Cryptochinones from Cryptocarya chinensis act as farnesoid X receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 17, 2014, Pages 4181-4186

  Lin, Hsiang Ru ^a   Chou, Tsung Hsien ^b   Huang, Din Wen ^c   Chen, Ih Sheng ^b  

^a NATIONAL KAOHSIUNG NORMAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

Author keywords

Cryptocarya chinensis; Cryptochinones; Farnesoid X receptor (FXR); Nuclear receptor

Indexed keywords

ANDROGEN RECEPTOR; CHENODEOXYCHOLIC ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CRYPTOCHINONE A; CRYPTOCHINONE B; CRYPTOCHINONE C; CRYPTOCHINONE D; ESTROGEN RECEPTOR; FARNESOID X RECEPTOR; FARNESOID X RECEPTOR AGONIST; HORMONE RECEPTOR AFFECTING AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN TYROSINE PHOSPHATASE SHP; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; FLAVANONE DERIVATIVE;

ARTICLE; CRYPTOCARYA; CRYPTOCARYA CHINENSIS; GENETIC TRANSCRIPTION; HEPG2 CELL LINE; HUMAN; MOLECULAR MODEL; PROMOTER REGION; RECEPTOR BINDING; AGONISTS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ISOLATION AND PURIFICATION; STRUCTURE ACTIVITY RELATION;

CRYPTOCARYA CHINENSIS; MAMMALIA;

CRYPTOCARYA; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVANONES; HEP G2 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84906935844     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.07.045     Document Type: Article

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