Synthesis and optimization of a novel polymeric micelle based on hyaluronic acid and phospholipids for delivery of paclitaxel, in vitro and in-vivo evaluation

International Journal of Pharmaceutics

Volumn 475, Issue 1-2, 2014, Pages 163-173

  Saadat, Ebrahim ^a   Amini, Mohsen ^a   Khoshayand, Mohammad Reza ^a   Dinarvand, Rassoul ^a   Dorkoosh, Farid A ^a,b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Biodistribution; D optimal design; Drug delivery; Hyaluronic acid; Paclitaxel; Polymeric micelle; Real time imaging

Indexed keywords

1,2 DIMIRISTOYL PHOSPHATIDYLETHANOLAMINE; 1,2 DISTEAROYL PHOSPHATIDYLETHANOLAMINE; HYALURONIC ACID; PACLITAXEL; PHOSPHOLIPID; UNCLASSIFIED DRUG; 1,2-DIMYRISTOYLPHOSPHATIDYLETHANOLAMINE; 1,2-DISTEAROYLPHOSPHATIDYLETHANOLAMINE; ANTINEOPLASTIC AGENT; DRUG CARRIER; FLUORESCENT DYE; MICELLE; PHOSPHATIDYLETHANOLAMINE;

ANIMAL EXPERIMENT; ARTICLE; DEPENDENT VARIABLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SYNTHESIS; HEART; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MICELLE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SPLEEN; TEMPERATURE; ANIMAL; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; DRUG FORMULATION; DRUG STABILITY; DRUG STORAGE; FLUORESCENCE IMAGING; METABOLISM; SOLUBILITY; TISSUE DISTRIBUTION; WHOLE BODY IMAGING; CONTROLLED STUDY; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; DRUG STORAGE; FLUORESCENT DYES; HYALURONIC ACID; MICELLES; MODELS, CHEMICAL; OPTICAL IMAGING; PACLITAXEL; PARTICLE SIZE; PHOSPHATIDYLETHANOLAMINES; PHYSICOCHEMICAL PHENOMENA; RATS; SOLUBILITY; TISSUE DISTRIBUTION; WHOLE BODY IMAGING;

EID: 84906933043     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.08.030     Document Type: Article

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