4-Phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic β-cell apoptosis in rats with streptozotocin-induced diabetes

Endocrine

Volumn 47, Issue 1, 2014, Pages 129-137

  Zhu, Min ^a   Guo, Mei ^a   Fei, Li ^a   Pan, Xiao Qin ^a   Liu, Qian Qi ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

4 Phenylbutyric acid; Apoptosis; Endoplasmic reticulum stress; Pancreatic cells

Indexed keywords

4 PHENYLBUTYRIC ACID; CASPASE 3; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DIET RESTRICTION; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; MALE; MICROARRAY ANALYSIS; MICROSCOPY; MORPHOLOGY; NICK END LABELING; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SPRAGUE DAWLEY RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WESTERN BLOTTING; ANIMAL; DOWN REGULATION; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CYTOPROTECTION; DIABETES MELLITUS, EXPERIMENTAL; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; INSULIN-SECRETING CELLS; MALE; PHENYLBUTYRATES; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN;

EID: 84906933734     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-013-0132-7     Document Type: Article

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