Protective effects of hericium erinaceus mycelium and its isolated erinacine a against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine

International Journal of Molecular Sciences

Volumn 15, Issue 9, 2014, Pages 15073-15089

  Lee, Kam Fai ^a   Chen, Jiann Hwa ^b,c,d   Teng, Chih Chuan ^e   Shen, Chien Heng ^a   Hsieh, Meng Chiao ^a,f   Lu, Chien Chang ^a,f   Lee, Ko Chao ^a,f   Lee, Li Ya ^g   Chen, Wan Ping ^g   Chen, Chin Chu ^g   Huang, Wen Shih ^a,f   Kuo, Hsing Chun ^e  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d CATHAY GENERAL HOSPITAL   (Taiwan)

^e CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^f CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^g Grape King Biotechnology Inc   (Taiwan)

Author keywords

Erinacine A; Hericium erinaceus; iNOS; Ischemia reperfusion; Neuroprotection

Indexed keywords

3-NITROTYROSINE; CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; DITERPENE; ERINACINE A; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROPROTECTIVE AGENT; TYROSINE;

ANALOGS AND DERIVATIVES; ANIMAL; BASIDIOMYCETES; BRAIN ISCHEMIA; CELL DEATH; CHEMISTRY; DRUG EFFECTS; GENETICS; MALE; METABOLISM; MYCELIUM; NERVE CELL; RAT; REPERFUSION INJURY; SPRAGUE DAWLEY RAT;

ANIMALS; BASIDIOMYCOTA; BRAIN ISCHEMIA; CCAAT-ENHANCER-BINDING PROTEINS; CELL DEATH; CYTOKINES; DITERPENES; MALE; MYCELIUM; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TRANSCRIPTION FACTOR CHOP; TYROSINE;

EID: 84906837681     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150915073     Document Type: Article

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