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Volumn 144, Issue 9, 2014, Pages 1378-1384

Carob pod insoluble fiber exerts anti-atherosclerotic effects in rabbits throughsirtuin-1 and peroxisome proliferator-activated receptor-γ coactivator-1α

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLESTEROL; COCONUT OIL; COLLAGEN TYPE 1; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PLASMINOGEN ACTIVATOR INHIBITOR 1; SIRTUIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; ALGAROBA; AUTACOID; CHOLESTEROL INTAKE; GALACTAN; MANNAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME-PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA COACTIVATOR-1; PLANT GUM; TRANSCRIPTION FACTOR; VEGETABLE OIL;

EID: 84906895245     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.196113     Document Type: Article
Times cited : (26)

References (47)
  • 1
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. Atherosclerosis. Nature 2000;407:233-41.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 2
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002;420:868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 4
    • 0029661985 scopus 로고    scopus 로고
    • Pathogenic mechanisms of atherosclerosis: effect of lipid lowering on the biology of atherosclerosis
    • Ganz P, Creager MA, Fang JC,McConnell MV, Lee RT, Libby P, Selwyn AP. Pathogenic mechanisms of atherosclerosis: effect of lipid lowering on the biology of atherosclerosis. Am J Med 1996;101:4A10S-16S.
    • (1996) Am J Med , vol.101 , pp. 4A10S-4A16S
    • Ganz, P.1    Creager, M.A.2    Fang, J.C.3    McConnell, M.V.4    Lee, R.T.5    Libby, P.6    Selwyn, A.P.7
  • 7
    • 79951881254 scopus 로고    scopus 로고
    • Protective roles of SIRT1 in atherosclerosis
    • Stein S, Matter CM. Protective roles of SIRT1 in atherosclerosis. Cell Cycle 2011;10:640-7.
    • (2011) Cell Cycle , vol.10 , pp. 640-647
    • Stein, S.1    Matter, C.M.2
  • 8
    • 84870211276 scopus 로고    scopus 로고
    • SIRT1-an anti-inflammatory pathway at the crossroads between metabolic disease and atherosclerosis
    • Winnik S, Stein S, Matter CM. SIRT1-an anti-inflammatory pathway at the crossroads between metabolic disease and atherosclerosis. Curr Vasc Pharmacol 2012;10:693-6.
    • (2012) Curr Vasc Pharmacol , vol.10 , pp. 693-696
    • Winnik, S.1    Stein, S.2    Matter, C.M.3
  • 9
    • 77953355431 scopus 로고    scopus 로고
    • SIRT1/eNOS axis as a potential target against vascular senescence, dysfunction and atherosclerosis
    • Ota H, Eto M, Ogawa S, Iijima K, Akishita M, Ouchi Y. SIRT1/eNOS axis as a potential target against vascular senescence, dysfunction and atherosclerosis. J Atheroscler Thromb 2010;17:431-5.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 431-435
    • Ota, H.1    Eto, M.2    Ogawa, S.3    Iijima, K.4    Akishita, M.5    Ouchi, Y.6
  • 11
  • 13
    • 33845596500 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
    • Handschin C, Spiegelman BM. Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev 2006;27:728-35.
    • (2006) Endocr Rev , vol.27 , pp. 728-735
    • Handschin, C.1    Spiegelman, B.M.2
  • 14
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin J, Handschin C, Spiegelman BM. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 2005;1:361-70.
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 15
    • 19444365211 scopus 로고    scopus 로고
    • PGC- 1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells
    • Valle I, Alvarez-Barrientos A, Arza E, Lamas S, Monsalve M. PGC- 1alpha regulates the mitochondrial antioxidant defense system in vascular endothelial cells. Cardiovasc Res 2005;66:562-73.
    • (2005) Cardiovasc Res , vol.66 , pp. 562-573
    • Valle, I.1    Alvarez-Barrientos, A.2    Arza, E.3    Lamas, S.4    Monsalve, M.5
  • 16
    • 33846463967 scopus 로고    scopus 로고
    • Effects of PGC-1alpha on TNF-alphainduced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells
    • Kim HJ, Park KG, Yoo EK, Kim YH, Kim YN, Kim HS, Kim HT, Park JY, Lee KU, Jang WG, et al. Effects of PGC-1alpha on TNF-alphainduced MCP-1 and VCAM-1 expression and NF-kappaB activation in human aortic smooth muscle and endothelial cells. Antioxid Redox Signal 2007;9:301-7.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 301-307
    • Kim, H.J.1    Park, K.G.2    Yoo, E.K.3    Kim, Y.H.4    Kim, Y.N.5    Kim, H.S.6    Kim, H.T.7    Park, J.Y.8    Lee, K.U.9    Jang, W.G.10
  • 19
    • 85172654665 scopus 로고    scopus 로고
    • [database on the Internet]. Updated Jun 1 [cited 2014 May 1]. Available from:
    • The Statistical Division of the Food and Agriculture Organization of the United Nations [database on the Internet]. Updated 2014 Jun 1 [cited 2014 May 1]. Available from: http://faostat.fao.org/site/339/ default.aspx.
    • (2014)
  • 20
    • 0642307075 scopus 로고    scopus 로고
    • Dietary fiber and progression of atherosclerosis: the Los Angeles Atherosclerosis Study
    • Wu H, Dwyer KM, Fan Z, Shircore A, Fan J, Dwyer JH. Dietary fiber and progression of atherosclerosis: the Los Angeles Atherosclerosis Study. Am J Clin Nutr 2003;78:1085-91.
    • (2003) Am J Clin Nutr , vol.78 , pp. 1085-1091
    • Wu, H.1    Dwyer, K.M.2    Fan, Z.3    Shircore, A.4    Fan, J.5    Dwyer, J.H.6
  • 22
    • 0032944280 scopus 로고    scopus 로고
    • Cholesterol-lowering effects of dietary fiber: a meta-analysis
    • Brown L, Rosner B, Willett WW, Sacks FM. Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J Clin Nutr 1999;69:30-42.
    • (1999) Am J Clin Nutr , vol.69 , pp. 30-42
    • Brown, L.1    Rosner, B.2    Willett, W.W.3    Sacks, F.M.4
  • 24
    • 0141885331 scopus 로고    scopus 로고
    • Carob pulp preparation rich in insoluble fibre lowers total and LDL cholesterol in hypercholesterolemic patients
    • Zunft HJ, Luder W, Harde A, Haber B, Graubaum HJ, Koebnick C, Grunwald J. Carob pulp preparation rich in insoluble fibre lowers total and LDL cholesterol in hypercholesterolemic patients. Eur J Nutr 2003;42:235-42.
    • (2003) Eur J Nutr , vol.42 , pp. 235-242
    • Zunft, H.J.1    Luder, W.2    Harde, A.3    Haber, B.4    Graubaum, H.J.5    Koebnick, C.6    Grunwald, J.7
  • 25
    • 77949541094 scopus 로고    scopus 로고
    • Insoluble carob fiber rich in polyphenols lowers total and LDL cholesterol in hypercholesterolemic subjects
    • Ruiz-Roso B, Quintela JC, de la Fuente E, Haya J, Perez-Olleros L. Insoluble carob fiber rich in polyphenols lowers total and LDL cholesterol in hypercholesterolemic subjects. Plant Foods Hum Nutr 2010;65:50-6.
    • (2010) Plant Foods Hum Nutr , vol.65 , pp. 50-56
    • Ruiz-Roso, B.1    Quintela, J.C.2    de la Fuente, E.3    Haya, J.4    Perez-Olleros, L.5
  • 26
    • 0018419104 scopus 로고
    • Influence of tannin-rich carob pod fiber on the cholesterol metabolism in the rat
    • Wu¨rsch P. Influence of tannin-rich carob pod fiber on the cholesterol metabolism in the rat. J Nutr 1979;109:685-92.
    • (1979) J Nutr , vol.109 , pp. 685-692
    • Wu¨rsch, P.1
  • 27
    • 33646817108 scopus 로고    scopus 로고
    • Carob pulp preparation rich in insoluble dietary fiber and polyphenols enhances lipid oxidation and lowers postprandial acylated ghrelin in humans
    • Gruendel S, Garcia AL, Otto B, Mueller C, Steiniger J, Weickert MO, Speth M, Katz N, Koebnick C. Carob pulp preparation rich in insoluble dietary fiber and polyphenols enhances lipid oxidation and lowers postprandial acylated ghrelin in humans. J Nutr 2006;136: 1533-8.
    • (2006) J Nutr , vol.136 , pp. 1533-1538
    • Gruendel, S.1    Garcia, A.L.2    Otto, B.3    Mueller, C.4    Steiniger, J.5    Weickert, M.O.6    Speth, M.7    Katz, N.8    Koebnick, C.9
  • 28
    • 36649019538 scopus 로고    scopus 로고
    • Increased acylated plasma ghrelin, but improved lipid profiles 24-h after consumption of carob pulp preparation rich in dietary fibre and polyphenols
    • Gruendel S, Garcia AL, Otto B, Wagner K, Bidlingmaier M, Burget L, Weickert MO, Dongowski G, Speth M, Katz N, et al. Increased acylated plasma ghrelin, but improved lipid profiles 24-h after consumption of carob pulp preparation rich in dietary fibre and polyphenols. Br J Nutr 2007;98:1170-7.
    • (2007) Br J Nutr , vol.98 , pp. 1170-1177
    • Gruendel, S.1    Garcia, A.L.2    Otto, B.3    Wagner, K.4    Bidlingmaier, M.5    Burget, L.6    Weickert, M.O.7    Dongowski, G.8    Speth, M.9    Katz, N.10
  • 31
    • 0037391214 scopus 로고    scopus 로고
    • Comparison between the effects of mixed dyslipidaemia and hypercholesterolaemia on endothelial function, atherosclerotic lesions and fibrinolysis in rabbits
    • de las Heras N, Cediel E, Oubina MP, Aragoncillo P, Sanz-Rosa D, Lahera V, Cachofeiro V. Comparison between the effects of mixed dyslipidaemia and hypercholesterolaemia on endothelial function, atherosclerotic lesions and fibrinolysis in rabbits. Clin Sci (Lond) 2003;104:357-65.
    • (2003) Clin Sci (Lond) , vol.104 , pp. 357-365
    • de Las Heras, N.1    Cediel, E.2    Oubina, M.P.3    Aragoncillo, P.4    Sanz-Rosa, D.5    Lahera, V.6    Cachofeiro, V.7
  • 33
    • 84864290237 scopus 로고    scopus 로고
    • The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer
    • Kaczmarczyk MM, Miller MJ, Freund GG. The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer. Metabolism 2012;61: 1058-66.
    • (2012) Metabolism , vol.61 , pp. 1058-1066
    • Kaczmarczyk, M.M.1    Miller, M.J.2    Freund, G.G.3
  • 34
    • 26044452076 scopus 로고    scopus 로고
    • Mechanisms of cholesterol-lowering effects of dietary insoluble fibres: relationships with intestinal and hepatic cholesterol parameters
    • van Bennekum AM, Nguyen DV, Schulthess G, Hauser H, Phillips MC. Mechanisms of cholesterol-lowering effects of dietary insoluble fibres: relationships with intestinal and hepatic cholesterol parameters. Br J Nutr 2005;94:331-7.
    • (2005) Br J Nutr , vol.94 , pp. 331-337
    • van Bennekum, A.M.1    Nguyen, D.V.2    Schulthess, G.3    Hauser, H.4    Phillips, M.C.5
  • 35
    • 18544409991 scopus 로고    scopus 로고
    • Comparative study of natural carob fibre and psyllium husk in rats. Influence on some aspects of nutritional utilisation and lipidaemia
    • Perez-Olleros L, Garcia-Cuevas M, Ruiz-Roso B, Requejo A. Comparative study of natural carob fibre and psyllium husk in rats. Influence on some aspects of nutritional utilisation and lipidaemia. J Sci Food Agric 1999;79:173-8.
    • (1999) J Sci Food Agric , vol.79 , pp. 173-178
    • Perez-Olleros, L.1    Garcia-Cuevas, M.2    Ruiz-Roso, B.3    Requejo, A.4
  • 36
    • 57849104714 scopus 로고    scopus 로고
    • Particle size reduction effectively enhances the cholesterol-lowering activities of carrot insoluble fiber and cellulose
    • Chou SY, Chien PJ, Chau CF. Particle size reduction effectively enhances the cholesterol-lowering activities of carrot insoluble fiber and cellulose. J Agric Food Chem 2008;56:10994-8.
    • (2008) J Agric Food Chem , vol.56 , pp. 10994-10998
    • Chou, S.Y.1    Chien, P.J.2    Chau, C.F.3
  • 38
    • 0036040929 scopus 로고    scopus 로고
    • Effects of fibrates on serum metabolic parameters
    • Elisaf M. Effects of fibrates on serum metabolic parameters. Curr Med Res Opin 2002;18:269-76.
    • (2002) Curr Med Res Opin , vol.18 , pp. 269-276
    • Elisaf, M.1
  • 39
    • 47649116533 scopus 로고    scopus 로고
    • Cholesterol lowering is more important than pleiotropic effects of statins for endothelial function in patients with dysglycaemia and coronary artery disease
    • Settergren M, Bohm F, Ryden L, Pernow J. Cholesterol lowering is more important than pleiotropic effects of statins for endothelial function in patients with dysglycaemia and coronary artery disease. Eur Heart J 2008;29:1753-60.
    • (2008) Eur Heart J , vol.29 , pp. 1753-1760
    • Settergren, M.1    Bohm, F.2    Ryden, L.3    Pernow, J.4
  • 42
    • 84863543188 scopus 로고    scopus 로고
    • Dietary oats and modulation of atherogenic pathways
    • Andersson KE, Hellstrand P. Dietary oats and modulation of atherogenic pathways. Mol Nutr Food Res 2012;56:1003-13.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 1003-1013
    • Andersson, K.E.1    Hellstrand, P.2
  • 43
    • 54149118238 scopus 로고    scopus 로고
    • Activating SIRT1: a new strategy to prevent atherosclerosis?
    • Brandes RP. Activating SIRT1: a new strategy to prevent atherosclerosis? Cardiovasc Res 2008;80:163-4.
    • (2008) Cardiovasc Res , vol.80 , pp. 163-164
    • Brandes, R.P.1
  • 44
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation 2004;109:III27-32.
    • (2004) Circulation , vol.109 , pp. 327-332
    • Davignon, J.1    Ganz, P.2
  • 46
    • 3943054839 scopus 로고    scopus 로고
    • The Sir2 family of protein deacetylases
    • Blander G, Guarente L. The Sir2 family of protein deacetylases. Annu Rev Biochem 2004;73:417-35.
    • (2004) Annu Rev Biochem , vol.73 , pp. 417-435
    • Blander, G.1    Guarente, L.2
  • 47
    • 54149103338 scopus 로고    scopus 로고
    • Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
    • Zhang QJ,Wang Z, Chen HZ, Zhou S, ZhengW, Liu G,Wei YS, Cai H, Liu DP, Liang CC. Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res 2008;80:191-9.
    • (2008) Cardiovasc Res , vol.80 , pp. 191-199
    • Zhang, Q.J.1    Wang, Z.2    Chen, H.Z.3    Zhou, S.4    Zheng, W.5    Liu, G.6    Wei, Y.S.7    Cai, H.8    Liu, D.P.9    Liang, C.C.10


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