Structural characterization of human cholesterol 7α-hydroxylase

Journal of Lipid Research

Volumn 55, Issue 9, 2014, Pages 1925-1932

  Tempel, Wolfram ^a   Grabovec, Irina ^b   MacKenzie, Farrell ^a   Dichenko, Yaroslav V ^b   Usanov, Sergey A ^b   Gilep, Andrei A ^b   Park, Hee Won ^c   Strushkevich, Natallia ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

^c TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytochrome P450; Oxysterols; X ray crystallography CYP7A1

Indexed keywords

7-KETOCHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLESTEROL DERIVATIVE; CYP7A1 PROTEIN, HUMAN; ENZYME INHIBITOR; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; HUMAN; HYDROGEN BOND; HYDROXYLATION; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CHOLESTEROL 7-ALPHA-HYDROXYLASE; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; HYDROGEN BONDING; HYDROXYLATION; KETOCHOLESTEROLS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY;

EID: 84906883780     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M050765     Document Type: Article

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