Quantification of gastrointestinal liquid volumes and distribution following a 240 mL dose of water in the fasted state

Molecular Pharmaceutics

Volumn 11, Issue 9, 2014, Pages 3039-3047

  Mudie, Deanna M ^a   Murray, Kathryn ^b   Hoad, Caroline L ^b   Pritchard, Susan E ^b   Garnett, Martin C ^b   Amidon, Gordon L ^a   Gowland, Penny A ^b   Spiller, Robin C ^c   Amidon, Gregory E ^a   Marciani, Luca ^c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

bioperformance; dissolution; gastric emptying; intestinal water; MRI; small bowel

Indexed keywords

WATER;

ADULT; BIOAVAILABILITY; DIET RESTRICTION; EATING; FEMALE; HUMAN; INTESTINE ABSORPTION; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; PROCEDURES; SMALL INTESTINE; SOLUBILITY; STOMACH; STOMACH EMPTYING; TISSUE DISTRIBUTION; YOUNG ADULT;

ADULT; BIOLOGICAL AVAILABILITY; EATING; FASTING; FEMALE; GASTRIC EMPTYING; HUMANS; INTESTINAL ABSORPTION; INTESTINE, SMALL; MAGNETIC RESONANCE IMAGING; MALE; SOLUBILITY; STOMACH; TISSUE DISTRIBUTION; WATER; YOUNG ADULT;

EID: 84906901999     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500210c     Document Type: Article

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