030823184 scopus 로고    scopus 로고
    • Replicative senescence of T cells: Does the Hayflick Limit lead to immune exhaustion?
    • DOI 10.1016/S0167-5699(97)01079-7, PII S0167569997010797
    • Effros RB, Pawelec G (1997) Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? Immunol Today 18:450-454 (Pubitemid 27381988)
    • (1997) Immunology Today , vol.18 , Issue.9 , pp. 450-454
    • Effros, R.B.1    Pawelec, G.2
  • 30
    • 80455179612 scopus 로고    scopus 로고
    • Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
    • Brentjens R, Rivière I, Park J, Davila M, Wang X, Stefanski J, Taylor C, Yeh R, Bartido S, Borquez-Ojeda O et al (2011) Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118:4817-4828
    • (2011) Blood , vol.118 , pp. 4817-4828
    • Brentjens, R.1    Rivière, I.2    Park, J.3    Davila, M.4    Wang, X.5    Stefanski, J.6    Taylor, C.7    Yeh, R.8    Bartido, S.9    Borquez-Ojeda, O.10
  • 32
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan R, Yang J, Kitano M, Dudley M, Laurencot C, Rosenberg S (2010) Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 18:843-851
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.1    Yang, J.2    Kitano, M.3    Dudley, M.4    Laurencot, C.5    Rosenberg, S.6
  • 33
    • 77956535599 scopus 로고    scopus 로고
    • Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
    • Jena B, Dotti G, Cooper L (2010) Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor. Blood 116:1035-1044
    • (2010) Blood , vol.116 , pp. 1035-1044
    • Jena, B.1    Dotti, G.2    Cooper, L.3
  • 34
    • 84899631361 scopus 로고    scopus 로고
    • Antibody modified T cells: CARs take the front seat for hematologic malignancies
    • Maus MV, Grupp SA, Porter DL, June CH (2014) Antibody modified T cells: CARs take the front seat for hematologic malignancies. Blood 123:2625-2635
    • (2014) Blood , vol.123 , pp. 2625-2635
    • Maus, M.V.1    Grupp, S.A.2    Porter, D.L.3    June, C.H.4
  • 35
    • 33845256434 scopus 로고    scopus 로고
    • T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells
    • DOI 10.1182/blood-2006-04-017061
    • Vera J, Savoldo B, Vigouroux S, Biagi E, Pule M, Rossig C, Wu J, Heslop HE, Rooney CM, Brenner MK et al (2006) T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood 108:3890-3897 (Pubitemid 44864573)
    • (2006) Blood , vol.108 , Issue.12 , pp. 3890-3897
    • Vera, J.1    Savoldo, B.2    Vigouroux, S.3    Biagi, E.4    Pule, M.5    Rossig, C.6    Wu, J.7    Heslop, H.E.8    Rooney, C.M.9    Brenner, M.K.10    Dotti, G.11
  • 36
    • 84895066532 scopus 로고    scopus 로고
    • Toxicity management for patients receiving novel T-cell engaging therapies
    • Barrett DM, Teachey DT, Grupp SA (2014) Toxicity management for patients receiving novel T-cell engaging therapies. Curr Opin Pediatr 26:43-49
    • (2014) Curr Opin Pediatr , vol.26 , pp. 43-49
    • Barrett, D.M.1    Teachey, D.T.2    Grupp, S.A.3
  • 37
    • 51249099119 scopus 로고    scopus 로고
    • Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome
    • Tang Y, Xu X, Song H, Yang S, Shi S, Wei J, Pan B, Zhao F, Liao C, Luo C (2008) Early diagnostic and prognostic significance of a specific Th1/Th2 cytokine pattern in children with haemophagocytic syndrome. Br J Haematol 143:84-91
    • (2008) Br J Haematol , vol.143 , pp. 84-91
    • Tang, Y.1    Xu, X.2    Song, H.3    Yang, S.4    Shi, S.5    Wei, J.6    Pan, B.7    Zhao, F.8    Liao, C.9    Luo, C.10
  • 41
    • 0029945194 scopus 로고    scopus 로고
    • Protection against lethal toxic shock by targeted disruption of the CD28 gene
    • DOI 10.1084/jem.183.6.2675
    • Saha B, Harlan DM, Lee KP, June CH, Abe R (1996) Protection against lethal toxic shock by targeted disruption of the CD28 gene. J Exp Med 183:2675-2680 (Pubitemid 26192377)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.6 , pp. 2675-2680
    • Saha, B.1    Harlan, D.M.2    Lee, K.P.3    June, C.H.4    Abe, R.5
  • 42
    • 84863522243 scopus 로고    scopus 로고
    • Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab
    • Klinger M, Brandl C, Zugmaier G, Hijazi Y, Bargou RC, Topp MS, Gokbuget N, Neumann S, Goebeler M, Viardot A et al (2012) Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab. Blood 119:6226-6233
    • (2012) Blood , vol.119 , pp. 6226-6233
    • Klinger, M.1    Brandl, C.2    Zugmaier, G.3    Hijazi, Y.4    Bargou, R.C.5    Topp, M.S.6    Gokbuget, N.7    Neumann, S.8    Goebeler, M.9    Viardot, A.10
  • 45
    • 84878921225 scopus 로고    scopus 로고
    • A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell engagers (BiTEs)
    • Stone JD, Aggen DH, Schietinger A, Schreiber H, Kranz DM (2012) A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell engagers (BiTEs). Oncoimmunology 1:863-873
    • (2012) Oncoimmunology , vol.1 , pp. 863-873
    • Stone, J.D.1    Aggen, D.H.2    Schietinger, A.3    Schreiber, H.4    Kranz, D.M.5
  • 46
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
    • Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S (2000) Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol 74:181-273
    • (2000) Adv Immunol , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 49
    • 84884230890 scopus 로고    scopus 로고
    • Blockade of TGF-beta signaling greatly enhances the efficacy of TCR gene therapy of cancer
    • Bendle GM, Linnemann C, Bies L, Song JY, Schumacher TN (2013) Blockade of TGF-beta signaling greatly enhances the efficacy of TCR gene therapy of cancer. J Immunol 191:3232-3239
    • (2013) J Immunol , vol.191 , pp. 3232-3239
    • Bendle, G.M.1    Linnemann, C.2    Bies, L.3    Song, J.Y.4    Schumacher, T.N.5
  • 52
    • 84880170261 scopus 로고    scopus 로고
    • Perspective: Assembly line immunotherapy
    • Levine BL, June CH (2013) Perspective: assembly line immunotherapy. Nature 498:S17
    • (2013) Nature , vol.498
    • Levine, B.L.1    June, C.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.